Ribavirin

Umxholo

• Ngaphambi kokuba uthathe i-ribavirin,
• IRibavirin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba ufumana enye yazo, okanye ezo zidweliswe kwicandelo LESILumkiso ESIBALULEKILEYO, tsalela ugqirha wakho ngokukhawuleza:

I-Ribavirin ayizukunyanga i-hepatitis C (intsholongwane eyosulela isibindi kwaye inokubangela ukonakala kwesibindi okanye umhlaza wesibindi) ngaphandle kokuba ithathe elinye iyeza. Ugqirha wakho uya kukuyalela elinye iyeza ukuba ulisebenzise kunye ne-ribavirin ukuba une-hepatitis C. Thatha la mayeza omabini ngokuchanekileyo.

I-Ribavirin inokubangela i-anemia (imeko apho kukho ukuhla kwenani leeseli ezibomvu zegazi) ezinokuthi zenze mandundu naziphi na iingxaki zentliziyo onazo kwaye zinokubangela ukuba ube nesifo sentliziyo esinokubusongela ubomi. Xelela ugqirha wakho ukuba ukhe wahlaselwa sisifo sentliziyo kwaye ukhe waba noxinzelelo lwegazi oluphezulu, iingxaki zokuphefumla, nayiphi na imeko echaphazela igazi lakho njenge-sickle cell anemia (imeko ezuzwe njengelifa apho iiseli ezibomvu zegazi zimile ngokungaqhelekanga kwaye ayinakho ukuzisa ioksijini kuwo onke amalungu omzimba) okanye thalassemia (iMeditera anemia; imeko apho iiseli ezibomvu zegazi zingenanto eyaneleyo yokuthwala ioksijini), ukopha esiswini okanye emathunjini, okanye isifo sentliziyo. Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: ukudinwa okugqithisileyo, isikhumba esiluthuthu, intloko ebuhlungu, isiyezi, ukudideka, ukubetha kwentliziyo okukhawulezayo, ubuthathaka, ukuphefumla kancinci, okanye iintlungu esifubeni.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo zegazi ngaphambi kokuba uqale ukuthatha i-ribavirin kwaye rhoqo ngexesha lonyango lwakho.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lomguli lomenzi (Isikhokelo seMithi) xa uqala unyango nge-ribavirin kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ukufumana isiKhokelo seyeza.

Thetha nogqirha wakho malunga neengozi zokuthatha i-ribavirin.

Kwabaguli ababhinqileyo:

Musa ukuthatha i-ribavirin ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Akufanele uqale ukuthatha i-ribavirin de uvavanyo lokukhulelwa lubonise ukuba awukhulelwe. Kuya kufuneka usebenzise iindlela ezimbini zolawulo lokuzalwa kwaye kuvavanywe ukukhulelwa inyanga nenyanga ngexesha lonyango lwakho kunye neenyanga ezi-6 emva koko. Shayela ugqirha wakho ngokukhawuleza ukuba ukhulelwe ngeli xesha. I-Ribavirin inokubangela ukwenzakala okanye ukufa kwimveku engekazalwa.

Kwizigulana ezingamadoda:

Musa ukuthatha i-ribavirin ukuba iqabane lakho likhulelwe okanye liceba ukukhulelwa. Ukuba uneqabane elinokukhulelwa, akufuneki uqale ukuthatha i-ribavirin de uvavanyo lokukhulelwa lubonise ukuba akakhulelwanga. Kuya kufuneka usebenzise iindlela ezimbini zolawulo lokuzalwa, kubandakanya ikhondom ene-spermicide ngexesha lonyango lwakho kunye neenyanga ezi-6 emva koko. Iqabane lakho kufuneka livavanyelwe ukukhulelwa inyanga nenyanga ngeli xesha. Shayela ugqirha wakho ngokukhawuleza ukuba iqabane lakho likhulelwe. I-Ribavirin inokubangela ukwenzakala okanye ukufa kwimveku engekazalwa.

