Idelalisib

Umxholo

• Ngaphambi kokuba uthathe idelalisib,
• I-Idelalisib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

I-Idelalisib inokubangela ukonakala okanye ubomi obusongela ukonakala kwesibindi. Tshela ugqirha wakho ukuba ukhe unesifo sesibindi. Umngcipheko wokulimala kwesibindi unokunyuswa kubantu abathatha amanye amayeza aziwayo ukuba abangele ukonakala kwesibindi, nakubantu esele benesifo sesibindi. Xelela ugqirha wakho kunye nosokhemesti malunga namayeza owathathayo ukuze bakwazi ukujonga ukuba ngaba nawaphi na amayeza akho anokuwonyusa umngcipheko wokuba uya kukhula umonakalo wesibindi ngexesha lonyango lwakho kunye ne-idelalisib Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: ukudinwa kakhulu, ukuncipha kokutya, ukuncipha, isicaphucaphu, ukugabha, ukopha okungaqhelekanga okanye ukugruzuka, ulusu lube luthuthu okanye amehlo, umchamo omnyama tyheli okanye umbala omdaka, isitulo esimthubi , okanye iintlungu kwinxalenye ephezulu yesisu.

I-Idelalisib inokubangela urhudo, isifo sokukrala (ukudumba kwamathumbu amakhulu), okanye imingxunya esiswini okanye emathunjini. Tshela ugqirha wakho ukuba unesifo sohudo okanye ukuba uke waba ne-colitis okanye ezinye iimeko ezichaphazela isisu okanye isisu sakho. Umngcipheko wohudo unokunyuswa kubantu abathatha amanye amayeza awaziwayo abangela urhudo. Xelela ugqirha wakho kunye nosokhemesti malunga namayeza owathathayo ukuze bakwazi ukujonga ukuba ngaba nawaphi na amayeza akho anokuwonyusa umngcipheko wokuba uza kuba nesifo sorhudo ngexesha lonyango lwakho kunye ne-idelalisib. inani lakho lokuhamba kwamathumbu ngosuku lonyuka ngo-6 okanye nangaphezulu, isisu okanye iintlungu, ukugodola, umkhuhlane, isicaphucaphu, okanye ukugabha.

I-Idelalisib inokubangela ukuba i-pneumonitis (okanye ukuvuvukala kwemiphunga). Tshela ugqirha wakho ukuba unesifo semiphunga okanye unengxaki yokuphefumla. Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: ukukhwehlela okutsha okanye okuya kusiba mandundu, ukuphefumla nzima, ukuphefumla, okanye ukuphefumla kancinci.

I-Idelalisib inokubangela ukosuleleka okunamandla okanye okusongela ubomi. Tshela ugqirha wakho ukuba unentsholongwane, okanye ukuba unayo okanye unayo i-cytomegalovirus (i-CMV; intsholongwane yentsholongwane engabangela iimpawu kwizigulane ezinamajoni omzimba obuthathaka). Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: umkhuhlane, umqala obuhlungu, ukugodola, ukuba buhlungu, ukuhlala rhoqo, okanye ukuba nzima ukuchama, okanye ezinye iimpawu zosulelo.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwi-idelalisib.

Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-idelalisib.

I-Idelalisib isetyenziswa kunye nelinye iyeza rituximab (Rituxan) ukunyanga i-lymphocytic leukemia (CLL; uhlobo lomhlaza oqala kumaseli egazi amhlophe) kubantu abanomhlaza obuyileyo emva kokufumana olunye unyango lomhlaza. Isetyenziselwa ukunyanga iintlobo ezithile ze-follicular lymphoma (FL; uhlobo lomhlaza oqala kwiiseli ezimhlophe zegazi) kunye ne-lymphocytic lymphoma encinci (i-SLL: uhlobo lomhlaza oqala kwiiseli ezimhlophe zegazi) kubantu abanomhlaza buya emva kokuphathwa ubuncinci ngamanye amayeza ama-2. U-Idelalisib ukwiklasi yamayeza abizwa ngokuba yi-kinase inhibitors. Isebenza ngokuthintela isenzo seprotein engaqhelekanga ebonisa iiseli zomhlaza ukuba zande. Oku kunceda ukunqanda ukusasazeka kweeseli zomhlaza.

