Inaliti yeLixisenatide

Umxholo

• Ngaphambi kokuba uthathe inaliti ye-lixisenatide,
• Inaliti yeLixisenatide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu, yeka ukuthatha inaliti ye-lixisenatide kwaye ubize ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

Inaliti yeLixisenatide isetyenziswa kunye nokutya kunye nokuzilolonga ukunyanga isifo seswekile sesi-2 (imeko apho umzimba ungasebenzisi i-insulin ngokwesiqhelo kwaye ngenxa yoko awunakho ukulawula isixa seswekile esegazini). Inaliti yeLixisenatide ayisetyenziswanga ukunyanga isifo seswekile sokuqala (imeko apho umzimba ungayivelisi i-insulin kwaye ngenxa yoko awunakho ukulawula isixa seswekile esegazini). ILixisenatide ayisetyenziswanga endaweni ye-insulin ukunyanga abantu abanesifo seswekile abafuna i-insulin. Inaliti yeLixisenatide ikwiklasi yamayeza abizwa ngokuba yi-incretin mimetics. Isebenza ngokukhuthaza i-pancreas ukukhupha i-insulin xa amanqanaba eshukela egazi ephezulu. I-insulin inceda ukuhambisa iswekile egazini iye kwezinye izicwili zomzimba apho isetyenziselwa khona amandla. Inaliti yeLixisenatide ikwacutha ukukhutshwa kwesisu kwaye ibangele ukwehla kokutya.

Ixesha elingaphezulu, abantu abanesifo seswekile kunye neswekile ephezulu yegazi banokuba neengxaki ezinzulu okanye ezisongela ubomi, kubandakanya isifo sentliziyo, ukubetha, iingxaki zezintso, ukonakala kwemithambo-luvo kunye neengxaki zamehlo. Sebenzisa amayeza, ukwenza utshintsho kwindlela yokuphila (umzekelo, ukutya, ukwenza umthambo, ukuyeka ukutshaya), kunye nokujonga iswekile yegazi rhoqo kunokunceda ukulawula isifo seswekile kunye nokuphucula impilo yakho. Olu nyango lunokunciphisa amathuba akho okuhlaselwa sisifo sentliziyo, ukubetha, okanye ezinye iingxaki ezinxulumene nesifo seswekile ezinje ngokusilela kwezintso, ukulimala kwentliziyo (ukubindeka, imilenze ebandayo okanye iinyawo; ukunciphisa amandla ezesondo kumadoda nabasetyhini), iingxaki zamehlo, kubandakanya notshintsho okanye ukulahleka kombono, okanye isifo seentsini. Ugqirha wakho kunye nabanye ababoneleli ngempilo bayakuthetha nawe ngeyona ndlela yokulawula isifo sakho seswekile.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango ngenaliti ye-lixisenatide kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ukufumana isiKhokelo seyeza.

Inaliti yeLixisenatide iza njengepeni yedosi ekhethiweyo yokufaka inaliti (phantsi kolusu). Ihlala itofwe kanye ngemini, ngaphakathi kweyure enye (imizuzu engama-60) ngaphambi kwesidlo sokuqala sosuku. Sebenzisa inaliti ye-lixisenatide malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa inaliti ye-lixisenatide ngokuchanekileyo njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

Ugqirha wakho uya kukuqala ngedosi esezantsi ye-lixisenatide kwaye wandise idosi yakho emva kweentsuku ezili-14.

Inaliti yeLixisenatide ilawula isifo seswekile kodwa ayisinyangi. Qhubeka nokusebenzisa inaliti ye-lixisenatide nokuba uziva uphilile. Sukuyeka ukusebenzisa inaliti ye-lixisenatide ngaphandle kokuthetha nogqirha wakho.

