Colchicine

Umxholo

• Ngaphambi kokuba uthathe i-colchicine,
• I-Colchicine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezi zimpawu zilandelayo zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, yeka ukuthatha i-colchicine kwaye ubize ugqirha ngoko nangoko:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

I-Colchicine isetyenziselwa ukuthintela uhlaselo lwe-gout (ngequbuliso, iintlungu eziqatha kwilungu elinye okanye nangaphezulu ezibangelwa ngamanqanaba aphezulu ngokungaqhelekanga wento ebizwa ngokuba yi-uric acid egazini) kubantu abadala. I-Colchicine (Colcrys) ikwasetyenziselwa ukudambisa iintlungu kuhlaselo lwe-gout xa zisenzeka. IColchicine (Colcrys) ikwasetyenziselwa ukunyanga usapho lweMeditera fever (FMF; imeko engokwemvelo ebangela iziqatha zomkhuhlane, iintlungu kunye nokudumba kwendawo yesisu, imiphunga kunye namalungu) kubantu abadala nakubantwana abaneminyaka emi-4 nangaphezulu. I-Colchicine ayisiyiyo into yokuphelisa iintlungu kwaye ayinakusetyenziselwa ukunyanga iintlungu ezingabangelwa yi-gout okanye i-FMF. I-Colchicine ikudidi lwamayeza abizwa ngokuba ziiarhente ezichasene ne-gout. Isebenza ngokumisa iinkqubo zendalo ezibangela ukudumba kunye nezinye iimpawu zentsholongwane kunye ne-FMF.

IColchicine iza njengecwecwe kunye nesisombululo (ulwelo; iGloperba) ukuyithatha ngomlomo kunye nangaphandle kokutya. Xa i-colchicine isetyenziselwa ukuthintela uhlaselo lwe-gout okanye ukunyanga i-FMF, ihlala ithathwa kanye okanye kabini ngemini. Xa i-colchicine (Colcrys) isetyenziselwa ukudambisa iintlungu kuhlaselo lwe-gout, idosi enye ihlala ithathwa kulwalamano lokuqala kwaye okwesibini, idosi encinci ithathwa iyure enye kamva. Ukuba awufumani kuphumla okanye uhlaselwe kwiintsuku ezimbalwa emva konyango, thetha nogqirha wakho ngaphambi kokuba uthathe amayeza awongezelelekileyo. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-colchicine ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Kubalulekile ukusebenzisa isirinji yomlomo (isixhobo sokulinganisa) ukulinganisa ngokuchanekileyo inani elichanekileyo lolwelo kwidosi nganye; Sukusebenzisa icephe lasekhaya.

Ukuba uthatha i-colchicine (Colcrys) ukunyanga i-FMF, ugqirha wakho unokukuqala kwidosi ephantsi kwaye ngokuthe ngcembe wandise idosi yakho. Ugqirha wakho unokunciphisa umthamo wakho ukuba unemiphumo emibi.

Ukuba uthatha i-colchicine ukuthintela uhlaselo lwe-gout, tsalela umnxeba kwangoko ukuba ufumana uhlaselo lwe-gout ngexesha lonyango lwakho. Ugqirha wakho unokukuxelela ukuba uthathe idosi eyongezelelweyo ye-colchicine, elandelwa yidosi encinci kwiyure enye kamva. Ukuba uthatha imithamo eyongezelelweyo ye-colchicine ukunyanga uhlaselo lwe-gout, akufuneki uthathe idosi yakho elandelayo ecwangcisiweyo ye-colchicine de kudlule ubuncinci iiyure ezili-12 okoko uthathe idosi engaphezulu.

I-Colchicine inokuthintela uhlaselo lwesifo kunye nokulawula i-FMF kuphela ukuba uthatha iyeza. Qhubeka nokuthatha i-colchicine nokuba uziva uphilile. Ungayeki ukuthatha i-colchicine ngaphandle kokuthetha nogqirha wakho.

