Itretinoin

Umxholo

• Ngaphambi kokuba uthathe i-tretinoin,
• I-Tretinoin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

I-Tretinoin inokubangela iziphumo ebezingalindelekanga ezibi. I-Tretinoin kufuneka inikwe kuphela phantsi kweliso likagqirha onamava ekunyangeni abantu abane-leukemia (umhlaza weeseli ezimhlophe zegazi) nasesibhedlele apho izigulana zinokuthi zijongwe khona ngenxa yeziphumo ebezingalindelekanga kwaye zinyangwe ukuba ngaba iziphumo ebezingalindelekanga zenzeka.

I-Tretinoin inokubangela iqela elinobuzaza okanye elisongela ubomi leempawu ezibizwa ngokuba yi-retinoic acid-APL (RA-APL) syndrome. Ugqirha wakho uya kukujonga ngononophelo ukuze abone ukuba uyayiphuhlisa na le syndrome. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, biza ugqirha ngoko nangoko: umkhuhlane; ukutyeba kwakho; ukudumba kweengalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi; ukuqhawukelwa ngumphefumlo; ukuphefumla nzima; ukuvutha; iintlungu zesifuba; okanye ukukhohlela. Kwimpawu zokuqala zokuba uphuhlisa isifo se-RA-APL, ugqirha wakho uya kukuyalela iyeza elinye okanye nangaphezulu ukunyanga isifo.

I-Tretinoin inokubangela ukonyuka ngokukhawuleza kwenani leeseli ezimhlophe emzimbeni. Oku kunxulunyaniswa nomngcipheko ophezulu weziphumo ebezisongela ubomi. Ukuba unenani eliphezulu kakhulu leeseli ezimhlophe zegazi ngaphambi kokuba uqale unyango lwe-tretinoin, okanye ukuba unokonyuka kwenani leeseli ezimhlophe ngexesha lonyango lwakho nge-tretinoin, ingakumbi ukuba ufumana naziphi na iimpawu zesifo se-RA-APL, ugqirha wakho unokumisela iyeza elinye okanye nangaphezulu ukunyanga okanye ukuthintela ukwanda kweeseli ezimhlophe zegazi.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwi-tretinoin.

Thetha nogqirha wakho malunga nomngcipheko (s) wokuthatha i-tretinoin.

Kwabaguli ababhinqileyo:

I-Tretinoin akufuneki ithathwe zizigulana ezikhulelweyo okanye ezinokukhulelwa. Kukho umngcipheko omkhulu wokuba i-tretinoin ibangele ukuba umntwana azalwe enesiphene sokuzalwa (iingxaki zomzimba ezikhoyo ekuzalweni).

Ukuba unokukhulelwa, kuya kufuneka unqande ukukhulelwa ngexesha lonyango lwakho kunye ne-tretinoin. Kuya kufuneka usebenzise iindlela ezimbini ezamkelekileyo zolawulo lokuzalwa ngexesha lonyango lwakho kunye nenyanga e-1 emva konyango lwakho, nokuba ungachumanga (kunzima ukukhulelwa) okanye unamava okuyeka ukuya exesheni ('utshintsho lobomi'; ukuphela kwexesha lokuya exesheni ngenyanga).Kuya kufuneka usebenzise ezi ndlela zimbini zokuthintela inzala ngalo lonke ixesha ngaphandle kokuba ungathembisa ukuba awuyi kuba nakubonana ngesondo nendoda kangangenyanga enye emva konyango lwakho. Ugqirha wakho uza kukuxelela ukuba zeziphi iintlobo zolawulo lokuzalwa ezamkelekileyo, kwaye uya kukunika ulwazi olupheleleyo malunga nolawulo lokuzalwa.

Ukuba ucwangcisa ukusebenzisa izinto zokucwangcisa ngomlomo (iipilisi zolawulo lokuzalwa) ngelixa uthatha i-tretinoin, xelela ugqirha wakho igama lepilisi oza kuyisebenzisa. Iprogestin encinci ('minipill') yokuthintela inzala ngomlomo (Ovrette, Micronor, Nor-D) isenokungabi yindlela esebenzayo yolawulo lokuzalwa kwabantu abathatha i-tretinoin.

Kufuneka ube novavanyo lokukhulelwa olungelulo kwiveki e-1 ngaphambi kokuba uqale ukuthatha i-tretinoin. Kuya kufuneka ukuba uvavanywe ukukhulelwa elebhu inyanga nenyanga ngexesha lonyango lwakho. Tshela ugqirha wakho ngokukhawuleza ukuba ucinga ukuba unokukhulelwa nanini na ngexesha lonyango lwakho kunye ne-tretinoin.

