Inaliti yeUstekinumab

Umxholo

• Phambi kokufumana inaliti ustekinumab,
• Inaliti yeUstekinumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu okanye ezo zidweliswe kwiCandelo LOKUKHUSELEKILEYO, Biza ugqirha ngoko nangoko:

Inaliti ye-Ustekinumab isetyenziselwa ukunyanga i-plaque psoriasis (isifo solusu apho umbala obomvu, onamaxolo wenza iindawo ezithile zomzimba) kubantu abadala nakubantwana abaneminyaka emi-6 nangaphezulu abanokuxhamla kumayeza okanye kwi-phototherapy (unyango olubandakanya ukuveza ulusu ekukhanyeni kwe-ultraviolet). Isetyenziswa sodwa okanye ngokudibeneyo ne-methotrexate (Otrexup, Rasuvo, Trexall) ukunyanga i-psoriatic arthritis (imeko ebangela iintlungu ezidibeneyo kunye nokudumba kunye nezikali kulusu) kubantu abadala. Inaliti yeUstekinumab ikwasetyenziselwa ukunyanga isifo sikaCrohn (imeko apho umzimba uhlasela ulwelwesi lwendlela yokugaya, ebangela iintlungu, urhudo, ukwehla kobunzima, kunye nefiva) kubantu abadala. Inaliti yeUstekinumab ikwasetyenziselwa ukunyanga ulcerative colitis (imeko ebangela ukudumba kunye nezilonda kumngxunya wekholoni [amathumbu amakhulu] kunye ne-rectum) kubantu abadala. Inaliti ye-Ustekinumab ikwiklasi yamayeza abizwa ngokuba ngamachiza omzimba. Isebenza ngokumisa isenzo seeseli ezithile emzimbeni ezibangela iimpawu ze-plaque psoriasis, i-psoriatic arthritis, isifo sikaCrohn, kunye ne-ulcerative colitis.

I-Ustekinumab iza njengesisombululo (ulwelo) ukujova (ngaphantsi kolusu) okanye ngaphakathi ngaphakathi (emthanjeni). Ukunyanga i-plaque psoriasis kunye ne-psoriatic arthritis, kuhlala kutofwa ngaphantsi kweeveki ezi-4 kwiidosi ezimbini zokuqala emva koko emva kweeveki ezili-12 ukuba unyango luyaqhubeka. Unyango lwesifo sikaCrohn kunye nesilonda esibuhlungu sokudumba okwenziwa sisilonda sikabhobhosi, sihlala sitofelwe ngenaliti ngenaliti kwidosi yokuqala size sinikezwe ngendlela engaphantsi kwisithuba seeveki ezisi-8 ngalo lonke ixesha unyango lusaqhubeka.

Uya kufumana idosi yakho yokuqala engaphantsi kwesitofu se-ustekinumab inaliti kwiofisi kagqirha wakho. Emva koko, ugqirha wakho unokuqhubeka nokukunika inaliti okanye akuvumele ukuba utofa inaliti ye-ustekinumab ngokwakho okanye ukhathalelwe ngumntu oza kwenza inaliti. Buza ugqirha wakho okanye usokhemesti akubonise okanye umntu oza kwenza inaliti ukuba utofa njani ustekinumab. Ngaphambi kokuba usebenzise inaliti ye-ustekinumab ngokwakho okokuqala, funda imiyalelo ebhaliweyo eza nayo.

Ukuba amayeza akho angena kwisirinji okanye igutyana oyikhethileyo, sebenzisa isirinji nganye okanye igutyana kube kanye kwaye utofe isisombululo kwisirinji. Nokuba kusekho isisombululo esisele kwisirinji okanye isixhobo, musa ukusisebenzisa kwakhona. Lahla iinaliti ezisetyenzisiweyo, iisirinji kunye nezixhobo kwisitya esinganyangekiyo. Thetha nogqirha wakho okanye usokhemesti malunga nokusilahla isikhongozeli esinganyangekiyo.

