Inaliti yeMethylnaltrexone

Umxholo

• Ngaphambi kokusebenzisa inaliti ye-methylnaltrexone,
• Inaliti ye-Methylnaltrexone inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana olu phawu, yeka ukusebenzisa i-methylnaltrexone kwaye ubize ugqirha ngoko nangoko:
• Iimpawu libanda kungaquka oku kulandelayo:

Inaliti ye-Methylnaltrexone isetyenziselwa ukunyanga ukuqhina okubangelwa zii-opioid (narcotic) amayeza eentlungu kubantu abaneentlungu ezingapheliyo (eziqhubekayo) ezingabangelwa ngumhlaza kodwa ezinokuthi zihambelane nomhlaza wangaphambili okanye unyango lomhlaza. Isetyenziselwa ukunyanga ukuqhina okubangelwa ziiyeza ze-opioid kubantu abanesifo esiphambili okanye iintlungu zomhlaza ezisebenzayo. Inaliti ye-Methylnaltrexone ikwiklasi yamayeza abizwa ngokuba yi-opioid receptor antagonists. Isebenza ngokukhusela isisu kwiziphumo zonyango lwe-opioid (narcotic).

Inaliti ye-Methylnaltrexone iza njengesisombululo (ulwelo) sokufaka ngenaliti (phantsi kolusu). Xa isetyenziselwa ukunyanga ukuqhina okubangelwa ngamayeza e-opioid kubantu abaneentlungu ezingapheliyo (eziqhubekayo) ezingabangelwa ngumhlaza, zihlala zifakwa kanye ngemini. Xa isetyenziselwa ukunyanga ukuqunjelwa okubangelwa ngamayeza e-opioid kubantu abanesifo esigqithileyo okanye umhlaza, ihlala itofwa kanye ngalo lonke usuku njengoko kufuneka, kodwa inokusetyenziselwa kube kanye emva kweeyure ezingama-24 xa kufuneka. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa inaliti ye-methylnaltrexone kanye njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

Inaliti ye-Methylnaltrexone kufuneka isetyenziswe ngabantu abathatha amayeza e-opioid (narcotic). Thetha nogqirha wakho ukuba utshintsha kangakanani okanye uthatha kangaphi amayeza akho opioid. Ukuba uyeka ukuthatha amayeza e-opioid, kuya kufuneka uyeke ukusebenzisa inaliti ye-methylnaltrexone nayo.

Kuya kufuneka uyeke ukuthatha amanye amayeza e-laxative xa uqala ukusebenzisa inaliti ye-methylnaltrexone. Nangona kunjalo, qiniseka ukuba wazise ugqirha wakho ukuba inaliti ye-methylnaltrexone ayisebenzi kuwe emva kokuyisebenzisa kangangeentsuku ezi-3. Ugqirha wakho unokukuxelela ukuba uthathe amanye amayeza e-laxative.

Unokufaka inaliti ye-methylnaltrexone ngokwakho okanye ube nomhlobo okanye isalamane esenza inaliti. Yifundisise ngononophelo imiyalelo yomenzi echaza indlela yokulungisa kunye nokujova idosi ye-methylnaltrexone. Buza ugqirha wakho okanye usokhemesti akubonise okanye umntu oza kufaka inaliti iyeza ukuba ungalitofa njani. Qiniseka ukuba ubuza usokhemesti okanye ugqirha ukuba unayo nayiphi na imibuzo malunga nokulungiselela okanye ukujova eli yeza.

Inaliti yeMethylnaltrexone iza iisirinji ezikhethiweyo kunye neebhotile oza kuzisebenzisa ngeesirinji ezilahlwayo. Ibhotile inokuza kwitreyi enesirinji, okanye kungafuneka uthenge iisirinji ngokwahlukeneyo. Buza ugqirha wakho okanye usokhemesti ukuba unemibuzo malunga nohlobo lweesirinji oza kuzisebenzisa. Sebenzisa iisirinji ezizalisiweyo, iingqayi kunye neesirinji ezilahlwayo kube kanye. Lahla isirinji ekhethiweyo, okanye igutyana kunye nesirinji emva kosetyenziso olunye, nokuba azinalutho. Kufuneka zilahlwe kwisikhongozeli esinganyangekiyo ukuba singafikelelwa ngabantwana. Musa ukulahla isikhongozeli esingagqibelelanga sokugqobhoza kwinkunkuma yasekhaya okanye ekusetyenzisweni kwakhona. Thetha nogqirha wakho okanye usokhemesti malunga nendlela yokulahla isikhongozeli esinganyangekiyo.

