Enzalutamide

Umxholo

• Ngaphambi kokuba uthathe i-enzalutamide,
• I-Enzalutamide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Enzalutamide isetyenziselwa ukunyanga umhlaza wedlala lobudoda osele unwenwele nakwamanye amalungu omzimba emadodeni kwaye abo bancedwe lunyango oluthile notyando olwehlisa amanqanaba e testosterone. Isetyenziselwa ukunyanga umhlaza wedlala lobudoda emadodeni angakhange ancedwe ngonyango oluthile kunye notyando olwehlisa amanqanaba e testosterone. U-Enzalutamide ukwiklasi yamayeza abizwa ngokuba yi-androgen receptor inhibitors. Isebenza ngokuthintela iziphumo ze-androgen (ihomoni yokuzala eyindoda) ukumisa ukukhula kunye nokusasazeka kweeseli zomhlaza.

I-Enzalutamide iza njengecwecwe okanye iphilisi ukuyithatha ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kube kanye ngemini. Thatha i-enzalutamide ngexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-enzalutamide ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi okanye iifomsile ngokupheleleyo; musa ukuchoboza, ukuhlafuna, ukwahlula, ukunyibilika, okanye ukuvula.

Ugqirha wakho angakuxelela ukuba uyeke ukuthatha i-enzalutamide okwexeshana okanye unciphise idosi yakho xa uneziphumo ebezingalindelekanga ngexesha lonyango lwakho. Qiniseka ukuba uthetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho nge-enzalutamide.

Ukuba ugqirha wakho umisele elinye iyeza elinje nge-degarelix (Firmagon), goserelin (Zoladex), histrelin (Supprelin LA, Vantas), leuprolide (Eligard, Lupron, kwiLupaneta Pack), okanye i-triptorelin (Trelstar, Triptodur) ukunyanga umhlaza wesibeletho , kuya kufuneka uqhubeke nokufumana la mayeza ngexesha lonyango lwakho nge-enzalutamide.

Qhubeka nokuthatha i-enzalutamide nokuba uziva uphilile. Sukuyeka ukuthatha i-enzalutamide ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-enzalutamide,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-enzalutamide, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-enzalutamide okanye iifomsile. Buza usokhemesti wakho okanye ujonge ulwazi lomenzi wesigulana uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: dihydroergotamine (DHE 45, Migranal), ergotamine (eMigergot, eCafergot), fentanyl (Actiq, Duragesic, Fentora, Subsys, abanye), gemfibrozil (Lopid), itraconazole (Onmel, Sporanox), omeprazole (Prilose) , phenytoin (Dilantin, Phenytek), pimozide (Orap), quinidine (eNuedexta), rifabutin (Mycobutin, eTalicia), rifampin (Rimactane, eRifamate, eRifater), rifapentine (Priftin), sirolimus (rapamune) (IPrograf). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-enzalutamide, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ukhe waxhuzula okanye wenzakala, wenzakele ebuchotsheni, unethumba ebuchotsheni, unengxaki yokuchaphazela ubuchopho (unxibelelwano olungaqhelekanga phakathi kwemithambo kunye nemithambo ebuchotsheni eyenzeka ngaphambi kokuzalwa kwaye inokubangela ukopha kwingqondo), amathambo aphukileyo, i-osteoporosis (imeko apho amathambo esiba buthathaka kwaye aphele kwaye aphuke ngokulula), isifo seswekile, amanqanaba aphezulu e-cholesterol, uxinzelelo lwegazi, isifo sentliziyo, okanye ukubethwa sistroke okanye i-ministroke.
• Kuya kufuneka uyazi ukuba i-enzalutamide kuphela ukuze isetyenziswe emadodeni. Abasetyhini akufuneki bathathe la mayeza, ngakumbi ukuba bayakhulelwa okanye banokukhulelwa okanye ukuncancisa. Abasetyhini, ngakumbi abo bakhulelweyo okanye abanokukhulelwa akufuneki bachukumise i-enzalutamide capsules. Ukuba ithathwa ngabafazi abakhulelweyo, i-enzalutamide inokulimaza umbungu. Ukuba umfazi okhulelweyo uthatha i-enzalutamide, kufuneka abize ugqirha wakhe ngokukhawuleza.
• Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuzala emadodeni. Nangona kunjalo, awunakucinga ukuba iqabane lakho labasetyhini alinakukhulelwa. Ukuba iqabane lakho likhulelwe, kuya kufuneka usebenzise ikhondom xa usabelana ngesondo ngexesha lonyango lwakho kunye ne-enzalutamide kunye neenyanga ezi-3 emva kwedosi yakho yokugqibela. Ukuba iqabane lakho alikhulelwanga kodwa linokukhulelwa, kuya kufuneka nisebenzise indlela efanelekileyo yokulawula ukuzalwa nanini na nisabelana ngesondo ngexesha lonyango kunye neenyanga ezi-3 emva kwedosi yokugqibela.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-enzalutamide.
• Kuya kufuneka uyazi ukuba i-enzalutamide inokubangela ukuxhuzula. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba awukhumbuli kude kube lusuku olulandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Musa ukuthatha ngaphezulu kwedosi enye ngosuku olunye kwaye ungathathi idosi ephindwe kabini ukwenza enye ephosiweyo.

I-Enzalutamide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ubuthathaka
• ukudinwa
• intlungu edibeneyo
• ubuthathaka bemisipha okanye ukuqina
• ukuhla ukusinda
• Ukuphelelwa ngumdla wokutya
• intloko ebuhlungu
• isiyezi
• ukutshisa, ukuba ndindisholo, okanye ukurhawuzelela iingalo, izandla okanye iinyawo
• Ukuncipha kwengqondo yokuthinta okanye ukubanako ukuziva uvakalelo
• kushushu
• ubunzima bokulala okanye ukulala
• ixhala
• kunzima ukukhumbula, ukucinga, okanye ukunika ingqalelo
• urhudo
• ukuqhina
• ukurhawuzelela
• isikhumba esomileyo
• impumlo
• ukuchama rhoqo
• utshintsho lwencasa

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ukuxhuzula
• intloko ebuhlungu; ukudideka; okanye utshintsho lombono
• ukudumba kobuso, ulwimi, imilebe, umqala, iingalo, imilenze, izandla okanye iinyawo
• umkhuhlane, ukukhohlela, umqala obuhlungu, okanye ezinye iimpawu zosulelo
• iintlungu zesifuba
• ukuqhawukelwa ngumphefumlo
• iintlungu emqolo, izihlunu, kunye / okanye imilenze
• ukuba ndindisholo okanye ukurhawuzelela iimpundu okanye imilenze
• ubunzima bokulawula ukuchama okanye ukuhamba kwamathumbu
• ubunzima bokuphefumla
• ukuwa
• amathambo aqhekekileyo okanye ukwaphuka
• i-hallucinating (ukubona izinto okanye ukuva amazwi angabikho)
• ukwandiswa kwamabele emadodeni
• umchamo opinki okanye obomvu

I-Enzalutamide inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• ukuxhuzula

Gcina lonke ixesha lokudibana nogqirha wakho.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Xtandi^®