Inaliti yeTemozolomide

Umxholo

• Phambi kokufumana i-temozolomide,
• I-Temozolomide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Temozolomide isetyenziselwa ukunyanga iintlobo ezithile zamathumba engqondo. I-Temozolomide ikwiklasi yamayeza abizwa ngokuba ziiarhente zealkylating. Isebenza ngokunciphisa okanye ukumisa ukukhula kweeseli zomhlaza emzimbeni wakho.

Inaliti yeTemozolomide iza njengomgubo oza kongezwa kulwelo kwaye itofwe ngaphezulu kwemizuzu engama-90 efakwa ngaphakathi (emthanjeni) ngugqirha okanye ngumongikazi. Ihlala itofwa kanye ngemini. Kwezinye iintlobo zamathumba obuchopho, i-temozolomide inikwa yonke imihla kangangeentsuku ezingama-42 ukuya kuma-49. Emva koko, emva kwekhefu leentsuku ezingama-28, inokunikwa kube kanye ngemini kangangeentsuku ezintlanu zilandelelana, kulandele ikhefu leentsuku ezingama-23 ngaphambi kokuphinda umjikelo wethamo elilandelayo. Unyango lwezinye iintlobo zamathumba obuchopho, i-temozolomide inikwa kube kanye ngemini kangangeentsuku ezi-5 zilandelelana, kulandele ikhefu leentsuku ezingama-23 ngaphambi kokuphinda umjikelo wedosi olandelayo. Ubude bonyango buxhomekeke kwindlela ophendula ngayo emzimbeni wakho kunye nohlobo lomhlaza onawo.

Ugqirha wakho unokufuna ukulibazisa unyango lwakho okanye uhlengahlengise idosi yakho ngokuxhomekeke kwimpendulo yakho kunyango kunye naziphi na iziphumo ebezingalindelekanga ohlangabezana nazo. Thetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho ngetemozolomide.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Phambi kokufumana i-temozolomide,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-temozolomide, dacarbazine (DTIC-Dome) nawaphi na amanye amayeza, okanye nasiphi na isithako se-temozolomide injection. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: carbamazepine (Carbatrol, Epitol, Tegretol); co-trimoxazole (Bactrim, Septra); phenytoin (iDilantin, iPhenytek); i-steroids ezinje nge-dexamethasone (i-Decadron, i-Dexone), i-methylprednisolone (Medrol), kunye ne-prednisone (Deltasone); kunye ne-valproic acid (iStavzor, ​​iDepakene).
• xelela ugqirha wakho ukuba ukhe unesifo sezintso okanye sesibindi.
• Kuya kufuneka uyazi ukuba i-temozolomide inokuphazamisa ukuveliswa kwesidoda emadodeni. Nangona kunjalo, awunakucinga ukuba awunakho ukukhulelwa omnye umntu. Tshela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa, okanye ukuba ucwangcisa ukuba notata umntwana. Wena okanye iqabane lakho akufuneki ukuba ukhulelwe ngelixa ufumana i-temozolomide. Sebenzisa indlela ethembekileyo yolawulo lokuzalwa ukukhusela ukukhulelwa. Ukuba ukhulelwa ngelixa ufumana i-temozolomide, tsalela umnxeba ugqirha wakho. I-Temozolomide inokwenzakalisa umntwana ongekazalwa.
• xelela ugqirha wakho ukuba uncelisa. Akufanelanga ukuncancisa ngelixa ufumana i-temozolomide.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

I-Temozolomide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• urhudo
• ukuqhina
• Ukuphelelwa ngumdla wokutya
• izilonda emlonyeni nasemqaleni
• intloko ebuhlungu
• ulusu oluthuthu
• ukunqongophala kwamandla
• ukulahleka kwemali eseleyo okanye yokulungelelanisa
• isiqaqa
• isiyezi
• ukulahleka kweenwele
• ukuphuthelwa
• iingxaki zememori
• iintlungu, ukurhawuzelela, ukudumba, okanye ububomvu kwindawo apho lalifakwe khona iyeza
• utshintsho kumbono

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ukopha okungaqhelekanga okanye ukugruzuka
• obomvu okanye omnyama, izitulo zokulinda
• umchamo opinki, obomvu, okanye omnyama
• ukukhohlela okanye ukugabha igazi okanye into ebonakala ngathi yindawo yekhofi
• umkhuhlane, umqala obuhlungu, ukukhohlela nokuxinana okuqhubekayo, okanye ezinye iimpawu zosulelo
• ukudinwa okungaqhelekanga okanye ubuthathaka
• irhashalala
• ayikwazi ukuhambisa icala elinye lomzimba
• ukuqhawukelwa ngumphefumlo
• ukuxhuzula
• mthubi ulusu okanye amehlo
• iintlungu kwinxalenye ephezulu yesisu
• ukuncipha kokuchama

I-Temozolomide inokunyusa umngcipheko wokuba uphuhlise eminye imihlaza. Thetha nogqirha wakho malunga nomngcipheko wokuthatha i-temozolomide.

I-Temozolomide inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• ukopha okungaqhelekanga okanye ukugruzuka
• obomvu okanye omnyama, izitulo zokulinda
• umchamo opinki, obomvu, okanye omnyama
• ukukhohlela okanye ukugabha igazi okanye into ebonakala ngathi yindawo yekhofi
• umkhuhlane, umqala obuhlungu, ukukhohlela nokuxinana okuqhubekayo, okanye ezinye iimpawu zosulelo

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo zaselebhu ngaphambi, ngexesha, nasemva konyango lwakho ukujonga impendulo yomzimba wakho kunye netemozolomide ukubona ukuba iiseli zakho zegazi ziyachaphazeleka kweli chiza.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• I-Temodar^®