La mayeza angamiselwa ezinye izinto. Buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-colchicine,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-colchicine, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-colchicine okanye isisombululo. Buza ugqirha wakho okanye usokhemesti okanye ujonge isikhokelo sonyango kuluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, iimveliso zesondlo, kunye nezongezo zemifuno ozithathayo, ozithathileyo kwiintsuku ezili-14 ezidlulileyo, okanye uceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-antibiotics efana ne-azithromycin (Zithromax), i-clarithromycin (i-Biaxin), i-erythromycin (i-EES, i-E-Mycin), i-telithromycin (i-Ketek; ayifumaneki e-US); ii-antifungals ezifana ne-fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), kunye ne-posaconazole (Noxafil); Aprepitant (Hlomela); cholesterol-ukunciphisa amayeza (ii-statins) ezinjenge-atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor), pravastatin (Pravachol), kunye ne-simvastatin (Zocor); i-cyclosporine (iGenGraf, iNeoral, iSandimmune); idigoxin (iDigitek, iLanoxin); diltiazem (Cardizem, Dilacor, Tiazac, nabanye); ii-fibrate ezinje nge-bezafibrate, fenofibrate (Antara, Lipofen), kunye gemfibrozil (Lopid); amayeza e-HIV okanye i-AIDS njenge-amprenavir (Agenerase), atazanavir (Reyataz), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (eKaletra, eNorvir), kunye ne-saquinavir (Invirase); nefazodone; I-ranolazine (iRanexa); Kunye neverapamil (Calan, Covera, Isoptin, Verelan). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-colchicine, ke qiniseka ukuxelela ugqirha wakho malunga nawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba ukhe waba nesifo sezintso okanye sesibindi. Ugqirha wakho uya kukuxelela ukuba ungathathi i-colchicine ukuba uthatha amanye amayeza okanye ukuba unesifo sezintso nesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-colchicine, tsalela ugqirha wakho.

Musa ukuyitya i-grapefruit okanye usele ijusi yeziqhamo ngexesha lonyango lwakho nge-colchicine.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Ukuba uthatha i-colchicine rhoqo kwaye phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo rhoqo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

Nangona kunjalo, ukuba uthatha i-colchicine (Colcrys) ukunyanga uhlaselo lwe-gout eyenzekileyo ngelixa uthatha i-colchicine ukunqanda uhlaselo lwe-gout kwaye ulibale ukuthatha idosi yesibini, thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Emva koko linda ubuncinci iiyure ezili-12 ngaphambi kokuba uthathe idosi elandelayo ecwangcisiweyo ye-colchicine.

I-Colchicine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezi zimpawu zilandelayo zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• urhudo
• isisu esibuhlungu okanye iintlungu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, yeka ukuthatha i-colchicine kwaye ubize ugqirha ngoko nangoko:

• iintlungu zemisipha okanye ubuthathaka
• ukuba ndindisholo okanye ukurhawuzelela iminwe okanye iinzwane
• ukugruzuka okanye ukopha okungaqhelekanga
• umqala obuhlungu, umkhuhlane, ukubanda, kunye neminye imiqondiso yosulelo
• ubuthathaka okanye ukudinwa
• ukuphaphatheka okanye ukungwevu kwemilebe, ulwimi, okanye iintende

I-Colchicine inokunciphisa ukuzala emadodeni. Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-colchicine.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa libanda, yiya kwigumbi elikhawulezileyo lesibhedlele ngokukhawuleza. Ukuthatha i-colchicine eninzi kunokubangela ukufa.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• isisu esibuhlungu
• isicaphucaphu
• ukugabha
• urhudo
• ukugruzuka okanye ukopha okungaqhelekanga
• umqala obuhlungu, umkhuhlane, ukubanda, kunye neminye imiqondiso yosulelo
• ukuphaphatheka okanye ukungwevu kwemilebe, ulwimi, okanye iintende
• ukuphefumla okucothayo
• yacotha okanye yamisa ukubetha kwentliziyo

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unokuyalela iimvavanyo ezithile zebhu ukujonga impendulo yakho kwi-colchicine.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Iifayile^®
• IGloperba^®