Umbhali: Virginia Floyd
Umhla Wokudalwa: 10 Eyethupha 2021
Hlaziya Umhla: 14 Eyenkanga 2024
Anonim
VISION trial: subset efficacy analyses of tepotinib for NSCLC
Ividiyo: VISION trial: subset efficacy analyses of tepotinib for NSCLC

Umxholo

I-Tepotinib isetyenziselwa ukunyanga uhlobo oluthile lomhlaza wesifo somhlaza ongasencinci (i-NSCLC) ethe yasasazeka kwamanye amalungu omzimba kubantu abadala. I-Tepotinib ikudidi lwamayeza abizwa ngokuba yi-kinase inhibitors. Isebenza ngokuthintela isenzo seprotein engaqhelekanga ebonisa iiseli zomhlaza ukuba zande. Oku kunceda ukucothisa okanye ukunqanda ukusasazeka kweeseli zomhlaza.

I-Tepotinib iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye yonke imihla kunye nokutya. Thatha i-tepotinib malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-tepotinib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze.

Ukuba uyagabha emva kokuthatha i-tepotinib, musa ukuthatha enye idosi. Qhubeka neshedyuli yakho yesiqhelo.

Ugqirha wakho anganciphisa umthamo wakho okanye ayeke okwethutyana okanye ayeke isigxina unyango lwakho ngokuxhomekeke ekubeni unazo naziphi na iziphumo ebezingalindelekanga. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho nge tepotinib.


Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-tepotinib,

  • xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa itepotinib, naliphi na iyeza, okanye nasiphi na isithako kwiipilisi ze-tepotinib. Buza usokhemesti wakho uluhlu lwezithako.
  • xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye neemveliso zamayeza esintu} ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); indawo yokuhlala (iTybost); ikhonkco (Vaprisol); ii-corticosteroids; icyclosporine (Gengraf, Neoral); dabigatran (Pradaxa); efavirenz (Sustiva, eAtripla); indinavir; itraconazole (Onmel, Sporanox); ketoconazole; nevirapine (Viramune); phenobarbital; phenytoin (iDilantin, iPhenytek); i-posaconazole (Noxafil); irifabutin (Mycobutin); irifampin (Rifadin, Rimactane); i-ritonavir (iNorvir); i-saquinavir (i-Invirase); kunye netacrolimus (Prograf). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-tepotinib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
  • xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
  • xelela ugqirha wakho ukuba unengxaki yokuphefumla okanye yokuphefumla ngaphandle komhlaza wemiphunga okanye isifo sesibindi.
  • xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Akufanele ukhulelwe ngelixa uthatha i-tepotinib. Kuya kufuneka ukuba ube novavanyo lokukhulelwa ngaphambi kokuba uqale unyango, kwaye kuya kufuneka usebenzise ulawulo lokuzalwa ukuthintela ukukhulelwa ngexesha lonyango lwakho kwaye ubuncinci iveki enye emva kwethamo lakho lokugqibela. Ukuba uyindoda eneqabane lomfazi elinokuthi likhulelwe, kuya kufuneka usebenzise ulawulo lokuzalwa ukuthintela ukukhulelwa ngexesha lonyango kwaye ubuncinci iveki emva kwethamo lakho lokugqibela. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. I-Tepotinib inokulimaza umntwana wakho ongakazalwa. Ukuba wena okanye iqabane lakho ukhulelwe ngexesha lonyango lwakho kunye ne-tepotinib, biza ugqirha wakho ngokukhawuleza.
  • xelela ugqirha wakho ukuba uncelisa. Akufanele uncancise umntwana ngelixa uthatha i-tepotinib kwaye ubuncinci iveki enye emva kwedosi yakho yokugqibela.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.


Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba ngaba ngaphakathi kweeyure eziyi-8 zedosi yakho elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo rhoqo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Tepotinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • ukudumba kweengalo, izandla, iinyawo, okanye imilenze esezantsi
  • isicaphucaphu
  • urhudo
  • ukuqhina
  • ukugabha
  • Ukuphelelwa ngumdla wokutya
  • intlungu zesisu
  • ukudinwa
  • intlungu yesihlunu, edibeneyo, okanye yethambo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

  • ukuphefumla kancinci, umkhuhlane, okanye ukukhohlela
  • iintlungu kwindawo ephezulu yesisu; ukugruzuka okanye ukopha okungaqhelekanga; umchamo omnyama; ubumthubi besikhumba namehlo; okanye ukuphelelwa ngumdla wokutya

I-Tepotinib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.


Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-tepotinib. Ugqirha wakho uya ku-odola uvavanyo lwelebhu ngaphambi kokuba uqale unyango lwakho ukufumanisa ukuba umhlaza wakho unganyangwa nge-tepotinib.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • Tepmetko®
Ukuhlaziywa kokugqibela-03/15/2021

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