Elvitegravir, Cobicistat, Emtricitabine, kunye neTenofovir

Umxholo

• Ngaphambi kokuba uthathe i-elvitegravir, i-cobicistat, i-emtricitabine, kunye ne-tenofovir,
• Elvitegravir, cobicistat, emtricitabine, kunye ne-tenofovir kunokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kumacandelo ESILUMKISO ESIBALULEKILEYO OKANYE AMANYATHELO ATHILE, biza ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

I-Elvitegravir, i-cobicistat, i-emtricitabine, kunye ne-tenofovir akufuneki zisetyenziselwe ukunyanga usulelo lwentsholongwane ye-hepatitis B (HBV; usulelo lwesibindi oluqhubekayo). Xelela ugqirha wakho ukuba unayo okanye ucinga ukuba unayo i-HBV. Ugqirha wakho angakuvavanya ukuze ubone ukuba unayo i-HBV ngaphambi kokuba uqale unyango lwakho nge-elvitegravir, cobicistat, emtricitabine, kunye ne-tenofovir. Ukuba unayo i-HBV kwaye uthatha i-elvitegravir, i-cobicistat, i-emtricitabine, kunye ne-tenofovir, imeko yakho inokuba mandundu mandundu xa uyeka ukuthatha eli yeza. Ugqirha wakho uya kukuvavanya kwaye a-odole uvavanyo lweelebhu rhoqo kwiinyanga ezininzi emva kokuba uyekile ukuthatha eli yeza ukubona ukuba i-HBV yakho iye yanda.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile ngaphambi nangexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwi-elvitegravir, cobicistat, emtricitabine, kunye ne-tenofovir.

Thetha nogqirha wakho malunga nomngcipheko wokuthatha i-elvitegravir, i-cobicistat, i-emtricitabine, kunye ne-tenofovir.

Indibaniselwano ye-elvitegravir, cobicistat, emtricitabine, kunye ne-tenofovir (Genvoya, Stribilid) isetyenziselwa ukunyanga usulelo lwe-immunodeficiency virus (HIV) kubantu abadala nakubantwana abangakhange banyangwe ngamanye amayeza e-HIV okanye ukubuyisela unyango lwangoku kubantu abathile sele ukuthatha amayeza e-HIV. Indibaniselwano ye-elvitegravir, i-cobicistat, i-emtricitabine, kunye ne-tenofovir ikudidi lwamayeza abizwa ngokuba zii-antivirals. Umsebenzi we-Elvitegravir, emtricitabine, kunye ne-tenofovir ngokunciphisa inani le-HIV egazini. ICobicistat inceda ukugcina i-elvitegravir emzimbeni ixesha elide ukuze amayeza abe nefuthe elikhulu. Nangona indibaniselwano ye-elvitegravir, i-cobicistat, i-emtricitabine kunye ne-tenofovir zingayi kuyinyanga i-HIV, la mayeza angalinciphisa ithuba lakho lokufumana isifo se-immunodeficiency syndrome (i-AIDS) kunye nezifo ezinxulumene ne-HIV ezinje ngezifo ezinzulu okanye umhlaza. Ukuthatha la mayeza kunye nokwabelana ngesondo okukhuselekileyo nokwenza olunye utshintsho kwindlela yokuphila kunokunciphisa umngcipheko wokuhambisa intsholongwane kagawulayo kwabanye abantu.

Indibaniselwano ye-elvitegravir, i-cobicistat, i-emtricitabine, kunye ne-tenofovir iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kunye nokutya kanye ngemini. Thatha i-elvitegravir, i-cobicistat, i-emtricitabine, kunye ne-tenofovir ngexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-elvitegravir, i-cobicistat, i-emtricitabine, kunye ne-tenofovir ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

