I-Tagraxofusp-erzs Inaliti

Umxholo

• Ngaphambi kokufumana i-tagraxofusp-erzs,
• I-Tagraxofusp-erzs inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILumkiso ESIBALULEKILEYO tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

Inaliti yeTagraxofusp-erzs inokubangela ukusabela okungathandekiyo nokusongela ubomi okubizwa ngokuba yi-capillary leak syndrome (i-CLS; imeko encomekayo apho iindawo zegazi zivuza kwimithambo yegazi kwaye zinokubangela ukufa). Tshela ugqirha wakho ngoko nangoko ukuba ufumana ubunzima bomzimba ngesiquphe; ukudumba kobuso, iingalo, imilenze, iinyawo, okanye nayiphi na enye indawo emzimbeni; ukuqhawukelwa ngumphefumlo; okanye isiyezi. Ugqirha wakho unokuphazamisa okanye ayeke unyango lwakho nge-tagraxofusp-erzs, kwaye angakuphatha ngamanye amayeza. Qiniseka ukuba uzilinganisela suku ngalunye ukuze ubone ukuba uyafumana ubunzima.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile ngaphambi nangexesha lonyango lwakho ukuze uqiniseke ukuba kukhuselekile ukuba ufumane i-tagraxofusp-erzs kwaye ujonge impendulo yomzimba wakho kunyango.

Inaliti yeTagraxofusp-erzs isetyenziselwa ukunyanga i-blasm plasmacytoid dendritic cell neoplasm (BPDCN; umhlaza wegazi obangela izilonda kulusu, kwaye unokusasazeka kumongo wethambo kunye nenkqubo ye-lymphatic) kubantu abadala nakubantwana abaneminyaka emi-2 ubudala nangaphezulu. I-Tagraxofusp-erzs ikudidi lwamayeza abizwa ngokuba yi-CD123 cytotoxin. Isebenza ngokubulala iiseli zomhlaza.

Inaliti yeTagraxofusp-erzs iza njengesisombululo (ulwelo) ukuba luxutywe kwaye kufakwe inaliti ngaphakathi (emthanjeni) ngaphezulu kwemizuzu eli-15. Ihlala inikwa kube kanye ngemini ngeentsuku 1, 2, 3, 4 kunye no-5 kumjikelo wonyango lweentsuku ezingama-21. Kumjikelo wokuqala wonyango kuyakufuneka uhlale esibhedlele kude kube ziiyure ezingama-24 emva kwedosi yakho yokugqibela (yesi-5) ukuze oogqirha nabongikazi bakwazi ukujonga ngononophelo kuyo nayiphi na imiphumela emibi. Kule mijikelo yonyango ilandelayo kuya kufuneka uhlale esibhedlele kangangeeyure ezi-4 emva kwethamo ngalinye.

Ugqirha wakho uya kukuphatha ngamanye amayeza malunga neyure enye ngaphambi kwethamo ngalinye ukukunceda ukukhusela iziphumo ezithile ebezingalindelekanga. Qiniseka ukuba uxelela ugqirha indlela oziva ngayo ngexesha lonyango lwakho kunye ne-tagraxofusp-erzs. Ugqirha wakho unokufuna ukulibazisa okanye ayeke unyango lwakho ukuba uneziphumo ebezingalindelekanga ezithile.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana i-tagraxofusp-erzs,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-tagraxofusp-erzs, nawaphi na amanye amayeza, okanye nasiphi na isithako se-tagraxofusp-erzs injection Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo kunye neemveliso zamayeza ozithathayo okanye oceba ukuzithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhulelwe, okanye ucwangcise ukukhulelwa. Kufuneka uthathe uvavanyo lokukhulelwa zingaphelanga iintsuku ezisi-7 phambi kokuqala unyango. Akufanele ukhulelwe ngexesha lonyango lwakho kunye ne-tagraxofusp-erzs. Sebenzisa ulawulo lokuzalwa olusebenzayo ngexesha lonyango kunye neentsuku ezisi-7 emva kwedosi yakho yokugqibela. Ukuba ukhulelwa ngelixa ufumana i-tagraxofusp-erzs, tsalela ugqirha wakho.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncancise ngexesha lonyango lwakho kunye ne-tagraxofusp-erzs kunye neentsuku ezisi-7 emva kwedosi yakho yokugqibela.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

I-Tagraxofusp-erzs inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• ukuqhina
• urhudo
• ukudinwa kakhulu
• intloko ebuhlungu
• ukunciphisa ukutya
• umqala obuhkungu
• iintlungu emqolo, iingalo, okanye imilenze
• ukukhohlela
• ubunzima bokulala okanye ukulala
• ndiziva ndiphakuzela okanye ndibhidekile
• kwaphuma impumlo
• amabala amancinci abomvu, ansundu, okanye mfusa kulusu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILumkiso ESIBALULEKILEYO tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• irhashalala, ukurhawuzelela, ukuphefumla nzima, izilonda zomlomo okanye ukudumba
• ukudinwa okugqithisileyo, ubumthubi besikhumba okanye amehlo, ukulahleka kwesidlo, iintlungu kwinxalenye ephezulu yesisu
• umkhuhlane, ukubanda
• ukubetha kwentliziyo ngokukhawuleza
• igazi kumchamo

I-Tagraxofusp-erzs inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Elzonris^®