Inaliti yeVincristine

Umxholo

• Ngaphambi kokufumana uVincristine,
• IVincristine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO, kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

IVincristine kufuneka ilawulwe kuphela emthanjeni. Nangona kunjalo, inokuvuza kwizicubu ezijikelezileyo kubangele ukucaphuka okukhulu okanye ukonakala. Ugqirha wakho okanye umongikazi uya kubeka esweni indawo yakho yolawulo ngale mpendulo. Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: iintlungu, ukurhawuzelela, ukuba bomvu, ukudumba, iblisters, okanye izilonda kwindawo apho lalifakwe khona iyeza.

UVincristine kufuneka anikwe kuphela phantsi kweliso likagqirha onamava ekusebenziseni amayeza e-chemotherapy.

I-Vincristine isetyenziselwa ukudibanisa namanye amayeza e-chemotherapy ukunyanga iintlobo ezithile ze-leukemia (umhlaza weeseli ezimhlophe zegazi), kubandakanya i-leukemia ye-myeloid (AML, ANLL) kunye ne-leukemia ye-lymphoblastic (ALL), i-Hodgkin's lymphoma (isifo sikaHodgkin), kwaye -Hodgkin's lymphoma (iintlobo zomhlaza eziqala kuhlobo lweeseli ezimhlophe zegazi ezihlala zilwa nosulelo). I-Vincristine ikwasetyenziswa ngokudibeneyo namanye amayeza e-chemotherapy ukunyanga ithumba le-Wilms (uhlobo lomhlaza wezintso olwenzeka ebantwaneni), i-neuroblastoma (umhlaza oqala kwiiseli zemithambo-luvo kwaye kwenzeka ikakhulu ebantwaneni), kunye ne-rhabdomyosarcoma (umhlaza owenza izihlunu. ebantwaneni). UVincristine ukwiklasi yamayeza abizwa ngokuba yiincinc alkaloids. Isebenza ngokunciphisa okanye ukumisa ukukhula kweeseli zomhlaza emzimbeni wakho.

UVincristine uza njengesisombululo (ulwelo) sokutofelwa ngaphakathi (emthanjeni) ngugqirha okanye ngumongikazi kwiziko lonyango. Ihlala inikwa kube kanye ngeveki. Ubude bonyango buxhomekeke kwiintlobo zamachiza owathathayo, ukuba umzimba wakho uphendula njani kuwo, kunye nohlobo lomhlaza onawo.

Ugqirha wakho unokufuna ukulibazisa unyango lwakho okanye utshintshe idosi yakho ukuba uneziphumo ebezingalindelekanga ezithile. Kubalulekile ukuba uxelele ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho ngenaliti yeVincristine.

Ugqirha wakho angakuxelela ukuba uthathe isilungelelanisi sesitulo okanye i-laxative ukunceda ukuthintela ukuqunjelwa ngexesha lonyango lwakho ngenaliti ye-vincristine.