Uya kudinga ukuthenga iinaliti ngokwahlukeneyo. Buza ugqirha wakho okanye usokhemesti ukuba loluphi uhlobo lweenaliti oza kuzidinga ukujova amayeza akho. Qiniseka ukuba uyayiqonda kwaye uyayiqonda imiyalelo yomvelisi yokutofa i-lixisenatide. Qiniseka ukuba uyazi ukuba uyicwangcisa njani kwaye nini ipeni entsha. Ukuba uyimfama okanye ungaboni kakuhle musa ukusebenzisa le peni ngaphandle koncedo. Buza ugqirha wakho okanye usokhemisti akubonise indlela yokusebenzisa usiba. Landela izikhokelo ngononophelo.

Ngalo lonke ixesha jonga isisombululo se-lixisenatide ngaphambi kokuba uyitofa. Kufuneka icace, ingenambala, kwaye ingenasuntswana. Sukusebenzisa i-lixisenatide ukuba inemibala, inamafu, iyajiya, okanye iqulethe amasuntswana aqinileyo, okanye ukuba umhla wokuphelelwa kwipeni udlulile.

Inaliti yeLixisenatide inokulawulwa ethangeni (umlenze ongasentla), isisu (indawo yesisu), okanye ingalo ephezulu. Sebenzisa indawo eyahlukileyo yenaliti nganye. Vumela usiba ukuba lufudumale kubushushu begumbi ngaphambi kokulusebenzisa ukuba lugcinwe kwisibandisi.

Ungaze uphinde usebenzise iinaliti kwaye ungaze wabelane ngeenaliti okanye iipeni. Soloko uyisusa inaliti emva kokuba utofile idosi yakho. Phonsa iinaliti kwisitya esinganyangekiyo. Buza ugqirha wakho okanye usokhemesti ngendlela yokusilahla isikhongozeli esinganyangekiyo.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe inaliti ye-lixisenatide,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-lixisenatide, i-exenatide (Bydureon, Byetta), i-liraglutide (Saxenda, i-Victoza), nawaphi na amanye amayeza, okanye naziphi na izithako kwi-lixisenatide injection. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Kubaluleke ngakumbi ukuxelela ugqirha wakho ngawo onke amayeza owathathayo ngomlomo kuba i-lixisenatide inokutshintsha indlela umzimba wakho owabamba ngayo la mayeza. Ukuba uthatha amayeza entlungu afana ne-acetaminophen (iTylenol), okanye ii-antibiotics, zithathe ubuncinci iyure enye ngaphambi kwenaliti ye-lixisenatide. Ukuba uthatha izinto zokucwangcisa ngomlomo (iipilisi zolawulo lokuzalwa) uzithathe ubuncinci iyure enye ngaphambili, okanye iiyure ezili-11 emva kokusebenzisa inaliti ye-lixisenatide. Kwakhona qiniseka ukukhankanya nawaphi na amayeza alandelayo: chlorpropamide (Diabinese), digoxin (Lanoxin), glimepiride (Amaryl, in Duetact), glipizide (Glucotrol), glyburide (DiaBeta, Glynase, in Glucovance), insulin, tolazamide, kunye itolbutamide. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba uyasela okanye wakha wasela izixa ezikhulu zotywala, okanye ukuba ukhe okanye wakha wanengxaki ezinzima zesisu, kubandakanya i-gastroparesis (ukucothisa ukuhamba kokutya ukusuka esiswini ukuya emathunjini amancinci), okanye iingxaki zokwetyisa ukutya; ukudumba kwengqondo (ukudumba kwepancreas); iinyongo (iidipozithi eziqinileyo ezenza i-gallbladder); okanye isifo sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha inaliti ye-lixisenatide, tsalela ugqirha wakho.
• buza ugqirha wakho ukuba wenzeni ukuba kukho utshintsho olukhulu kwindlela otya ngayo, umthambo, okanye ubunzima; okanye ukuba uyagula, yiba nosulelo okanye umkhuhlane, ufumane uxinzelelo olungaqhelekanga, okanye wenzakale. Olu tshintsho kunye neemeko zinokuchaphazela iswekile yegazi kunye nenani le-lixisenatide inaliti onokuyifuna.

