Abacavir, iDolutegravir, kunye neLamivudine

Umxholo

• I-Abacavir, i-dolutegravir, kunye ne-lamivudine inokubangela ukusabela okunobungozi okanye okusongela ubomi. Biza ugqirha wakho ngokukhawuleza ukuba uvelisa uphawu olunye kumaqela amabini okanye nangaphezulu kula alandelayo ukuze ubone ukuba ufanele uyeke ukuthatha i-abacavir, i-dolutegravir kunye ne-lamivudine:
• Ngaphambi kokuba uthathe i-abacavir, i-dolutegravir, kunye ne-lamivudine,
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, okanye ezo zikhankanywe kwicandelo LESILUMKISO ESIBALULEKILEYO, tsalela ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

I-Abacavir, i-dolutegravir, kunye ne-lamivudine inokubangela ukusabela okunobungozi okanye okusongela ubomi. Biza ugqirha wakho ngokukhawuleza ukuba uvelisa uphawu olunye kumaqela amabini okanye nangaphezulu kula alandelayo ukuze ubone ukuba ufanele uyeke ukuthatha i-abacavir, i-dolutegravir kunye ne-lamivudine:

• Iqela 1: umkhuhlane
• Iqela 2: ukukhawuleza
• Iqela lesi-3: isicaphucaphu, ukugabha, urhudo, okanye indawo yesisu
• Iqela lesi-4: ukugula ngokubanzi, ukudinwa kakhulu, okanye ukonwaba
• Iqela lesi-5: ukuphefumla kancinci, ukukhohlela, okanye umqala obuhlungu

Kwakhona, biza ugqirha wakho ngokukhawuleza ukuba unazo naziphi na kwezi mpawu zilandelayo: intloko ebuhlungu; iintlungu zemisipha okanye ngokudibeneyo; ukudumba kobuso, izandla, iinyawo, amaqatha okanye imilenze esezantsi; iintlungu, ukutshisa, okanye ukubetha ezandleni nasezinyaweni; ukurhawuzelela; ukudumba okanye ukuxobuka kolusu; ubunzima bokuginya okanye ukuphefumla; obomvu, ukudumba, ukurhawuzelela, okanye ukulila; okanye izilonda emlonyeni.

Usokhemesti wakho uya kukunika ikhadi lesilumkiso xa ufumana amayeza oza kuwathwala. Ikhadi lesilumkiso linamaqela eempawu ezidweliswe apha ngasentla ukwenza ukuba kube lula kuwe nakubantu abakungqongileyo ukuba uqaphele ukuba unengxaki yokungavumi. Qiniseka ukuba uyiphethe leKhadi leSilumkiso ngawo onke amaxesha.

Abanye abantu banokuba semngciphekweni wokungabikho komzimba kwi-abacavir, i-dolutegravir, kunye ne-lamivudine ngokusekwe kwilifa labo okanye ukwakheka kwemfuza. Ugqirha wakho unoku-odola uvavanyo lweelebhu zemfuza ngaphambi kokuqala i-abacavir, i-dolutegravir, kunye ne-lamivudine okanye ukuba awuzange kuvavanywe ngaphambili ukufumanisa ukuba ngaba kunokwenzeka ukuba ube neempendulo ezichaseneyo nala mayeza. Tshela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-abacavir, i-dolutegravir, kunye ne-lamivudine okanye nawaphi na amayeza aqukethe i-abacavir okanye i-dolutegravir okanye ukuba uyazi ukuba unayo loo mfuza.Ukuba ukhe wakha wadibana ne-abacavir (e-Epzicom, eTrizivir, Ziagen) okanye i-dolutegravir (Tivicay) okanye naliphi na iyeza eline-abacavir okanye i-dolutegravir, ugqirha wakho uya kuthi mhlawumbi ungathathi i-abacavir, i-dolutegravir kunye ne-lamivudine. Ukuba ugqirha ukuxelela ukuba uyeke ukuthatha i-abacavir, i-dolutegravir, kunye ne-lamivudine ngenxa yokuba une-allergical reaction, ungaze uthathe i-abacavir, i-dolutegravir, kunye ne-lamivudine okanye iyeza eliqukethe i-abacavir okanye i-dolutegravir kwakhona. Ukuba uyeka ukuthatha i-abacavir, i-dolutegravir, kunye ne-lamivudine ngaso nasiphi na esinye isizathu, kubandakanya ukulahleka kweedosi ezininzi ngokulandelelana okanye ukuphelelwa ngamayeza, ungaqali ukuyithatha ungakhange uqale uthethe nogqirha wakho. Uya kudinga ukuba ube phakathi kwabantu abanokubonelela okanye abafowunele ukhathalelo lonyango olungxamisekileyo, ukuba luyimfuneko, xa uqala kwakhona eli yeza.

