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Umxholo

• Ukuthatha iipilisi ze-deferasirox zokumiswa (Exjade), landela la manyathelo:
• Ngaphambi kokuba uthathe i-deferasirox,
• I-Deferasirox inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zikhankanywe kwicandelo LESILUMKISO ESIBALULEKILEYO, tsalela ugqirha wakho ngokukhawuleza:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Deferasirox inokubangela umonakalo omkhulu okanye osongela ubomi kwizintso. Umngcipheko wokuba uza kukhula ngumonakalo wezintso mkhulu xa uneemeko ezininzi zonyango, okanye ugula kakhulu ngenxa yesifo segazi. Xelela ugqirha wakho ukuba ukhe unesifo sezintso. Ugqirha wakho unokukuxelela ukuba ungathathi i-deferasirox. Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba ugqirha kwangoko: ukuncipha kokuchama, ukudumba emaqatheni, imilenze, okanye iinyawo, ukudinwa kakhulu, ukuphefumla kancinci kunye nokudideka. Kubantwana abathatha la mayeza, kukho umngcipheko owandayo wokuba uya kuba neengxaki zezintso ukuba uyagula ngelixa uthatha i-deferasirox kwaye uphuhlise urhudo, ukugabha, umkhuhlane, okanye uyeke ukusela ulwelo ngokwesiqhelo. Shayela ugqirha wakho ngokukhawuleza ukuba unayo nayiphi na le mpawu.

I-Deferasirox inokubangela nomonakalo omkhulu okanye osongela ubomi kwisibindi. Umngcipheko wokuba uza kukhula umonakalo wesibindi mkhulu ukuba uneminyaka engaphezu kwe-55 ubudala, okanye ukuba unezinye iimeko ezinzima zonyango. Xelela ugqirha wakho ukuba ukhe unesifo sesibindi. Ukuba uvelisa naziphi na kwezi mpawu zilandelayo, biza ugqirha wakho kwangoko: ukutyheli kwesikhumba okanye amehlo, iimpawu ezinje ngomkhuhlane, ukungabikho kwamandla, ukungabi namdla, iintlungu kwinxalenye ephezulu yesisu, okanye ukugruzuka okanye ukopha okungaqhelekanga.

I-Deferasirox inokubangela ukopha okanye ukusongela ubomi ukopha esiswini okanye emathunjini. Umngcipheko wokuba uza kuphuma ukopha kakhulu esiswini okanye emathunjini unokuba mkhulu ukuba ukhulile, okanye ugula kakhulu kwimeko yegazi. Tshela ugqirha wakho ukuba unazo okanye ukhe waba nenqanaba eliphantsi leeplatelets (uhlobo lweseli yegazi olufunekayo ukulawula ukopha), okanye ukuba uthatha naliphi na kula mayeza alandelayo: , EJantoven); i-aspirin okanye ezinye iyeza ezichasayo (i-NSAIDs) ezinje nge-ibuprofen (Advil, Motrin, abanye) kunye ne-naproxen (Aleve, Naprosyn, abanye); amayeza athile okomeleza amathambo kubandakanya i-alendronate (Binosto, Fosamax), etidronate, ibandronate (Boniva), pamidronate, risedronate (Actonel, Atelvia), kunye ne-zoledronic acid (Reclast, Zometa); okanye ii-steroids ezinje nge-dexamethasone, methylprednisolone (A-methapred, Depo-medrol, Medrol, Solu-medrol), okanye prednisone (Rayos). Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: ukutshisa iintlungu zesisu, ukugabha okubomvu ngokuqaqambileyo okanye okukhangeleka ngathi yindawo yekhofi, igazi elibomvu eliqaqambileyo kwizitulo, okanye isitulo esimnyama okanye sokulinda.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya ku-odola uvavanyo lwelabhoratri ngaphambi kwaye ngexesha lonyango lwakho ukuze uqiniseke ukuba kukhuselekile kuwe ukuba uthathe i-deferasirox kwaye ubone ukuba uyayiphuhlisa na le miphumo mibi.

I-Deferasirox isetyenziselwa ukunyanga abantu abadala kunye nabantwana abaneminyaka emi-2 ubudala nangaphezulu abane-iron eninzi kakhulu emzimbeni wabo ngenxa yokuba batofelwe igazi elininzi. Isetyenziselwa ukunyanga abantu abadala kunye nabantwana abaneminyaka eli-10 ubudala nangaphezulu abane-iron eninzi emzimbeni wabo ngenxa yesifo segazi esibizwa ngokuba yi-thalassemia engaxhomekekanga kutofelo-gazi (NTDT). UDefferasirox ukwiklasi yamayeza abizwa ngokuba zi-iron chelators. Isebenza ngokudibanisa i-iron emzimbeni ukuze ikwazi ukuphuma (isuswe emzimbeni) kwilindle.

