Inaliti yeDulaglutide

Umxholo

• Ngaphambi kokusebenzisa i-dulaglutide,
• Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso.
• I-Dulaglutide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILumkiso ESIBALULEKILEYO, yeka ukusebenzisa i-dulaglutide kwaye utsalele ugqirha kwangoko okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

Inaliti ye-Dulaglutide inokunyusa umngcipheko wokuba uza kuphuhlisa amathumba e-thyroid, kubandakanya i-medullary thyroid carcinoma (MTC; uhlobo lomhlaza wedlala lengqula). Izilwanyana zaselabhoratri ezinikwe i-dulaglutide ziphuhlise amathumba, kodwa ayaziwa ukuba eli yeza lonyusa umngcipheko wamathumba ebantwini. Xelela ugqirha wakho ukuba wena okanye nabani na kusapho lwakho une-MTC okanye i-Multiple Endocrine Neoplasia syndrome yohlobo 2 (MEN 2; imeko ebangela amathumba ngaphezulu kwendlala enye emzimbeni). Ukuba kunjalo, ugqirha wakho uya kukuxelela ukuba ungasebenzisi inaliti ye-dulaglutide. Ukuba unazo naziphi na kwezi mpawu zilandelayo, biza ugqirha ngoko nangoko: iqhuma okanye ukudumba entanyeni; ukudakumba; ubunzima bokugwinya; okanye ukuphefumla okufutshane.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unokuyalela iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwisitofu se-dulaglutide.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango ngenaliti ye-dulaglutide kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Thetha nogqirha wakho malunga nemingcipheko yokusebenzisa inaliti ye-dulaglutide.

Inaliti ye-Dulaglutide isetyenziselwa ukutya kunye nenkqubo yokuzivocavoca ukulawula amanqanaba eswekile yegazi kubantu abadala abanesifo seswekile sesi-2 (imeko apho umzimba ungasebenzisi i-insulin ngokwesiqhelo kwaye ngenxa yoko awukwazi ukulawula ubungakanani beswekile egazini). Inaliti ye-Dulaglutide ikwasetyenziselwa ukunciphisa umngcipheko wokuhlaselwa sisifo sentliziyo, ukubetha, okanye ukufa kubantu abadala abanesifo seswekile seswekile abanesifo sentliziyo okanye abasemngciphekweni wokuhlaselwa sisifo sentliziyo. Inaliti ye-Dulaglutide ayisetyenziswanga ukunyanga isifo seswekile sokuqala (imeko apho umzimba ungayivelisi i-insulin kwaye ngenxa yoko awunakho ukulawula isixa seswekile egazini) okanye isifo seswekile ketoacidosis (imeko enzulu enokuthi ikhule ukuba iswekile ephezulu yegazi ayinyangwa) . Inaliti ye-Dulaglutide ikwiklasi yamayeza abizwa ngokuba yi-incretin mimetics. Isebenza ngokunceda i-pancreas ukuba ikhuphe inani elifanelekileyo le-insulin xa amanqanaba eswekile esegazini ephezulu. I-insulin inceda ukuhambisa iswekile egazini iye kwezinye izicwili zomzimba apho isetyenziselwa khona amandla. Inaliti ye-Dulaglutide ikwasebenza ngokucothisa ukuhamba kokutya ngesisu.

Ixesha elingaphezulu, abantu abanesifo seswekile kunye neswekile ephezulu yegazi banokuba neengxaki ezinzulu okanye ezisongela ubomi, kubandakanya isifo sentliziyo, ukubetha, iingxaki zezintso, ukonakala kwemithambo-luvo kunye neengxaki zamehlo. Sebenzisa amayeza, ukwenza utshintsho kwindlela yokuphila (umzekelo, ukutya, ukwenza umthambo, ukuyeka ukutshaya), kunye nokujonga iswekile yegazi rhoqo kunokunceda ukulawula isifo seswekile kunye nokuphucula impilo yakho. Olu nyango lunokunciphisa amathuba akho okuhlaselwa sisifo sentliziyo, ukubetha, okanye ezinye iingxaki ezinxulumene nesifo seswekile ezinje ngokusilela kwezintso, ukulimala kwentliziyo (ukubindeka, imilenze ebandayo okanye iinyawo; ukunciphisa amandla ezesondo kumadoda nabasetyhini), iingxaki zamehlo, kubandakanya notshintsho okanye ukulahleka kombono, okanye isifo seentsini. Ugqirha wakho kunye nabanye ababoneleli ngempilo bayakuthetha nawe ngeyona ndlela yokulawula isifo sakho seswekile.

Inaliti ye-Dulaglutide iza njengesisombululo (ulwelo) kwipenisi yedosi ekhethiweyo yokufaka inaliti (phantsi kolusu) esiswini sakho, ethangeni, okanye kwingalo ephezulu. Ihlala itofwe kanye ngeveki ngaphandle kokutya. Sebenzisa inaliti ye-dulaglutide ngosuku olunye ngeveki ngalo naliphi na ixesha losuku. Ungalutshintsha usuku lweveki oyisebenzisa i-dulaglutide okoko ibiyi-3 okanye ngaphezulu kweentsuku okoko usebenzise idosi yakho yokugqibela. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa inaliti ye-dulaglutide ngqo njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

Inaliti ye-Dulaglutide ilawula isifo seswekile kodwa ayisinyangi. Qhubeka nokusebenzisa inaliti ye-dulaglutide nokuba uziva uphilile. Sukuyeka ukusebenzisa inaliti ye-dulaglutide ngaphandle kokuthetha nogqirha wakho.

