Umbhali: Joan Hall
Umhla Wokudalwa: 5 Eyomdumba 2021
Hlaziya Umhla: 23 Eyenkanga 2024
Anonim
BLENREP (belantamab mafodotin-blmf) Mechanism of Action in Multiple Myeloma
Ividiyo: BLENREP (belantamab mafodotin-blmf) Mechanism of Action in Multiple Myeloma

Umxholo

Inaliti ye-Belantamab mafodotin-blmf inokubangela iingxaki ezinkulu zamehlo okanye umbono, kubandakanya ukulahleka kombono. Tshela ugqirha wakho ukuba unayo okanye unembali yokubona okanye iingxaki zamehlo. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: umbono ophazamisayo, utshintsho lombono okanye ilahleko, okanye amehlo owomileyo.

Ngenxa yomngcipheko weengxaki zombono ngeli yeza, i-belantamab mafodotin-blmf ifumaneka kuphela kwinkqubo ekhethekileyo ebizwa ngokuba yi-Blenrep REMS®. Wena, ugqirha wakho, kunye nendawo yakho yokhathalelo lwempilo kufuneka ubhalise kule nkqubo ngaphambi kokuba ufumane i-belantamab mafodotin-blmf. Buza ugqirha wakho ngolwazi olungakumbi malunga nale nkqubo.

Musa ukunxiba iilensi zonxibelelwano ngexesha lonyango ngaphandle kokuba uyalelwe ngugqirha okanye ngugqirha wamehlo. Sebenzisa i-eye-lubricant-free eye-eye-drop eye njengoko kuyalelwe ngugqirha wakho ngexesha lonyango lwakho.

Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi ukuba eli yeza likuchaphazela njani umbono wakho.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya ku-odola uvavanyo oluthile ngaphambi nangexesha lonyango lwakho. Ugqirha wakho uya kuku-odola kuvavanyo lwamehlo ngaphambili nangamaxesha amaninzi kunyango lwakho, ngakumbi ukuba ubona utshintsho kumbono.


Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-belantamab mafodotin-blmf kwaye ngalo lonke ixesha uzalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Thetha nogqirha wakho malunga nemingcipheko yokufumana i-belantamab mafodotin-blmf.

Inaliti ye-Belantamab mafodotin-blmf isetyenziselwa ukunyanga i-myeloma (uhlobo lomhlaza womongo wethambo) obuyileyo okanye ongaphucukanga kubantu abadala abafumene ubuncinci amanye amayeza ama-4. I-Belantamab mafodotin-blmf ikwiklasi yamayeza abizwa ngokuba ngama-anti-drug conjugates. Isebenza ngokubulala iiseli zomhlaza.

I-Belantamab mafodotin-blmf iza njengomgubo wokudityaniswa nolwelo kwaye itofwe ngaphakathi (emthanjeni) ngaphezulu kwemizuzu engama-30 ngugqirha okanye ngumongikazi esibhedlele okanye kwiziko lonyango. Ihlala inikwa kube kanye kwiiveki ezi-3. Umjikelo unokuphindwa njengoko ucetyiswa ngugqirha wakho. Ubude bonyango lwakho buxhomekeke kwindlela ophendula ngayo emzimbeni wakho kunyango kunye naziphi na iziphumo ebezingalindelekanga ohlangabezana nazo.


Ugqirha okanye umongikazi uya kukujonga ngokusondeleyo ngelixa ufumana amayeza ukuze uqiniseke ukuba awunampendulo imbi kunyango. Xelela ugqirha okanye umongikazi ngoko nangoko ukuba unazo naziphi na kwezi mpawu zilandelayo: Ukugodola; ukugungxula; ukurhawuzelela okanye irhashalala; ukuphefumla kancinci, ukukhohlela, okanye ukuvutha; ukudinwa; ifiva; utywala okanye intloko; okanye ukudumba kwemilebe yakho, ulwimi, umqala, okanye ubuso.

Ugqirha wakho unokunciphisa idosi okanye ayeke unyango lwakho okwethutyana okanye ngokusisigxina. Oku kuxhomekeke ekusebenzeni kakuhle kweyeza kunye neziphumo ebezingalindelekanga ohlangabezana nazo. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho nge-belantamab mafodotin-blmf.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti yebelantamab mafodotin-blmf,

  • xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-belantamab mafodotin-blmf, nawaphi na amanye amayeza, okanye naziphi na izithako kwi-belantamab mafodotin-blmf injection. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
  • xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
  • xelela ugqirha wakho ukuba ukhe wanengxaki yokopha.
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ucwangcise ukuba ngutata womntwana. Akufanele uqale ukufumana inaliti ye-belantamab mafodotin-blmf de uvavanyo lokukhulelwa lubonise ukuba awukhulelwe. Ukuba ungumfazi okwaziyo ukukhulelwa, kuya kufuneka usebenzise ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho kunye neenyanga ezi-4 emva kwedosi yakho yokugqibela. Ukuba uyindoda kunye neqabane lomfazi onokukhulelwa, kuya kufuneka usebenzise ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho kunye neenyanga ezi-6 emva kwedosi yakho yokugqibela. Thetha nogqirha wakho malunga neendlela zolawulo lokuzalwa eziza kukusebenzela. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa ufumana i-belantamab mafodotin-blmf injection, biza ugqirha wakho. Inaliti ye-Belantamab mafodotin-blmf inokwenzakalisa umntwana ongekazalwa.
  • xelela ugqirha wakho ukuba uncelisa. Musa ukuncancisa ngexesha lonyango lwakho kunye neenyanga ezi-3 emva kwedosi yakho yokugqibela.
  • Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuchuma emadodeni nakwabasetyhini. Thetha nogqirha wakho malunga nemingcipheko yokufumana inaliti ye-belantamab mafodotin-blmf.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.


Ukuba uphoswa idinga lokufumana idosi ye-belantamab mafodotin-blmf, tsalela ugqirha wakho kwangoko.

I-Belantamab mafodotin-blmf inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • isicaphucaphu
  • ukuqhina
  • urhudo
  • Ukuphelelwa ngumdla wokutya
  • intlungu edibeneyo okanye yomqolo
  • ukudinwa

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

  • ukopha okungaqhelekanga okanye ukugruzuka

I-Belantamab mafodotin-blmf inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nebelantamab mafodotin-blmf.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • UBlenrep®
Ukuhlaziywa kokugqibela-09/15/2020

Umdla

Ukutya okungcono kwe-10 ukufumana ubunzima bemisipha

Ukutya okungcono kwe-10 ukufumana ubunzima bemisipha

Ukutya ukufumana ubunzima bemi ipha kutyebile kwiiproteni ezinjenge nyama, amaqanda kunye nemidumba efana neembotyi namandongomane, umzekelo. Kodwa ukongeza kwiiproteni, umzimba ufuna amandla amaninzi...
Umhlaza onzima: yintoni, iimpawu kunye nonyango

Umhlaza onzima: yintoni, iimpawu kunye nonyango

Umhlaza onzima i ilonda e incinci e inokubonakala kumalungu okuzala okanye ezimpundu okuboni a ukuba u ulelo lubangelwa yint holongwane I-Treponema pallidum, eyi-microorgani m ejongene negcu huwa.Ukub...