I-Ribavirin isetyenziselwa amayeza e-interferon anjenge peginterferon alfa-2a [Pegasys] okanye i-peginterferon alpha-2b [PEG-Intron]) ukunyanga i-hepatitis C kubantu abangazange banyangwe nge-interferon ngaphambili. I-Ribavirin ikwiklasi yamayeza antiviral abizwa ngokuba zii-nucleoside analogue. Isebenza ngokumisa intsholongwane ebangela i-hepatitis C ukuba isasazeke emzimbeni. Ayaziwa ukuba unyango olubandakanya i-ribavirin kunye nolunye unyango lunyanga usulelo lwe-hepatitis C, kuthintela ukonakala kwesibindi okunokubangelwa yi-hepatitis C, okanye kuthintele ukusasazeka kwe-hepatitis C kwabanye abantu.

I-Ribavirin iza njengecwecwe, njengephilisi kunye nesisombululo somlomo (ulwelo) ukuba sithathwe ngomlomo. Ihlala ithathwa ngokutya kabini ngemini, kusasa nangokuhlwa, kangangeeveki ezingama-24 ukuya kuma-48 okanye ngaphezulu. Thatha i-ribavirin ngamaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-ribavirin ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya zonke iifomsile; ungahluleli, ungahlaleli, okanye uzityumze.

Hlanganisa ulwelo kakuhle ngaphambi kokuba usebenzise nganye ukuxuba amayeza ngokulinganayo. Qiniseka ukuba uhlamba icephe lokulinganisa okanye ikomityi emva kokuyisebenzisa ngalo lonke ixesha ulinganisa ulwelo.

Ugqirha wakho angayinciphisa idosi okanye akuxelele ukuba uyeke ukuthatha i-ribavirin ukuba uvela kwiziphumo ebezingalindelekanga zonyango okanye ukuba iimvavanyo ezithile zaselebhu zibonisa ukuba imeko yakho ayiphucukanga. Tsalela ugqirha wakho ukuba ukhathazwa ziziphumo ebezingalindelekanga ze-ribavirin. Sukunciphisa idosi yakho okanye uyeke ukuthatha i-ribavirin ngaphandle kokuba ugqirha wakho ukuxelele ukuba kufanele.

I-Ribavirin ngamanye amaxesha isetyenziselwa ukunyanga imikhuhlane yentsholongwane (intsholongwane enokubangela ukopha ngaphakathi nangaphandle komzimba, iingxaki kumalungu amaninzi, kunye nokufa). Kwimeko yemfazwe yebhayoloji, i-ribavirin inokusetyenziselwa ukunyanga umkhuhlane wentsholongwane egazini osasazeke ngabom. I-Ribavirin ngamanye amaxesha isetyenziselwa ukunyanga isifo sokuphefumla esiqatha (SARS; intsholongwane enokubangela iingxaki zokuphefumla, inyumoniya kunye nokufa). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli chiza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-ribavirin,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-ribavirin, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-ribavirin, iifomsile, okanye isisombululo somlomo. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha i-didanosine (Videx). Ugqirha wakho uya kukuxelela ukuba ungathathi i-ribavirin ukuba uthatha eli yeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: azathioprine (Azasan, Imuran); amayeza oxinzelelo, uxinzelelo, okanye esinye isifo sengqondo; i-nucleoside reverse transcriptase inhibitors (i-NRTIs) yentsholongwane yomntu (i-HIV) okanye ifunyenwe isifo se-immunodeficiency syndrome (i-AIDS) efana ne-abacavir (iZiagen, e-Atripla, eTrizivir), emtricitabine (Emtriva, e-Atripla, eTruvada), lamivudine (Epivir, in in I-Combivir, kwi-Epzicom), i-stavudine (iZerit), i-tenofovir (i-Viread, e-Atripla, eTruvada), kunye ne-zidovudine (i-Retrovir, e-Combivir, e-Trizivir); kunye namayeza acinezela amajoni omzimba afana nomhlaza chemotherapy, cyclosporine (Neoral, Sandimmune), sirolimus (Rapamune), kunye ne tacrolimus (Prograf). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba unesifo sezintso, ukusilela kwesibindi, okanye isifo sokuqina komzimba (ukudumba kwesibindi okwenzeka xa amajoni omzimba ehlasela isibindi). Ugqirha wakho unokukuxelela ukuba ungathathi i-ribavirin.
• xelela ugqirha wakho ukuba uyasela okanye wakha wasela izixa ezikhulu zotywala, ukuba ukhe wasebenzisa okanye wakha wasebenzisa iziyobisi ezitalatweni, ukuba ukhe wacinga ngokuzibulala okanye ucebe okanye uzama ukwenza njalo, kwaye ukuba ukhe wafakelwa isibindi okanye olunye utyando Xelela ugqirha wakho ukuba ukhe okanye wakha wagula ngengqondo njengoxinzelelo, ixhala, okanye isifo sengqondo (ukulahleka konxibelelwano kunye nenyani); umhlaza; Intsholongwane kaGawulayo okanye uGawulayo; isifo seswekile; sarcoidosis (imeko apho izihlunu ezingaqhelekanga zikhula khona kwiindawo zomzimba ezinje ngemiphunga); Isifo sikaGilbert (imeko yesibindi ethambileyo enokubangela ukuba tyheli kolusu okanye kwamehlo); igawuthi (uhlobo lwesifo samathambo olubangelwa ziikristale ezibekwe kumalungu); naluphi na uhlobo lwesifo sesibindi ngaphandle kwe-hepatitis C; okanye i-thyroid, i-pancreas, iso, okanye isifo semiphunga.
• xelela ugqirha wakho ukuba uncelisa.
• Kuya kufuneka uyazi ukuba i-ribavirin inokukwenza wozele, ube nesiyezi, okanye udideke. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.
• ungaseli iziselo ezinxilisayo ngelixa uthatha i-ribavirin. Utywala bunokusenza mandundu isifo sakho sesibindi.
• Kuya kufuneka uyazi ukuba umlomo wakho unokuma kakhulu xa uthatha eli yeza, elinokukhokelela kwiingxaki ngamazinyo nasezintsinini. Qiniseka ukuba uhlamba amazinyo akho kabini ngemini kwaye uneemviwo eziqhelekileyo zamazinyo. Ukuba ukugabha kuyenzeka, hlamba umlomo wakho kakuhle.

