ICasirivimab kunye neImdevimab Inaliti

Umxholo

• Ngaphambi kokufumana i-casirivimab kunye ne-imdevimab,
• ICasirivimab kunye ne-imdevimab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zikwicandelo le-INDLELA, biza ugqirha ngokukhawuleza okanye ufumane unyango olukhawulezileyo.

Indibaniselwano yecasirivimab kunye ne-imdevimab kungoku nje ifundelwa unyango lwe-coronavirus isifo se-2019 (i-COVID-19) ebangelwa yintsholongwane ye-SARS-CoV-2.

Ulwazi olulinganiselweyo lwezonyango olufumanekayo ngeli xesha ukuxhasa ukusetyenziswa kwe-casirivimab kunye ne-imdevimab kunyango lwe-COVID-19. Ulwazi oluthe kratya luyafuneka ukwazi ukuba isebenza kakuhle kangakanani i-casirivimab kunye ne-imdevimab kunyango lwe-COVID-19 kunye neziganeko ezimbi ezivela kuyo.

Indibaniselwano ye-casirivimab kunye ne-imdevimab khange ifumane uphononongo oluqhelekileyo ukuze luvunyiwe yi-FDA ukuze isetyenziswe. Nangona kunjalo, i-FDA ivume iSigunyaziso sokuSetyenziswa ngokuNgxamisekileyo (i-EUA) ukuvumela abantu abadala abangalaliswanga esibhedlele kunye nabantwana abaneminyaka eli-12 ubudala nangaphezulu abanobulali ukuya kuthi ga kwiimpawu ze-COVID-19 zokufumana inaliti ye-casirivimab kunye ne-imdevimab.

Thetha nogqirha wakho malunga nobungozi kunye nezibonelelo zokufumana eli yeza.

Indibaniselwano ye-casirivimab kunye ne-imdevimab isetyenziselwa ukunyanga usulelo lwe-COVID-19 kubantu abadala abangalaliswanga esibhedlele nakubantwana abaneminyaka eli-12 ubudala nangaphezulu abanobunzima obungama-88 eekhilogram (40 kg) nabaneempawu ezithi xhaxhe kwi-COVID-19. Umdibaniso usetyenziswa kubantu abaneemeko ezithile zonyango ezibenza babe semngciphekweni omkhulu wokukhula kweempawu ezinzima ze-COVID-19 okanye isidingo sokulaliswa esibhedlele kusulelo lwe-COVID-19. I-Casirivimab kunye ne-imdevimab bakudidi lwamayeza abizwa ngokuba zii-antibodies ze-monoclonal. Basebenza ngokuthintela isenzo sento ethile yendalo emzimbeni ukunqanda ukwanda kwentsholongwane.

Ukudityaniswa kwecasirivimab kunye ne-imdevimab kuza njengesisombululo (ulwelo) sokudityaniswa nolwelo kunye nokujova kancinci emthanjeni ngaphezulu kwemizuzu engama-60 ngugqirha okanye ngumongikazi. Inikwa njengedosi yexesha elinye ngokukhawuleza emva kovavanyo oluqinisekileyo lwe-COVID-19 kwaye kwiintsuku ezili-10 emva kokuqala kweempawu ze-COVID-19 zosulelo ezinje ngomkhuhlane, ukukhwehlela, okanye ukuphefumla kancinci.

Ukudityaniswa kwecasirivimab kunye ne-imdevimab kunokubangela ukusabela okunobuzaza ngexesha nasemva kokufakwa kweyeza. Ugqirha okanye umongikazi uya kukujonga ngononophelo ngelixa ufumana amayeza kunye neyure e-1 emva kokuba ufumene. Xelela ugqirha wakho okanye umongikazi kwangoko ukuba unazo naziphi na kwezi mpawu zilandelayo ngexesha okanye emva kokumiliselwa: umkhuhlane, ukugodola, isicaphucaphu, intloko ebuhlungu, utshintsho kwintliziyo yakho, iintlungu esifubeni, ubuthathaka okanye ukudinwa, ukudideka, ingxaki yokuphefumla okanye ukuphefumla kancinci, ukuvutha , ukuqaqanjelwa ngumqala, irhashalala, urhashalala, ukurhawuzelela, iintlungu zemisipha okanye iintlungu, ukubila, isiyezi ingakumbi xa umile, okanye ukudumba kobuso, umqala, ulwimi, imilebe okanye amehlo. Ugqirha wakho unokufuna ukunciphisa ukunyuswa kwakho okanye ayeke unyango lwakho ukuba uneziphumo ebezingalindelekanga.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana i-casirivimab kunye ne-imdevimab,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-casirivimab, imdevimab, nawaphi na amanye amayeza, okanye nasiphi na isithako esenziwe kwi-casirivimab kunye ne-imdevimab injection. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: amayeza e-immunosuppressive anjenge cyclosporine (Gengraf, Neoral, Sandimmune), prednisone, kunye ne tacrolimus (Astagraf, Envarsus, Prograf). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wakha naziphi na iimeko zonyango.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa ufumana i-casirivimab kunye ne-imdevimab, biza ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

