Delavirdine

Umxholo

• Ngaphambi kokuba uthathe i-delavirdine,
• I-Delavirdine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, yeka ukuthatha i-delavirdine kwaye ubize ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

IDelavirdine ayisasebenzi eMelika.

I-Delavirdine isetyenziswa kunye namanye amayeza ukunyanga intsholongwane kaGawulayo. I-Delavirdine ikwiklasi yamayeza abizwa ngokuba yi-non-nucleoside reverse transcriptase inhibitors (NNRTIs). Isebenza ngokunciphisa inani le-HIV egazini. Nangona i-delavirdine ingayinyangi i-HIV, inokuwanciphisa amathuba akho okuba ne-immunodeficiency syndrome (i-AIDS) kunye nezifo ezinxulumene ne-HIV ezinje ngezifo ezinzulu okanye umhlaza. Ukuthatha la mayeza kunye nokwabelana ngesondo okukhuselekileyo nokwenza olunye utshintsho kwindlela yokuphila kunokunciphisa umngcipheko wokuhambisa (ukusasaza) intsholongwane kagawulayo kwabanye abantu.

I-Delavirdine iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kathathu ngemini kunye okanye ngaphandle kokutya. Thatha i-delavirdine ujikeleze amaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-delavirdine ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ukuba unengxaki yokuginya iipilisi ze-100-mg, zinokusasazeka emanzini. Ukulungiselela, faka iipilisi ezine ubuncinci kwii-ounces ezi-3 (90 milliliters) zamanzi, vumela ukuma okwemizuzu embalwa, emva koko unyanzelise de zonke iipilisi zinyibilike. Sela umxube wamanzi we-delavirdine-amanzi kwangoko. Hlanganisa iglasi kwaye uginye isiraphu ukuqinisekisa ukuba uyifumene yonke idosi. Amacwecwe angama-200-mg (amancinci kunamacwecwe ayi-100-mg) kufuneka asoloko eginyiwe, kuba awanyibiliki ngokulula emanzini.

Ugqirha wakho unokukuxelela ukuba uthathe iipilisi ze-delavirdine ngejusi ye-orenji okanye ye-cranberry ukuba uneemeko ezithile zonyango ezifana ne-achlorhydria (imeko apho isisu singenayo i-asidi encinci). Landela le miyalelo ngononophelo.

I-Delavirdine inokuyilawula i-HIV kodwa ayizukuyinyanga. Qhubeka nokuthatha i-delavirdine nokuba uziva uphilile. Sukuyeka ukuthatha i-delavirdine okanye amanye amayeza owasebenzisayo ukunyanga i-HIV okanye i-AIDS ungakhange uthethe nogqirha wakho. Xa unikezelo lwakho lwe-delavirdine luqala ukuba phantsi, fumana ngakumbi kugqirha wakho okanye kwikhemesti. Ukuba ulahlekelwa ngamanani okanye uyeke ukuthatha i-delavirdine, imeko yakho inokuba nzima ukunyanga.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

