Uvavanyo lwegazi lweAldosterone

Uvavanyo lwealdosterone lwegazi lilinganisa inqanaba lehormone aldosterone egazini.

I-Aldosterone nayo inokulinganiswa kusetyenziswa uvavanyo lomchamo.

Isampulu yegazi iyafuneka.

Umboneleli wakho wezempilo angakucela ukuba uyeke ukuthatha amayeza athile kwiintsuku ezimbalwa phambi kovavanyo ukuze zingachaphazeli iziphumo zovavanyo. Qiniseka ukuba uxelela umboneleli wakho ngawo onke amayeza owathathayo. Oku kubandakanya:

• Amayeza oxinzelelo lwegazi
• Amayeza entliziyo
• Izidakamizwa ezichasayo ezichasayo (i-NSAID)
• Amayeza e-Antacid kunye nezilonda
• Iipilisi zamanzi (i-diuretics)

Sukuyeka ukuthatha naliphi na iyeza ngaphambi kokuba uthethe nogqirha wakho. Umboneleli wakho unokucebisa ukuba ungadli ngaphezulu kwe-3 gram yetyuwa (isodiyam) ngemini ubuncinci iiveki ezi-2 ngaphambi kovavanyo.

Okanye, umboneleli wakho uya kukucebisa ukuba utye isixa sakho setyuwa kwaye uvavanye inani le-sodium kumchamo wakho.

Ngamanye amaxesha, uvavanyo lwegazi lwe-aldosterone lwenziwa kanye ngaphambi nasemva kokufumana isisombululo setyuwa (i-saline) nge-vein (IV) iiyure ezimbini. Yazi ukuba ezinye izinto zinokuchaphazela imilinganiselo ye-aldosterone, kubandakanya:

• Ukukhulelwa
• Ukutya okuphezulu okanye okuphantsi kwesodium
• Ukutya okuphezulu okanye okuphantsi kwe-potassium
• Ukuzilolonga kakhulu
• Uxinzelelo

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva ngathi batyhafile okanye batyhafile. Emva koko, kunokubakho ukubetha okanye ukukrala kancinci. Oku kuya kuhamba kungekudala.

Olu vavanyo luyalelwe le miqathango ilandelayo:

• Ukuphazamiseka okuthile kwe-fluid kunye ne-electrolyte, ihlala iphantsi okanye iphakamileyo nge-sodium okanye i-potassium encinci
• Kunzima ukulawula uxinzelelo lwegazi
• Uxinzelelo lwegazi oluphantsi xa umile (i-orthostatic hypotension)

I-Aldosterone yincindi yedlala ekhutshwa ziintsholongwane. Inceda umzimba ulawule uxinzelelo lwegazi. I-Aldosterone yonyusa ukubuyiselwa kwesodiyamu kunye namanzi kunye nokukhutshwa kwe potassium kwizintso. Eli nyathelo liphakamisa uxinzelelo lwegazi.

Uvavanyo lwegazi lwe-Aldosterone luhlala ludityaniswa nezinye iimvavanyo, ezinje ngovavanyo lwehomoni ye-renin, ukufumanisa ukuba ungaphantsi okanye ungaphantsi kwemveliso ye-aldosterone.

Amanqanaba aqhelekileyo ahluka:

• Phakathi kwabantwana, ulutsha, kunye nabantu abadala
• Kuxhomekeke ekubeni ubumi, uhleli, okanye ulele phantsi xa kutsalwa igazi

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Inqanaba eliphezulu kune-aldosterone enokubakho ngenxa:

• Isifo seBartter (iqela leemeko ezinqabileyo ezichaphazela izintso)
• Amadlala adrenal akhupha i-aldosterone hormone eninzi (i-hyperaldosteronism ephambili- ihlala ibangelwa yi-nodule ye-adrenal gland)
• Ukutya okunesodiyamu ephantsi kakhulu
• Ukuthatha amayeza oxinzelelo lwegazi abizwa ngokuba ngabachasi be-mineralocorticoid

Inqanaba elisezantsi kuneliqhelekileyo le-aldosterone linokubakho ngenxa:

• Ukuphazamiseka kwamadlala, kubandakanya ukungakhuphi ngokwaneleyo i-aldosterone, kunye nemeko ebizwa ngokuba kukungoneliseki kwe-adrenal yokuqala (isifo iAddison)
• Ukutya okunesodiyam ephezulu kakhulu

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka kwisigulana esinye ukuya kwelinye nakwelinye icala lomzimba liye kwelinye. Ukuthatha igazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

IAldosterone - iserum; Isifo iAddison - serum aldosterone; Isiseko sehyperaldosteronism - serum aldosterone; Isifo seBartter-serum aldosterone

Unonophelo RM, uPadia SH. Ukuphazamiseka okungaphezulu kwemaminerocorticoid kunye noxinzelelo lwegazi. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, ii-eds. Endocrinology: Abantu abadala kunye nabantwana. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 108.

UGuber HA, uFarag AF. Uvavanyo lomsebenzi we-endocrine. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 24.