I-Interferon Beta-1a Inaliti yangaphantsi

Umxholo

• Ngaphambi kokusebenzisa i-interferon beta-1a,
• I-interferon beta-1a yangaphantsi enokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

I-Interferon beta-1a inaliti yesikhumba esetyenziselwa ukunyanga abantu abadala ngeendlela ezahlukeneyo ze-multiple sclerosis (MS; isifo apho imithambo-luvo ingasebenzi kakuhle kwaye abantu banokufumana ubuthathaka, ukuba ndindisholo, ukuphulukana nokulungelelaniswa kwezihlunu, kunye neengxaki ngombono, intetho, nolawulo lwesinyi) kubandakanya:

• I-CIS; Iimpawu zempawu zemithambo-luvo ezihlala ubuncinci iiyure ezingama-24),
• Iifom zokuphinda zibuyele kwakhona (ikhosi yesifo apho iimpawu ziyavela khona amaxesha ngamaxesha), okanye
• iifomati zesekondari eziqhubekayo (ikhosi yesifo apho ukubuyela umva kwenzeka rhoqo).

I-Interferon beta-1a ikudidi lwamayeza abizwa ngokuba zii-immunomodulators. Isebenza ngokunciphisa ukudumba kunye nokuthintela ukonakala kwemithambo-luvo kunokubangela iimpawu ze-multiple sclerosis.

I-Interferon beta-1a inaliti yangaphantsi ifika njengesisombululo (ulwelo) kwisirinji ekhethiweyo okanye isixhobo sokufaka inaliti esizenzekelayo ukuze sitofe (ngaphantsi kolusu). Ihlala itofwe kathathu ngeveki. Kuya kufuneka ulitofe eli chiza kwiintsuku ezi-3 ngeveki, umzekelo, rhoqo ngoMvulo, ngoLwesithathu nangoLwesihlanu. Inaliti kufuneka zishiyane iiyure ezingama-48 ubuncinci, ke kungcono ukuba utofe amayeza akho ngexesha elifanayo losuku ngalunye lweentsuku zakho zokutofa. Elona xesha lilungileyo lokufaka eli yeza emva kwemini okanye ngokuhlwa. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa i-interferon beta-1a ngokuchanekileyo njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

Ugqirha wakho unokukuqala ngedosi esezantsi ye-interferon beta-1a kwaye ngokuthe ngcembe wandise idosi yakho, hayi ngaphezulu kwesinye kwiiveki ezi-2.

I-Interferon beta-1a ilawula iimpawu ze-MS kodwa ayiyinyangi. Qhubeka nokusebenzisa i-interferon beta-1a nokuba uziva uphilile. Musa ukuyeka ukusebenzisa i-interferon beta-1a ngaphandle kokuthetha nogqirha wakho.

Uya kufumana idosi yakho yokuqala ye-interferon beta-1a engaphantsi kwiofisi kagqirha wakho. Emva koko unokufaka i-interferon beta-1a ngokwakho okanye ube nomhlobo okanye isalamane esenza inaliti. Buza ugqirha wakho okanye usokhemesti akubonise okanye umntu oza kufaka inaliti iyeza ukuba ungalitofa njani. Ngaphambi kokuba usebenzise i-interferon beta-1a engaphantsi kwesikhumba okokuqala, wena okanye umntu oza kunika inaliti kufuneka naye afunde ulwazi lomenzi wesigulana esiza nayo. Landela izikhokelo ngononophelo.

Sebenzisa isirinji ekhethiweyo okanye isixhobo esenziwe ngenaliti esizenzekelayo ngalo lonke ixesha utofa iyeza lakho. Sukuphinda usebenzise okanye wabelane ngeesirinji okanye izixhobo ezizenzekelayo. Nokuba kusekho isisombululo esishiyekileyo kwisirinji okanye isixhobo emva kokuba utofile, ungaphindi ufake inaliti kwakhona. Lahla iisirinji ezisetyenzisiweyo okanye izixhobo ezizenzekelayo zenaliti kwisitya esomeleleyo esingafikeleli ebantwaneni. Thetha nogqirha wakho okanye usokhemesti malunga nendlela yokulahla isikhongozeli esinganyangekiyo.

Ngalo lonke ixesha jonga amayeza kwisirinji oyithandayo okanye isixhobo esizenzekelayo ngaphambi kokuba uyisebenzise. Kuya kufuneka kucace kwisisombululo esityheli kancinane. Ukuba isisombululo sinamafu, sibala, okanye siqulathe amasuntswana okanye ukuba umhla wokuphelelwa uphawulwe kwisirinji okanye isixhobo sokuzenzekelayo sidlulile, ungasisebenzisi isirinji okanye isixhobo.