La mayeza ngamanye amaxesha amiselweyo kwezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-delavirdine,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-delavirdine, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze-delavirdine. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha ialprazolam (Xanax); ii-antihistamines ezithile ezinje nge-astemizole (Hismanal) (engasafumaneki e-U.S) kunye ne-terfenadine (Seldane) (engasekhoyo e-U.S); amayeza athile ohlobo lwe-ergot anje nge-dihydroergotamine (iDHE 45, Migranal), ergonovine (Ergotrate), ergotamine tartrate (Ergomar, eCafergot, eMigergot), kunye ne-methylergonovine (Methergine); i-cisapride (Propulsid) (engasekhoyo e-U.S.); midazolam (iVesi); ipimozide (Orap); kunye netriazolam (Halcion). Ugqirha wakho uya kukuxelela ukuba ungathathi i-delavirdine ukuba uthatha elinye okanye ngaphezulu kwala mayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: amphetamine ezifana neamphetamine (Adderall) kunye ne dextroamphetamine (Dexadrine, Dextrostat); ii-anticoagulants ('igazi elincinci)' njengewarfarin (Coumadin); ii-calcium channel blocker ezinje nge-amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop), nisoldipine , kunye neverapamil (Calan, Covera, Isoptin, Verelan); amayeza athile anyanga i-cholesterol ephezulu njenge-atorvastatin (Lipitor), cerivastatin (Baycol), fluvastatin (Lescol), lovastatin (Mevacor), kunye ne-simvastatin (Zocor); amayeza athile anyanga ukuxhuzula okufana ne-carbamazepine (Tegretol, Carbatrol), phenobarbital, kunye ne phenytoin (Dilantin, Phenytek); i-clarithromycin (i-Biaxin); i-cyclosporine (iNeoral, iSandimmune); dexamethasone (Decadron); ifluticasone (Flonase, Flovent, Veramyst); amayeza okubetha kwentliziyo ngokungaqhelekanga njenge-amiodarone (Cordarone), bepridil (Bepadin) (engasafumaneki e-US), lidocaine, quinidine, flecainide (Tambocor), kunye nepropafenone (Rythmol); amayeza okugaya isisu, ukutsha kwentliziyo, okanye izilonda ezinje nge-cimetidine (Tagamet), famotidine (Pepcid), lansoprazole (Prevacid), nizatidine (Axid), omeprazole (Prilosec), kunye ne-ranitidine (iZantac); imethadone (iDolophine, iMethadose); izinto zokucwangcisa ngomlomo (iipilisi zolawulo lokuzalwa); amanye amayeza okunyanga i-HIV kubandakanya i-didanosine (Videx), efavirenz (Sustiva, e-Atripla), etravirine (Intelence), indinavir (Crixivan), lopinavir (eKaletra), maraviroc (Selzentry), nelfinavir (Viracept), nevirapine (Viramune), i-rilpivirine (i-Edurant, eComplera), i-ritonavir (i-Norvir, e-Kaletra), kunye ne-saquinavir (i-Invirase); irifabutin (Mycobutin); irifampin (Rifadin, Rimactane, eRifamate, eRifater); iSildenafil (Viagra); i-sirolimus (iRapamune); itacrolimus (Prograf); kunye ne-trazodone (Desyrel). Uninzi lwamanye amayeza anokusebenzisana ne-delavirdine, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akujonge ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho kunye nosokhemisti ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi i-wort yaseSt. Akufanele uthathe i-wort yaseSt.John ngelixa uthatha i-delavirdine.
• ukuba uthatha i-didanosine (Videx), yithathe ubuncinci iyure enye ngaphambi okanye iyure e-1 emva kokuthatha i-delavirdine.
• ukuba uthatha ii-antacids, thabatha i-antacid okungenani iyure enye ngaphambi okanye iyure e-1 emva kokuthatha i-delavirdine.
• xelela ugqirha wakho ukuba unayo i-achlorhydria (imeko apho isisu singenayo i-asidi encinci) okanye isifo sesibindi okanye sezintso.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ukuba ukhulelwa ngelixa uthatha i-delavirdine, tsalela ugqirha wakho. Tshela ugqirha wakho ukuba uncelisa. Akufanelanga ukuncancisa xa wosulelwe yi-HIV okanye ukuba uthatha i-delavirdine.
• Kuya kufuneka uyazi ukuba amanqatha omzimba wakho anokunyuka okanye ahambele kwiindawo ezahlukeneyo zomzimba wakho ezinje ngamabele akho, umqolo ongasentla nentamo, okanye ujikeleze umbindi womzimba wakho. Ukuphulukana namafutha emilenzeni, ezingalweni nasebusweni nako kunokwenzeka.
• Kuya kufuneka uyazi ukuba ngelixa uthatha amayeza ukunyanga usulelo lwe-HIV, amajoni akho omzimba angomelela kwaye aqale ukulwa nezinye izifo ezazisele zisemzimbeni wakho. Oku kunokubangela ukuba ube neempawu zolu sulelo. Ukuba uneempawu ezintsha okanye eziba mandundu emva kokuqala unyango nge-delavirdine, qiniseka ukuxelela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo. Ukuba uphosa idosi ezininzi, tsalela ugqirha wakho akubuze ukuba kufuneka uqhubeke njani nokuthatha i-delavirdine.

I-Delavirdine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukudinwa kakhulu
• intloko ebuhlungu
• isicaphucaphu
• urhudo
• irhashalala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, yeka ukuthatha i-delavirdine kwaye ubize ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ukukhawuleza kunye nezinye iimpawu ezinjengomkhuhlane, ukutshiza, izilonda emlonyeni, amehlo abomvu okanye adumbileyo, okanye iintlungu zomzimba
• urhwebo
• ukurhawuzelela
• ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukudinwa
• ubunzima bokuphefumla okanye ukugwinya

I-Delavirdine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unokuyalela iimvavanyo ezithile zebhu ukujonga impendulo yakho kwi-delavirdine.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Umgcini-zincwadi^®