Uvavanyo lwe-DHEA-sulfate

I-DHEA imele i-dehydroepiandrosterone. Yehomoni yamadoda ebuthathaka (androgen) eveliswa ziincindi zeadrenal emadodeni nakwabasetyhini. Uvavanyo lwe-DHEA-sulfate lilinganisa inani le-DHEA-sulfate egazini.

Isampulu yegazi iyafuneka.

Akukho lungiselelo lukhethekileyo luyimfuneko. Nangona kunjalo, xelela umboneleli wakho wezempilo ukuba uthatha naziphi na iivithamini okanye izongezo eziqukethe i-DHEA okanye i-DHEA-sulfate.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba nje okanye behlaba. Emva koko, kunokubakho ukubetha okanye ukukrala kancinci. Oku kuya kuhamba kungekudala.

Olu vavanyo lwenziwa ukujonga ukusebenza kwamadlala amabini adrenal. Elinye lala madlala lihleli ngaphezulu kwentso nganye. Yeyona mithombo iphambili ye-androgens kwabasetyhini.

Nangona i-DHEA-sulfate yeyona hormone ininzi emzimbeni, eyona nto isebenzayo ayikaziwa.

• Emadodeni, isiphumo sehomoni eyindoda sinokungabaluleki ukuba inqanaba le testosterone liqhelekile.
• Kwabasetyhini, i-DHEA inegalelo kwi-libido eqhelekileyo kunye nolwaneliseko ngokwesondo.
• I-DHEA inokuba nefuthe kumajoni omzimba.

Uvavanyo lwe-DHEA-sulphate luhlala lusenziwa kwabasetyhini ababonisa iimpawu zokuba neehomoni ezingaphezulu kwendoda. Eminye yale miqondiso lutshintsho lomzimba wobudoda, ukukhula okungaphezulu kweenwele, ulusu olunamafutha, amabala, amaxesha angaqhelekanga, okanye iingxaki zokukhulelwa.

Inokwenziwa nakwabasetyhini abanenkxalabo malunga ne-libido ephantsi okanye ukunciphisa ukoneliseka ngokwesondo abanesifo se-pituitary okanye i-adrenal gland.

Uvavanyo luyenziwa nakubantwana abavuthwa kwangoko (ukufikisa kwangaphambili).

Amanqanaba egazi aqhelekileyo e-DHEA-sulphate anokuhluka ngokwabelana ngesondo kunye nobudala.

Iindidi eziqhelekileyo zabasetyhini zezi:

• Iminyaka eyi-18 ukuya kwi-19: 145 ukuya kwi-395 yeekhilogram kwi-deciliter (µg / dL) okanye kwi-3.92 ukuya kwi-10.66 yeemicroles kwilitha nganye (i-olmol / L)
• Iminyaka engama-20 ukuya kuma-29: 65 ukuya ku-380 µg / dL okanye ngo-1.75 ukuya ku-10.26 µmol / L
• Iminyaka engama-30 ukuya kuma-39: 45 ukuya ku-270 µg / dL okanye u-1.22 ukuya ku-7.29 µmol / L
• Iminyaka engama-40 ukuya kuma-49: 32 ukuya ku-240 µg / dL okanye ngo-0.86 ukuya ku-6.48 µmol / L.
• Iminyaka engama-50 ukuya kuma-59: 26 ukuya kuma-200 µg / dL okanye ngo-0.70 ukuya ku-5.40 µmol / L.
• Iminyaka engama-60 ukuya kuma-69: 13 ukuya kwi-130 µg / dL okanye kwi-0.35 ukuya kwi-3.51 µmol / L.
• Iminyaka engama-69 nangaphezulu: 17 ukuya kwi-90 µg / dL okanye kwi-0.46 ukuya kwi-2.43 µmol / L.

Iindidi eziqhelekileyo zamadoda zezi:

• Iminyaka ye-18 ukuya kwi-19: 108 ukuya kwi-441 µg / dL okanye kwi-2.92 ukuya kwi-11.91 µmol / L
• Iminyaka engama-20 ukuya kuma-29: 280 ukuya ku-640 µg / dL okanye ngo-7.56 ukuya ku-17.28 µmol / L
• Iminyaka engama-30 ukuya kuma-39: 120 ukuya ku-520 µg / dL okanye ngo-3.24 ukuya ku-14.04 olmol / L.
• Iminyaka engama-40 ukuya kuma-49: 95 ukuya ku-530 i-µg / dL okanye i-2.56 ukuya kwi-14.31 µmol / L
• Iminyaka engama-50 ukuya kuma-59: 70 ukuya kuma-310 µg / dL okanye u-1.89 ukuya ku-8.37 µmol / L
• Iminyaka engama-60 ukuya kuma-69: 42 ukuya kuma-290 µg / dL okanye i-1.13 ukuya kwi-7.83 olmol / L
• Iminyaka engama-69 nangaphezulu: 28 kuye kwi-175 µg / dL okanye kwi-0.76 ukuya kwi-4.72 µmol / L

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho wezempilo malunga nentsingiselo yeziphumo zakho zovavanyo.

Ukonyuka kwe-DHEA-sulfate kunokubangelwa:

• Isifo esiqhelekileyo semfuza esibizwa ngokuba yi-congenital adrenal hyperplasia.
• I-tumor ye-adrenal gland, enokuba yinto enobungozi okanye ibe ngumhlaza.
• Ingxaki eqhelekileyo kwabasetyhini abangaphantsi kweminyaka engama-50, ebizwa ngokuba yi-polycystic ovary syndrome.
• Utshintsho lomzimba wentombazana ekufikiseni eyenzeka ngaphambi kwexesha eliqhelekileyo.

Ukwehla kwe-DHEA sulfate kunokubangelwa:

• Ukuphazamiseka kwamadlala okuvelisa ezantsi kunexabiso eliqhelekileyo lehomoni yeadrenal, kubandakanya ukungoneliseki kweadrenal kunye nesifo iAddison
• Idlala lepituitary alivelisi ixabiso lesiqhelo lamahomoni alo (hypopituitarism)
• Ukuthatha amayeza e-glucocorticoid

Amanqanaba e-DHEA ahlala ehla kunye nobudala kumadoda nabasetyhini. Akukho bungqina bunokuthenjwa bokuba ukuthatha isongezelelo se-DHEA kuthintela iimeko ezinxulumene nokuguga.

Kukho umngcipheko omncinci ochaphazelekayo ekuthatheni igazi lakho: imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye kwaye ukusuka kwelinye icala lomzimba ukuya kwelinye. Ukufumana isampulu yegazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi elakhiweyo phantsi kolusu)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Iserum DHEA-sulfate; Uvavanyo lwe-Dehydroepiandrosterone-sulfate; I-DHEA-sulfate - serum

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IRosenfield RL, iBarnes RB, i-Ehrmann DA. Hyperandrogenism, hirsutism, kunye ne-polycystic ovary syndrome. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, ii-eds. Endocrinology: Abantu abadala kunye nabantwana. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; I-2016: isahluko 133.

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