Uluhlu lwamagama

Umxholo

• I-Alendronate isenokungasebenzi kakuhle kwaye inokonakalisa i-esophagus (ityhubhu phakathi komlomo nesisu) okanye ibangele izilonda emlonyeni ukuba ayithathiwe ngokwale miyalelo ilandelayo. Xelela ugqirha wakho ukuba awuqondi, awucingi ukuba uyakukhumbula, okanye awungekhe ukwazi ukulandela le miyalelo:
• Ngaphambi kokuba uthathe i-alendronate,
• I-Alendronate inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwiCandelo LOKUGCINWA OKUQHELEKILEYO, tsalela ugqirha wakho kwangoko ngaphambi kokuba uthathe i-alendronate:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Alendronate isetyenziselwa ukunyanga nokukhusela i-osteoporosis (imeko apho amathambo esiba buthathaka kwaye aphelelwe ngamandla kwaye aphuke ngokulula) kwabasetyhini abaye bayeka ukuya exesheni ('' ukutshintsha kobomi, '' ukuphela kwexesha lokuya exesheni) nokunyanga i-osteoporosis emadodeni. I-Alendronate ikwasetyenziselwa ukunyanga i-osteoporosis emadodeni nakwabasetyhini abathatha i-corticosteroids (uhlobo lonyango olunokubangela i-osteoporosis kwezinye izigulana). I-Alendronate ikwasetyenziselwa ukunyanga isifo sePaget samathambo (imeko apho amathambo ethambile kwaye ebuthathaka kwaye anokukhubazeka, ababuhlungu, okanye aphuke ngokulula). I-Alendronate ikwiklasi yamayeza abizwa ngokuba yi-bisphosphonates. Isebenza ngokuthintela ukophuka kwethambo kunye nokwandisa uxinano lweethambo (ubukhulu).

I-Alendronate iza njengecwecwe, ithebhulethi esebenzayo, kunye nesisombululo (ulwelo) oluthathwa ngomlomo. Isisombululo sihlala sithathwa kwisisu esingenalutho kanye ngeveki ekuseni. Iipilisi ze-5-mg kunye ne-10-mg zihlala zithathwa kwisisu esingenalutho kanye ngemini kusasa, kwaye iipilisi ezingama-35-mg kunye ne-70-mg zihlala zithathwa ngaphandle kwesisu kanye ngeveki kusasa. Iipilisi ezingama-40-mg zihlala zithathwa kanye ngemini kusasa kangangeenyanga ezintandathu ukunyanga isifo sePaget samathambo. Amacwecwe e-effervescent ahlala ethathwa kwisisu esingenanto kanye ngeveki kusasa. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-alendronate ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

I-Alendronate isenokungasebenzi kakuhle kwaye inokonakalisa i-esophagus (ityhubhu phakathi komlomo nesisu) okanye ibangele izilonda emlonyeni ukuba ayithathiwe ngokwale miyalelo ilandelayo. Xelela ugqirha wakho ukuba awuqondi, awucingi ukuba uyakukhumbula, okanye awungekhe ukwazi ukulandela le miyalelo:

