Isodium Oxybate

Umxholo

• Ukulungiselela iidosi ze-sodium oxybate, landela la manyathelo:
• Ngaphambi kokuba uthathe ioksybhdiyamu,
• Isodium oxybate inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba ufumana enye yazo okanye ezo zidweliswe kwicandelo LESILumkiso ESIBALULEKILEYO, tsalela ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

Isodium oxybate lelinye igama le-GHB, into edla ngokuthengiswa ngokungekho mthethweni kwaye iphathwe gadalala, ngakumbi ngabantu abadala abancinci kwiindawo zentlalo ezinje ngeeklabhu zasebusuku. Tshela ugqirha wakho ukuba usebenzisa okanye wakha wasebenzisa iziyobisi ezitalatweni, okanye ukuba uthe wawasebenzisa kakhulu amayeza kagqirha. Isoksibhodi yesodium inokuba yingozi xa ithathwa ngabantu ngaphandle komntu ebimiselwe yona. Musa ukuthengisa okanye unike ioksydbd sodium yakho komnye umntu; ukuthengisa okanye ukwabelana ngayo kuchasene nomthetho. Gcina umoya we-sodium kwindawo ekhuselekileyo, njengekhabhinethi okanye ibhokisi, ukuze kungabikho mntu unokuyithatha ngengozi okanye ngenjongo. Gcina umkhondo wokuba kungakanani ulwelo olushiyekileyo kwibhotile yakho ukuze wazi ukuba akukho nto ilahlekileyo.

Isodium oxybate inokubangela iziphumo ebezingalindelekanga ezimandundu, kubandakanya neengxaki zokuphefumla ezinobuzaza okanye ezinobungozi. Tshela ugqirha wakho ukuba uthatha iipilisi zokulala. Ugqirha wakho uya kukuxelela ukuba ungathathi i-oxybate ye-sodium ngelixa uthatha la mayeza. Kwakhona, xelela ugqirha wakho ukuba uthatha i-anti-depressants; benzodiazepines ezifana ne-alprazolam (Xanax), chlordiazepoxide (Librium), clonazepam (Klonopin), diazepam (Diastat, Valium), estazolam, flurazepam, lorazepam (Ativan), oxazepam, temazepam (Restoril), kunye ne triaz amayeza okugula ngengqondo, isicaphucaphu, okanye ukuxhuzula; izihlunu ezonwabisayo; okanye amayeza entlungu. Ugqirha wakho unokufuna ukutshintsha amayeza akho kunye nokubeka esweni ngononophelo. Musa ukusela iziselo ezinxilisayo ngelixa uthatha i-sodium oxybate.

Isodium oxybate ayifumaneki kwiivenkile ezithengisa iimpahla. Isodium oxybate ifumaneka kuphela ngenkqubo yokuhambisa ethintelweyo ebizwa ngokuba yiNkqubo yeXywav kunye neXyrem REMS. Yinkqubo ekhethekileyo yokuhambisa amayeza kunye nokubonelela ngolwazi malunga namayeza. Amayeza akho aya kuthunyelwa ngeposi usuka kwikhemesti esembindini emva kokuba ulifundile ulwazi kwaye wathetha nosokhemesti. Buza ugqirha wakho ukuba unemibuzo malunga nokuba uza kuwafumana njani amayeza akho.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-sodium oksijini kwaye ngalo lonke ixesha uzalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungasifumana isiKhokelo seMithi kwiwebhusayithi ye-FDA: http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm.

Gcina lonke ixesha lokudibana nogqirha wakho.

Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-sodium oxybate.

Isodium oxybate isetyenziselwa ukuthintela uhlaselo lwe cataplexy (iziqendu zobuthathaka bemisipha eziqala ngesiquphe kwaye zihlale okwexeshana) kunye nokulala kakhulu emini kubantu abadala nakubantwana abaneminyaka esi-7 ubudala nangaphezulu abane-narcolepsy (ingxaki yokulala enokubangela ukulala kakhulu , ngesiquphe esingalawulekiyo sokufuna ukulala ngexesha lemisebenzi yemihla ngemihla, kunye nekati (cataplexy).Isodium oxybate ikudidi lwamayeza ekuthiwa sisistim se-nervous system depressants. Isodium oxybate isebenza ukunyanga i-narcolepsy kunye ne-cataplexy ngokunciphisa umsebenzi kwingqondo.

