Rifapentine

Umxholo

• Ngaphambi kokuba uthathe i-rifapentine,
• I-Rifapentine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Rifapentine isetyenziswa namanye amayeza ukunyanga isifo sephepha esisebenzayo (i-TB; isifo esosulelayo esihlasela imiphunga kwaye ngamanye amaxesha namanye amalungu omzimba) kubantu abadala nakubantwana abaneminyaka eli-12 ubudala nangaphezulu. I-Rifapentine ikwasetyenziswa kunye ne-isoniazid (Laniazid) ukunyanga abantu abadala kunye nabantwana abaneminyaka emi-2 ubudala nangaphezulu nge-latent (ukuphumla okanye ukungalali) i-TB, kubandakanya nabo basondeleleneyo nabantu abane-TB esebenzayo, uvavanyo lwe-tuberculin lolusu oluqinisekileyo, uvavanyo lwe-immune immunodeficiency virus (HIV), okanye abo bane-pulmonary fibrosis (scarring of the lungs with a unknown cause). URifapentine ukwiklasi yamayeza abizwa ngokuba zii-antimycobacterials. Isebenza ngokubulala iintsholongwane ezibangela usulelo.

Amayeza okubulala iintsholongwane afana ne-rifapentine awusebenzi kwimikhuhlane, umkhuhlane, okanye ezinye izifo zentsholongwane. Ukusebenzisa i-antibiotics xa kungadingeki kwandisa umngcipheko wokufumana usulelo kamva oluchasayo unyango lwe-antibiotic.

I-Rifapentine iza njengecwecwe lokuthatha ngomlomo. Xa i-rifapentine isetyenziselwa ukunyanga i-TB esebenzayo, ihlala ithathwa ngokutya kabini ngeveki, kunye needosi ubuncinci iintsuku ezi-3 ukuqelelana, kwiinyanga ezimbini zokuqala kwaye kanye ngeveki iinyanga ezi-4. Xa i-rifapentine isetyenziselwa ukunyanga usulelo lwe-TB olufihlakeleyo, kufanele ukuba kube kunye nokutya okuthathwa kanye ngeveki. Thatha i-rifapentine malunga nexesha elifanayo yonke imihla emiselweyo. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-rifapentine ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ukuba awukwazi ukuginya iipilisi, ungazityumza kwaye udibanise amayeza kwinto encinci yokutya okune-semisolid njengepudding okanye iapilesauce. Ginya umxube kwangoko; sukuyigcina ukuze uyisebenzise kamva.