I-Deferasirox iza njengecwecwe, igranules kunye nethebhulethi yokumiswa (ithebhulethi inyibilike kulwelo) ukuyithatha ngomlomo. Imelwe ukuthathwa isisu esingenanto kanye ngemini, ubuncinci imizuzu engama-30 ngaphambi kokutya, Amacwecwe kunye negranules zinokuthathwa ngesidlo esilula esifana nengqolowa yesiNgesi epheleleyo enejeli kunye nobisi olunamafutha, okanye isandwich encinci isonka sengqolowa. Thatha i-deferasirox malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-deferasirox ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Iimveliso ezahlukeneyo ze-deferasirox zifunxwa ngumzimba ngeendlela ezahlukeneyo kwaye azinakutshintshwa enye nenye. Ukuba ufuna ukutshintshela kwenye imveliso ye-deferasirox uye kwenye, ugqirha wakho unokufuna ukulungelelanisa idosi yakho. Ngalo lonke ixesha ufumana amayeza akho, jonga ukuba uqinisekile ukuba uyifumene imveliso ye-deferasirox ebimiselwe wena. Buza usokhemesti wakho ukuba awuqinisekanga ukuba ufumene amayeza afanelekileyo.

Swallow deferasirox tablets (Jadenu) ngamanzi okanye ngolunye ulwelo. Ukuba unengxaki yokuginya ithebhulethi, unokuyityumza ithebhulethi kwaye udibanise nokutya okuthambileyo okufana neyogathi okanye iapilesauce kwangoko ngaphambi kokuyithatha. Nangona kunjalo, musa ukutyumza i-90 mg yecwecwe (iJadenu) usebenzisa isixhobo esiqhekezayo esinemiphetho edibeneyo.

Ukuthatha i-deferasirox granules (Jadenu), ufefe igranules kukutya okuthambileyo okunje ngeyogathi okanye iapilesauce kwangoko ngaphambi kokuyithatha.

Ukuthatha iipilisi ze-deferasirox zokumiswa (Exjade), landela la manyathelo:

1. Soloko unyibilikisa iipilisi zokumiswa kulwelo ngaphambi kokuba uzithathe. Musa ukuhlafuna okanye uginye iipilisi zokumiswa ngokupheleleyo.
2. Ukuba uthatha ngaphantsi kwe-1000 mg ye-deferasirox, gcwalisa ikomityi esecaleni (malunga ne-3.5 oz / 100 ml) ngamanzi, ijusi yeapile, okanye ijusi yeorenji. Ukuba uthatha ngaphezulu kwe-1000 mg ye-deferasirox, gcwalisa ikomityi (malunga ne-7 oz / 200 ml) ngamanzi, ijusi yeapile, okanye ijusi yeorenji. Ukuba awuqinisekanga ukuba uza kuthatha malini i-deferasirox, buza ugqirha wakho okanye usokhemesti.
3. Beka inani lamacwecwe ugqirha akuyalele ukuba uthathe kwindebe.
4. Gquba ulwelo imizuzu emi-3 ukuba unyibilikise ngokupheleleyo amacwecwe Umxube unokuba mkhulu njengoko ushukumisa.
5. Sela ulwelo ngoko nangoko.
6. Yongeza inani elincinci lolwelo kwikomityi engenanto kwaye uvuselele. Swayipha ikomityi yokunyibilikisa naliphi na iyeza elisekhona kwiglasi okanye kumvuseleli.
7. Sela okuseleyo kulwelo.

Ugqirha wakho unokuhlengahlengisa idosi yakho ye-deferasirox hayi ngaphezulu kwe kanye kwiinyanga ezi-3 ukuya kwezi-6, kuxhomekeke kwiziphumo zovavanyo lwakho lwelabhoratri.