UVincristine ngamanye amaxesha usetyenziselwa ukunyanga iintlobo ezithile zamathumba obuchopho, iintlobo ezithile zomhlaza wemiphunga, uninzi lwe-myeloma (uhlobo lomhlaza womongo wethambo), i-lempemia ye-lymphocytic engapheliyo (i-CLL; uhlobo lomhlaza weeseli ezimhlophe zegazi), i-Kaposi's I-sarcoma (uhlobo lomhlaza olwenza ukuba izicwili ezingaqhelekanga zikhule kwiindawo ezahlukeneyo zomzimba) ezinxulumene ne-immunodeficiency syndrome (i-AIDS), i-Ewings sarcoma (uhlobo lomhlaza emathanjeni okanye kwimisipha), kunye nezidumbu zohlobo oluthile lwesifo somhlaza. ezenzeka ngaphakathi esibelekweni somfazi ngelixa ekhulelwe). UVincristine ngamanye amaxesha usetyenziselwa ukunyanga i-thrombotic thrombocytopenic purpura (TPP; isifo segazi esenza ukuba amahlwili egazi enze kwimithambo yegazi encinci emzimbeni). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana uVincristine,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-vincristine, nawaphi na amanye amayeza, okanye nasiphi na isithako se-vincristine. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: aprepitant (Emend); carbamazepine (Tegretol); izinto ezithile zokubulala ukungunda ezifana ne-itraconazole (Sporanox), ketoconazole (Nizoral), voriconazole (Vfend), kunye ne-posaconazole (Noxafil); i-clarithromycin (i-Biaxin, kwi-Prevpac); iDarifenacin (Enablex); dexamethasone (Decadron); ifesoterodine (Toviaz); I-HIV protease inhibitors kubandakanya atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, e Kaletra), kunye ne-saquinavir (Invirase); nefazodone; Oxybutynin (Ditropan, Ditropan XL, Oxytrol); phenobarbital; phenytoin (Dilantin); irifabutin (Mycobutin); irifampin (Rifadin, Rimactane); irifapentine (Priftin); i-solifenacin (Vesicare); telithromycin (Ketek); itrospium (iSanctura); okanye i-tolterodine (Detrol, Detrol LA). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ukhe wanesifo esichaphazela imithambo-luvo yakho. Ugqirha wakho usenokungafuni ukuba ufumane inaliti yeVincristine.
• xelela ugqirha wakho ukuba ngaba unayo okanye wakhe wanayo na imitha ye-radiation (x-ray), ukuba unesifo, okanye ukuba unesifo semiphunga okanye sesibindi.
• Kuya kufuneka uyazi ukuba i-vincristine inokuphazamisa umjikelo oqhelekileyo wokuya exesheni (exesheni) kwabasetyhini kwaye unokuyeka okwethutyana okanye ngokusisigxina ukuyeka ukuvelisa isidoda emadodeni. Tshela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ukuncancisa. Akufanele ukhulelwe okanye uncancise ngelixa ufumana inaliti ye-vincristine. Ukuba ukhulelwa ngelixa ufumana inaliti yeVincristine, tsalela umnxeba ugqirha wakho. UVincristine unokulimaza umbungu.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

IVincristine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• izilonda emlonyeni nasemqaleni
• ukuphelelwa ngumdla wokutya okanye ubunzima
• isisu esibuhlungu
• urhudo
• intloko ebuhlungu
• ukulahleka kweenwele

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO, kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

• urhwebo
• irhashalala
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya
• ukuqhina
• ukonyuka okanye ukuncipha kokuchama
• ukudumba kobuso, iingalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukopha okungaqhelekanga okanye ukugruzuka
• ukudinwa okungaqhelekanga okanye ubuthathaka
• intlungu, ukuba ndindisholo, ukutshisa, okanye ukubetha ezandleni okanye ezinyaweni
• ukuhamba nzima okanye ukuhamba ungazinzanga
• intlungu yesihlunu okanye edibeneyo
• utshintsho olukhawulezileyo kumbono, kubandakanya ukulahleka kombono
• ukulahlekelwa kwindlebe
• isiyezi
• ukulahleka kwamandla okuhambisa izihlunu kunye nokuziva ulilungu lomzimba
• Ukudakumba okanye ukulahleka kokubanakho ukuthetha ngokuvakalayo
• ukuxhuzula
• iintlungu zomhlathi
• umkhuhlane, umqala obuhlungu, ingqele, okanye ezinye iimpawu zosulelo

UVincristine unokunyusa umngcipheko wokuba uphuhlise eminye imihlaza. Thetha nogqirha wakho malunga nemingcipheko yokufumana inaliti ye-vincristine.

IVincristine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• ukuxhuzula
• ukuqhina okunzima
• isisu esibuhlungu
• ukopha okungaqhelekanga okanye ukugruzuka

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-vincristine.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• UOncovin^®¶
• UVincasar^® I-PFS
• UVincrex^®¶

• I-Leurocristine Sulfate
• I-LCR
• VCR

^¶ Le mveliso inophawu akusekho kwimarike. Ezinye iindlela ezinokubakho zinokubakho.