I-Elvitegravir, i-cobicistat, i-emtricitabine, kunye ne-tenofovir ziyanceda ekulawuleni usulelo lwe-HIV kodwa zingalunyangi. Qhubeka nokuthatha i-elvitegravir, i-cobicistat, i-emtricitabine, kunye ne-tenofovir nokuba uziva uphilile. Sukuyeka ukuthatha i-elvitegravir, i-cobicistat, i-emtricitabine, kunye ne-tenofovir ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-elvitegravir, i-cobicistat, i-emtricitabine, kunye ne-tenofovir,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-elvitegravir, i-cobicistat, i-emtricitabine, okanye i-tenofovir, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwi-elvitegravir, cobicistat, emtricitabine, kunye neepilisi ze-tenofovir. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha nawaphi na amayeza alandelayo: alfuzosin (Uroxatral); carbamazepine (Carbatrol, Epitol, Tegretol, abanye), cisapride (Propulsid) (ayifumaneki eMelika); amayeza e-ergot anje nge-dihydroergotamine (iDHE 45, Migranal), ergotamine (Ergomar, eCafergot, eMigergot), kunye ne-methylergonovine (Methergine); lomitapide (Juxtapid); I-lovastatin (Altoprev); ilurasidone (iLatuda); midazolam (Iindinyana) ngomlomo; phenobarbital; phenytoin (iDilantin, iPhenytek); ipimozide (Orap); irifampin (Rifadin, Rimactane, eRifamate, eRifater); I-wort yaseSt. i-sildenafil (i-Revatio kuphela, uphawu olusetyenziselwa isifo semiphunga); isimvastatin (Simcor, Zocor, kwiVytorin); okanye i-triazolam (Halcion). Ugqirha wakho uyakukuxelela ukuba ungathathi i-elvitegravir, i-cobicistat, i-emtricitabine, kunye ne-tenofovir ukuba uthatha elinye okanye ngaphezulu kula mayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: aminoglycoside antibiotics njenge-gentamicin; i-anticoagulants ('thinner') ezinje ngeapixaban (Eliquis), ixabtraxaban (Bevyxxa), dabigatran (Pradaxa), edoxaban (Savaysa), rivaroxaban powder (Xarelto), kunye warfarin (Coumadin, Jantoven); amayeza okubola anje nge-itraconazole (Onmel, Sporanox), ketoconazole, kunye ne-voriconazole (Vfend); amayeza antiviral anje ngeacyclovir (Sitavig, Zovirax), cidofovir, ganciclovir (Cytovene), valacyclovir (Valtrex), kunye valganciclovir (Valcyte); i-aspirin kunye nezinye iyeza ezichasayo (i-NSAIDs) ezinje nge-ibuprofen (Advil, Motrin) kunye ne-naproxen (Aleve, Naprosyn); atorvastatin (Lipitor, kwiCaduet); i-benzodiazepines ezinjenge-clonazepam (iKlonopin), i-clorazepate (iGen-Xene, iTranxene), i-diazepam (i-Diastat, iValium), i-estazolam, i-flurazepam, kunye ne-midazolam enikezwe ngaphakathi (emthanjeni); ii-beta blockers ezinje nge-metoprolol (Lopressor, Toprol-XL, in Dutoprol) kunye ne-timolol; i-bosentan (iTracleer); buprenorphine kunye naloxone (Bunavail, Suboxone); buspirone; ii-calcium channel blocker ezinje nge-amlodipine (Norvasc), diltiazem (Cardizem, Diltzac, Tiazac, abanye), felodipine, nicardipine (Cardene), nifedipine (Adalat CC, Afeditab CR, Procardia), kunye neverapamil (Calan, Verelan, eTarka); i-clarithromycin (i-Biaxin, kwi-PrevPac); icolchicine (Colcrys, Mitagare, kwiCol-Probenecid); dexamethasone; i-ethosuximide (iZarontin), izinto zokucwangcisa zehomoni (iipilisi zolawulo lokuzalwa, isiziba, iringi yelungu lobufazi, okanye inaliti); amayeza oxinzelelo afana ne-amitriptyline, bupropion (Aplenzin, Forfivo XL, Wellbutrin, Zyban), desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Brisdelle, Paxil, Pexeva), kunye ne-trazodone; amanye amayeza e-HIV okanye i-AIDS kubandakanya i-cobicistat (iTybost, e-Evotaz, e-Prezcobix), emtricitabine (Emtriva, e-Atripla, e-Complera, e-Truvada), lamivudine (Epivir, e-Combivir, e-Epzicom, e-Trizivir, abanye), ritonavir ( ENorvir, eKaletra, eTechnivie), kunye ne-tenofovir (eViread, eAtripla, eComplera, eTruvada); fentanyl (Actiq, Duragesic, Subsys); amayeza okubetha kwentliziyo ngokungaqhelekanga njenge-amiodarone (Nexterone, Pacerone), digoxin (Lanoxin), disopyramide (Norpace), flecainide, lidocaine (Xylocaine), mexiletine, propafenone (Rythmol), kunye nequinidine (eNuedexta); amayeza athintela amajoni omzimba anje ngecyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), kunye netacrolimus (Prograf); naloxone (Evzio, Narcan); i-oxcarbazepine (iOxtellar XR, iTrileptal); iperphenazine; iquetiapine (iSeroquel); i-phosphodiesterase (PDE5) inhibitors ezinje nge-sildenafil (Viagra), tadalafil (Adcirca, Cialis), kunye ne-vardenafil (Levitra, Staxyn); irifabutin (Mycobutin); irifapentine (Priftin); irisperidone (iRisperdal); isalmeterol (iSerevent, eAdvair); ngomlomo okanye nge-inhaled steroids njenge-betamethasone, budesonide (Pulmicort), ciclesonide (Alvesco, Omnaris), dexamethasone, fluticasone (Flonase, Flovent, eAdvair), methylprednisolone (Medrol). mometasone (eDulera). i-prednisone (iRayos), kunye ne-triamcinolone; i-telithromycin (Ketek; ayisafumaneki e-US); thioridazine; i-tramadol; kunye ne-zolpidem (Ambien, Edluar, Intermezzo, Zolpimist). Amanye amayeza amaninzi anokusebenzisana ne-elvitegravir, cobicistat, emtricitabine, kunye ne-tenofovir, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• ukuba uthatha ii-antacids ezine-aluminium, i-magnesium, okanye i-calcium (Maalox, Mylanta, others), zithathe iiyure ezi-2 ngaphambi okanye iiyure ezi-2 emva kwe-elvitegravir, cobicistat, emtricitabine, kunye ne-tenofovir
• xelela ugqirha wakho ukuba ukhe wakha wanemiqathango ekhankanyiweyo kwicandelo LESILUMKISO ESIBALULEKILEYO, iingxaki zamathambo kubandakanya i-osteoporosis (imeko apho amathambo esiba buthathaka kwaye abuthathaka kwaye aphule ngokulula) okanye uqhekeko lwethambo, naluphi na uhlobo losulelo olungahambiyo kude okanye okuzayo kuhamba njengesifo sephepha (i-TB; uhlobo losulelo lwemiphunga) okanye i-cytomegalovirus (i-CMV; usulelo lwentsholongwane olunokubangela iimpawu kwizigulana ezinamajoni omzimba abuthathaka), okanye isifo sesibindi okanye sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-elvitegravir, i-cobicistat, i-emtricitabine, kunye ne-tenofovir, tsalela ugqirha kwangoko. Akufuneki uncancise xa wosulelwe yi-HIV okanye ukuba uthatha i-elvitegravir, i-cobicistat, i-emtricitabine kunye ne-tenofovir.
• Kuya kufuneka uyazi ukuba ngelixa uthatha amayeza ukunyanga usulelo lwe-HIV, amajoni akho omzimba angomelela kwaye aqale ukulwa nezinye izifo ezazisele zisemzimbeni wakho. Oku kunokubangela ukuba ube neempawu zolu sulelo. Ukuba uneempawu ezintsha okanye eziba mandundu ngexesha lonyango lwakho nge-elvitegravir, cobicistat, emtricitabine, kunye ne-tenofovir, qiniseka ukuxelela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule ngokutya. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

