Inaliti yeBrodalumab

Umxholo

• Ngaphambi kokusebenzisa inaliti ye-brodalumab,
• Inaliti ye-Brodalumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO okanye icandelo LOKULUMKELA OKUQHELEKILEYO, tsalela ugqirha wakho ngokukhawuleza:

Abanye abantu abasebenzisa inaliti ye-brodalumab babeneengcinga zokuzibulala kunye nokuziphatha (ukucinga ngokuzenzakalisa okanye ukuzibulala okanye ukucwangcisa okanye ukuzama ukwenza njalo). Ayaziwa ukuba inaliti ye-brodalumab ibangela iingcinga zokuzibulala kunye nokuziphatha. Xelela ugqirha wakho kunye nosokhemesti ukuba unembali yoxinzelelo okanye ukucinga ngokuzibulala. Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwaoko kwangoko: ukudakumba okutsha okanye okuba mandundu okanye uxinzelelo; iingcinga zokuzibulala, ukufa, okanye ukuzenzakalisa, okanye ukucwangcisa okanye ukuzama ukwenza njalo; utshintsho kwindlela oziphatha ngayo okanye kwimeko yakho; okanye ukwenza izinto eziyingozi. Umboneleli wakho wezempilo uya kukunika iKhadi leWallet yoMonde noluhlu lweempawu. Ukuba kukho enye yezi mpawu, kufuneka ufumane unyango ngokukhawuleza. Liphatha ikhadi ngalo lonke ixesha xa unyangwa ngenaliti ye-brodalumab, kwaye ulibonise kubo bonke ababoneleli bakho bezempilo.

Ngenxa yomngcipheko weengcinga zokuzibulala kunye nokuziphatha ngeli yeza, inaliti ye-brodalumab ifumaneka kuphela kwinkqubo ekhethekileyo ebizwa ngokuba yi-Siliq REMS^®. Wena, ugqirha wakho, kunye nekhemesti yakho kufuneka ubhalise kule nkqubo ngaphambi kokuba ufumane inaliti ye-brodalumab. Bonke abantu abamiselwe inaliti ye-brodalumab kufuneka babhalelwe ngugqirha obhaliswe kwi-Siliq REMS^® kwaye ugcwaliselwe amayeza kwikhemesti ebhaliswe kwi-Siliq REMS^® ukuze ufumane la mayeza. Buza ugqirha wakho ngolwazi oluthe kratya malunga nale nkqubo kunye nendlela oza kuwafumana ngayo amayeza akho.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango ngenaliti ye-brodalumab kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Thetha nogqirha wakho malunga neengozi zokusebenzisa inaliti ye-brodalumab.

Inaliti ye-Brodalumab isetyenziselwa ukunyanga i-plaque psoriasis (isifo solusu apho umbala obomvu, onamaxolo wenziwe kwezinye iindawo zomzimba) kubantu abane-psoriasis enzima kakhulu ukuba inganyangwa ngamayeza ezinto zodwa kwaye abangakhange banyangwe ngempumelelo amanye amayeza. Inaliti ye-Brodalumab ikudidi lwamayeza abizwa ngokuba ngamachiza omzimba. Isebenza ngokuthintela isenzo sento ethile yendalo emzimbeni ebangela iimpawu ze-psoriasis.

Inaliti yeBrodalumab iza njengamanzi kwisirinji ekhethiweyo eza kufakwa ngaphakathi (phantsi kolusu). Ihlala itofwe kanye ngeveki kwiidosi zokuqala ezi-3 kwaye kube kanye kwiiveki ezi-2. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa inaliti ye-brodalumab kanye njengoko kuyalelwe. Musa ukuyitofa ngaphezulu okanye ngaphantsi okanye uyitofe rhoqo kunokuba umiselwe ngugqirha.

Unokufaka inaliti ye-brodalumab ngokwakho okanye umhlobo okanye isizalwane senze inaliti. Ngaphambi kokuba usebenzise inaliti ye-brodalumab okokuqala, funda ngononophelo imiyalelo yomenzi. Buza ugqirha wakho okanye usokhemesti akubonise okanye umntu oza kufaka inaliti iyeza ukuba ungalitofa njani.