Thetha nogqirha wakho okanye usokhemesti malunga nokuba kuphi emzimbeni wakho ekufuneka utofe i-interferon beta-1a subcutaneous. Ungayifaka i-beta-1a ye-interferon kwiindawo zomzimba wakho ngamanqatha phakathi kolusu kunye nesihlunu, esifana nethanga lakho, umphezulu wengalo yakho ephezulu, isisu sakho, okanye iimpundu zakho. Ukuba ubhityile, jola kuphela ethangeni lakho okanye kumphezulu wengalo yakho ngenaliti. Khetha indawo eyahlukileyo ngalo lonke ixesha utofa iyeza lakho. Gcina irekhodi yomhla kunye nendawo yenaliti nganye. Sukusebenzisa indawo enye amaxesha amabini elandelelana. Sukujoba kufutshane nenkaba yakho (isisu sakho) okanye esinqeni okanye kwindawo apho ulusu lubuhlungu, lubomvu, luye lwatyumka, lunezikrobo, lusulelekile okanye aluqhelekanga nangayiphi na indlela.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seMithi) xa uqala unyango nge-interferon beta-1a inaliti engaphantsi kwaye ngalo lonke ixesha uzalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa i-interferon beta-1a,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-interferon beta-1a, naliphi na elinye iyeza le-interferon (Avonex, Betaseron, Extavia, Plegridy), nawaphi na amanye amayeza, okanye i-albin yabantu. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba uyasela okanye wakha wasela izixa ezikhulu zotywala; ukuba ukhe unesifo sokuzimela komzimba (isifo apho umzimba uhlasela iiseli ezizezaso, buza ugqirha wakho ukuba awuqinisekanga ukuba unolu hlobo lwesifo); i-anemia (iiseli ezibomvu ezisezantsi) okanye iiseli ezimhlophe ezisezantsi; iingxaki zegazi ezinjengokutyunyuzwa ngokulula okanye ukopha; ukugula ngengqondo njengoxinzelelo, ngakumbi ukuba ukhe wacinga ngokuzibulala okanye uzame ukwenza njalo; ukuxhuzula; ukumelwa yintliziyo; okanye intliziyo, intso, isibindi, okanye isifo se-thyroid.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa usebenzisa i-interferon beta-1a subcutaneous, tsalela ugqirha ngokukhawuleza.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo usebenzisa i-interferon beta-1a subcutaneous.
• buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kotywala ngelixa usebenzisa i-interferon beta-1a engaphantsi. Utywala bunokwenza iziphumo ebezingalindelekanga ze-interferon beta-1a ibe mandundu.
• Kuya kufuneka uyazi ukuba unokuba neempawu ezifana nomkhuhlane njengentloko, umkhuhlane, ukugodola, ukubila, iintlungu zemisipha, iintlungu zomqolo, kunye nokudinwa emva kwenaliti yakho. Ugqirha wakho unokukuxelela ukuba uthathe i-pain-the-counter kunye neyeza lomkhuhlane ukuze uncede kwezi mpawu. Ezi mpawu zihlala ziphucula okanye zihamba ngokuhamba kwexesha. Thetha nogqirha wakho ukuba ezi mpawu kunzima ukuzilawula okanye ziqine.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Faka isitofu esilahlekileyo ngokukhawuleza nje emva kokuba usikhumbule. Ukuba ucwangciselwe idosi ngosuku olulandelayo, tsiba idosi. Musa ukufaka i-interferon beta-1a kwisithuba seentsuku ezi-2 zilandelelana. Musa ukufaka idosi ephindwe kabini ukwenza idosi ephosiweyo. Kuya kufuneka ubuyele kwishedyuli yakho yeedosi kwiveki elandelayo. Biza ugqirha wakho ukuba uphose idosi kwaye unemibuzo malunga nokwenza.

I-interferon beta-1a yangaphantsi enokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• ifiva
• Ukugodola
• amehlo owomileyo
• iingxaki zombono
• umlomo owomileyo
• ukugruzuka, iintlungu, ukuba bomvu, ukudumba, okanye ukuthamba kwindawo yenaliti

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• uxinzelelo olutsha okanye olubi
• ucinga ngokuzenzakalisa okanye ukuzibulala okanye ukucwangcisa okanye ukuzama ukwenza njalo
• ixhala
• urhwebo
• irhashalala
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya
• ukudumba kwamehlo, ubuso, umlomo, ulwimi, umqala, izandla, iingalo, iinyawo, amaqatha okanye imilenze esezantsi
• intloko elula
• isiqaqa
• ukuxhuzula
• ukulahleka koququzelelo
• ukudinwa kakhulu
• ukunqongophala kwamandla
• isicaphucaphu
• ukugabha
• Ukuphelelwa ngumdla wokutya
• izitulo ezimhlophe
• iintlungu kwinxalenye ephezulu yesisu
• mthubi ulusu okanye amehlo
• umchamo omnyama
• ulusu oluthuthu
• iintlungu zesifuba
• ukubetha kwentliziyo ngokukhawuleza
• ukugruzuka okanye ukopha okungaqhelekanga
• umqala obuhlungu, ukukhohlela, umkhuhlane, ukubanda, okanye ezinye iimpawu zosulelo
• ukuzuza ubunzima okanye ilahleko engachazwanga
• uziva ubanda okanye ushushu ngalo lonke ixesha
• ubumnyama besikhumba okanye umjelo wamanzi kwindawo yenaliti
• ezibomvu okanye ezinegazi okanye urhudo
• isisu esibuhlungu
• intetho ecothayo okanye enzima
• Amachaphaza amfusa okanye amachaphaza amancinci (irhashalala) kulusu
• ukuncipha kokuchama okanye igazi kumchamo

I-Interferon beta-1a inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kwifriji, kodwa ungayiginyi. Ukuba ifriji ayifumaneki, unokugcina amayeza kwiqondo lobushushu egumbini kude nobushushu kunye nokukhanya kangangeentsuku ezingama-30.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-interferon beta-1a inaliti engaphantsi.

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Ukuhlaziya^®