Musa ukushukumisa isirinji okanye igutyana ekhethiweyo equlethe ustekinumab.

Soloko ujonga isisombululo se-ustekinumab ngaphambi kokuyifaka. Jonga ukuba umhla wokuphelelwa awukadluli na kwaye ukuba ulwelo lucacile na okanye lutyheli kancinane. Umbane unokuqulatha amasuntswana amhlophe abonakalayo ambalwa. Sukusebenzisa ibhotile okanye isirinji ekhethiweyo ukuba yonakele, iphelelwe lixesha, iqabile, okanye ukuba ulwelo luguqulile okanye luqulathe amasuntswana amakhulu.

Ungayifaka inaliti ye-ustekinumab ngokufihlakeleyo naphi na ngaphambili kwethanga lakho (umlenze ongasentla), iingalo ezingaphezulu, iimpundu, okanye isisu (isisu) ngaphandle kwenkaba yakho kunye nommandla weesentimitha ezi-5 ngeenxa zonke. Ukunciphisa amathuba okuqaqamba okanye ububomvu, sebenzisa indawo eyahlukileyo yenaliti nganye. Musa ukujova kwindawo apho ulusu luthambile, lutyumkileyo, lubomvu, okanye lukhuni okanye apho uneziva okanye ukolula amanqaku.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lomguli lomenzi (Isikhokelo seMithi) xa uqala unyango ngenaliti ye-ustekinumab. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Phambi kokufumana inaliti ustekinumab,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-ustekinumab, nawaphi na amanye amayeza, okanye nasiphi na isithako se-ustekinumab injection. Ukuba uza kusebenzisa isirinji ekhethiweyo, xelela ugqirha wakho ukuba wena okanye umntu oza kutofa iyeza onokuthi uxabane nelatex okanye irabha. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya oku kulandelayo: , Rasuvo, Trexall, Xatmep), sirolimus (Rapamune), kunye netacrolimus (Astagraf, Envarsus, Prograf); okanye ii-steroids zomlomo ezifana ne-dexamethasone (Hemady), i-methylprednisolone (Medrol), kunye ne-prednisone (iRayos). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba wakhe wanalo naluphi na uhlobo lomhlaza. Xelela ugqirha wakho ukuba ufumene okanye ufumana i-phototherapy okanye i-allergies shots (uthotho lweenaliti ezinikwa rhoqo ukukhusela umzimba ekuphuhliseni ukungahambelani nezinto ezithile).
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa ufumana inaliti ye-ustekinumab, tsalela ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba usebenzisa inaliti ustekinumab.
• jongana nogqirha wakho ukubona ukuba ufuna ukufumana naluphi na ugonyo. Kubalulekile ukuba zonke izitofu zokugonya zilungele iminyaka yakho ngaphambi kokuqala unyango lwakho ngenaliti ye-ustekinumab. Awunalo ugonyo ngexesha lonyango ngaphandle kokuthetha nogqirha wakho. Kubaluleke ngakumbi ukuba ungalufumani ugonyo lwe-BCG unyaka omnye ngaphambi konyango lwakho, ngexesha lonyango lwakho, kunye nonyaka omnye emva konyango lwakho. Thetha nogqirha wakho ukuba kukho umntu osendlwini yakho ofuna ukufumana isitofu ngexesha lonyango lwakho ngenaliti ye-ustekinumab.
• Kuya kufuneka uyazi ukuba inaliti ye-ustekinumab inokunciphisa amandla akho okulwa usulelo kwiibhaktiriya, intsholongwane kunye nefungi kwaye wandise umngcipheko wokuba ufumane usulelo olubi okanye olusongela ubomi. Tshela ugqirha wakho ukuba uhlala ufumana naluphi na uhlobo losulelo okanye ukuba unayo okanye ucinga ukuba unalo naluphi na uhlobo losulelo ngoku. Oku kubandakanya izilonda ezitsha okanye ezitshintshayo zolusu, ukosuleleka okuncinci (njengokucheba okuvulekileyo okanye izilonda), usulelo olufikayo (olufana nezilonda ezibandayo), kunye nosulelo olungapheliyo olungapheliyo. Ukuba ufumana naziphi na kwezi mpawu zilandelayo ngexesha okanye emva nje konyango lwakho ngenaliti ye-ustekinumab, biza ugqirha ngoko nangoko: ubuthathaka; ukubila; Ukugodola; iintlungu zemisipha; umqala obuhkungu; ukukhohlela; ukuqhawukelwa ngumphefumlo; ifiva; ukuhla ukusinda; ukudinwa kakhulu; iimpawu ezifana nomkhuhlane; ulusu olufudumeleyo, olubomvu, okanye olubuhlungu; ukuchama kabuhlungu, kunzima, okanye rhoqo; urhudo; isisu esibuhlungu; okanye ezinye iimpawu zosulelo.
• Kuya kufuneka uyazi ukuba ukusebenzisa inaliti ye-ustekinumab kwandisa umngcipheko wokuba uza kuba nesifo sephepha (i-TB; usulelo olubi lwemiphunga), ngakumbi ukuba sele wosulelwe sisifo sephepha kodwa ungenazo iimpawu zesi sifo. Xelela ugqirha wakho ukuba ukhe wakha okanye wakha wanayo na i-TB, ukuba ngaba wakhe wahlala kwilizwe apho ixhaphake kakhulu i-TB, okanye ukuba ukhe wakufutshane nomntu one-TB. Ugqirha wakho uza kwenza uvavanyo lolusu ukuze abone ukuba unesifo se-TB esingasebenziyo. Ukuba kukho imfuneko, ugqirha wakho uya kukunika amayeza ukunyanga esi sifo phambi kokuba uqale ukusebenzisa inaliti ustekinumab. Ukuba unazo naziphi na kwezi mpawu zilandelayo ze-TB, okanye ukuba uvela kwezi mpawu ngexesha lonyango lwakho, tsalela umnxeba kwangoko: ukukhohlela, iintlungu esifubeni, ukukhohlela igazi okanye amafinyila, ubuthathaka okanye ukudinwa, ukwehla emzimbeni, ukungabi namdla wokutya, Ukugodola, umkhuhlane, okanye ukubila ebusuku.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Sebenzisa idosi ephosiweyo kwakamsinya nje emva kokuba uyikhumbule kwaye emva koko uqhubeke neshedyuli yakho yethamo yesiqhelo. Sukusebenzisa idosi ephindwe kabini ukwenza eyilahlekileyo.

