Insulin Degludec (Imvelaphi ye-rDNA) Inaliti

Umxholo

• Ngaphambi kokusebenzisa i-insulin
• Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso. I-insulin degludec inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana ezi mpawu, biza ugqirha wakho ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• I-insulin degludec overdose inokwenzeka ukuba usebenzisa kakhulu i-insulin degludec okanye ukuba usebenzisa isixa esifanelekileyo se-insulin, kodwa yitya kancinci kunesiqhelo okanye wenze umthambo ngaphezu kwesiqhelo. I-insulin degludec overdose inokubangela i-hypoglycemia. Ukuba unempawu zehypoglycemia, landela imiyalelo kagqirha wakho malunga nento ekufuneka uyenzile ukuba ukhulisa i-hypoglycemia. Ezinye iimpawu libanda:

I-insulin degludec isetyenziselwa ukunyanga isifo seswekile sokuqala (imeko apho umzimba ungayivelisi i-insulin kwaye ngenxa yoko awunakho ukulawula ubungakanani beswekile egazini). Isetyenziselwa ukunyanga abantu abanesifo seswekile sesi-2 (imeko apho umzimba ungasebenzisi i-insulin ngesiqhelo kwaye, ngenxa yoko, awunakho ukulawula isixa seswekile esegazini) abafuna i-insulin ukulawula isifo seswekile. Kwizigulana ezine-type 1 yeswekile, i-insulin degludec kufuneka isetyenziswe nolunye uhlobo lwe-insulin (i-insulin emfutshane). Kwizigulana ezinesifo seswekile sesi-2, i-insulin degludec inokusetyenziswa nolunye uhlobo lwe-insulin okanye amayeza omlomo eswekile. I-insulin degludec yinto esebenza ixesha elide, eyenziwe ngumntu ye-insulin yomntu. I-insulin degludec isebenza ngokutshintsha i-insulin edla ngokuveliswa ngumzimba nangokunceda ukuhambisa iswekile egazini iye kwezinye izicwili zomzimba apho isetyenziselwa khona amandla. Ikwanqanda isibindi ekuveliseni iswekile engaphezulu.

Ixesha elingaphezulu, abantu abanesifo seswekile kunye neswekile ephezulu yegazi banokuba neengxaki ezinzulu okanye ezisongela ubomi, kubandakanya isifo sentliziyo, ukubetha, iingxaki zezintso, ukonakala kwemithambo-luvo kunye neengxaki zamehlo. Sebenzisa amayeza, ukwenza utshintsho kwindlela yokuphila (umzekelo, ukutya, ukwenza umthambo, ukuyeka ukutshaya), kunye nokujonga iswekile yegazi rhoqo kunokunceda ukulawula isifo seswekile kunye nokuphucula impilo yakho. Olu nyango lunokunciphisa amathuba akho okuhlaselwa sisifo sentliziyo, ukubetha, okanye ezinye iingxaki ezinxulumene nesifo seswekile ezinje ngokusilela kwezintso, ukulimala kwentliziyo (ukubindeka, imilenze ebandayo okanye iinyawo; ukunciphisa amandla ezesondo kumadoda nabasetyhini), iingxaki zamehlo, kubandakanya notshintsho okanye ukulahleka kombono, okanye isifo seentsini. Ugqirha wakho kunye nabanye ababoneleli ngempilo bayakuthetha nawe ngeyona ndlela yokulawula isifo sakho seswekile.