Tshela ugqirha wakho ukuba unayo okanye ucinga ukuba unokuba nosulelo lwe-virus ye-hepatitis B (HBV; usulelo oluqhubekayo lwesibindi) okanye usulelo lwentsholongwane ye-hepatitis C (HCV; usulelo lwesibindi oluqhubekayo). Ukuba unayo i-HBV kwaye uthatha i-abacavir, i-dolutegravir, kunye ne-lamivudine, imeko yakho inokuba mandundu mandundu xa uyeka ukuthatha i-abacavir, i-dolutegravir kunye ne-lamivudine. Ugqirha wakho uyakukuvavanya kwaye aodole uvavanyo lwelebhu rhoqo kwiinyanga ezininzi emva kokuba uyekile ukuthatha i-abacavir, i-dolutegravir, kunye ne-lamivudine ukubona ukuba i-HBV yakho iye yaba mbi na.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwi-abacavir, i-dolutegravir, kunye ne-lamivudine.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-abacavir, i-dolutegravir, kunye ne-lamivudine kwaye ngalo lonke ixesha uzalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-abacavir, i-dolutegravir kunye ne-lamivudine.

Indibaniselwano ye-abacavir, i-dolutegravir, kunye ne-lamivudine isetyenziswa yodwa okanye kunye namanye amayeza ukunyanga usulelo lwe-HIV kubantu abadala abathile nabantwana abanobunzima obungama-88 lb (40 kg). I-Abacavir kunye ne-lamivudine bakudidi lwamayeza abizwa ngokuba yi-nucleoside analogue reverse transcriptase inhibitors (NRTIs) kunye ne-dolutegravir ikudidi lwamayeza abizwa ngokuba yi-integrase strand transfer inhibitors (INSTIs). Zisebenza ngokunciphisa inani le-HIV egazini lakho kwaye zonyusa inani leeseli zomzimba ezinceda ukulwa usulelo emzimbeni wakho. Nangona i-abacavir, i-dolutegravir, kunye ne-lamivudine zingayi kuyinyanga i-HIV, la mayeza angalinciphisa ithuba lakho lokufumana isifo se-immunodeficiency syndrome (i-AIDS) kunye nezifo ezinxulumene ne-HIV ezinje ngezifo ezinzulu okanye umhlaza. Ukuthatha la mayeza kunye nokwabelana ngesondo okukhuselekileyo nokwenza olunye utshintsho kwindlela yokuphila kunokunciphisa umngcipheko wokufumana okanye wokuhambisa intsholongwane kaGawulayo kwabanye abantu.

Indibaniselwano ye-abacavir, i-dolutegravir, kunye ne-lamivudine iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye yonke imihla kunye okanye ngaphandle kokutya. Thatha i-abacavir, i-dolutegravir, kunye ne-lamivudine ngexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-abacavir, i-dolutegravir, kunye ne-lamivudine kanye njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