I-Dulaglutide iza kwiipeni zedosi ekhethiweyo enamayeza aneleyo edosi enye. Soloko ujoba i-dulaglutide kwindawo yayo yokubhala; ungaze uyidibanise namanye amayeza.

Yifundisise ngononophelo imiyalelo yomenzi esetyenziswa nonyango. Le miyalelo ichaza indlela yokulungiselela kunye nokujova idosi yenaliti ye-dulaglutide. Qiniseka ukuba ubuza usokhemesti okanye ugqirha ukuba unemibuzo malunga nokuba ungalifaka njani na eliyeza.

Soloko ujonga isisombululo se-dulaglutide ngaphambi kokuba uyitofe. Kufuneka icace, ingenambala, kwaye ikhululeke ngamasuntswana aqinileyo.

Unokufaka i-dulaglutide engalweni yakho ephezulu, ethangeni, okanye kwindawo yesisu. Ungaze ufake i-dulaglutide emthanjeni okanye kwimisipha. Guqula (jikelezisa) indawo yenaliti kwindawo ekhethiweyo yedosi nganye. Unokufaka i-dulaglutide kunye ne-insulin kwindawo enye yomzimba, kodwa akufuneki unike ii-injini ecaleni komnye nomnye.

Ungaze uphinde usebenzise okanye wabelane ngeepeni zokulinganisa. Lahla iipeni kwisitya esinganyangekiyo. Buza ugqirha wakho okanye usokhemesti ngendlela yokusilahla isikhongozeli esinganyangekiyo.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa i-dulaglutide,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-dulaglutide, nawaphi na amanye amayeza, okanye nasiphi na isithako esiku-injection ye-dulaglutide. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Kubaluleke ngakumbi ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo ngomlomo kuba i-dulaglutide inokutshintsha indlela umzimba wakho owabamba ngayo la mayeza. Qiniseka ukuba ukhankanya i-insulin okanye amayeza omlomo eswekile ingakumbi i-sulfonylureas, kubandakanya i-chlorpropamide (Diabinese), glimepiride (Amaryl, e-Avandaryl, e-Duetact), glipizide (Glucotrol), glyburide (DiaBeta, kwiGlucovance), tolazamide, kunye ne-tolbutamide. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wafumana ipancreatitis (ukudumba kwepancreas); isifo seswekile (ukonakala kwamehlo okubangelwa sisifo seswekile); iingxaki ezinzima zesisu, kubandakanya i-gastroparesis (ukuhamba kancinci kokutya ukusuka esiswini ukuya emathunjini amancinci) okanye ezinye iingxaki zokwetyisa ukutya; okanye isifo sezintso okanye sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa usebenzisa inaliti ye-dulaglutide, biza ugqirha wakho.
• buza ugqirha wakho ukuba wenzeni ukuba uyagula, uhlasele usulelo okanye umkhuhlane, amava oxinzelelo angaqhelekanga, okanye wenzakele. Ezi meko zinokuchaphazela iswekile yegazi kunye nenani le-dulaglutide onokuyifuna.

Qiniseka ukuba ulandela yonke imithambo kunye nezincomo zokutya ezenziwe ngugqirha wakho okanye ugqirha otya ukutya.

Sebenzisa idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule kwaye uqhubeke neshedyuli yakho yesiqhelo yeveki. Nangona kunjalo, ukuba kukho iintsuku ezingaphantsi kwe-3 de idosi yakho ehleliweyo elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo. Sukusebenzisa idosi ephindwe kabini ukwenza eyilahlekileyo.

Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso.

I-Dulaglutide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• isicaphucaphu
• isilungulela
• ukunciphisa ukutya
• ndiziva ndidiniwe

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILumkiso ESIBALULEKILEYO, yeka ukusebenzisa i-dulaglutide kwaye utsalele ugqirha kwangoko okanye ufumane unyango olungxamisekileyo:

• iintlungu eziqhubekayo eziqala phezulu ngasekhohlo okanye embindini wesisu kodwa zisenokunabela ngasemva
• ukugabha
• urhwebo
• irhashalala
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya
• ukudumba kwemilebe, ulwimi, ubuso, okanye umqala
• utshintsho lombono
• ukubetha kwentliziyo ngokukhawuleza

I-Dulaglutide inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwikhathoni yoqobo efrijini, ikhuselwe ekukhanyeni. Musa ukubanda. Ukuba kukho imfuneko, ipeni nganye yedosi ekhethiweyo inokugcinwa kubushushu begumbi ukuya kwiintsuku ezili-14. Gcina i-dulaglutide kude nokufikelela ebantwaneni.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• isicaphucaphu
• ukugabha
• Iimpawu zehypoglycemia

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Ubunzima^®