• Kuya kufuneka uthathe i-alendronate emva kokuba uvukile ebhedini kusasa, ngaphambi kokuba utye okanye usele nantoni na. Ungaze uthathe i-alendronate ngexesha lokulala okanye ngaphambi kokuba uvuke uphume ebhedini usuku olo.
• Emva kokuba uthathe i-alendronate, ungatyi, ungaseli, okanye uthathe amanye amayeza (kubandakanya iivithamini okanye ii-antacids) ubuncinci imizuzu engama-30. Sukulala phantsi ubuncinci imizuzu engama-30 emva kokuba uthathe i-alendronate. Hlala ume nkqo okanye ume nkqo de kube kudlule imizuzu engama-30 kwaye utye ukutya kwakho kokuqala kosuku.
• Ukuba uthatha amacwecwe e-alendronate, ginya icwecwe ngeglasi epheleleyo (i-6 ukuya kwi-8 yee-ounces (i-180 ukuya kwi-240 mL) yamanzi acocekileyo. Ungaze uthathe iipilisi ze-alendronate ngeti, ikofu, ijusi, ubisi, amanzi amaminerali, amanzi ahlwahlwazayo, okanye nayiphi na into engamanzi ngaphandle kwamanzi acocekileyo. Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli okanye uzityumze. Musa ukufunxa iipilisi.
• Ukuba uthatha isisombululo somlomo se-alendronate, sela ubuncinci ii-ounces (i-60 milliliters [1/4 indebe]) yamanzi emva kokuthatha isisombululo somlomo se-alendronate. Ungaze uthathe isisombululo se-alendronate ngeti, ikofu, ijusi, ubisi, amanzi amaminerali, amanzi ahlwahlwazayo, okanye nayiphi na into engamanzi ngaphandle kwamanzi acocekileyo.
• Ukuba uthatha amacwecwe e-alendronate effervescent, nyibilikisa ipilisi enye kwiglasi epheleleyo (ii-ounces eziyi-120 [mililitha ezingama-120]) zamanzi okusela acocekileyo, angenacarbon ngaphambi kokuba usele. Ungaze unyibilikise iipilisi ze-alendronate ze-effervescent ngeti, ikofu, ijusi, ubisi, amanzi amaminerali, amanzi ahlwahlwazayo, okanye nayiphi na into engamanzi ngaphandle kwamanzi acocekileyo. Lindela ubuncinci imizuzu emi-5 emva kokuyeka kwe-effervescence, vusa isisombululo kwimizuzwana eyi-10 kwaye uyisele. Musa ukuginya, unganyisi, okanye ukuhlafuna kwiipilisi ezisebenzayo.