ICasirivimab kunye ne-imdevimab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• iintlungu, ukopha, ukutyumka ulusu, ukukhathazeka, ukudumba, okanye usuleleko kwindawo yenaliti

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zikwicandelo le-INDLELA, biza ugqirha ngokukhawuleza okanye ufumane unyango olukhawulezileyo.

• ifiva
• ubunzima bokuphefumla
• utshintsho kwintliziyo
• ukudinwa okanye ubuthathaka
• ukudideka

ICasirivimab kunye ne-imdevimab inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina lonke ixesha lokudibana nogqirha wakho.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga necasirivimab kunye nenaliti ye-imdevimab.

Kuya kufuneka uqhubeke nokuzahlula ngokokuyalelwa ngugqirha wakho kwaye ulandele iinkqubo zempilo zikawonkewonke ezinje ngokunxiba imaski, ukudibanisa ekuhlaleni, kunye nokuhlamba izandla rhoqo.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

I-American Society ye-Health-System Pharmacists, Inc.mele ukuba olu lwazi malunga ne-casirivimab kunye ne-imdevimab lwenziwa ngomgangatho ofanelekileyo wokhathalelo, nangokuhambelana nemigangatho yobungcali ebaleni. Abafundi bayalumkiswa ukuba indibaniselwano ye-casirivimab kunye ne-imdevimab ayilulo unyango oluvunyiweyo lwe-coronavirus isifo se-2019 (i-COVID-19) ebangelwa yi-SARS-CoV-2, kodwa endaweni yoko, iyaphandwa kwaye ngoku iyafumaneka phantsi, isigunyaziso sokusetyenziswa okungxamisekileyo kwe-FDA ( I-EUA) kunyango lwe-COVID-19 emnene ukuya kumodareyitha kwizigulana ezithile. Umbutho waseMelika woNyango lwezeMpilo-iiNkqubo zooSokhemisti, Inc. ayenzi bume okanye ziqinisekiso, zichaza okanye zichaziweyo, kubandakanya, kodwa kungaphelelanga apho, nakweyiphi na iwaranti echaziweyo yokurhweba kunye / okanye ukufaneleka kwinjongo ethile, ngokubhekisele kulwazi, ngakumbi iyazichaza zonke ezi ziqinisekiso. Abafundi bolwazi malunga ne-casirivimab kunye ne-imdevimab bayacetyiswa ukuba i-ASHP ayinaxanduva lwemali eqhubekayo yolwazi, ngazo naziphi na iimpazamo okanye ukushiywa, kunye / okanye naziphi na iziphumo ezivela ekusetyenzisweni kolwazi. Abafundi bayacetyiswa ukuba izigqibo ngokubhekisele kunyango lweziyobisi zizigqibo ezintsonkothileyo zonyango ezifuna isigqibo esizimeleyo, esichaziweyo sengcali efanelekileyo yokhathalelo lwempilo, kwaye ulwazi oluqulethwe kolu lwazi lubonelelwa ngeenjongo zolwazi kuphela. I-American Society ye-Health-System Pharmacists, Inc. ayikhuthazi okanye icebise ukusetyenziswa kwalo naliphi na ichiza. Olu lwazi malunga ne-casirivimab kunye ne-imdevimab akufuneki ukuba luqwalaselwe njengengcebiso yesigulana. Ngenxa yokutshintsha kolwazi lweziyobisi, uyacetyiswa ukuba ubonane nogqirha wakho okanye usokhemesti malunga nokusetyenziswa kweeklinikhi ezithile kunye nawo onke amayeza.

• UKUQHUBA-I-COV