Ubushushu beDiroximel

Umxholo

• Ngaphambi kokuba uthathe i-diroximel fumarate,
• I-Diroximel fumarate inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

I-Diroximel fumarate isetyenziselwa ukunyanga abantu abadala ngeendlela ezahlukeneyo ze-multiple sclerosis (MS; isifo apho iimbilini zingasebenzi kakuhle kwaye abantu banokufumana ubuthathaka, ukuphazamiseka, ukulahleka kokulungelelaniswa kwemisipha, kunye neengxaki ngombono, intetho kunye nokulawula isinyi) kubandakanya:

• I-CIS; Iimpawu zempawu zemithambo-luvo ezihlala ubuncinci iiyure ezingama-24),
• Iifom zokuphinda zibuyele kwakhona (ikhosi yesifo apho iimpawu ziyavela khona amaxesha ngamaxesha), okanye
• iifomati zesekondari eziqhubekayo (ikhosi yesifo apho ukubuyela umva kwenzeka rhoqo).

I-Diroximel fumarate ikwiklasi yamayeza abizwa ngokuba yi-Nrf2 activators. Isebenza ngokunciphisa ukudumba kunye nokuthintela ukonakala kwemithambo-luvo kunokubangela iimpawu ze-multiple sclerosis.

I-Diroximel fumarate iza njengokulibaziseka-ukukhutshwa (kukhupha iyeza emathunjini ukunqanda ukonakala kwamayeza sisisu acid) capsule ukuba uyithathe ngomlomo. Ihlala ithathwa kabini yonke imihla. Thatha i-diroximel fumarate kumaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-diroximel fumarate ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

I-Diroximel fumarate inokuthathwa kunye okanye ngaphandle kokutya. Nangona kunjalo, sukuyithatha ngesidlo esinamafutha aphezulu, esinekhalori eninzi okanye isinekhi; isidlo okanye i-snack kufuneka ibe neekhalori ezingaphantsi kwe-700 kwaye ibe ngaphantsi kwe-30 gram yamafutha.

Musa ukusela iziselo ezinxilisayo ngaxeshanye uthatha i-diroximel fumarate.

Ginya zonke iicapsule zokukhululwa kulibazisekile; musa ukwahlulahlula, ukuhlafuna, ukutyumza, okanye ukufefa.

Ungathatha i-aspirin egalelwe i-non-enteric (325 mg okanye ngaphantsi) imizuzu engama-30 ngaphambi kokuba uthathe i-diroximel fumarate ukunciphisa ithuba lokugungxula (ubuso bomvu obomvu) ngexesha lonyango lwakho.

Ugqirha wakho uya kukuqala ngedosi esezantsi ye-diroximel fumarate kwaye wandise idosi yakho emva kweentsuku ezisi-7.

I-Diroximel fumarate inokunceda ukulawula i-multiple sclerosis, kodwa ayizukuyinyanga. Qhubeka uthathe i-diroximel fumarate nokuba uziva uphilile. Ungayeki ukuthatha i-diroximel fumarate ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-diroximel fumarate,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-diroximel fumarate, i-dimethyl fumarate (Tecfidera), nawaphi na amanye amayeza, okanye naziphi na izithako ezikwipilisi ze-diroximel fumarate ezilibaziseko zokukhululwa. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha i-dimethyl fumarate (Tecfidera). Ugqirha wakho uya kukuxelela ukuba ungathathi i-diroximel fumarate ukuba uthatha eli yeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba unosulelo, kubandakanya usulelo oluza luphela kunye nosulelo olungapheliyo olungapheliyo, okanye ukuba unesibalo segazi esimhlophe esiphantsi okanye isifo sesibindi okanye sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-diroximel fumarate, tsalela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Diroximel fumarate inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukufudumala, ukuba bomvu, ukurhawuzelela, okanye ukutshisa kolusu
• isisu esibuhlungu
• urhudo
• isicaphucaphu
• ukugabha
• isilungulela

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ubunzima bokuphefumla okanye ukugwinya
• urhwebo
• irhashalala
• ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ubuthathaka kwelinye icala lomzimba, ukungazinzi ezingalweni okanye emilenzeni, iingxaki zombono, utshintsho kwindlela ocinga ngayo nakwimemori, ukudideka, okanye utshintsho kubuntu
• ukudinwa, ukulahleka kwesidlo, iintlungu kwicala lasekunene lesisu sakho, umchamo omnyama, okanye utyheli kolusu okanye lamehlo

I-Diroximel fumarate inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Ugqirha wakho unokuyalela uvavanyo lwegazi ngaphambi kokuba uqale unyango lwakho kwaye unokuyalela iimvavanyo ezithile zebhu ngexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwi-diroximel fumarate.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Amanani^®