I-insulin degludec iza njengesisombululo (ulwelo) sokufaka ngenaliti (phantsi kolusu). Itofwe kanye ngemini. Kuya kufuneka usebenzise i-insulin degludec ngaxeshanye yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa i-insulin degludec kanye njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

I-insulin degludec ilawula isifo seswekile, kodwa ayisinyangi. Qhubeka nokusebenzisa i-insulin degludec nokuba uziva uphilile. Sukuyeka ukusebenzisa i-insulin degludec ngaphandle kokuthetha nogqirha wakho. Musa ukutshintshela kolunye uphawu okanye uhlobo lwe-insulin okanye utshintshe idosi yalo naluphi na uhlobo lwe-insulin oyisebenzisayo ngaphandle kokuthetha nogqirha wakho. Ngalo lonke ixesha jonga iilebhile ye-insulin ukuze uqiniseke ukuba ufumene uhlobo olululo lwe-insulin ekhemesti.

I-insulin degludec iza kwiipeni zokufaka idosi. Qiniseka ukuba uyazi ukuba loluphi uhlobo lwesikhongozeli sakho se-insulin degludec engena kwaye zeziphi ezinye izinto, ezinjengeenaliti, kuya kufuneka ukuba utofe iyeza lakho. Qiniseka ukuba ufunda kwaye uqonde imiyalelo yomenzi. Buza ugqirha wakho okanye usokhemisti akubonise indlela yokusebenzisa usiba. Landela umkhombandlela ngononophelo, kwaye uhlale usenza uvavanyo lokhuseleko ngaphambi kokusetyenziswa.

Ungaze uphinde usebenzise iinaliti okanye iipeni. Musa ukuhambisa amayeza kwisirinji. Xa usebenzisa ipeni ye-insulin, soloko ususa inaliti emva nje kokuba utofile idosi yakho. Lahla iinaliti kunye neesirinji kwisitya esinganyangekiyo. Buza ugqirha wakho okanye usokhemesti ngendlela yokusilahla isikhongozeli esinganyangekiyo.

Musa ukungxengxeza nge-insulini yentsimbi kwaye ungayixube i-insulin kunye nolunye uhlobo lwe-insulin.

Ungayifaka i-insulin degludec yakho engalweni yakho ephezulu, ethangeni, okanye kwindawo yesisu. Ungaze ufake inaliti ye-insulin kumthambo okanye umsipha. Guqula (jikelezisa) indawo yenaliti kwindawo ekhethiweyo kunye nedosi nganye; zama ukunqanda ukujova indawo enye rhoqo kunakuqala kwiiveki ezi-1 ukuya kwezi-2.

Ngalo lonke ixesha jonga kwi-insulin yakho yentsimbi ngaphambi kokuba uyitofa. Kufuneka icace kwaye ingenambala. Sukuyisebenzisa i-insulin degludec yakho ukuba inemibala, inamafu, okanye inezinto ezomeleleyo, okanye ukuba umhla wokuphelelwa kwebhotile udlulile.

Sukusebenzisa i-insulin degludec kwimpompo yangaphandle ye-insulin.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa i-insulin

