ITolbutamide

Umxholo

• Ngaphambi kokuba uthathe i-tolbutamide,
• Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso.
• I-Tolbutamide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:
• Iimpawu zokudlula ngaphezulu zinokubandakanya iimpawu zehypoglycemia kunye noku kulandelayo:

I-Tolbutamide isetyenziswa kunye nokutya kunye nokuzilolonga, kwaye ngamanye amaxesha ngamanye amayeza, ukunyanga i-2 yeswekile (imeko apho umzimba ungasebenzisi i-insulin ngesiqhelo kwaye, ngenxa yoko, ayinakho ukulawula isixa seswekile egazini). I-Tolbutamide ikudidi lwamayeza abizwa ngokuba yi-sulfonylureas. I-Tolbutamide yehlisa iswekile yegazi ngokubangela i-pancreas ukuba ivelise i-insulin (into yendalo efunekayo ukophula iswekile emzimbeni) kunye nokunceda umzimba ukuba usebenzise i-insulin ngokufanelekileyo. Eli yeza liza kunceda ukunciphisa iswekile yegazi kubantu abanemizimba evelisa i-insulin ngokwendalo. I-Tolbutamide ayisetyenziselwa ukunyanga i-1 yeswekile (imeko apho umzimba ungayivelisi i-insulin kwaye, ngenxa yoko, ayinakho ukulawula isixa seswekile esegazini) okanye isifo seswekile ketoacidosis (imeko enokubakho xa iswekile ephezulu yegazi inganyangwa ).

Ixesha elingaphezulu, abantu abanesifo seswekile kunye neswekile ephezulu yegazi banokuba neengxaki ezinzulu okanye ezisongela ubomi, kubandakanya isifo sentliziyo, ukubetha, iingxaki zezintso, ukonakala kwemithambo-luvo kunye neengxaki zamehlo. Ukuthatha amayeza, ukwenza utshintsho kwindlela yokuphila (umzekelo, ukutya, ukwenza umthambo, ukuyeka ukutshaya), kunye nokujonga iswekile yegazi rhoqo kunokunceda ukulawula isifo seswekile kunye nokuphucula impilo yakho. Olu nyango lunokunciphisa amathuba akho okuhlaselwa sisifo sentliziyo, ukubetha, okanye ezinye iingxaki ezinxulumene nesifo seswekile ezinje ngokusilela kwezintso, ukulimala kwentliziyo (ukubindeka, imilenze ebandayo okanye iinyawo; ukunciphisa amandla ezesondo kumadoda nabasetyhini), iingxaki zamehlo, kubandakanya notshintsho okanye ukulahleka kombono, okanye isifo seentsini. Ugqirha wakho kunye nabanye ababoneleli ngempilo bayakuthetha nawe ngeyona ndlela yokulawula isifo sakho seswekile.

I-Tolbutamide iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye ngemini kusasa. Xelela ugqirha wakho ukuba i-tolbutamide iyasicaphukisa isisu sakho. Ugqirha wakho unokukuxelela ukuba uthathe iidosi ezincinci ze-tolbutamide ngaphezu kwesinye ngosuku. Ukukunceda ukhumbule ukuthatha i-tolbutamide, yithathe malunga namaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-tolbutamide ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ugqirha wakho uya kuqala ngedosi esezantsi ye-tolbutamide kwaye ngokuthe ngcembe andise idosi yakho xa kufuneka njalo. Emva kokuba uthathe i-tolbutamide kangangexesha elithile, i-tolbutamide ayinakukulawula iswekile yegazi lakho njengoko ibenzile ekuqaleni konyango lwakho. Ugqirha wakho unokuhlengahlengisa idosi yamayeza akho njengoko kufuneka ukuze iyeza lisebenze ngcono kuwe. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani kwaye ukuba iziphumo zovavanyo lweswekile yegazi ziphezulu okanye zisezantsi kunesiqhelo nangaliphi na ixesha kunyango lwakho.

