Acalabrutinib

Umxholo

• Ngaphambi kokuba uthathe i-acalabrutinib,
• I-Acalabrutinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu yeka ukuthatha i-acalabrutinib kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

I-Acalabrutinib isetyenziselwa ukunyanga abantu abane-mantle cell lymphoma (i-MCL; umhlaza okhula ngokukhawuleza oqala kwiiseli zamasosha amajoni omzimba) esele zinyangiwe ngamanye amayeza e-chemotherapy. Isetyenziswa sodwa okanye nge-obinutuzumab (Gazyva) ukunyanga i-lymphocytic leukemia (CLL; uhlobo lomhlaza oqala kwiiseli ezimhlophe zegazi) kunye ne-lymphocytic lymphoma (SLL: uhlobo lomhlaza oqala kwiiseli ezimhlophe zegazi) . I-Acalabrutinib ikwiklasi yamayeza abizwa ngokuba yi-kinase inhibitors. Isebenza ngokuthintela isenzo seprotein engaqhelekanga ebonisa iiseli zomhlaza ukuba zande. Oku kunceda ukunqanda ukusasazeka kweeseli zomhlaza.

I-Acalabrutinib iza njengephilisi ukuyithatha ngomlomo. Kuhlala kuthathwa kunye okanye ngaphandle kokutya rhoqo kwiiyure ezili-12 (kabini ngemini) ixesha elide ugqirha ecebisa ukuba ufumane unyango. Thatha i-acalabrutinib kumaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-acalabrutinib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Gwinya zonke njengezingxobo ngeglasi yamanzi; musa ukuzivula, uzihlafune, okanye uzaphule.

Ugqirha wakho unokuyeka okwethutyana okanye ngokusisigxina unyango lwakho okanye unciphise idosi yakho ye-acalabrutinib kuxhomekeke kwiziphumo ozifumanayo. Qiniseka ukuba uthetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho. Ungayeki ukuthatha i-acalabrutinib ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-acalabrutinib,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-acalabrutinib, nawaphi na amanye amayeza, okanye naziphi na izithako kwiicapsabalutinib Buza usokhemesti wakho okanye ujonge uLwazi lweZigulana uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ngokukhankanya amayeza e-anticoagulant ('igazi elincinci') njengewarfarin (Coumadin); amayeza e-antiplatelet ('igazi elincinci') njenge-aspirin, i-cilostazol, i-clopidogrel (i-Plavix), i-dipyridamole (i-Persantine, kwi-Aggrenox), i-prasugrel (i-Effient), i-ticagrelor (i-Brilinta) kunye ne-ticlodipine; diltiazem (Cardizem, Cartia, Diltzac, nabanye); erythromycin (EES, Eryc, Erythrocin, abanye); i-fluconazole (iDiflucan); itraconazole (Onmel, Sporanox); Iiproton pump inhibitors ezifana ne-dexlansoprazole (Dexilant), esomeprazole (Nexium, eVimovo), lansoprazole (Prevacid, e-Prevpac), omeprazole (Prilosec, e-Yosprala, Zegerid), pantoprazole (Protonix), kunye ne-rabeprazole (Aciphex) kunye nerifampin (Rifadin, Rimactane, eRifater, Rifamate). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-acalabrutinib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• ukuba uthatha i-cimetidine (Tagamet), i-famotidine (i-Pepcid, kwi-Duexis), i-nizatidine (i-Axid), okanye i-ranitidine (i-Zantac) ithatha i-acalabrutinib ubuncinci iiyure ezi-2 ngaphambi kokuthatha la mayeza.
• ukuba uthatha ii-antacids (Maalox, Mylanta, Tums, others) thatha i-acalabrutinib ubuncinci iiyure ezi-2 ngaphambi okanye emva kokuthatha la mayeza.
• xelela ugqirha wakho ukuba unentsholongwane okanye uqhaqho kutshanje, okanye ukuba unesifo sesibindi kubandakanya hepatitis B, iingxaki kwisingqi sentliziyo, okanye iingxaki zokopha.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Akufanele ukhulelwe ngelixa uthatha i-acalabrutinib. Akufanele uqale ukuthatha i-acalabrutinib de kube uvavanyo lokukhulelwa lubonise ukuba awukhulelwe kwaye kuya kufuneka usebenzise ulawulo lokuzalwa ukuthintela ukukhulelwa ngexesha lonyango lwakho kwaye ubuncinci iveki enye emva kwedosi yakho yokugqibela. I-Acalabrutinib inokulimaza usana lwakho olungekazalwa. Ukuba ukhulelwa ngelixa uthatha i-acalabrutinib, biza ugqirha ngokukhawuleza.
• xelela ugqirha wakho ukuba uncelisa. Ugqirha wakho unokukuxelela ukuba ungancancisi ngexesha lonyango lwakho kunye nakwiiveki ezi-2 emva kwedosi yakho yokugqibela.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-acalabrutinib. Ugqirha wakho unokukuxelela ukuba uyeke ukuthatha i-acalabrutinib kangangexesha elithile ngaphambi nasemva kotyando okanye inkqubo.
• cwangcisa ukuthintela ukukhanya elangeni ngokungeyomfuneko okanye ixesha elide kunye nokunxiba impahla ekhuselayo, iiglasi zelanga kunye nescreen selanga. I-Acalabrutinib inokwenza ulusu lwakho lubonakale kwimiphumela eyingozi yelanga, kwaye inokunyusa umngcipheko wokuba nomhlaza wolusu.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yamagilebhisi ngelixa uthatha eli yeza.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba ngaphezulu kweeyure ezintathu sele kudlulile ukusukela idosi ephosiweyo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Acalabrutinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• isicaphucaphu
• ukugabha
• ukuqhina
• urhudo
• intlungu zesisu
• irhashalala
• ukutyumka ukukhanya okanye iindawo ezincinci ezibomvu okanye ezimfusa eluswini
• intlungu edibeneyo okanye yemisipha
• ukudinwa kakhulu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu yeka ukuthatha i-acalabrutinib kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

• umkhuhlane, umqala obuhlungu, ingqele, okanye ezinye iimpawu zosulelo
• ukukhohlela, ukuphefumla kancinci, iintlungu esifubeni xa uphefumla okanye ukhohlela, umkhuhlane
• ukukhawuleza kwentliziyo okanye okungaqhelekanga, ukubetha, ukuziva unentloko okanye udizzy, ukuphelelwa amandla, ukuphefumula okufutshane, iintlungu zesifuba
• ukopha okungaqhelekanga okanye ukuqina
• igazi kwizitulo zakho okanye emnyama, ilindle; umchamo opinki okanye omdaka; ukugabha igazi okanye umhlaba wekhofi; ukhohlela igazi
• Ukuziva unesiyezi, ubuthathaka, okanye udidekile; utshintsho kwintetho; Intloko ehlala ixesha elide

I-Acalabrutinib inokunyusa umngcipheko wokuphuhlisa ezinye i-cancer. Thetha nogqirha wakho malunga nemingcipheko yokuthatha la mayeza.

I-Acalabrutinib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-acalabrutinib.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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