Elvitegravir, cobicistat, emtricitabine, kunye ne-tenofovir kunokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• ubunzima bokulala okanye ukulala
• amaphupha angaqhelekanga
• urhudo
• irhasi
• irhashalala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kumacandelo ESILUMKISO ESIBALULEKILEYO OKANYE AMANYATHELO ATHILE, biza ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

• ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukudinwa
• ubunzima bokuginya okanye ukuphefumla
• ukuncipha kokuchama
• iintlungu ezingalweni, ezandleni, ezinyaweni okanye emilenzeni
• iintlungu kwinxalenye ephezulu yesisu sakho
• Ukuphelelwa ngumdla wokutya
• Iimpawu ezinjengomkhuhlane
• isicaphucaphu
• ukugabha
• ukudinwa kakhulu
• ukopha okungaqhelekanga okanye ukugruzuka
• ubuthathaka
• isiyezi
• intloko elula
• ukukhawuleza kwentliziyo okanye okungaqhelekanga
• ingxaki yokuphefumla
• Umchamo omnyama otyheli okanye omdaka
• intshukumo ekhanyayo emathunjini
• mthubi ulusu okanye amehlo
• ndiziva ndibanda, ngakumbi ezingalweni okanye emilenzeni
• iintlungu zemisipha

Elvitegravir, cobicistat, emtricitabine, kunye ne-tenofovir kunokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Gcina isibonelelo se-elvitegravir, i-cobicistat, i-emtricitabine, kunye ne-tenofovir ngesandla. Sukulinda de uphelelwe ngamayeza ukuze uphinde uzalise amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Genvoya^® (Equlathe iCobicistat, Elvitegravir, Emtricitabine, Tenofovir)
• Uluhlu^® (Equlathe iCobicistat, Elvitegravir, Emtricitabine, Tenofovir)