Inaliti yeUstekinumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• i-runny, impumlo efakiweyo, okanye ukuthimla
• ukudinwa
• ubomvu okanye ukucaphuka kwindawo yenaliti
• isicaphucaphu
• ukugabha
• intlungu edibeneyo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu okanye ezo zidweliswe kwiCandelo LOKUKHUSELEKILEYO, Biza ugqirha ngoko nangoko:

• ukuxhuzula
• ukudideka
• utshintsho lombono
• ndiziva ndidiniwe
• irhashalala
• ukurhawuzelela
• urhwebo
• ukudumba kobuso, iinkophe, ulwimi, okanye umqala
• ubunzima bokuphefumla
• ukuqina esifubeni okanye emqaleni

Inaliti yeUstekinumab inokunyusa umngcipheko wokuba ube nomhlaza. Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza.

Inaliti yeUstekinumab inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Gcina iibhotile ze-ustekinumab kunye neesirinji ezizalisiweyo kwifriji, kodwa ungazibandisi.Gcina iibhotile kunye neesirinji ezizalisiweyo zithe nkqo kwiibhokisi zazo zokuqala ukuzikhusela ekukhanyeni. Lahla naliphi na iyeza eliphelelwe lixesha okanye elingasafunekiyo. Thetha kumachiza wakho malunga nokulahla ngokufanelekileyo amayeza akho.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwisitofu se-ustekinumab.

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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