Pegvaliase-pqpz Inaliti

Umxholo

• Ngaphambi kokusebenzisa inaliti ye-pegvaliase-pqpz,
• Inaliti yePegvaliase-pqpz inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILumkiso ESIBALULEKILEYO, yeka ukusebenzisa inaliti ye-pegvaliase-pqpz kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

Inaliti yePegvaliase-pqpz inokubangela ukusabela okunobuzaza okanye okusongela ubomi. Ezi mpendulo zinokwenzeka kungekudala emva kwenaliti yakho okanye nangaliphi na ixesha kunyango lwakho. Idosi yokuqala kufuneka inikezwe ngugqirha okanye umongikazi kwindawo yokhathalelo lwempilo apho ezi mpendulo zinokunyangwa kwaye apho unokujongwa khona ngokusondeleyo kangangeyure enye emva kwenaliti. Ugqirha wakho unokukunika amayeza athile ngaphambi kokuba ufumane inaliti ye-pegvaliase-pqpz ukunceda ukuthintela impendulo. Ugqirha wakho uya kukunika isixhobo se-epinephrine esinezixhobo esizenzekelayo (i-Adrenaclick, i-Auvi-Q, i-EpiPen, nabanye) ukunyanga impendulo esongela ubomi. Ugqirha wakho uya kukufundisa kunye nomkhathaleli wakho ukuba ulisebenzisa njani eli nyango kunye nendlela yokuqonda imiqondiso yokuphendula komzimba. Yiphathe inaliti ye-epinephrine ngamaxesha onke. Ukuba ufumana naziphi na kwezi mpawu zilandelayo nangaliphi na ixesha kunyango lwakho, sebenzisa inaliti ye-epinephrine kwaye ufumane unyango olukhawulezileyo: ubunzima bokuginya okanye ukuphefumla; ukuqhawukelwa ngumphefumlo; ukuvutha; ukudakumba; ukudumba kobuso, umqala, ulwimi okanye imilebe; imihlathi ukugungxula okanye ukuba bomvu ngequbuliso kobuso, intamo okanye isifuba esingaphezulu; irhashalala; ukurhawuzelela; ukuba bomvu kwesikhumba; isiqaqa; isiyezi; iintlungu esifubeni okanye ukungaphatheki kakuhle; ukuqina komqala okanye isifuba; ukugabha; isicaphucaphu; urhudo; okanye ukulahleka kolawulo lwesinyi.

Ngenxa yomngcipheko ngeli chiza, inaliti ye-pegvaliase-pqpz ifumaneka kuphela ngenkqubo ekhethekileyo yokuhambisa ethintelweyo ebizwa ngokuba yiPalynziq^® Inkqubo yokuVavanya iRisk kunye neNkqubo yokuCwangcisa yokuNciphisa (REMS). Wena, ugqirha wakho kunye nosokhemesti kufuneka ubhalise kule nkqubo ngaphambi kokuba ufumane inaliti ye-pegvaliase-pqpz. Buza ugqirha wakho ukuba unemibuzo malunga nokuba uza kuwafumana njani amayeza akho.

Umboneleli wakho wezempilo uya kukunika iPalynziq^® ikhadi lokhuseleko lomguli elichaza iimpawu zokungabikho komzimba onokuba nazo ngeli liyeza. Phatha eli khadi ngamaxesha onke ngexesha lonyango lwakho. Kubalulekile ukubonisa iPalynziq yakho^® ikhadi lokhuseleko lomguli kuye nawuphi na umboneleli wezempilo okunyangayo.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zelebhu ngaphambi kwaye ngexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwisitofu se-pegvaliase-pqpz.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango ngenaliti ye-pegvaliase-pqpz kwaye ngalo lonke ixesha ufumana iyeza. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Inaliti yePegvaliase-pqpz isetyenziswa kunye nokutya okuthile ukunciphisa amanqanaba egazi le-phenylalanine kubantu abane-phenylketonuria (PKU; imeko yokuzalwa apho i-phenylalanine inokwakha egazini kwaye ibangele ukwehla kobukrelekrele kunye nokwehla kokujonga, khumbula, kunye cwangcisa ulwazi) kwaye ngubani ongalawulekiyo kumanqanaba egazi e-phenylalanine. Inaliti yePegvaliase-pqpz ikudidi lwamayeza abizwa ngokuba zii-enzymes. Isebenza ngokunceda ukunciphisa inani le-phenylalanine emzimbeni.

