Impendulo ye-LH kuvavanyo lwegazi lwe-GnRH

Impendulo ye-LH kwi-GnRH luvavanyo lwegazi ukunceda ukumisela ukuba isifo sakho se-pituitary singaphendula ngokuchanekileyo kwi-gonadotropin ekhupha i-hormone (GnRH). I-LH imele i-luteinizing hormone.

Kuthathwa isampulu yegazi, emva koko unikwe umfanekiso weGnRH. Emva kwexesha elichaziweyo, iisampulu zegazi ezininzi zithathwa ukuze i-LH ikwazi ukulinganiswa.

Akukho lungiselelo lukhethekileyo luyimfuneko.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukukrala kancinci. Oku kuya kuhamba kungekudala.

I-GnRH yincindi yedlala eyenziwe yindlala yehypothalamus. I-LH yenziwa yidlala yebhinqa. I-GnRH ibangela (ivuselele) i-pituitary gland ukukhupha i-LH.

Olu vavanyo lusetyenziselwa ukuxelela umahluko phakathi kwe-hypogonadism yamabanga aphantsi kunye nasesekondari. I-Hypogonadism yimeko apho amadlala esini enza i-hormone encinci okanye engenawo kwaphela. Emadodeni, amadlala esini (iigonads) luvavanyo. Kwabasetyhini, amadlala esini zii-ovari.

Kuxhomekeka kuhlobo lwe-hypogonadism:

• I-hypogonadism yaseprayimari iqala kwisende okanye kwi-ovary
• I-hypogonadism yesibini iqala kwi-hypothalamus okanye kwi-pituitary gland

Olu vavanyo lunokwenziwa ukujonga:

• Inqanaba le testosterone eliphantsi emadodeni
• Inqanaba le-estradiol esezantsi kwabasetyhini

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho wezempilo malunga nentsingiselo yeziphumo zakho zovavanyo.

Impendulo eyandisiweyo ye-LH iphakamisa ingxaki kwii-ovari okanye kwiimvavanyo.

Impendulo encitshisiweyo ye-LH iphakamisa ingxaki kwi-hypothalamus gland okanye i-pituitary gland.

Iziphumo ezingaqhelekanga zinokubangelwa:

• Iingxaki ze-pituitary gland, njengokukhutshwa kwehomoni eninzi (hyperprolactinemia)
• Amathumba amakhulu ebhinqa
• Ukuhla kwehomoni eyenziwe ngamadlala endocrine
• Intsimbi eninzi emzimbeni (hemochromatosis)
• Ukuphazamiseka kwindlela yokutya, njengeanorexia
• Kutshanje ukunciphisa umzimba, njengasemva koqhaqho lwe-bariatric
• Ukulibaziseka okanye ukungabikho kobuntwana (Isifo seKallmann)
• Ukungabikho kwamaxesha kwabasetyhini (amenorrhea)
• Ukutyeba kakhulu

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye nakwelinye icala lomzimba liye kwelinye. Ukuthatha igazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Ukuphendula impendulo yehomoni kwi-gonadotropin-ekhulula ihomoni

UGuber HA, uFarag AF. Uvavanyo lomsebenzi we-endocrine. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 24.

I-Haisenleder DJ, uMarshall JC. I-Gonadotropins: ukulawulwa kokudibana kunye nokugcinwa kwemfihlo. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, ii-eds. Endocrinology: Abantu abadala kunye nabantwana. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; I-2016: isahluko 116.