I-Alendronate ilawula i-osteoporosis kunye nesifo sePaget samathambo kodwa asizinyangi ezi meko. Kungathatha iinyanga ezintathu okanye ngaphezulu ngaphambi kokuba ithambo lakho liqale ukwanda. I-Alendronate iyanceda ukunyanga nokukhusela i-osteoporosis kuphela ukuba ithathwa rhoqo. Qhubeka nokuthatha i-alendronate nokuba uziva uphilile. Sukuyeka ukuthatha i-alendronate ungakhange uthethe nogqirha wakho, kodwa thetha nogqirha wakho amaxesha ngamaxesha malunga nokuba usafuna ukuthatha i-alendronate.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-alendronate,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-alendronate okanye amanye amayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya oku kulandelayo: i-aspirin kunye nezinye iziyobisi ezichasayo (i-NSAIDs) ezinje nge-ibuprofen (Advil, Ibu-Tab, Motrin, ezinye) kunye ne-naproxen (Aleve, Naprelan, Naprosyn, nezinye); umhlaza chemotherapy; okanye ii-steroids zomlomo ezinje nge-dexamethasone, methylprednisolone (Medrol), kunye ne-prednisone (iRayos). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• ukuba uthatha nawaphi na amanye amayeza kubandakanya izongezo, iivithamini, okanye ii-antacids ngomlomo, zithathe okungenani imizuzu engama-30 emva kokuba uthathe i-alendronate.
• xelela ugqirha wakho ukuba awukwazi ukuhlala nkqo okanye ume nkqo kangangemizuzu engama-30, ukuba ukhe wanelizinga eliphantsi lecalcium egazini lakho, umngcipheko wokuphefumla ukutya okanye ulwelo emiphungeni, okanye ukuba unayo nayiphi na ingxaki kwi-esophagus yakho. Ugqirha wakho unokukuxelela ukuba akufuneki uthathe i-alendronate.
• xelela ugqirha wakho ukuba ufumana unyango lwe-radiation okanye ukuba unesondlo esine-sodium (ukuba uthatha iipilisi ze-effervescent); kwaye ukuba ubukhe wanayo okanye (anemia) (imeko apho iiseli ezibomvu zegazi zingazisi oksijini yaneleyo kuwo onke amalungu omzimba); inqanaba eliphantsi levithamini D emzimbeni wakho; ubunzima bokugwinya; isilungulela; izilonda okanye ezinye iingxaki zesisu; umhlaza; naluphi na uhlobo losulelo, ngakumbi emlonyeni wakho; iingxaki ngomlomo, ngamazinyo, okanye ngeentsini nayiphi na imeko ethintela igazi lakho ekunqandeni ngesiqhelo; okanye isifo samazinyo okanye sezintso.
• xelela ugqirha wakho ukuba ukhulelwe okanye uncelisa. Xelela ugqirha wakho ukuba ucwangcisa ukukhulelwa nanini na kwixa elizayo, kuba i-alendronate inokuhlala emzimbeni wakho iminyaka emva kokuyeka ukuyithatha. Biza ugqirha wakho ukuba ukhulelwe ngexesha okanye emva konyango lwakho.
• Kuya kufuneka uyazi ukuba i-alendronate inokubangela i-osteonecrosis yomhlathi (ONJ, imeko enzima yethambo lomhlathi), ngakumbi ukuba uqhaqho lwamazinyo okanye unyango ngelixa uthatha amayeza. Ugqirha wamazinyo kufuneka ahlolisise amazinyo akho kwaye enze naluphi na unyango olufunekayo, kubandakanya ukucoca okanye ukulungisa amazinyo afakelweyo ngendlela engeyiyo, ngaphambi kokuba uqale ukuthatha ialendronate. Qiniseka ukuba uhlamba amazinyo kwaye ucoce umlomo ngokufanelekileyo ngelixa uthatha i-alendronate. Thetha nogqirha wakho ngaphambi kokuba ufumane unyango lwamazinyo ngelixa uthatha eli yeza.
• Kuya kufuneka uyazi ukuba i-alendronate inokubangela amathambo aqatha, umsipha, okanye iintlungu ezidibeneyo. Unokuqala ukuziva le ntlungu ngaphakathi kweentsuku, iinyanga, okanye iminyaka emva kokuba uqale uthathe i-alendronate. Nangona olu hlobo lweentlungu lungaqala emva kokuba uthathe i-alendronate kangangexesha elithile, kubalulekile kuwe nogqirha wakho ukuba niqonde ukuba kunokubangelwa yi-alendronate. Biza ugqirha wakho ngoko nangoko ukuba ufumana iintlungu ezinzima nangaliphi na ixesha ngexesha lonyango lwakho kunye ne-alendronate. Ugqirha wakho angakuxelela ukuba uyeke ukuthatha i-alendronate kwaye iintlungu zakho zinokuhamba emva kokuba uyekile ukuthatha amayeza.
• thetha nogqirha wakho ngezinye izinto onokuzenza ukuthintela i-osteoporosis ekuphuhliseni okanye ekubandezelekeni. Ugqirha wakho uya kuthi kukuthintele ukutshaya nokusela izixa ezikhulu zotywala kwaye ulandele inkqubo eqhelekileyo yokuthwala ubunzima.

Kuya kufuneka utye kwaye usele ukutya okuninzi kunye neziselo ezityebileyo kwi-calcium kunye nevithamin D ngelixa uthatha i-alendronate. Ugqirha wakho uya kukuxelela ukuba kukuphi ukutya kunye neziphuzo eziyimithombo elungileyo yezi zondlo kunye nokuba zingaphi iinkonzo ozidingayo suku ngalunye. Ukuba ukufumanisa kunzima ukutya oku kutya ngokwaneleyo, xelela ugqirha wakho. Kwimeko apho, ugqirha wakho unokumisela okanye acebise isongezelelo.