Qhubeka uthathe i-rifapentine de ugqibe amayeza nokuba uziva ungcono, kwaye ulumke ungaphoswa ziidosi. Ukuba uyeka ukuthatha i-rifapentine kwakamsinya, usulelo lwakho alunakunyangwa ngokupheleleyo kwaye ibacteria inokunganyangeki kwiintsholongwane. Ukuba uphosa idosi ye-rifapentine, unokuba neempawu ezingathandekiyo okanye ezimbi xa uqala ukuthatha amayeza kwakhona.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-rifapentine,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-rifapentine, i-rifabutin (i-Mycobutin), i-rifampin (i-Rifadin, i-Rimactane, i-Rifamate, i-Rifater), i-rifaximin (i-Xifaxan), nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze-rifapentine. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: amayeza okubulala iintsholongwane njenge-chloramphenicol, i-ciprofloxacin (Cipro), i-clarithromycin (i-Biaxin, kwi-Prevpac), i-dapsone, kunye ne-doxycycline (i-Doryx, i-Monodox, i-Vibramycin, nezinye); ii-anticoagulants (’izinciphisi zegazi’) ezifana ne-warfarin (Coumadin, Jantoven); ii-antifungals ezinjenge fluconazole (Diflucan), itraconazole (Onmel, Sporanox), kunye ne ketoconazole; ii-calcium channel blocker ezinje nge-diltiazem (Cardizem, Taztia, Tiazac, abanye), nifedipine (Adalat, Afeditab, Procardia), kunye ne-verapamil (Calan, Covera, Verelan); i-clofibrate (Atromid-S; ayisafumaneki e-US); icyclosporine (Gengraf, Neoral, Sandimmune); diazepam (Valium); idigoxin (Lanoxin); iDisopyramide (iNorpace); glyburide (Diabeta, Glynase); glipizide (Glucotrol); haloperidol (iHaldol); Amayeza e-HIV; levothyroxine (Levoxyl, Synthroid, Tirosint); imethadone (iDolophine, iMethadose); Mexiletine, phenobarbital; phenytoin (iDilantin, iPhenytek); uqikelelo (iRayos); ipropranolol (IHemangeol, Inderal, InnoPran); quinidine (kwiNuedexta), quinine (Qualaquin); sildenafil (Revatio, Viagra); itacrolimus (Astagraf, Envarsus, Prograf); i-theophylline (i-Elixophyllin, iTheochron, i-Uniphyl); tocainide (iTonocard; ayisafumaneki e-U.S.); kunye ne-tricyclic antidepressants ezinje nge-amitriptyline kunye ne-nortriptyline (Pamelor). Uninzi lwamanye amayeza anokusebenzisana ne-rifapentine, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba uthatha okanye usebenzisa izinto zokucwangcisa zehomoni (iipilisi zolawulo lokuzalwa, iipatches, iiringi, ukufakelwa kunye nenaliti). I-Rifapentine inokunciphisa ukusebenza kwezicwangcisi zehomoni. Kuya kufuneka usebenzise enye indlela yolawulo lokuzalwa ngelixa usela la mayeza. Thetha nogqirha wakho malunga nolawulo lokuzalwa ngelixa uthatha i-rifapentine.
• xelela ugqirha wakho ukuba une-TB esebenzayo okanye ukuba awuphenduli kwamanye amayeza e-TB okanye ukuba unayo okanye wakha wanayo i-porphyria (imeko apho izinto ezithile zendalo zakheka emzimbeni kwaye zinokubangela iintlungu zesisu, utshintsho kwindlela ocinga ngayo nakwindlela oziphatha ngayo, okanye ezinye iimpawu), usulelo lwe-HIV, okanye isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ukuba ukhulelwa ngelixa uthatha i-rifapentine, tsalela ugqirha wakho.
• Musa ukuncancisa ngelixa uthatha i-rifapentine. I-Rifapentine inokubangela ubisi lwebele ukuba lube bomvu-orenji.
• xelela ugqirha wakho ukuba unxiba iilensi zonxibelelwano ezithambileyo okanye amazinyo emboleko. I-Rifapentine inokubangela amabala abomvu asisigxina kwiilensi zakho zonxibelelwano okanye amazinyo emboleko.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Rifapentine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• Ukutshintsha kombala okwethutyana (omthubi, obomvu-orenji, okanye umbala omdaka) kulusu lwakho, amazinyo, amathe, umchamo, isitulo, ukubila kunye neenyembezi
• isiyezi
• isiqaqa
• ukwanda kokubila

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• urhudo (ukuya kuthi ga kwiinyanga ezimbini emva konyango lwakho)
• irhashalala
• ukurhawuzelela
• urhwebo
• ukhohlokhohlo
• ubunzima bokuphefumla
• obomvu, ukurhawuzelela, okanye ukucaphuka kwamehlo
• ifiva
• amadyungudyungu
• utshintsho kwindlela yokucinga neyokuziphatha
• ukudumba kwamehlo, ubuso, imilebe, ulwimi, umqala, iingalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukukhawuleza kwentliziyo okanye okungaqhelekanga
• isicaphucaphu
• ukugabha
• iintlungu zesifuba
• Iimpawu ezinje ngomkhuhlane ezinje ngomkhuhlane, ukugodola, iintlungu zemisipha, iintlungu zemisipha, ukudinwa kunye nentloko
• isisu esibuhlungu
• Ukuphelelwa ngumdla wokutya
• umchamo omnyama
• iintlungu ezidibeneyo okanye ukudumba
• mthubi ulusu okanye amehlo

I-Rifapentine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• igazi kumchamo
• ukurhawuzelela
• iintlungu zomzimba okanye ukuqina

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unokuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-rifapentine.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha i-rifapentine.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Priftin^®