Voxelotor

Umxholo

• Ngaphambi kokuthatha i-voxelotor,
• IVoxelotor inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, yeka ukuthatha i-voxelotor kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

IVoxelotor isetyenziselwa ukunyanga isifo selebheli (isifo esizelwe njengelifa) kubantu abadala nakubantwana abaneminyaka eli-12 ubudala nangaphezulu. IVoxelotor ikwiklasi yamayeza abizwa ngokuba yihemoglobin S (HbS) polymerization inhibitors. Isebenza ngokunceda i-hemoglobin (iprotein ekwiiseli ezibomvu zegazi) ukubambelela kwioksijini engaphezulu kunye nokumisa iiseli ezibomvu zegazi ekubeni zingalungiseki kakuhle.

IVoxelotor iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye yonke imihla kunye okanye ngaphandle kokutya. Thatha i-voxelotor malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-voxelotor ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuthatha i-voxelotor,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-voxelotor, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze-voxelotor. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zilandelayo: carbamazepine (Tegretol); i-clarithromycin (i-Biaxin, kwi-Prevpac); idiltiazem (Cardizem, Cartia, Diltzac, Taztia); erythromycin (E-Mycin, Erythrocin); amayeza okunyanga i-HIV kubandakanya i-didanosine (Videx), efavirenz (Sustiva, e-Atripla), nelfinavir (Viracept), ritonavir (Norvir, e-Kaletra), okanye i-saquinavir (Fortovase, Invirase); nefazodone; phenobarbital; phenytoin (Dilantin); irifabutin (Mycobutin); irifampin (Rifadin, Rimactane, eRifamate, eRifater); okanye ii-steroids zomlomo ezinje nge-dexamethasone, methylprednisolone (Medrol), kunye ne-prednisone (iRayos). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ukhe unesifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ukuba ukhulelwa ngelixa uthatha i-voxelotor, tsalela umnxeba ugqirha wakho.
• xelela ugqirha wakho ukuba uncelisa. Musa ukuncancisa ngelixa uthatha i-voxelotor kunye neeveki ezi-2 emva kwedosi yakho yokugqibela.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-voxelotor.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yamagilebhisi ngelixa uthatha eli yeza.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethosi rhoqo ngosuku olulandelayo.

IVoxelotor inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• urhudo
• isisu esibuhlungu
• isicaphucaphu
• ifiva

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, yeka ukuthatha i-voxelotor kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

• ukukhawuleza, imihlathi, ukuphefumula okufutshane, okanye ukudumba kobuso

IVoxelotor inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha i-voxelotor.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• I-Oxbryta^®