Inaliti ye-Pegvaliase-pqpz iza njengesisombululo (ulwelo) sokufaka ngenaliti (phantsi nje kwesikhumba). Ihlala itofwe kanye ngeveki iiveki ezi-4, kwaye inyuke ngokuthe chu kwiiveki ezi-5 ezizayo kube kanye yonke imihla. Ugqirha wakho uya kutshintsha idosi yakho ngokusekwe kwimpendulo yomzimba wakho kunyango. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa i-pegvaliase-pqpz inaliti ngokuchanekileyo njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

Ngaphambi kokuba usebenzise inaliti ye-pegvaliase-pqpz, jonga isisombululo kufutshane. Iyeza kufuneka licace mthubi mthubi kwaye lingenazinto zidadayo. Ukuba iyeza linamafu, libala, okanye liqulathe amasuntswana, musa ukuwasebenzisa. Musa ukushukumisa isirinji ekhethiweyo.

Unokufaka inaliti ye-pegvaliase-pqpz ngaphambili kwamathanga akho okanye naphina esiswini sakho ngaphandle kwenkaba yakho (iqhosha lesisu) kunye nendawo eyi-intshi ezi-2 ezijikeleze yona. Ukuba omnye umntu utofa iyeza lakho, umphezulu weempundu kunye nommandla ongaphandle weengalo ezingaphezulu unokusetyenziswa. Musa ukulifaka iyeza eluswini elithambileyo, elityumkileyo, elibomvu, elilukhuni, okanye elingapheliyo, okanye elinamanxeba, iincukuthu, iitattoos, okanye imivumbo. Khetha indawo eyahlukileyo ngalo lonke ixesha utofa iyeza, ubuncinci ii-intshi ezimbini ukusuka kwindawo obukhe wayisebenzisa ngaphambili. Ukuba ngaphezulu kwenaliti enye iyafuneka kwidosi enye, iisayithi zokutofa kufuneka okungenani zibe zi-intshi ezi-2 kude enye kwenye kodwa zingabakwicandelo elinye lomzimba okanye kwelinye icandelo lomzimba.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa inaliti ye-pegvaliase-pqpz,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-pegvaliase, nawaphi na amanye amayeza, okanye nasiphi na isithako se-pegvaliase-pqpz. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya oku kulandelayo: amanye amayeza e-PEGylated anje ngegriseofulvin (Gris-Peg), medroxyprogesterone (Depo-Provera, kwabanye), okanye amayeza e-peg-interferon (Pegasys, Peg-Intron, Sylatron, abanye). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa usebenzisa inaliti ye-pegvaliase-pqpz, tsalela ugqirha wakho.

Landela isicwangciso sakho sokutya ngononophelo. Ugqirha wakho uya kubeka esweni inani leeprotein kunye ne-phenylalanine oyityayo noselayo ngexesha lonyango lwakho.

Ukuba idosi ilahlekile, jofa idosi yakho elandelayo njengoko kucwangcisiwe. Sukujoba idosi ephindwe kabini ukulungiselela eyilahlekileyo.

Inaliti yePegvaliase-pqpz inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ububomvu, ukurhawuzelela, iintlungu, ukugruzuka, irhashalala, ukudumba, ukuthamba kwindawo yenaliti
• intlungu edibeneyo
• intloko ebuhlungu
• isisu esibuhlungu
• umlomo nomqala obuhlungu
• ndiziva ndidiniwe
• ixhala
• ukulahleka kweenwele

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILumkiso ESIBALULEKILEYO, yeka ukusebenzisa inaliti ye-pegvaliase-pqpz kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

• irhashalala, ukurhawuzelela, imingxunya, okanye bomvu ulusu oluhlala ubuncinci iintsuku ezili-14

Inaliti yePegvaliase-pqpz inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli elingene ukukhusela ekukhanyeni, livale ngci, kwaye lingenakufikelela ebantwaneni. Gcina kwifriji; sukuma ngumkhenkce. Ikwagcinwa kubushushu begumbi ukuya kwiintsuku ezingama-30. Xa iyeza ligcinwe kubushushu begumbi, musa ukulibuyisela kwifriji.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Palynziq^®