Isodium oxybate iza njengesisombululo (ulwelo) ukuxubana namanzi kwaye uthathe ngomlomo. Ihlala ithathwa kabini ngobusuku ngabunye kuba ioksyidiyidi yesodium iyanxiba emva kwexesha elifutshane, kwaye iziphumo zedosi enye aziyi kuhlala ubusuku bonke. Idosi yokuqala ithathwa ngexesha lokulala, kwaye idosi yesibini ithathwa iiyure ezi-2/2 ukuya kwezi-4 emva kwethamo lokuqala. I-oxybate ye-sodium kufuneka ithathwe ngaphandle kwesisu, ngoko ke idosi yokuqala kufuneka ithathwe ubuncinci iiyure ezi-2 emva kokutya. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo.

Musa ukuthatha iidosi zakho zokulala ngexesha lokulala de ube wena okanye umntwana ulele kwaye ulungele ukulala ebusuku. Isodium oxybate iqala ukusebenza ngokukhawuleza, kwisithuba semizuzu emi-5 ukuya kweli-15 emva kokuyithatha. Beka idosi yakho yesibini yesodiyam yodisi kwindawo ekhuselekileyo kufutshane nebhedi yakho (okanye kwindawo ekhuselekileyo oza kuyinika umntwana wakho) ngaphambi kokuba ulale. Sebenzisa iwotshi yealam ukuba uqiniseke ukuba uya kuvuka ngexesha lokuthatha idosi yesibini. Ukuba wena okanye umntwana wakho uvuka ngaphambi kokuba ialam ikhale kwaye ubuncinci iiyure ezi-2/2 okoko uthathe idosi yakho yokuqala, thatha idosi yakho yesibini, ucime ialam, kwaye uphinde ulale.

Ugqirha wakho uya kukuqala ngedosi esezantsi ye-sodium oxybate kwaye ngokuthe chu ayonyuse idosi yakho, hayi rhoqo rhoqo kube kanye ngeveki.

Isodium oxybate inokuba sisiqhelo sokwenza. Sukuyithatha ngaphezulu okanye uyithathe rhoqo kunokuyalelwa ngugqirha. Ukuba uthatha i-oxybate enesodium eninzi, unokufumana iimpawu ezisongela ubomi kubandakanya ukubanjwa, ukuncipha okanye ukuyeka ukuphefumla, ukulahleka kwengqondo, kunye ne-coma. Unokuphinda uhlakulele umnqweno we-sodium oxybate, uzive unesidingo sokuthatha amanani amakhulu kunye namakhulu, okanye ufuna ukuqhubeka nokuthatha i-sodium oxybate nangona ibangela iimpawu ezingathandekiyo. Ukuba uthathe i-sodium oxybate ngezixa ezikhulu kunokuba umiselwe ngugqirha wakho, kwaye ngequbuliso uyeke ukuyithatha, unokufumana iimpawu zokurhoxa njengobunzima bokulala okanye ukulala, ukungazinzi, unxunguphalo, ukucinga ngokungaqhelekanga, ukuphulukana nokunxibelelana nenyani, ukulala , isisu esibuhlungu, ukungcangcazela kwilungu lomzimba ongakwaziyo ukulilawula, ukubila, ukuxilwa kwezihlunu nokubetha kwentliziyo okukhawulezayo.

Isodium oxybate inokunceda ukulawula iimpawu zakho kodwa ayizukuyinyanga imeko yakho. Qhubeka uthathe ioksyidiyamu yesodium nangona uziva uphilile. Ungayeki ukuthatha i-oxybate ye-sodium ngaphandle kokuthetha nogqirha wakho. Ugqirha wakho uya kufuna ukunciphisa umthamo wakho ngokuthe ngcembe. Ukuba ngequbuliso uyeka ukuthatha i-sodium oxybate, unokuba nokuhlaselwa ngakumbi kwe-cataplexy kwaye unokufumana uxinzelelo kunye nobunzima bokulala okanye ukulala.