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-insulin (Humulin, Novolin, abanye), naziphi na izithako ezikwi-insulin degludec, okanye amanye amayeza. Buza usokhemesti wakho okanye ujonge ulwazi lomenzi wesigulana uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye neemveliso zamayeza owathathayo. Qiniseka ukuba ukhankanya nayiphi na kwezi zilandelayo: albuterol (Accuneb, Proair, Proventil, abanye); i-angiotensin-converting enzyme inhibitors (i-ACE inhibitors) enjenge-benazepril (Lotensin, eLotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril, lisinopril (e-Prinzide, e-Zestoretic), moexipril (Univasc, e-Univasc, e-Univasc, e-Univasc Aceon, e-Prestalia), quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), kunye trandolapril (Mavik, eTarka); ii-angiotensin receptor blockers (ARBs) ezinje nge-azilsartan (Edarbi, e-Edarbyclor), candesartan (Atacand, e-Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, eAvalide), losartan (Cozaar, e-Hyzaar), telmisartan Micard eMicardis HCT, eTwynsta), valsartan (Diovan, eDiovan HCT, e-Exforge); ii-antipsychotic ezifana ne-clozapine (Clozaril, Fazaclo, Versacloz) kunye ne-olanzapine (iZyprexa, kwi-Symbyax); ii-beta-blockers ezinjenge-atenolol (Tenormin, kwi-Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, Dutoprol, in Lopressor HCT), nadolol (Corgard, eCorzide), kunye nepropranolol (Hemangeol, Inderal LA, Innopran XL); ukunciphisa amayeza e-cholesterol afana ne-fenofibrate (Antara, Lipofen, TriCor, Triglide), gemfibrozil (Lopid), kunye ne-niacin (Niacor, Niaspan, kwi-Advicor, eSimcor); clonidine (Catapres, Catapres-TTS, Kapvay, eClorpres, abanye); idanazol; iDisopyramide (iNorpace); umchamo ('iipilisi zamanzi'); i-fluoxetine (Prozac, Sarafem, Selfemra, kwi-Symbyax); iglucagon; guanethidine; I-HIV protease inhibitors kubandakanya i-atazanavir (Reyataz, e-Evotaz), indinavir (Crixivan), lopinavir (e-Kaletra), nelfinavir (Viracept), ritonavir (Norvir, e-Kaletra, e-Viekira Pak), nase-saquinavir (Invirase); isoniazid (Laniazid, eRifamate, eRifater); lithium (Lithobid); amayeza umbefu kunye nemikhuhlane; amayeza seswekile; Unyango lwe-menopausal hormone kunye nezinto zokucwangcisa zehomoni (iipilisi zokulawula ukuzalwa, iipatches, iiringi, inaliti, okanye ukufakelwa); amayeza okugula ngengqondo kunye nesicaphucaphu; I-monoamine oxidase (MAO) inhibitors kubandakanya isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar) kunye ne-tranylcypromine (iParnate); i-octreotide (iSandostatin); i-pioglitazone (Actos, kwi-Actoplus Met, kwi-Duetact, nabanye); ipentamidine (NebuPent, Pentam); ipentoxifylline (Pentoxil); pramlintide (Symlin); ipropoxyphene (ayifumaneki e-U.S.); gqithisela; rosiglitazone (Avandia, eAvandamet, eAvandaryl); iintlungu ze-salicylate ziyancipha njenge-aspirin, i-choline magnesium trisalicylate, i-choline salicylate, i-diflunisal, i-magnesium salicylate (Doan's, abanye), kunye ne-salsalate; somatropin (Genotropin, Humatrope, Nutropin, Serostim, nabanye); ii-steroids ezinje nge-dexamethasone, methylprednisolone (Medrol), kunye ne-prednisone (iRayos); isulfa antibiotics; iterbutaline; kunye namayeza e-thyroid. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba wakhe wanomonakalo wemithambo-luvo obangelwa sisifo seswekile, okanye naziphi na ezinye iimeko zonyango, kubandakanya intliziyo, isibindi okanye isifo sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa usebenzisa i-insulin degludec, tsalela umnxeba ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba usebenzisa i-insulin degludec.
• utywala kunokubangela utshintsho iswekile yegazi. Buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kotywala ngelixa usebenzisa i-insulin degludec.
• Buza ugqirha wakho ukuba wenzeni ukuba uyagula, unengxaki yoxinzelelo engaqhelekanga, okanye utshintshe indlela otya ngayo, umthambo, okanye inkqubo yokwenza umsebenzi. Olu tshintsho lunokuchaphazela iswekile yegazi kunye nenani le-insulin oza kuyidinga.
• buza ugqirha wakho ukuba kufuneka ujonge kangaphi iswekile yegazi lakho. Yazi ukuba i-hypoglycemia inokuchaphazela amandla akho okwenza imisebenzi enjengokuqhuba kwaye ubuze ugqirha wakho ukuba ufuna ukujonga iswekile yegazi ngaphambi kokuqhuba okanye ukusebenzisa oomatshini.