Sebenzisa isirinji nganye oyikhethileyo kube kanye kwaye ufake isisombululo kwisirinji. Lahla iisirinji ezisetyenzisiweyo kunye neepeni kwisitya esinganyangekiyo. Thetha nogqirha wakho okanye usokhemesti malunga nokusilahla isikhongozeli esinganyangekiyo.

Ukuba usebenzisa isirinji ekhethiweyo efrijiweyo, beka isirinji kwindawo ethe tyaba ngaphandle kokususa ikepusi yenaliti kwaye uyivumele ifudumale kubushushu begumbi malunga nemizuzu engama-30 ngaphambi kokuyisebenzisa. Sukuzama ukufudumeza amayeza ngokuwutshisa kwimicrowave, ngokuwabeka emanzini ashushu, okanye ngayo nayiphi na enye indlela. Musa ukusibuyisela isirinji kwisikhenkcisi emva kokuba sifikelele kubushushu begumbi.

Musa ukushukumisa amayeza.

Ngalo lonke ixesha jonga isisombululo se-brodalumab ngaphambi kokuba usijoje. Iyeza kufuneka licace kwaye lingenambala ukuya kumbala otyheli. Sukuyisebenzisa isirinji ukuba iyeza linamafu, libala-bala, okanye lineeflakes okanye amasuntswana.

Sukusebenzisa isirinji ukuba ilahlwe kumhlaba onzima. Inxalenye yesirinji inokuqhekeka nokuba awukwazi ukubona ikhefu.

Ungayifaka inaliti ye-brodalumab naphi na emathangeni akho (umlenze ongasentla), iingalo ezingaphezulu, okanye isisu ngaphandle kwenkaba yakho kunye nendawo eyi-intshi ezi-5 (isentimitha ezi-5) kuyo. Ukunciphisa amathuba okuqaqamba okanye ububomvu, sebenzisa indawo eyahlukileyo yenaliti nganye. Musa ukujova kwindawo apho ulusu luthambile, luchotshoziwe, lubomvu, lukhuni, luqine, lunexolo, luchaphazeleka yi-psoriasis, okanye apho uneziva okanye ukolula amanqaku.