Qiniseka ukuba ulandela yonke imithambo kunye nezincomo zokutya ezenziwe ngugqirha wakho okanye ugqirha otya ukutya. Kubalulekile ukutya ukutya okusempilweni.

Faka i-dose ephosakeleyo ngaphakathi kweyure eli-1 (imizuzu engama-60) ngaphambi kokutya kwakho okulandelayo. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukujoba idosi ephindwe kabini ukulungiselela eyilahlekileyo.

Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso.

Inaliti yeLixisenatide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• urhudo
• ukuqhina
• ukuqunjelwa
• ukudumba
• intloko ebuhlungu
• iintlungu, ukurhawuzelela, okanye ukuba bomvu kwindawo yenaliti

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu, yeka ukuthatha inaliti ye-lixisenatide kwaye ubize ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• iintlungu eziqhubekayo eziqala ngasentla ngasekhohlo okanye embindini wesisu kodwa zisenokunwenwela ngasemva, kunye okanye ngaphandle kokugabha
• urhwebo
• irhashalala
• ukurhawuzelela
• ukubetha kwentliziyo
• Ukuphelelwa ngamandla okanye ukuziva unesiyezi
• ukudumba kwamehlo, ubuso, umlomo, ulwimi, umqala, iinyawo, amaqatha okanye imilenze esezantsi
• ubunzima bokuginya okanye ukuphefumla
• ukudinwa
• ukunciphisa ukuchama,
• umlomo owomileyo kakhulu okanye ulusu okanye unxano olugqithisileyo

Inaliti yeLixisenatide inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Gcina kude nokukhanya, ubushushu, uthuli kunye nokungcola. Gcina iipeni ze-lixisenatide ezingasetyenziswanga kwifriji (36 ° F ukuya kwi-46 ° F [2 ° C ukuya kwi-8 ° C]). Nje ukuba kusetyenziswe ipeni ye-lixisenatide, yigcine kubushushu begumbi (ngaphantsi kwe-86 ° F [30 ° C]) kunye ne-cap yayo ivuliwe. Musa ukubanda. Sukusebenzisa i-lixisenatide ukuba ikhenkcisiwe. Lahla iipeni ze-lixisenatide kwisikhongozeli esinganyangekiyo emva kweentsuku ezili-14 ukusuka kusetyenziso lwayo lokuqala, nokuba kukho isisombululo esishiyekileyo ebuhlanti.

Xa useluhambeni, qiniseka ukuba ugcina iipeni ze-lixisenatide zomile. Iipeni ezingasetyenziswanga kufuneka zifriwe okanye zigcinwe kubushushu obubandayo phakathi kwe-36 ° F ukuya kwi-46 ° F (2 ° C ukuya kwi-8 ° C). Iipeni ezisetyenziswayo zingagcinwa kubushushu begumbi ukuya kuma-86 ° F [30 ° C] (hayi kwigumbi leglavu yemoto okanye kwenye indawo eshushu).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• isicaphucaphu
• ukugabha
• urhudo
• iintlungu esiswini okanye ukudumba
• ukuqunjelwa
• ukuqhina

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Iswekile yegazi lakho kunye ne-hemoglobin yeglycosylated (HbA1c) kufuneka ihlolwe rhoqo ukumisela impendulo yakho kwiliti ye-lixisenatide. Ugqirha wakho uya kukuxelela ukuba ungayijonga njani impendulo yakho kolu nyango ngokulinganisa igazi lakho okanye umchamo wamanqanaba eswekile ekhaya. Landela le miyalelo ngononophelo.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Adlyxin^®
• Soliqua^® (njengemveliso yokudibanisa equlethe i-Insulin Glargine kunye neLixisenatide)