Umbhali: Marcus Baldwin
Umhla Wokudalwa: 17 Isilimela 2021
Hlaziya Umhla: 17 Eyenkanga 2024
Anonim
Pretomanid: A FDA approved new treatment for highly treatment-resistant tuberculosis (TB) of lungs
Ividiyo: Pretomanid: A FDA approved new treatment for highly treatment-resistant tuberculosis (TB) of lungs

Umxholo

I-Pretomanid isetyenziswa kunye ne-bedaquiline (Sirturo) kunye ne-linezolid (Zyvox) ukunyanga isifo sephepha esinganyangekiyo ngamachiza amaninzi (MDR-TB; usulelo olubi oluchaphazela imiphunga engenakunyangwa ngamanye amayeza) kubantu abadala. I-Pretomanid ikudidi lwamayeza abizwa ngokuba zii-antimycobacterials. Isebenza ngokubulala iintsholongwane ezibangela isifo sephepha.

I-Pretomanid iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye yonke imihla ngokutya kangangeeveki ezingama-26 okanye ngaphezulu. Thatha i-pretomanid malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-pretomanid ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngamanzi.

Qhubeka nokuthatha i-pretomanid de ugqibe amayeza kwaye ungaphoswa ngamayeza, nokuba uziva ungcono. Ukuba uyeka ukuthatha i-pretomanid ngokukhawuleza okanye weqe amathamo, usulelo lwakho alunakuphathwa ngokupheleleyo kwaye ibhaktheriya inokumelana namayeza okubulala iintsholongwane. Oku kuyakwenza ukuba usulelo lwakho lube nzima ukunyanga kwixa elizayo. Uyakuthatha inxaxheba kwinkqubo yonyango ethe ngqo ukuze uqiniseke ukuba uwathatha onke amayeza akho njengoko kuyalelwe. Kule nkqubo, umsebenzi wokhathalelo lwempilo uya kukunika idosi nganye yamayeza kwaye uya kujonga njengoko uginya amayeza.


Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-pretomanid,

  • xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uyaliwa yi-pretomanid, bedaquiline, linezolid, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi zeepretomanid. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
  • xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: efavirenz (Sustiva, eAtripla), methotrexate (Rheumatrex, Trexall), okanye rifampin (Rifadin, Rimactane, eRifamate, eRifater). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-pretomanid, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
  • xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort. Musa ukuthatha i-wort yaseSt. John okanye ezinye iimveliso zemifuno ngelixa uthatha i-pretomanid.
  • xelela ugqirha wakho ukuba wena okanye ilungu losapho une-QT syndrome ende (imeko eyonyusa umngcipheko wokuba nesifo sentliziyo esingaqhelekanga esinokubangela ukuba utyhafe okanye usweleke ngesiquphe), okanye olunye uhlobo lokubetha kwentliziyo okungaqhelekanga okanye ingxaki yesingqisho sentliziyo. Kwakhona xelela ugqirha wakho ukuba unayo okanye wakha wanamaqondo asezantsi egazi e-calcium, i-magnesium okanye i-potassium egazini lakho, isifo sentliziyo, ukusilela kwentliziyo (HF; imeko apho intliziyo ingakwazi ukumpompa igazi elaneleyo kwamanye amalungu omzimba) , ukuxhuzula, usulelo lwe-HIV, okanye idlala lengqula, isibindi okanye isifo sezintso.
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-pretomanid, biza ugqirha wakho.
  • Kuya kufuneka uyazi ukunqanda ukusela iziselo ezinxilisayo. Ukusela utywala kwandisa umngcipheko wokuba uya kuba neziphumo ebezingalindelekanga ezimandundu ezivela kwi-pretomanid.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.


Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Pretomanid inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • induna
  • intloko ebuhlungu
  • isilungulela
  • Ukuphelelwa ngumdla wokutya
  • ukuhla ukusinda
  • irhashalala
  • ukurhawuzelela
  • isisu esibuhlungu
  • isicaphucaphu
  • ukugabha
  • urhudo
  • ukuqhina
  • isikhumba esomileyo
  • ubunzima bokulala okanye ukulala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

  • ukuphelelwa ngumdla, isicaphucaphu, amehlo atyheli okanye ulusu, iintlungu kwindawo ephezulu yesisu, okanye umchamo omnyama
  • iintlungu, ukuba ndindisholo, okanye ubuthathaka ezandleni, ezinyaweni, okanye kwamanye amalungu omzimba; okanye iingxaki ngokulinganisela
  • utshintsho lombono
  • ukukhawuleza kwentliziyo okanye okungaqhelekanga; uziva unesiyezi; okanye isiqaqa
  • ulusu olukhanyayo okanye ukudinwa kakhulu
  • isicaphucaphu ngokuphindaphindiweyo nokugabha; ukuphefumla ngokukhawuleza; ukudideka; okanye ndiziva ndidiniwe
  • ngequbuliso, iintlungu zokuhlaba esifubeni, ngakumbi xa uphefumla ngaphakathi nangaphandle

I-Pretomanid inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.


Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ngaphambi nangexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwi-pretomanid. Kuya kufuneka ubene-electrocardiogram (ECG; uvavanyo olulinganisa umsebenzi wombane wentliziyo) ngaphambi konyango lwakho kunye namaxesha aliqela ngexesha lonyango lwakho ukuze ubone ukuba eli yeza liyichaphazela njani isingqisho sentliziyo yakho.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

Ukuhlaziywa kokugqibela-11/15/2019

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