IDoravirine, iLamivudine, kunye neTenofovir

Umxholo

• Ngaphambi kokuba uthathe i-doravirine, lamivudine, kunye ne-tenofovir,
• IDoravirine, lamivudine, kunye ne-tenofovir zinokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

Indibaniselwano yedoravirine, lamivudine, kunye ne-tenofovir akufuneki isetyenziselwe ukunyanga usulelo lwentsholongwane ye-hepatitis B (HBV; usulelo lwesibindi oluqhubekayo). Xelela ugqirha wakho ukuba unayo okanye ucinga ukuba unayo i-HBV. Ugqirha wakho angakuvavanya ukuze ubone ukuba unayo i-HBV ngaphambi kokuba uqale unyango lwakho nge-doravirine, lamivudine, kunye ne-tenofovir. Ukuba unayo i-HBV kwaye uthatha i-doravirine, lamivudine, kunye ne-tenofovir, imeko yakho inokuba mandundu mandundu xa uyeka ukuthatha i-doravirine, lamivudine, kunye ne-tenofovir.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kukuvavanya kwaye a-odole iimvavanyo zelebhu ngaphambi, ngexesha, kunye rhoqo kwiinyanga ezininzi emva kokuba uyekile ukuthatha i-doravirine, lamivudine, kunye ne-tenofovir.

Thetha nogqirha wakho malunga nomngcipheko (s) wokuthatha i-doravirine, lamivudine, kunye ne-tenofovir.

Indibaniselwano yedoravirine, lamivudine, kunye ne-tenofovir isetyenziselwa ukunyanga usulelo lwe-immunodeficiency virus (HIV) kubantu abadala abangakhange banyangwe ngamanye amayeza e-HIV. Indibaniselwano ikwasetyenziselwa ukutshintsha unyango lwangoku lwamayeza kubantu abathile abasele bethatha amayeza e-HIV. UDoravirine ukwiklasi yamayeza abizwa ngokuba yi-non-nucleoside reverse transcriptase inhibitors (NNRTIs). I-Lamivudine kunye ne-tenofovir bakudidi lwamayeza abizwa ngokuba yi-nucleoside reverse transcriptase inhibitors (NRTIs). Indibaniselwano yedoravirine, lamivudine, kunye ne-tenofovir isebenza ngokwehlisa inani le-HIV emzimbeni. Nangona indibaniselwano yedoravirine, lamivudine, kunye ne-tenofovir ingayinyangi i-HIV, inokuwanciphisa amathuba okuba ne-immunodeficiency syndrome (i-AIDS) kunye nezifo ezinxulumene ne-HIV ezinje ngezifo ezomeleleyo okanye umhlaza. Ukuthatha la mayeza kunye nokwabelana ngesondo okukhuselekileyo nokwenza olunye utshintsho kwindlela yokuphila kunokunciphisa umngcipheko wokuhambisa (ukusasaza) intsholongwane kagawulayo kwabanye abantu.