Umboneleli wakho wezempilo angakuxelela ukuba uyeke ukusebenzisa inaliti ye-brodalumab ukuba ipsoriasis yakho ayiphuculanga kwisithuba seeveki ezili-12 ukuya kwezi-16 zonyango. Thetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa inaliti ye-brodalumab,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-brodalumab, nawaphi na amanye amayeza, okanye nasiphi na isithako esenziweyo kwisitofu se-brodalumab. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: cyclosporine (Gengraf, Neoral, Sandimmune) kunye warfarin (Coumadin, Jantoven). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokuphinda asebenzisane nenaliti ye-brodalumab, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba unesifo sikaCrohn (imeko apho amajoni omzimba ahlasela umgca wokugaya ukutya obangela iintlungu, urhudo, ukwehla kobunzima, kunye nefiva). Ugqirha wakho uya kukuxelela ukuba ungasebenzisi inaliti ye-brodalumab.
• xelela ugqirha wakho ukuba ukhe wakha wanayo na imeko yonyango.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa usebenzisa inaliti ye-brodalumab, tsalela ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba usebenzisa inaliti ye-brodalumab.
• jongana nogqirha wakho ukubona ukuba ufuna ukufumana naluphi na ugonyo. Kubalulekile ukuba zonke izitofu zokugonya zilungele iminyaka yakho ngaphambi kokuqala unyango lwakho ngenaliti ye-brodalumab. Awunalo ugonyo ngexesha lonyango ngaphandle kokuthetha nogqirha wakho.
• Kuya kufuneka uyazi ukuba inaliti ye-brodalumab inganciphisa amandla akho okulwa usulelo kwiintsholongwane, intsholongwane kunye nefungi kwaye wandise umngcipheko wokuba ufumane usulelo olubi okanye olusongela ubomi. Tshela ugqirha wakho ukuba uhlala ufumana naluphi na uhlobo losulelo okanye ukuba unayo okanye ucinga ukuba unalo naluphi na uhlobo losulelo ngoku. Oku kubandakanya usulelo oluncinci (njengokusikwa okuvulekileyo okanye izilonda), usulelo olufikayo (olufana neherpes okanye izilonda ezibandayo), kunye nosulelo olungapheliyo olungapheliyo. Ukuba ufumana naziphi na ezi mpawu zilandelayo ngexesha okanye emva nje konyango lwakho ngenaliti ye-brodalumab, biza ugqirha wakho kwangoko: umkhuhlane, ukubila, okanye ukugodola; iintlungu zemisipha; ukukhohlela; ukuqhawukelwa ngumphefumlo; umqala obuhlungu okanye ubunzima bokuginya; ukufudumala, obomvu, okanye ulusu olubuhlungu okanye izilonda emzimbeni wakho; urhudo; isisu esibuhlungu; Ukuchama rhoqo, okungxamisekileyo okanye okubuhlungu; okanye ezinye iimpawu zosulelo.
• Kuya kufuneka uyazi ukuba ukusebenzisa inaliti ye-brodalumab yonyusa umngcipheko wokuba ube nesifo sephepha (isifo sephepha; usulelo olubi lwemiphunga), ngakumbi ukuba sele wosulelwe sisifo sephepha kodwa ungenazo iimpawu zesi sifo. Xelela ugqirha wakho ukuba ukhe wakha okanye wakha wanayo na i-TB, ukuba ngaba wakhe wahlala kwilizwe apho ixhaphake kakhulu i-TB, okanye ukuba ukhe wakufutshane nomntu one-TB. Ugqirha wakho uyakukukhangela i-TB phambi kokuba aqale unyango ngenaliti ye-brodalumab kwaye anganyanga i-TB ukuba unembali ye-TB okanye une-TB esebenzayo. Ukuba unazo naziphi na kwezi mpawu zilandelayo ze-TB okanye ukuba uvela kwezi mpawu ngexesha lonyango lwakho, tsalela umnxeba kwangoko: ukukhohlela, ukukhohlela igazi okanye amafinyila, ubuthathaka okanye ukudinwa, ukwehla kobunzima, ukungabi namdla wokutya, ukugodola, umkhuhlane, okanye ukubila ebusuku.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Sebenzisa idosi ephosiweyo kwakamsinya nje emva kokuba uyikhumbule kwaye emva koko uqhubeke neshedyuli yakho yethamo yesiqhelo. Sukusebenzisa idosi ephindwe kabini ukwenza eyilahlekileyo.

Inaliti ye-Brodalumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• intlungu edibeneyo okanye yemisipha
• isicaphucaphu
• intlungu, ubomvu, ukutyumka, ukopha, okanye ukurhawuzelela kwindawo apho iyeza lafakwa khona

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO okanye icandelo LOKULUMKELA OKUQHELEKILEYO, tsalela ugqirha wakho ngokukhawuleza:

• urhudo olubuhlungu
• ilindle elinegazi
• ngequbuliso okanye ngokungalawulekiyo ukuhamba kwamathumbu
• isisu esibuhlungu okanye ukubamba
• ukuqhina
• ukuhla ukusinda

Inaliti ye-Brodalumab inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Gcina i-brodalumab iisringana ezikhethiweyo kwifriji, kodwa ungazibandisi. Gcina iisirinji kwiibhokisi zazo zoqobo ukukhusela ekukhanyeni. Xa kukho imfuneko, iisirinji ezifakwe ngaphambili zingagcinwa kubushushu begumbi ukuya kwiintsuku ezili-14. Lahla iisirinji emva kweentsuku ezili-14 kubushushu begumbi. Musa ukubeka iisirinji ezikhethiweyo ezigcinwe kwiqondo lobushushu egumbini kwakhona kwifriji.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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