Ukuba uphosa idosi ye-alendronate yakanye-yemihla ngemihla, ungayithathi kamva emini. Tsiba idosi ephosiweyo kwaye uthathe idosi enye ngentsasa elandelayo njengesiqhelo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

Ukuba uphosa idosi ye-alendronate yakanye ngeveki, thatha idosi kusasa emva kokuba ukhumbule. Emva koko buyela ekuthatheni idosi enye kube kanye ngeveki ngosuku lwakho olumiselweyo. Ungaze uthathe idosi ephindwe kabini ukuyenzela enye ephosiweyo, kwaye ungaze uthathe idosi enye ngosuku olunye.

I-Alendronate inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• isisu esibuhlungu
• ukuqhina
• urhudo
• irhasi
• ukudumba okanye ukugcwala esiswini
• utshintsho kwisakhono sokungcamla ukutya
• intloko ebuhlungu
• isiyezi
• ukudumba kwamalungu, izandla, okanye imilenze
• ukuxhamla izihlunu, ukujija, okanye iicampu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwiCandelo LOKUGCINWA OKUQHELEKILEYO, tsalela ugqirha wakho kwangoko ngaphambi kokuba uthathe i-alendronate:

• isitshisa esitsha okanye esibi
• kunzima ukugwinya
• intlungu ekuginyeni
• iintlungu zesifuba
• ukugabha kwegazi okanye ukugabha okujongeka njengendawo yekofu
• emnyama, ilindile, okanye ilindle eligazi
• ifiva
• i-blisters okanye i-peeling skin
• ukukhawuleza (kunokwenziwa kakubi ngokukhanya kwelanga)
• ukurhawuzelela
• urhwebo
• ukudumba kwamehlo, ubuso, imilebe, ulwimi, okanye umqala
• ubunzima bokuphefumla
• ukudinwa
• iintsini ezibuhlungu okanye ezidumbileyo
• ukukhululeka kwamazinyo
• ukuba ndindisholo okanye ukuziva unzima emhlathini
• ukuphilisa kakubi umhlathi
• iintlungu zamehlo
• buthuntu, iintlungu zibuhlungu esinqeni, emiphakathini, okanye emathangeni

Ukuthatha amayeza e-bisphosphonate anje nge-alendronate ye-osteoporosis inokunyusa umngcipheko wokuba wophule amathambo akho. Ungaziva iintlungu esinqeni, emthanjeni, okanye emathangeni kangangeeveki okanye iinyanga ngaphambi kokuba amathambo aqhekeke, kwaye ungafumanisa ukuba elinye okanye omabini amathambo akho aphukile nangona ungakhange uwe okanye ufumane olunye umothuko. Akuqhelekanga ukuba ithambo lethanga liphule kubantu abasempilweni, kodwa abantu abane-osteoporosis banokulophula eli thambo nokuba abathathi i-alendronate. Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-alendronate.

I-Alendronate inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Musa ukumisa isisombululo se-alendronate.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokudlula ngaphezulu, nika ixhoba iglasi yobisi kwaye ubize iziko lakho lolawulo lwetyhefu kwindawo yoku-1-800-222-1222. Ukuba ixhoba liye lawa okanye aliphefumli, tsalela umnxeba iinkonzo zongxamiseko zasekuhlaleni ngo-911. Sukuvumela ixhoba ukuba lilale phantsi kwaye ungazami ukuligabha ixhoba.

Iimpawu libanda kungaquka oku kulandelayo:

• isilungulela
• isicaphucaphu
• isisu esibuhlungu
• ukugabha kwegazi okanye ukugabha okujongeka njengendawo yekofu
• ubunzima bokuginya okanye iintlungu xa uginya
• enegazi okanye emnyama kunye nezitulo ezilindileyo

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unokuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-alendronate.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• IBinosto^®
• Ifosamax^®

• Ifosamax^® I-Plus D (equlathe iAlendronate, iCholecalciferol)