Ezetimibe

Umxholo

• Ngaphambi kokuthatha i-ezetimibe,
• I-Ezetimibe inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba ufumana enye yazo, tsalela ugqirha ngokukhawuleza:

I-Ezetimibe isetyenziswa kunye notshintsho kwindlela yokuphila (ukutya, ukunciphisa umzimba, ukuzilolonga) ukunciphisa inani lecholesterol (into enamafutha) kunye nezinye izinto ezinamanqatha egazini. Ingasetyenziselwa yodwa okanye ngokudibeneyo ne-HMG-CoA reductase inhibitor (statin). U-Ezetimibe ukwiklasi yamayeza abizwa ngokuba ngamayeza athoba i-cholesterol. Isebenza ngokuthintela ukufunxwa kwecholesterol emathunjini.

Ukwakhiwa kwecholesterol kunye namafutha ecaleni kweendonga zemithambo yegazi (inkqubo eyaziwa ngokuba yi-atherosclerosis) inciphisa ukuhamba kwegazi, okunciphisa ukubonelelwa kweoksijini entliziyweni, kwingqondo nakwamanye amalungu omzimba. Ukunciphisa amanqanaba egazi e-cholesterol kunye namafutha kunokunceda ukunciphisa oku kwakha kwaye kunokunciphisa amathuba akho okuphuhlisa iimeko zentliziyo ezifana ne-angina (intlungu yesifuba), ukubetha, kunye nokuhlaselwa yintliziyo. Iziphumo zophononongo lweklinikhi oluthelekisa abantu abathathe i-ezetimibe kunye ne-simvastatin nabantu abathathe i-simvastatin bodwa bafumanisa ukuba nangona iqela labantu abathatha i-ezetimibe kunye ne-simvastatin babenexabiso eliphantsi le-cholesterol egazini, kwakungekho mahluko phakathi kwala maqela mabini kwisixa yecholesterol kunye nokwakhiwa kwamanqatha ngaphakathi kwimithambo yegazi entanyeni. Okwangoku akuqondakali ukuba kutheni ukongezwa kwamanqanaba e-cholesterol egazini kungakhokeleli ekunciphiseni okukhulu kwecholesterol kunye nokwakha amanqatha ezindongeni zemithambo yegazi kubantu abathatha i-ezetimibe kunye ne-simvastatin. Izifundo ezongezelelweyo ziyaqhubeka ukuthelekisa unyango kunye ne-ezetimibe kunye ne-simvastatin kunyango lwe-simvastatin kuphela ukubona ukuba ukhona umahluko kumngcipheko wokuba nesifo sentliziyo. Thetha nogqirha wakho ukuba unemibuzo malunga nobungozi kunye nezibonelelo zokunyusa inani le-cholesterol egazini lakho nge-ezetimibe kunye namanye amayeza.

Ukongeza ekuthatheni iyeza lokunciphisa i-cholesterol, ukwenza utshintsho oluthile kwimikhwa yakho yemihla ngemihla kunokunciphisa amanqanaba egazi egazini. Kuya kufuneka utye ukutya okunezinto ezinamafutha amaninzi kunye ne-cholesterol (jonga i-SPECIAL DIETARY); sebenzisa imizuzu engama-30 kuninzi, ukuba akunjalo, iintsuku; kwaye unciphise umzimba ukuba ukhuluphele.

I-Ezetimibe iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye ngemini kunye okanye ngaphandle kokutya. Ukukunceda ukhumbule ukuthatha i-ezetimibe, yithathe ngexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-ezetimibe ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Qhubeka nokuthatha i-ezetimibe nokuba uziva uphilile. Sukuyeka ukuthatha i-ezetimibe ungakhange uthethe nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuthatha i-ezetimibe,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-ezetimibe okanye nawaphi na amanye amayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye neemveliso zamayeza owathathayo. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: ii-anticoagulants ('' blood thinner '') ezifana ne-warfarin (Coumadin); i-cyclosporine (iNeoral, iSandimmune); fenofibrate (TriCor); kunye ne-gemfibrozil (Lopid). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• ukuba uthatha icholestyramine (Questran), colesevelam (WellChol), okanye colestipol (Colestid), yithathe iiyure ezi-4 ngaphambi okanye iiyure ezi-2 emva kwe-ezetimibe.
• xelela ugqirha wakho ukuba ukhe unesifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-ezetimibe, biza ugqirha wakho.

Yitya ukutya okune-fat-fat, low-cholesterol. Qiniseka ukuba ulandela yonke imithambo kunye nezincomo zokutya ezenziwe ngugqirha wakho okanye ugqirha otya ukutya. Ungandwendwela iNational Cholesterol Education Programme (NCEP) kwiwebhusayithi ukufumana ulwazi olongezelelekileyo malunga nokutya kule http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Ezetimibe inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• isiyezi
• urhudo
• umqala obuhkungu
• impumlo enemifinya
• Ukuthimla
• intlungu edibeneyo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba ufumana enye yazo, tsalela ugqirha ngokukhawuleza:

• urhwebo
• irhashalala
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya
• ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukudinwa
• isisu esimoshakele
• ukudinwa kakhulu
• ukopha okungaqhelekanga okanye ukugruzuka
• ukunqongophala kwamandla
• Ukuphelelwa ngumdla wokutya
• iintlungu kwinxalenye ephezulu yesisu
• mthubi ulusu okanye amehlo
• Iimpawu ezinjengomkhuhlane
• iintlungu zemisipha okanye ubuthathaka
• ifiva
• Ukugodola
• ilindle eliluthuthu okanye elinamafutha
• iintlungu zesifuba

I-Ezetimibe inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zelebhu ngaphambi nangexesha lonyango ukujonga impendulo yomzimba wakho kwi-ezetimibe.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Zetia^®

• ILiptruzet^® (iqulethe iAtorvastatin, i-Ezetimibe)
• Nexlizet^® (Iqulethe iBempedoic Acid, Ezetimibe)
• IVithorin^® (iqulethe i-Ezetimibe, Simvastatin)