Qiniseka ukuba usele amanzi amaninzi ngelixa uthatha i-ribavirin.

Ukuba ukhumbula idosi ephosiweyo kwangolo suku, thabatha amayeza kwangoko. Nangona kunjalo, ukuba awukhumbuli idosi ephosiweyo kude kube lusuku olulandelayo, tsalela ugqirha wakho ukuze ufumane ukuba wenzeni. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

IRibavirin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukukhohlela
• isisu esimoshakele
• ukugabha
• urhudo
• ukuqhina
• isilungulela
• Ukuphelelwa ngumdla wokutya
• ukuhla ukusinda
• utshintsho kubuchule bokungcamla ukutya
• umlomo owomileyo
• ubunzima bokugxila
• ubunzima bokulala okanye ukulala
• ukulahleka kwememori
• irhashalala
• owomileyo, ocatshukiswayo, okanye ulusu olurhawuzayo
• ukubila
• ukuba sexesheni okubuhlungu okanye okungaqhelekanga (ixesha)
• iintlungu zemisipha okanye zethambo
• ukulahleka kweenwele

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba ufumana enye yazo, okanye ezo zidweliswe kwicandelo LESILumkiso ESIBALULEKILEYO, tsalela ugqirha wakho ngokukhawuleza:

• urhwebo
• ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukudinwa
• ubunzima bokuginya okanye ukuphefumla
• iintlungu esiswini okanye kumqolo ongezantsi
• Urhudo olunegazi
• Igazi elibomvu elibomvu kwizitulo
• mnyama, ilindle
• ukudumba kwesisu
• ukudideka
• umchamo omnyama-mnyama
• mthubi ulusu okanye amehlo
• ukopha okungaqhelekanga okanye ukugruzuka
• utshintsho lombono
• umkhuhlane, ukugodola kunye neminye imiqondiso yosulelo
• ukudakumba
• ucinga ngokuzenzakalisa okanye ukuzibulala
• utshintsho lweemvakalelo
• ukukhathazeka ngokweqile
• ukucaphuka
• ukuqala ukusebenzisa iziyobisi zasesitalatweni okanye utywala kwakhona ukuba wawukhe wazisebenzisa ezi zinto ngaphambili
• ukunganyamezelani kubanda

I-Ribavirin inokunciphisa ukukhula kunye nokuzuza ubunzima kubantwana. Thetha nogqirha womntwana wakho malunga neengozi zokunika umntwana wakho eli yeza.

I-Ribavirin inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Gcina amacwecwe e-ribavirin kunye neephilisi kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Gcina isisombululo somlomo se-ribavirin kwifriji okanye kubushushu begumbi.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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