I-Tretinoin isetyenziselwa ukunyanga i-leukemia ye-promyelocytic etsolo (i-APL; uhlobo lomhlaza apho zininzi kakhulu iiseli zegazi ezingafakwanga egazini kunye nomongo wethambo) kubantu abangakhange bancedwe zezinye iintlobo zekhemotherapy okanye imeko yabo ephucukileyo kodwa emva koko kubi ngokulandela unyango nezinye iintlobo zekhemotherapy. I-Tretinoin isetyenziselwa ukuvelisa ukuxolelwa (ukwehla okanye ukunyamalala kweempawu zomhlaza) we-APL, kodwa amanye amayeza kufuneka asetyenziswe emva konyango kunye ne-tretinoin ukukhusela umhlaza ekubuyeni. I-Tretinoin ikudidi lwamayeza abizwa ngokuba yi-retinoids. Isebenza ngokunciphisa okanye ukuyeka ukukhula kweeseli zomhlaza ngokubangela ukuba iiseli zegazi ezingafakwanga zikhule zibe ziiseli zegazi eziqhelekileyo.

I-Tretinoin iza njengecapsule ukuthatha ngomlomo. Ihlala ithathwa kabini ngemini ukuya kwiintsuku ezingama-90. Thatha i-tretinoin ngeenxa zonke ngamaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-tretinoin ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Qhubeka uthatha i-tretinoin nokuba uziva uphilile. Ungayeki ukuthatha i-tretinoin ngaphandle kokuthetha nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-tretinoin,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-tretinoin, ezinye i-retinoids ezifana ne-acitretin (Soriatane), etretinate (Tegison), bexarotene, okanye isotretinoin (Accutane, Claravis, Sotret), nawaphi na amanye amayeza, i-parabens (i-preservative), okanye nayiphi na into zezinye izithako kwiifomsile ze-tretinoin. Buza ugqirha wakho okanye usokhemesti uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: aminocaproic acid (Amicar); iibhlokhi ezithile zekhalsiyam ezinje nge-diltiazem (Cardizem, Dilacor, Tiazac, ezinye) kunye ne-verapamil (Calan, Covera, Isoptin, Verelan); cimetidine (iTagamet); i-cyclosporine (iSandimmune, iGengraf, iNeoral); i-erythromycin (i-EES, i-Erythrocin, i-E-Mycin); ihydroxyurea (iDroxia); ketoconazole (Nizoral); pentobarbital; phenobarbital; i-rifampin (iRifadin, iRimactane); i-steroids yomlomo efana ne-dexamethasone (i-Decadron, i-Dexone), i-methylprednisolone (iMedrol), kunye ne-prednisone (iDeltasone); tetracycline antibiotics ezifana ne-demeclocycline (Declomycin), doxycycline (Monodox, Vibramycin, abanye), minocycline (Minocin), oxytetracycline (Terramycin), kunye ne-tetracycline (Sumycin, Tetrex, abanye); i-tranexamic acid (iCyklokapron); kunye novithamini A. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akuqwalasele ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-tretinoin, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba ukhe wakhula okanye wakha ukwanda kwecholesterol (into efana namanqatha) kunye nezinye izinto ezinamanqatha egazini, okanye isibindi okanye isifo sentliziyo.
• xelela ugqirha wakho ukuba uncelisa.
• ukuba uza kutyandwa, kubandakanya utyando lwamazinyo, xelela ugqirha wakho okanye ugqirha wamazinyo ukuba uthatha i-tretinoin.
• Kuya kufuneka uyazi ukuba i-tretinoin inokubangela ukuba nesiyezi okanye intloko ebuhlungu. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi ukuba lonyango lukuchaphazela njani.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yegrapefruit ngelixa uthatha eli yeza.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Tretinoin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ubuthathaka
• ukudinwa kakhulu
• ndingcangcazela
• intlungu
• indlebe
• imvakalelo yokugcwala ezindlebeni
• isikhumba esomileyo
• irhashalala
• ukulahleka kweenwele
• ukuqhina
• urhudo
• isisu esibuhlungu
• isilungulela
• Ukuphelelwa ngumdla wokutya
• ukuhla ukusinda
• iintlungu zethambo
• isiyezi
• ukuba ndindisholo, ukutshisa, okanye ukubetha ezandleni okanye ezinyaweni
• uvalo
• ukudakumba
• ubunzima bokulala okanye ukulala
• ukudideka
• ukuphazamiseka
• i-hallucinating (ukubona izinto okanye ukuva amazwi angabikho)
• ubunzima bokuchama
• ukugungxula

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

• intloko ebuhlungu
• isicaphucaphu
• ukugabha
• ukungaboni kakuhle okanye umbono ophindwe kabini, okanye ezinye iingxaki zombono
• ukugruzuka okanye ukopha okungaqhelekanga
• ukugabha okunegazi okanye okujongeka njengendawo yekofu
• umbala obomvu ogqamileyo okanye omnyama kunye nezitulo ezilindileyo
• ukubetha kwentliziyo ngokungaqhelekanga
• ukulahlekelwa kwindlebe
• ukopha
• usulelo

I-Tretinoin inokunyusa amanqanaba e-cholesterol kunye namanye amafutha egazini lakho kwaye inokumisa isibindi sakho ekusebenzeni ngesiqhelo. Ugqirha wakho uya kukujonga ngononophelo ukuze ubone ukuba ngaba ufumana ezinye zeempembelelo.

I-Tretinoin inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• intloko ebuhlungu
• ukugungxula
• obomvu, oqhekekileyo, kunye nemilebe ebuhlungu
• isisu esibuhlungu
• isiyezi
• ukulahleka koququzelelo

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho ukuba unemibuzo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Vesanoid^®