I-Abacavir, i-dolutegravir, kunye ne-lamivudine zinceda ukulawula usulelo lwe-HIV kodwa alulunyangi. Qhubeka uthathe i-abacavir, i-dolutegravir, kunye ne-lamivudine nokuba uziva uphilile. Sukuyeka ukuthatha i-abacavir, i-dolutegravir, kunye ne-lamivudine ngaphandle kokuthetha nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-abacavir, i-dolutegravir, kunye ne-lamivudine,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-abacavir, i-dolutegravir, kunye ne-lamivudine, nawaphi na amanye amayeza, okanye nasiphi na isithako se-abacavir, i-dolutegravir kunye neepilisi ze-lamivudine. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha i-dofetilide (Tikosyn). Ugqirha wakho uya kukuxelela ukuba ungathathi i-abacavir, i-dolutegravir, kunye ne-lamivudine ukuba uthatha eli yeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, othabathayo okanye oceba ukuthatha Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: carbamazepine (Carbatrol, Equetro, Tegretol, nabanye); dalfampridine (Ampyra); amanye amayeza e-HIV kubandakanya abacavir (e-Epzicom, e-Trizivir, Ziagen), dolutegravir (Tivicay), efavirenz (Sustiva, e-Atripla), emtricitabine (Emtriva, e-Atripla, e-Complera, e-Truvada, abanye), etravirine (Intelence), fosamprenavir (Lexiva) ethathwe nge-ritonavir (Norvir), lamivudine (Epivir, e-Combivir, e-Epzicom, e-Trizivir, abanye), nevirapine (Viramune), kunye ne-tipranavir (Aptivus) ethathwe nge-ritonavir (Norvir); metformin (iGlumetza, iGlucophage, iRiomet); imethadone (iDolophine, iMethadose); i-oxcarbazepine (iOxtellar XR, iTrileptal); phenobarbital; phenytoin (iDilantin, iPhenytek); irifampin (Rifadin, Rimactane, eRifamate, eRifater); kunye ne-sorbitol okanye amayeza aqukethe i-sorbitol. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• ukuba uthatha ii-antacids, laxatives, okanye ii-multivitamini ezine-aluminium, i-magnesium, okanye i-calcium; izongezo zekhalsiyam; izongezo zentsimbi; I-sucralfate (iKarafate); okanye amayeza axineneyo anjenge-aspirin ethandwayo, thatha i-abacavir, i-dolutegravir, kunye ne-lamivudine ubuncinci iiyure ezi-2 ngaphambili okanye iiyure ezingama-6 emva kokuba uthathe la mayeza.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort. Akufanele uthathe i-wort yaseSt.John ngelixa uthatha i-abacavir, i-dolutegravir, kunye ne-lamivudine.
• xelela ugqirha wakho ukuba ukhe unesifo sesibindi. Ugqirha wakho uyakukuxelela ukuba ungathathi i-abacavir, i-dolutegravir kunye ne-lamivudine.
• xelela ugqirha wakho ukuba uyatshaya okanye uyasela utywala, okanye ukuba ubukhe wanalo uxinzelelo lwegazi oluphezulu, icholesterol ephezulu, isifo seswekile, okanye isifo sentliziyo okanye sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Uya kudinga ukuthatha uvavanyo lokukhulelwa ngaphambi kokuba uqale unyango. Akufanele ukhulelwe ngelixa uthatha i-abacavir, i-dolutegravir, kunye ne-lamivudine. Thetha nogqirha wakho malunga neendlela ezifanelekileyo zolawulo lokuzalwa onokuzisebenzisa ngexesha lonyango lwakho. Ukuba ukhulelwa ngelixa uthatha i-abacavir, i-dolutegravir, kunye ne-lamivudine, tsalela ugqirha ngokukhawuleza. I-Dolutegravir inokwenzakalisa umntwana ongekazalwa.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncancise xa wosulelwe yi-HIV okanye ukuba uthatha i-abacavir, i-dolutegravir, kunye ne-lamivudine.
• buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kotywala kunye namayeza aqukethe utywala ngelixa uthatha i-abacavir, i-dolutegravir kunye ne-lamivudine.
• Kuya kufuneka uyazi ukuba ngelixa uthatha amayeza ukunyanga usulelo lwe-HIV, amajoni akho omzimba angomelela kwaye aqale ukulwa nezinye izifo ezazisele zisemzimbeni wakho. Oku kunokubangela ukuba ube neempawu zolu sulelo. Ukuba uneempawu ezintsha okanye ezibaxekileyo nanini na ngexesha lonyango lwakho nge-abacavir, i-dolutegravir, kunye ne-lamivudine, qiniseka ukuxelela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, okanye ezo zikhankanywe kwicandelo LESILUMKISO ESIBALULEKILEYO, tsalela ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ukudinwa okugqithisileyo; ubuthathaka, isiyezi, okanye iintloko; ukukhawuleza kwentliziyo okanye okungaqhelekanga; iintlungu zemisipha; isisu esibuhlungu isicaphucaphu nokugabha; ukuphefumla kancinci okanye ukuphefumla nzima; iimpawu ezinjengomkhuhlane ezifana nomkhuhlane, ukugodola, okanye ukukhohlela; okanye uziva ubanda, ngakumbi ezingalweni okanye emilenzeni
• ukukhanya okukhanyayo; ubumthubi besikhumba okanye amehlo; ukuphelelwa ngumdla wokutya; ukopha okungaqhelekanga okanye ukugruzuka; umchamo omnyama omthubi okanye omdaka; okanye iintlungu kwinxalenye ephezulu yesisu

I-Abacavir, i-dolutegravir, kunye ne-lamivudine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Musa ukuyisusa i-desiccant (ipakethi encinci ebandakanyiwe kunye namayeza okufunxa ukufuma) kwibhotile yakho.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Gcina unikezelo lwe-abacavir, i-dolutegravir, kunye ne-lamivudine esandleni. Sukulinda de uphelelwe ngamayeza ukuze uphinde uzalise amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Triumeq^®