Indibaniselwano yedoravirine, lamivudine, kunye ne-tenofovir iza njengetafile emayithathwe ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kube kanye yonke imihla. Thatha idoravirine, lamivudine, kunye ne-tenofovir malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha idoravirine, lamivudine, kunye ne-tenofovir ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Indibaniselwano yedoravirine, lamivudine, kunye ne-tenofovir iyanceda ukulawula usulelo lwe-HIV kodwa ayiyinyangi. Qhubeka nokuthatha i-doravirine, lamivudine, kunye ne-tenofovir nokuba uziva uphilile. Sukuyeka ukuthatha i-doravirine, lamivudine, kunye ne-tenofovir ngaphandle kokuthetha nogqirha wakho. Ukuba uyeka ukuthatha i-doravirine, lamivudine, kunye ne-tenofovir okanye uphose idosi, imeko yakho kunokuba nzima ukunyanga. Xa unikezelo lwedoravirine, lamivudine, kunye ne-tenofovir liqala ukusebenza phantsi, fumana okungakumbi kugqirha wakho okanye usokhemesti.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-doravirine, lamivudine, kunye ne-tenofovir,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana nedoravirine, lamivudine, kunye ne-tenofovir, nawaphi na amanye amayeza, okanye nasiphi na isithako esenziwe kwi-doravirine, lamivudine, kunye neepilisi ze-tenofovir. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha i-carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), enzalutamide (Xtandi), mitotane (Lysodren), oxcarbazepine (Trileptal), phenobarbital, phenytoin (Dilantin, Phenytek), rifampin (Rifampin) eRifamate, eRifater), rifapentine (Priftin), okanye eSt John's wort. Ugqirha wakho uyakukuxelela ukuba ungathathi i-doravirine, lamivudine, kunye ne-tenofovir ukuba ngoku uthatha elinye okanye ngaphezulu kula mayeza okanye uthathe elinye lawo kwiiveki ezi-4 ezidlulileyo.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: acyclovir (Sitavig, Zovirax); ii-aminoglycosides ezinje nge-amikacin, gentamicin, streptomycin, kunye ne-tobramycin; i-aspirin kunye nezinye iyeza ezichasayo (i-NSAIDs) ezinje nge-ibuprofen (Advil, Motrin) kunye ne-naproxen (Aleve, Naprosyn); cidofovir; ganciclovir (icytovene); I-ledipasvir / sofosbuvir (iHarvoni); isofosbuvir / velpatasvir (Epculsa); i-sorbitol okanye amayeza aqukethe i-sorbitol; i-valacyclovir (iValtrex); kunye ne-valganciclovir (Valcyte). Xelela ugqirha wakho ukuba uthatha i-rifabutin (Mycobutin) okanye uyithathile kwiiveki ezi-4 ezidlulileyo. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-doravirine, lamivudine, kunye ne-tenofovir, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba unayo nayiphi na imiqathango ekhankanywe kwicandelo LESILUMKISO ELIBALULEKILEYO, okanye ukuba ukhe wanengxaki yamathambo kubandakanya ne-osteoporosis (imeko apho amathambo esiba buthathaka kwaye abuthathaka kwaye aphule ngokulula), ukwaphuka kwamathambo, okanye izintso isifo.
• xelela ugqirha wakho ukuba unaso okanye ukhe wasifumana isifo esingahambiyo okanye esiza kwaye sifike njenge cytomegalovirus (CMV; usulelo lwentsholongwane olunokubangela iimpawu kwizigulana ezinamajoni omzimba abuthathaka), isifo se-mycobacterium avium tata (MAC; usulelo lwebhaktiriya olunokubangela iimpawu ezinzulu kubantu abane-AIDS), inyumoniya, okanye isifo sephepha (i-TB; uhlobo losulelo lwemiphunga); okanye isifo esizenzekelayo (iimeko ezithi zikhule xa amajoni omzimba ehlasela iiseli ezisempilweni emzimbeni ngempazamo) ezinjengesifo seMangcwaba (imeko apho umzimba uhlasela idlala lengqula ubangela ukuba usebenze kakhulu), i-polymyositis (imeko ebangela ubuthathaka bemisipha kodwa hayi ukuqubuka kolusu), isifo sikaGuillain-Barré (ubuthathaka, ukurhawuzelela, kunye nokukhubazeka okunokubakho ngenxa yomonakalo wemithambo-luvo ngesiquphe), kunye ne-autoimmune hepatitis (imeko apho iiseli zamajoni omzimba zihlasela isibindi).
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ukuba ukhulelwa ngelixa uthatha i-doravirine, lamivudine, kunye ne-tenofovir, tsalela ugqirha wakho. Tshela ugqirha wakho ukuba uncelisa. Akufuneki uncancise xa wosulelwe yi-HIV okanye ukuba uthatha idoravirine, lamivudine, kunye ne-tenofovir.
• Kuya kufuneka uyazi ukuba ngelixa uthatha amayeza ukunyanga usulelo lwe-HIV, amajoni akho omzimba angomelela kwaye aqale ukulwa nezinye izifo ezazisele zisemzimbeni wakho okanye zibangele ezinye iimeko zenzeke. Oku kunokubangela ukuba ukhule iimpawu zolo sulelo okanye iimeko. Ukuba uneempawu ezintsha okanye eziba mandundu ngexesha lonyango lwakho nge-doravirine, lamivudine, kunye ne-tenofovir qiniseka ukuxelela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

IDoravirine, lamivudine, kunye ne-tenofovir zinokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isiyezi
• isicaphucaphu
• amaphupha angaqhelekanga
• ubunzima bokulala okanye ukulala
• ukozela
• urhudo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ukuncipha kokuchama okanye ukudumba kwemilenze
• iintlungu zethambo; iintlungu ezingalweni okanye emilenzeni; iintlungu zemisipha okanye ubuthathaka; okanye ukwaphuka kwamathambo

IDoravirine, lamivudine, kunye ne-tenofovir zinokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Musa ukuyisusa i-desiccant (iarhente yokomisa) kwibhotile.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina unikezelo lwedoravirine, lamivudine, kunye ne-tenofovir ngesandla. Sukulinda de uphelelwe ngamayeza ukuze uphinde uzalise amayeza akho.

Musa ukuvumela nabani na ukuba athathe amayeza akho.Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Delstrigo^®