Unokujova i-methylnaltrexone phantsi kolusu esiswini sakho okanye emathangeni. Ukuba omnye umntu uya kukujolela iyeza, loo mntu unokulifaka engalweni yakho ephezulu. Khetha indawo entsha ngalo lonke ixesha usebenzisa inaliti ye-methylnaltrexone. Sukujova i-methylnaltrexone kwindawo ethenda, igruzukile, ibomvu, okanye inzima. Kwakhona, musa ukujova kwiindawo ezinamanxeba okanye ezolula amanqaku.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango ngenaliti ye-methylnaltrexone kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ukufumana isiKhokelo seyeza.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa inaliti ye-methylnaltrexone,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-methylnaltrexone, nawaphi na amanye amayeza, okanye nasiphi na isithako se-methylnaltrexone injection. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya oku kulandelayo: Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wanaso okanye wakha wanesithintelo esiswini (ukubhloka emathunjini akho). Ugqirha wakho uya kukuxelela ukuba ungasebenzisi inaliti ye-methylnaltrexone.
• xelela ugqirha wakho ukuba ukhe wakha wanengxaki yesisu okanye yamathumbu kubandakanya isilonda esiswini (izilonda kwimbombo yesisu), umhlaza wesisu okanye isilonda, isifo sikaCrohn (imeko apho umzimba uhlasela khona umgca wokugaya ukutya , kubangela iintlungu, urhudo, ukunciphisa umzimba, kunye nefiva), i-diverticulitis (iipokotshi ezincinci kumngxunya wamathumbu amakhulu anokutsha), isifo sika-Ogilvie's (imeko apho kukho isisu), okanye izintso okanye isibindi isifo.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ukuba ukhulelwa ngelixa usebenzisa inaliti ye-methylnaltrexone, tsalela ugqirha wakho. Ukuba ufumana i-methylnaltrexone ngexesha lokukhulelwa kwakho, umntwana wakho unokufumana iimpawu zokurhoxa kwe-opioid.
• xelela ugqirha wakho ukuba uncelisa. Musa ukuncancisa xa usebenzisa inaliti ye-methylnaltrexone.
• Kuya kufuneka uyazi ukuba uninzi lwabantu lunokuhamba kwamathumbu kwimizuzu embalwa ukuya kwiiyure ezimbalwa emva kokusebenzisa inaliti ye-methylnaltrexone. Qiniseka ukuba ukufutshane kwigumbi lokuhlambela xa usebenzisa eli yeza.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Kubantu abathile eli yeza lisetyenziswa njengoko kufuneka, kodwa kwezinye izigulana eliyeza lisetyenziswa yonke imihla. Ukuba ugqirha wakho ukuxelele ukuba usebenzise inaliti ye-methylnaltrexone rhoqo, sebenzisa idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukusebenzisa idosi ephindwe kabini ukwenza eyilahlekileyo.

Inaliti ye-Methylnaltrexone inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intlungu zesisu
• irhasi
• isicaphucaphu
• ukugabha
• urhudo
• isiyezi
• ukubila
• Ukugodola
• ixhala
• ukuzamla
• ukungcangcazela
• ukufudumala okutshisayo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana olu phawu, yeka ukusebenzisa i-methylnaltrexone kwaye ubize ugqirha ngoko nangoko:

• urhudo oluqatha
• iintlungu ezinzima zesisu

Inaliti ye-Methylnaltrexone inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina la mayeza ebhokisini engenile, evaliwe ngokuqinileyo, kwaye kude nokufikelela kwabantwana. Yigcine kubushushu begumbi kwaye ungayifisi. Khusela ekukhanyeni. Ukuba uzoba i-methylnaltrexone phezulu kwisirinji kodwa ungakwazi ukuyisebenzisa kwangoko, isirinji inokugcinwa kubushushu begumbi ukuya kuthi ga kwiiyure ezingama-24. Isirinji ayifuni kukhuselwa ekukhanyeni ngeli xesha.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• isiyezi, ukuba nentloko elula, nokuf ’isiqaqa xa uvuka ngokukhawuleza kwindawo oxokileyo kuyo
• Ukugodola
• ukubila
• impumlo enemifinya
• urhudo
• intlungu zesisu
• ixhala
• ukuzamla
• ukwehla kwentlungu yokuphelisa iziphumo zonyango lwe-opioid

Gcina lonke ixesha lokudibana nogqirha wakho.

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Unxibelelaniso^®