Ukulungiselela iidosi ze-sodium oxybate, landela la manyathelo:

1. Vula ibhokisi engene iyeza lakho ususe ibhotile yeyeza kunye nesixhobo sokulinganisa.
2. Susa isixhobo sokulinganisa kwisisongeli sayo.
3. Vula ibhotile ngokutyhalela ezantsi kwikepusi kwaye ujike ikepusi ngokungqinelana newashi (ngasekhohlo) ngaxeshanye.
4. Beka ibhotile evulekileyo ithe nkqo phezu kwetafile.
5. Bamba ibhotile ime nkqo ngesandla esinye. Sebenzisa esinye isandla ukubeka incam yesixhobo sokulinganisa kwiziko lokuvula ngaphezulu kwebhotile. Cinezela incam ngokuqinileyo kuvulwe.
6. Bamba ibhotile kunye nesixhobo sokulinganisa ngesandla esinye. Sebenzisa esinye isandla ukubuyela kwiplunger de kube kukumakisha okuhambelana nethamo ugqirha wakho amiselweyo. Qiniseka ukuba ugcina ibhotile ethe nkqo ukuvumela iyeza ukuba ligele kwisixhobo sokulinganisa.
7. Susa isixhobo sokulinganisa ngaphezulu kwebhotile. Beka incam yesixhobo sokulinganisa kwenye yeekomityi zokulinganisa zinikwe amayeza.
8. Cinezela phantsi kwiplunger ukukhupha iyeza kwindebe ye-dosing.
9. Yongeza ii-ounces ezi-2 (i-60 milliliters, i-1/4 indebe, okanye malunga neepuni ezine) zamanzi ompompo kwindebe ye-dosing. Iyeza liya kungcamla ngcono xa uxube namanzi abandayo. Yenza hayi xuba iyeza kunye nejusi yeziqhamo, iziselo ezihlwahlwazayo, okanye naluphi na ulwelo.
10. Phinda kwakhona amanyathelo ama-5 ukuya kwele-9 ukulungiselela idosi yeoksijini yenyukliya kwikomityi yesibini yedosi.
11. Beka iminqwazi kuzo zombini iikomityi zokulinganisa. Jika ikepusi nganye ngokwewotshi (ngasekunene) ide icofe kwaye itshixe endaweni yayo.
12. Hlanganisa isixhobo sokulinganisa ngamanzi.
13. Buyisela ikepusi kwibhotile ye-sodium oxide kwaye ubuyisele ibhotile kunye nesixhobo sokulinganisa kwindawo ekhuselekileyo apho zigcinwe kude ebantwaneni nakwizilwanyana zasekhaya. Beka zombini iikomityi zedosi ezilungiselelwe kwindawo ekhuselekileyo kufutshane nebhedi yakho okanye kwindawo ekhuselekileyo yokunika umntwana wakho ukufikelela kubantwana nakwizilwanyana zasekhaya.
14. Xa ilixesha lokuba uthathe idosi yokuqala ye-sodium oxybate, cinezela ezantsi kwikepusi kwaye uyijike ngokuchaseneyo newashi (ngasekhohlo). Sela lonke ulwelo xa uhleli ebhedini yakho. Beka ikepusi emva kwindebe, uyijike ngokwewotshi (ngasekunene) ukuyitshixela endaweni yayo, kwaye ulale kwangoko.
15. Xa uvuka i-2/2 ukuya kwi-4 iiyure kamva ukuba uthathe idosi yesibini, phinda inyathelo le-14.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe ioksybhdiyamu,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba u-aleji kwi-sodium oxybate, naliphi na iyeza, okanye nasiphi na isithako kwisisombululo se-sodium oxybate. Buza usokhemesti wakho okanye ujonge isikhokelo sonyango kuluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo. Qiniseka ukuba ukhankanya oku kulandelayo: divalproex (Depakote). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wakha wanesiphene se-semialdehyde dehydrogenase (imeko ezuzwe njengelifa apho izinto ezithile zakha emzimbeni kwaye zibangela ukudodobala kunye nokulibaziseka kophuhliso). Ugqirha wakho uya kukuxelela ukuba ungathathi i-oxybate ye-sodium.
• xelela ugqirha wakho ukuba ulandela ukutya okunetyuwa encinci ngenxa yezizathu zonyango. Xelela ugqirha wakho ukuba uyarhona; ukuba ukhe wacinga ngokuzenzakalisa okanye ukuzibulala okanye ucebe okanye uzame ukwenza njalo; kwaye ukuba unesifo semiphunga, okanye ukuphefumla nzima, ukuphefumla ubuthongo (ingxaki yokulala ebangela ukuphefumla kuyeke okwexeshana xa ulele), ukuxhuzula, ukudakumba okanye esinye isifo sengqondo, ukusilela kwentliziyo, uxinzelelo lwegazi oluphezulu, okanye isibindi okanye isifo sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-sodium oxybate, biza ugqirha wakho.
• ukuba uyenziwa uqhaqho, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha ioksybhate yesodiyam.
• Kuya kufuneka uyazi ukuba uya kulala kakhulu ubuncinci iiyure ezingama-6 emva kokuba uthathe ioksiyiti yomoya, kwaye usenokozela nasemini. Ungaqhubi ngemoto, usebenzise oomatshini, uhambe ngenqwelomoya, okanye wenze nayiphi na into eyingozi ubuncinci iiyure ze-6 emva kokuba uthathe amayeza akho. Kuphephe ukwenza imisebenzi eyingozi ngalo lonke ixesha de ube uyazi ukuba ifuthe le-sodium oxybate likuchaphazela njani.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba uyaphoswa yidosi yesibini ye-sodium oxybate, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethosi rhoqo ngobusuku obulandelayo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo. Njalo vumela ubuncinci iiyure ezingama-2/2 phakathi kwamayeza e-oxybate yesodium.

