Umbhali: Gregory Harris
Umhla Wokudalwa: 12 Utshazimpuzi 2021
Hlaziya Umhla: 21 Eyenkanga 2024
Anonim
Amiodarone, Sotalol, and Dofetilide - Class III Antiarrhythmics Mechanism of Action and Side Effects
Ividiyo: Amiodarone, Sotalol, and Dofetilide - Class III Antiarrhythmics Mechanism of Action and Side Effects

Umxholo

I-Dofetilide inokubangela ukuba intliziyo yakho ibethe ngokungaqhelekanga. Kuya kufuneka ubesesibhedlele okanye kwenye indawo apho unokujongwa ngokusondeleyo ngugqirha wakho ubuncinci iintsuku ezi-3 xa uqalisiwe okanye uqaliswa kwakhona kwi-dofetilide. Kubalulekile ukuba ufunde ulwazi ngesigulana osinike lona ngalo lonke ixesha uqala unyango nge-dofetilide.

I-Dofetilide isetyenziselwa ukunyanga ukubetha kwentliziyo okungaqhelekanga (kubandakanya i-fibrillation ye-atrial okanye i-atrial flutter). Kwiklasi yamayeza abizwa ngokuba yi-antiarrhythmics. Iphucula isingqi sentliziyo yakho ngokuphumla kwintliziyo egqithisileyo.

I-Dofetilide iza njengephilisi ukuyithatha ngomlomo. Ihlala ithathwa kabini ngemini, kodwa inokuthathwa kanye ngemini kubantu abaneemeko ezithile. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-dofetilide ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

I-Dofetilide ilawula izingqisho zentliziyo engaqhelekanga kodwa ayizinyangi. Qhubeka uthatha i-dofetilide nokuba uziva uphilile. Sukuyeka ukuthatha i-dofetilide ngaphandle kokuthetha nogqirha wakho.


La mayeza ngamanye amaxesha amiselweyo kwezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-dofetilide,

  • xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-dofetilide, nawaphi na amanye amayeza, okanye naziphi na izithako kwiifomsile ze-dofetilide. Buza usokhemesti wakho okanye ujonge ulwazi lomenzi wesigulana uluhlu lwezithako.
  • xelela ugqirha wakho ukuba uthatha i-cimetidine (Tagamet), dolutegravir (Tivicay), hydrochlorothiazide (Microzide, Oretic), hydrochlorothiazide kunye ne-triamterene (Dyazide, Maxzide), ketoconazole (Nizoral), megestrol (Megace), prochlorperazine (Compro, i-trimethoprim (Primsol), i-trimethoprim kunye ne-sulfamethoxazole (Bactrim, Septra, Sulfatrim), kunye ne-verapamil (Calan, Covera, Verelan). Ugqirha wakho uya kukuxelela ukuba ungathathi i-dofetilide ukuba uthatha elinye okanye ngaphezulu kwala mayeza.
  • xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: amiloride (Midamor); ii-antibiotics ezifana ne-erythromycin (EES, E-Mycin) kunye ne-norfloxacin (Noroxin); amayeza athile okubulala afana ne-fluconazole (Diflucan), itraconazole (Sporanox), kunye ne-ketoconazole (Nizoral); i-bepridil (iVascor); ii-cannabinoids ezinje nge-dronabinol (Marinol), nabilone (Cesamet) okanye intsangu (i-cannabis); idigoxin (Lanoxin); I-diltiazem (iCardizem, iCartia XT, iDilacor XR, iTaxtia XT, iTiazac); umchamo ('iipilisi zamanzi'); I-HIV protease inhibitors kubandakanya atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, e Kaletra), saquinavir (Invirase) kunye netipranavir (Aptivus) amayeza esifuba esifana nezafirlukast (Accolate); amayeza oxinzelelo, ukugula ngengqondo, okanye isicaphucaphu; amayeza eentliziyo ezingaqhelekanga ezifana ne-amiodarone (Cordarone, iPacerone); metformin (Fortamet, Glucophage, Glumetza, Riomet); nefazodone; okanye iquinine (iQualquin).
  • xelela ugqirha wakho ukuba ukhe okanye wakha wanayo i-QT syndrome (imeko eyonyusa umngcipheko wokuba nesifo sentliziyo esingaqhelekanga esinokubangela isiqaqa okanye ukufa ngesiquphe), okanye isifo sezintso.
  • xelela ugqirha wakho ukuba unorhudo olugqithisileyo, ukubila, ukugabha, ukuphelelwa ngumdla wokutya, okanye ukuncipha kwenxano okanye inqanaba eliphantsi le potassium egazini lakho, kwaye ukuba unayo okanye wakhe wanesifo sentliziyo okanye sesibindi.
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-dofetilide, tsalela ugqirha wakho.

Thetha nogqirha wakho malunga nokutya igrapefruit okanye ukusela ijusi yegrapefruit ngelixa uthatha i-dofetilide.


Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi yakho elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Dofetilide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • intloko ebuhlungu
  • iintlungu zesifuba
  • ukuqhawukelwa ngumphefumlo
  • isicaphucaphu
  • Iimpawu ezinjengomkhuhlane
  • isisu esibuhlungu
  • umqolo obuhlungu
  • ubunzima bokulala okanye ukulala

Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko:

  • ngokukhawuleza, ukubetha, okanye ukubetha kwentliziyo okungaqhelekanga
  • irhashalala
  • urhudo oluqatha
  • isiyezi okanye isiqaqa
  • ukubila okungaqhelekanga
  • ukugabha
  • Ukuphelelwa ngumdla wokutya
  • ukoma okwandileyo (ukusela ngaphezu kwesiqhelo)

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).


Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Intliziyo yakho isingqisho kufuneka ihlolwe rhoqo ukufumanisa impendulo yakho kwi-dofetilide. Ugqirha wakho uya kufuna ukulandela umsebenzi wezintso kunye nenqanaba legazi le-potassium ngokusondeleyo ngelixa uthatha i-dofetilide.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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Ukuhlaziywa kokugqibela-01/15/2016

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