Umbhali: Virginia Floyd
Umhla Wokudalwa: 12 Eyethupha 2021
Hlaziya Umhla: 15 Eyenkanga 2024
Anonim
The Role of CGRP as Targeted Treatment for Migraine -  Module 2: Ubrogepant
Ividiyo: The Role of CGRP as Targeted Treatment for Migraine - Module 2: Ubrogepant

Umxholo

I-Ubrogepant isetyenziselwa ukunyanga iimpawu zentloko ebuhlungu (ebukhali, iintloko ezibethayo ngamanye amaxesha ezihamba nesicaphucaphu kunye nobuntununtunu kwisandi okanye ukukhanya). I-Ubrogepant ikudidi lwamayeza abizwa ngokuba yi-calcitonin enxulumene ne-peptide receptor antagonists. Isebenza ngokuthintela isenzo sento ethile yendalo emzimbeni ebangela iintlungu zentloko. I-Ubrogepant ayikuthinteli ukuhlaselwa kwe-migraine okanye ukunciphisa inani leentloko onazo.

I-Ubrogepant iza njengecwecwe lokuthatha ngomlomo. Ngokuqhelekileyo kuthathwa kwisibonakaliso sokuqala se-migraine. Ukuba iimpawu zakho ziyaphucuka emva kokuba uthathe i-ubrogepant kodwa ubuya emva kweeyure ezi-2 okanye ngaphezulu, ugqirha wakho angakuxelela ukuba ungathatha ipilisi yesibini. Thetha nogqirha wakho ukuze ubone ukuba ungathatha idosi yesibini xa kufuneka. Ugqirha wakho uya kukuxelela elona nani liphezulu leetafile onokuthi uzithathe kwisithuba seeyure ezingama-24. Ugqirha wakho uya kukuxelela elona nani liphezulu le-migraine yentloko ekufuneka uyinyange ngeepilisi ze-ubrogepant kwisithuba seentsuku ezingama-30. Landela umkhombandlela kwiphakheji okanye kwilebhile kagqirha ngocoselelo, kwaye ubuze ugqirha okanye usokhemesti ukuba akuchaze nangayiphi na indawo ongayiqondiyo. Thatha ubrogepant ngokuchanekileyo njengoko kuyalelwe. Sukuyithatha ngaphezulu okanye ngaphantsi okanye uyithathe rhoqo kunokuyalelwa yelebhile yephakheji okanye umiselwe ngugqirha wakho.


Fowunela ugqirha wakho ukuba iintloko zakho aziphili okanye zenzeke rhoqo emva kokuthatha i-ubrogepant.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe ubrogepant,

  • xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa kwi-ubrogepant, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze-ubrogepant. Buza usokhemesti wakho uluhlu lwezithako.
  • xelela ugqirha wakho ukuba loluphi olunye amayeza owathathayo, ngakumbi i-clarithromycin, itraconazole (Onmel, Sporanox, Tolsura), okanye ketoconazole. Ugqirha wakho uya kukuxelela ukuba ungathathi i-ubrogepant ukuba uthatha elinye okanye nangaphezulu la mayeza.
  • xelela ugqirha wakho ukuba loluphi olunye amayeza owathathayo, ngakumbi i-ciprofloxacin (Cipro), cyclosporine (Gengraf, Neoral, Sandimmune), fluconazole (Diflucan), fluvoxamine (Luvox), okanye verapamil (Calan, Verelan, in Tarka). Ugqirha wakho unokukuxelela ukuba ungathathi icwecwe lesibini le-ubrogepant kwisithuba seeyure ezingama-24 ukuba uthatha elinye okanye ngaphezulu kula mayeza.
  • xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nononyango, iivithamini, izongezo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: icarvedilol (Coreg), eltrombopag (Promacta), phenobarbital, phenytoin (Dilantin, Phenytek), quinidine (eNuedexta), kunye nerifampin (Rifadin, Rimactane, eRifamate, Rifater). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-ubrogepant, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
  • xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi i-curcumin kunye neSt.
  • xelela ugqirha wakho ukuba ukhe wanengxaki yezintso okanye isibindi.
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-ubrogepant, tsalela umnxeba ugqirha wakho.

Sukuyithatha ithebhulethi yesibini ye-ubrogepant ngaphakathi kweeyure ezingama-24 zokuthatha idosi yokuqala ukuba usela ijusi yegrapefruit okanye utya iidiliya. Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yamagilebhisi ngelixa uthatha eli yeza.


I-Ubrogepant inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • isicaphucaphu
  • ukozela
  • umlomo owomileyo

I-Ubrogepant inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.


Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho.

Kuya kufuneka ugcine idayari yentloko ngokubhala phantsi xa unentloko kwaye xa uthatha i-ubrogepant.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • Ubrelvy®
Ukuhlaziywa kokugqibela-03/15/2020

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