Isodium oxybate inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukufuma ebhedini
• intloko ebuhlungu
• isiyezi
• ndiziva ndinxilile
• ukungcangcazela kwelungu lomzimba ongenakulilawula
• iimvakalelo zokuba ndindisholo, ukurhawuzelela, ukuhlaba, ukutshisa, okanye ukukhasa esikhumbeni
• ubunzima bokuhamba xa ulele okanye uvuka
• isicaphucaphu
• ukugabha
• urhudo
• isisu esibuhlungu
• umqolo obuhlungu
• ubuthathaka
• ukudumba kweengalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukubila

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba ufumana enye yazo okanye ezo zidweliswe kwicandelo LESILumkiso ESIBALULEKILEYO, tsalela ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ukulala
• amaphupha angaqhelekanga
• ukuphazamiseka
• Ubundlongondlongo
• ixhala
• ukudakumba
• ukudideka okanye iingxaki zememori
• utshintsho kubunzima okanye ukutya
• ukuziva unetyala
• iingcinga zokuzenzakalisa okanye ukuzibulala
• Ndiva ukuba abanye bafuna ukukwenzakalisa
• ukubona izinto ezingekhoyo (ukubona izinto okanye ukuva amazwi angabikho)
• ukuphulukana nokunxibelelana nenyani
• iingxaki zokuphefumla, ukurhona, okanye ubuthongo bokulala
• ukozela kakhulu emini

Isodium oxybate inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni nakwizilwanyana zasekhaya. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Thela nawaphi na amayeza aseleyo phantsi kwesinki ukuba ngaphezulu kweeyure ezingama-24 emva kokulungiswa. Nqamleza ileyibhile kwibhotile enesiphawuli uze uyilahle kwibhotile engenanto emgqomeni. Buza ugqirha wakho okanye utsalele ikhemesti esembindini ukuba unemibuzo malunga nokuchithwa okufanelekileyo kwamayeza akho ukuba aphelelwe lixesha okanye awasafuneki.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Iimpawu libanda kungaquka oku kulandelayo:

• ukudideka
• iingxaki ngokulungelelanisa
• ukuphazamiseka
• ukulahleka kwengqondo
• ikhoma
• ukuphefumla kancinci, kancinci, okanye okuphazamisayo
• ukulahleka kolawulo lwesinyi
• ukuphulukana nolawulo lwamathumbu
• ukugabha
• ukubila
• intloko ebuhlungu
• ukungaboni kakuhle
• izihlunu zemithambo okanye ukujija
• ukuxhuzula
• ukubetha kwentliziyo kancinci
• ubushushu bomzimba obuphantsi
• izihlunu ezibuthathaka

Buza ugqirha wakho okanye utsalele ikhemesti esembindini ukuba unayo nayiphi na imibuzo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Xyrem^®

• Isiseko seGamma Hydroxybutyrate
• GBH Isodium
• Isodium yeGHB
• I-Oxybate Sodium