I-Deferasirox isusa i-iron eyongezelelweyo emzimbeni wakho kancinci ngokuhamba kwexesha. Qhubeka nokuthatha i-deferasirox nokuba uziva uphilile. Sukuyeka ukuthatha i-deferasirox ungakhange uthethe nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-deferasirox,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-deferasirox, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-deferasirox, iigranu, okanye iipilisi zokumiswa. Buza ugqirha wakho okanye usokhemesti uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ngokukhankanya amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO kunye nayo nayiphi na kwezi zilandelayo: alosetron (Lotronex), aprepitant (Cinvanti, Emend), budesonide (Entocort, Pulmicort, Uceris, e Symbicort), buspirone, cholestyramine (Prevalite), colesevelam (Welchol), colestipol (Colestid), conivaptan (Vaprisol), cyclosporine (Gengraf, Neoral, Sandimmune), darifenacin (Enablex), darunavir (Prezista, e Prezcobix), dasatinib (Sprycel), dihydroergotamine (DHE 45, Migranalone (Multaq), duloxetine (Cymbalta), eletriptan (Relpax), eplerenone (Inspra), ergotamine (Ergomar, eCafergot, Migergot), everolimus (Afinitor, Zortress), felodipine, fentanyl (Actiq, Duragesic, Subsysic, (Arnuity Ellipta, Flovent, eBreo Ellipta, Advair), izinto zokuthintela ukukhawula iihomoni (iipilisi zolawulo lokuzalwa, iipatches, iiringi, okanye inaliti), indinavir (Crixivan), lopinavir (eKaletra), lovastatin (Altoprev), lurasidone (Latuda), maravirococ (I-Selzentry), midazolam, nisoldipine (Sular), paclitax el (Abraxane, Taxol), phenytoin (Dilantin, Phenytek), phenobarbital, pimozide (Orap), quetiapine (Seroquel), quinidine (eNuedexta), ramelteon (Rozerem), repaglinide (Prandin, e Prandimet), rifampin Radim , eRifamate, eRifater), ritonavir (Norvir, eKaletra, Technivie, Viekira Pak), saquinavir (Invirase), sildenafil (Revatio, Viagra), simvastatin (Flolopid, Zocor, eVytorin), siroliumus (Rapamuneus), tacrol Astagraf, Envarsus, Prograf), theophylline (Theo-24), ticagrelor (Brilinta), tipranavir (Aptivus), tizanidine (Zanaflex), triazolam (Halcion), tolvaptan (Samsca), kunye vardenafil (Levitra, Staxyn). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• ukuba uthatha ii-antacids ezine-aluminium ezinje nge-Amphojel, Alternagel, Gaviscon, Maalox, okanye Mylanta, zithathe iiyure ezi-2 ngaphambi okanye emva kwe-deferasirox.
• xelela ugqirha wakho ukuba uthini malunga neemveliso ezithengayo, ngakumbi i-melatonin, okanye ii-caffeine supplements.
• xelela ugqirha wakho ukuba une-myelodysplastic syndrome (ingxaki enzima ngomongo wethambo onomngcipheko omkhulu wokuba ngumhlaza), okanye umhlaza. Ugqirha wakho unokukuxelela ukuba ungathathi i-deferasirox.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-deferasirox, tsalela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo kamva emini, ubuncinci iiyure ze-2 emva kwesidlo sakho sokugqibela kunye nemizuzu engama-30 ngaphambi kokutya. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo okanye ukuba awuyi kuba nakho ukuthatha i-deferasirox kwisisu esingenanto, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Deferasirox inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isisu esibuhlungu
• isicaphucaphu
• ukugabha
• urhudo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zikhankanywe kwicandelo LESILUMKISO ESIBALULEKILEYO, tsalela ugqirha wakho ngokukhawuleza:

• ukulahlekelwa kwindlebe
• iingxaki zombono
• irhashalala, umngxunya, isikhumba esixobukayo okanye isikhumba esidumbileyo, umkhuhlane, i-lymph nodes
• ubunzima bokuphefumla okanye ukugwinya; ukudumba kobuso, umqala, ulwimi, imilebe, okanye amehlo; ukudinwa
• ukugruzuka okanye ukopha okungaqhelekanga

I-Deferasirox inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• mthubi ulusu okanye amehlo
• iintlungu kwinxalenye ephezulu yesisu
• ukugruzuka okanye ukopha okungaqhelekanga
• ukunqongophala kwamandla
• Ukuphelelwa ngumdla wokutya
• Iimpawu ezinjengomkhuhlane
• urhudo
• isicaphucaphu
• ukugabha
• ukuncipha kokuchama
• ukudumba kwemilenze okanye amaqatha

Gcina lonke ixesha lokudibana nogqirha wakho. Kuya kufuneka ukuba ube kuva iimviwo kunye nokuhlolwa kwamehlo ngaphambi kokuqala i-deferasirox kwaye kube kanye ngonyaka ngelixa uthatha eli yeza.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Ukuphuma^®
• Jadenu^®