Qiniseka ukuba ulandela yonke imithambo kunye nezincomo zokutya ezenziwe ngugqirha wakho okanye ugqirha otya ukutya. Kubalulekile ukutya ukutya okusempilweni kunye nokutya malunga nokulingana kweentlobo ezifanayo zokutya malunga namaxesha afanayo suku ngalunye. Ukutsiba okanye ukulibazisa ukutya okanye ukutshintsha inani okanye uhlobo lokutya okutyayo kunokubangela iingxaki kulawulo lweswekile yegazi.

Faka isitofu esilahlekileyo ngokukhawuleza nje emva kokuba usikhumbule. Nangona kunjalo, ukuba kungaphantsi kweeyure ezingama-8 ngaphambi kwethamo elilandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso. I-insulin degludec inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ubomvu, ukudumba, iintlungu, okanye ukurhawuzelela kwindawo yenaliti
• ukuqina kolusu (ukwakha amanqatha) okanye ukudakumba kancinane eluswini (ukonakala kwamanqatha)
• ukutyeba kwakho

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana ezi mpawu, biza ugqirha wakho ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• irhashalala, urticaria, okanye ukurhawuzelela umzimba wonke
• ukuvutha
• ubunzima bokuphefumla okanye ukugwinya
• ukuqhawukelwa ngumphefumlo
• ukubila
• ukudumba kwamehlo, ubuso, imilebe, ulwimi, umqala, izandla, okanye iinyawo
• ubuthathaka bemisipha

I-insulin degludec inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lingena lingenakufikelela ebantwaneni. Gcina iipeni ze-insulin ezingavulwanga kwifriji. Ungaze uvumele i-insulin degludec iqhume; Sukusebenzisa i-insulin degludec efriziwe ngumkhenkce kwaye inyibilikisiwe. I-insulin engavulwanga efrijini engagcinwanga inokugcinwa kude kube ngumhla oboniswe kwileyibhile yenkampani.

Ukuba ifriji ayifumaneki (umzekelo, xa useholideyini), gcina iipeni kubushushu begumbi, kude nelanga kunye nobushushu obukhulu ukuya kwiintsuku ezingama-56. Iipeni ezivuliweyo mazigcinwe kubushushu begumbi kwaye zinokusetyenziselwa ukuya kuthi ga kwiintsuku ezingama-56 emva kokusetyenziswa kokuqala. Lahla nayiphi na i-insulin ethe yafumana ubushushu obugqithisileyo okanye ukubanda.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

I-insulin degludec overdose inokwenzeka ukuba usebenzisa kakhulu i-insulin degludec okanye ukuba usebenzisa isixa esifanelekileyo se-insulin, kodwa yitya kancinci kunesiqhelo okanye wenze umthambo ngaphezu kwesiqhelo. I-insulin degludec overdose inokubangela i-hypoglycemia. Ukuba unempawu zehypoglycemia, landela imiyalelo kagqirha wakho malunga nento ekufuneka uyenzile ukuba ukhulisa i-hypoglycemia. Ezinye iimpawu libanda:

• ukulahleka kwengqondo
• ukuxhuzula

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Iswekile yegazi lakho kunye ne-hemoglobin eglycosylated (HbA1c) kufuneka ihlolwe rhoqo ukumisela impendulo yakho kwi-insulin degludec. Ugqirha wakho uya kukuxelela nendlela yokujonga impendulo yakho kolu nyango ngokulinganisa amanqanaba eswekile yegazi lakho ekhaya. Landela le miyalelo ngononophelo.

Kufuneka usoloko unxibe isacholo esichaza isifo seswekile ukuze uqiniseke ukuba ufumana unyango olufanelekileyo ngexesha likaxakeka. Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• UTresiba^®
• I-Ryzodeg^® (njengemveliso edibeneyo equlethe i-Insulin Degludec kunye ne-Insulin Aspart)
• Xultophy^® (njengemveliso yokudibanisa equlathe i-Insulin Degludec kunye neLiraglutide)