Inaliti ye-Aprepitant / Fosaprepitant

Umxholo

• Ngaphambi kokusebenzisa inaliti ye-aprepitant okanye fosaprepitant,
• Inaliti ye-aprepitant kunye ne-fosaprepitant inaliti inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

Inaliti ye-aprepitant kunye ne-fosaprepitant injection zisetyenziswa kunye namanye amayeza ukuthintela isicaphucaphu kunye nokugabha kubantu abadala ezinokuthi zenzeke ngaphakathi kweeyure ezingama-24 okanye kwiintsuku ezininzi emva kokufumana unyango oluthile lomhlaza wekhemotherapy.Inaliti yeFosaprepitant inokusetyenziswa nakubantwana kwiinyanga ezi-6 ubudala nangaphezulu. Inaliti ye-Aprepitant kunye ne-fosaprepitant yile hayi Isetyenziselwa ukunyanga isicaphucaphu nokugabha osele unako. Inaliti ye-aprepitant kunye ne-fosaprepitant ikudidi lwamayeza abizwa ngokuba yi-antiemetics. Basebenza ngokuthintela isenzo se-neurokinin, into yendalo kwingqondo ebangela isicaphucaphu nokugabha.

Inaliti ye-Aprepitant iza njenge-emulsion (ulwelo) kwaye inaliti yefosaprepitant iza njengomgubo wokudityaniswa nolwelo kwaye inikwe ngaphakathi (emthanjeni) ngugqirha okanye ngumongikazi kwiziko lonyango. Inaliti ye-aprepitant okanye inaliti ye-fosaprepitant ihlala inikwa njengedosi yexesha elinye ngosuku 1 lomjikelo wonyango lwe-chemotherapy, ugqibe malunga nemizuzu engama-30 ngaphambi kokuqala kwe-chemotherapy. Kubantwana nakwishumi elivisayo abafumana inaliti ye-aprepitant kunye nabantu abadala abafumana i-fosaprepitant ngonyango oluthile lwe-chemotherapy, i-aprepitant yomlomo inokunikwa ngeentsuku ze-2 kunye ne-3 yomjikelo wonyango lwe-chemotherapy.

Unokufumana impendulo ngexesha okanye kungekudala emva kokuba ufumene idosi yenaliti ye-aprepitant okanye inaliti ye-fosaprepitant. Xelela ugqirha wakho kwangoko ukuba unazo naziphi na kwezi mpawu ngexesha okanye kungekudala emva kokuba ufumene unyango: ukudumba ujikeleze amehlo akho, irhashalala, urhashalala, ukurhawuzelela, ukuba bomvu, ukugungxula, ukuphefumla nzima okanye ukugwinya, ukuziva udizzy okanye utyhafile, okanye ukhawuleze okanye ubethe intliziyo. Ugqirha wakho uya kuyeka ukumnika, kwaye unokunyanga impendulo ngamanye amayeza.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa inaliti ye-aprepitant okanye fosaprepitant,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-fosaprepitant, i-aprepitant, nawaphi na amanye amayeza, okanye naziphi na izithako kwi-aprepitant injection okanye i-fosaprepitant injection. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha ipimozide (Orap). Ugqirha wakho uya kukuxelela ukuba ungasebenzisi iaprepitant okanye fosaprepitant inaliti ukuba uthatha eli yeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-anticoagulants ('i-blood thinner') efana ne-warfarin (Coumadin, Jantoven); ii-antifungals ezithile ezinje nge-itraconazole (Onmel, Sporanox) kunye ne-ketoconazole; i-benzodiazepines ezifana ne-alprazolam (Xanax), midazolam, kunye ne-triazolam (Halcion); amayeza athile omhlaza womhlaza onje nge-ifosfamide (Ifex), vinblastine (Velban), kunye ne-vincristine (Marqibo); carbamazepine (Tegretol, Teril, nabanye); i-clarithromycin (i-Biaxin, kwi-Prevpac); diltiazem (Cardizem, Cartia, Diltzac, nabanye); inhibitors ezithile ze-HIV ezifana ne-nelfinavir (i-Viracept) kunye ne-ritonavir (i-Norvir, e-Kaletra, e-Technivie, e-Viekira Pak); nefazodone; ii-steroids ezinje nge-dexamethasone kunye ne-methylprednisolone (Depo-medrol, Medrol, Solu-medrol); phenytoin (iDilantin, iPhenytek); kunye nerifampin (Rifadin, Rimactane, eRifamate, Rifater). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-aprepitant kunye ne-fosaprepitant, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba ukhe unesifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba usebenzisa izinto zokucwangcisa zehomoni (iipilisi zolawulo lokuzalwa, iipatches, iiringi, ukufakelwa, okanye inaliti) ngexesha lonyango ngeaprepitant okanye fosaprepitant kuya kufuneka usebenzise enye indlela engeyiyohormonal yolawulo lokuzalwa (spermicide, ikhondomu) ukunqanda ukukhulelwa ngexesha lonyango ngeaprepitant okanye fosaprepitant kunye nenyanga e-1 emva kwedosi yakho yokugqibela. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Ukuba ukhulelwa ngelixa usebenzisa i-aprepitant okanye i-fosaprepitant injection, biza ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Inaliti ye-aprepitant kunye ne-fosaprepitant inaliti inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukudinwa okanye ubuthathaka
• urhudo
• iintlungu, ukuba bomvu, ukurhawuzelela, ubunzima, okanye ukudumba kwindawo yenaliti
• ubuthathaka, ukuphazamiseka, ukubetha, okanye iintlungu kwiingalo okanye emilenzeni
• intloko ebuhlungu
• isilungulela

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• ukuxobuka okanye ukudumba kolusu
• Ukuchama rhoqo okanye okubuhlungu, ngequbuliso kufuneka uchame ngoko nangoko

I-Aprepitant kunye ne-fosaprepitant inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina lonke ixesha lokudibana nogqirha wakho.

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• ICinvanti^®
• Hlaziya^®