I-Idelalisib iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kabini ngemini. Thatha idelalisib ngamaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha idelalisib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze.

Ugqirha wakho unokunciphisa idosi ye-idelalisib okanye akuxelele ukuba uyeke ukuthatha amayeza okwexeshana okanye ngokusisigxina ukuba uneziphumo ebezingalindelekanga ngexesha lonyango lwakho. Oku kuxhomekeke ekusebenzeni kakuhle kweyeza kunye neziphumo ebezingalindelekanga ohlangabezana nazo. Thetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho. Qhubeka uthathe i-idelalisib nokuba uziva uphilile. Ungayeki ukuthatha i-idelalisib ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe idelalisib,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-idelalisib, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-idelalisib. Ukuba ukhe wakha wasabela kakubi emzimbeni ngaphambili, njengokudumba kobuso, imilebe okanye umqala; ubunzima bokuginya okanye ukuphefumla; okanye uxobuka, ulusu olunamabala amdaka, ugqirha wakho uyakukuxelela ukuba ungathathi i-idelalisib Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: carbamazepine (Carbatrol, Epitol, Equetro, nabanye); i-clarithromycin (i-Biaxin, kwi-PrevPac); itraconazole (Onmel, Sporanox); ketoconazole (Nizoral); amayeza asetyenziselwa ukunyanga intsholongwane kaGawulayo (i-HIV) efana ne-efavirenz (Sustiva, e-Atripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, e-Kaletra, e-Technivie); midazolam; nefazodone; phenobarbital; phenytoin (iDilantin, iPhenytek); ipioglitazone (Actos, eActoplus Met, eDuetact, eOseni); irifabutin (Mycobutin); kunye nerifampin (Rifadin, Rimactane, eRifamate, eRifater). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-idelalisib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho kunye nosokhemisti ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi i-wort yaseSt. Akufanele uthathe i-wort yaseSt.John ngexesha lonyango lwakho nge-idelalisib.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ucwangcise ukuba ngutata womntwana. Akufanele ukhulelwe ngexesha lonyango lwakho nge-idelalisib.Kuya kufuneka usebenzise ulawulo lokuzalwa ukuthintela ukukhulelwa ngexesha lonyango lwakho kunye ne-idelalisib kwaye ubuncinci inyanga e-1 emva kwedosi yakho yokugqibela. Ukuba uyindoda kwaye iqabane lakho linokukhulelwa, kuya kufuneka usebenzise ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho kunye neenyanga ezi-3 emva kwedosi yakho yokugqibela. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa uthatha idelalisib, biza ugqirha wakho ngokukhawuleza. U-Idelalisib unokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncelise ngelixa uthatha i-idelalisib kwaye ubuncinci kwinyanga enye emva kwedosi yakho yokugqibela.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yamagilebhisi ngelixa uthatha eli yeza.

Ukuba uphoswa ithamo le-idelalisib ngaphantsi kweeyure ezingama-6, thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule kwaye emva koko uthathe idosi elandelayo ngexesha elimiselweyo. Nangona kunjalo, ukuba uphosa idosi ngaphezulu kweeyure ezingama-6, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Idelalisib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• ubunzima bokulala okanye ukulala
• ukunciphisa ukutya
• ukwanda kokoma
• isilungulela
• intlungu edibeneyo
• ukubila ebusuku
• ukunqongophala kwamandla
• ukudumba kwezandla, iinyawo, amaqatha okanye imilenze esezantsi

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• obomvu, ukurhawuzelela, ukuxobuka, okanye isikhumba esidumbileyo
• izilonda ezibuhlungu okanye izilonda kulusu lwakho, emilebeni, okanye emlonyeni
• ubunzima bokuginya okanye ukuphefumla; ukudumba kobuso, imilebe, okanye umqala; imihlathi ukurhawuzelela

I-Idelalisib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nokukhanya, ubushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Zydelig^®