La mayeza ngamanye amaxesha amiselweyo kwezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-tolbutamide,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-tolbutamide, nawaphi na amanye amayeza, okanye naziphi na izithako kwi-tolbutamide. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya ii-anticoagulants ('igazi elincinci') njenge-warfarin (Coumadin); i-aspirin kunye nezinye iyeza ezichasayo (i-NSAIDs) ezinje nge-ibuprofen (Advil, Motrin) kunye ne-naproxen (Aleve, Naprosyn); ii-beta blockers ezinje nge-atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), kunye nepropranolol (Inderal); iicalcium block blockers ezifana neamlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, others), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop), nisold Sular), kunye neverapamil (Calan, Isoptin, Verelan); ichloramphenicol; umchamo ('iipilisi zamanzi'); i-fluconazole (i-Diflucan), unyango olungena endaweni yehomoni kunye nezinto zokucwangcisa zehomoni (iipilisi zolawulo lokuzalwa, iipatches, iiringi, ukufakelwa kunye nenaliti); i-insulin okanye amanye amayeza ukunyanga iswekile ephezulu yegazi okanye isifo seswekile; isoniazid (INH); I-MAO inhibitors ezifana ne-isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), kunye ne-tranylcypromine (iParnate); amayeza umbefu kunye nemikhuhlane; amayeza okugula ngengqondo kunye nesicaphucaphu; miconazole (Monistat); niacin; i-steroids yomlomo efana ne-dexamethasone (i-Decadron, i-Dexone), i-methylprednisolone (Medrol), kunye ne-prednisone (Deltasone); phenytoin (Dilantin); probenecid (iBenemid); iintlungu ze-salicylate ziyancipha njenge-choline magnesium trisalicylate, choline salicylate (Arthropan), diflunisal (Dolobid), magnesium salicylate (Doan's, others), kunye ne-salsalate (Argesic, Disalcid, Salgesic); i-sulfa antibiotics njenge co-trimoxazole (Bactrim, Septra); isulfasalazine (Azulfidine); kunye namayeza e-thyroid. Qiniseka ukuba uxelela ugqirha okanye usokhemesti ukuba uyeka ukuthatha nawaphi na amayeza ngelixa uthatha i-tolbutamide. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wanayo okanye wakha wanesiphene se-G6PD (imeko ezuzwe njengelifa ebangela ukutshatyalaliswa kwangaphambili kweeseli ezibomvu zegazi okanye ihememia). ukuba unengxaki yehomoni ebandakanya iadrenal, pituitary, okanye idlala lengqula; okanye ukuba unesifo sentliziyo, sezintso, okanye sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-tolbutamide, tsalela umnxeba ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-tolbutamide.
• buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kweziselo ezinxilisayo ngelixa uthatha i-tolbutamide. Utywala bunokwenza iziphumo ebezingalindelekanga zibi ngakumbi kwi-tolbutamide. Ukusela utywala ngelixa uthatha i-tolbutamide nako kunokubangela iimpawu ezinjengokugungxula (ukuba bomvu kobuso), intloko ebuhlungu, isicaphucaphu, ukugabha, iintlungu zesifuba, ubuthathaka, umbono ophuthileyo, ukudideka kwengqondo, ukubila, ukukrwitsha, ubunzima bokuphefumla kunye noxinzelelo.
• cwangcisa ukuthintela ukukhanya elangeni ngokungeyomfuneko okanye ixesha elide kunye nokunxiba impahla ekhuselayo, iiglasi zelanga kunye nescreen selanga. I-Tolbutamide inokwenza ulusu lwakho lubuthathaka kwilanga.
• buza ugqirha wakho ukuba wenzeni ukuba uyagula, uhlasele usulelo okanye umkhuhlane, amava oxinzelelo angaqhelekanga, okanye wenzakele. Ezi meko zinokuchaphazela iswekile yegazi lakho kunye nenani le-tolbutamide onokuyifuna.

Qiniseka ukuba ulandela yonke imithambo kunye nezincomo zokutya ezenziwe ngugqirha wakho okanye ugqirha otya ukutya. Kubalulekile ukutya ukutya okusempilweni, ukuzilolonga rhoqo, kwaye unciphise umzimba xa kukho imfuneko yoko.

Ngaphambi kokuba uqale ukuthatha i-tolbutamide, buza ugqirha ukuba kufuneka wenze ntoni xa ulibale ukuthatha idosi. Bhala ezi zikhombisi phantsi ukuze ubhekise kuzo kamva.

Njengomgaqo ngokubanzi, thabatha idosi ephosiweyo kwakamsinya nje ukuba uyikhumbule. Ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso.

I-Tolbutamide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukuzaliswa okuphezulu kwesisu
• isilungulela
• irhashalala
• intloko ebuhlungu
• utshintsho kwincasa

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• mthubi ulusu okanye amehlo
• izitulo ezikhanyayo
• umchamo omnyama
• iintlungu kwinxalenye ephezulu yesisu
• ukugruzuka okanye ukopha okungaqhelekanga
• urhudo
• ifiva
• umqala obuhkungu

I-Tolbutamide inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwisifundo esinye, abantu abathathe i-tolbutamide ukunyanga isifo seswekile kunokwenzeka ukuba babulawe ziingxaki zentliziyo kunabantu abanyangwa nge-insulin kunye notshintsho ekutyeni. Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-tolbutamide.

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nokukhanya, ubushushu obungaphaya, kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya iimpawu zehypoglycemia kunye noku kulandelayo:

• ukuxhuzula
• ukulahleka kwengqondo

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Iswekile yakho yegazi kunye namanqanaba eswekile yomchamo kufuneka ihlolwe rhoqo ukumisela impendulo yakho kwi-tolbutamide. Ugqirha wakho angayalela ezinye iimvavanyo zelebhu, kubandakanya i-hemoglobin ye-glycosylated (HbA1c), ukujonga impendulo yakho kwi-tolbutamide. Ugqirha wakho uya kukuxelela nendlela yokujonga impendulo yakho kolu nyango ngokulinganisa igazi lakho okanye umchamo wamanqanaba eswekile ekhaya. Landela le miyalelo ngononophelo.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha i-tolbutamide.

Kufuneka usoloko unxibe isacholo esichaza isifo seswekile ukuze uqiniseke ukuba ufumana unyango olufanelekileyo ngexesha likaxakeka.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Orinase^®¶

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