Umbhali: Clyde Lopez
Umhla Wokudalwa: 21 Eyekhala 2021
Hlaziya Umhla: 15 Eyenkanga 2024
Anonim
Flecainide and Propafenone - Class IC Antiarrhythmics Mechanism of Action, Side Effects & Indication
Ividiyo: Flecainide and Propafenone - Class IC Antiarrhythmics Mechanism of Action, Side Effects & Indication

Umxholo

Kwizifundo zeklinikhi, abantu ababesandula ukuba nesifo sentliziyo kwaye bathatha amayeza athile okubetha kwentliziyo okungaqhelekanga afana nepropafenone kunokwenzeka ukuba bafe kunabantu abangakhange bathathe iyeza elinye. Ipropafenone inokubangela ukuba kubekho ukubetha kwentliziyo ngokungafanelekanga kwaye kwandise umngcipheko wokufa kwezigulana ezithile. Xelela ugqirha wakho ukuba ukhe wahlaselwa sisifo sentliziyo kule minyaka mibini idlulileyo okanye ukuba unesifo sentliziyo.

Ngenxa yomngcipheko wokuthatha ipropafenone, kufuneka isetyenziselwe kuphela ukunyanga ukubetha kwentliziyo ngokungafanelekanga okusongela ubomi. Thetha nogqirha wakho malunga nomngcipheko wokuthatha ipropafenone.

Ugqirha wakho unokukuvavanya kwaye unoku-odola uvavanyo oluthile lweelebhu kunye novavanyo lwe-electrocardiogram (EKG) ukujonga impendulo yomzimba wakho kwipropafenone. Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri.

Ipropafenone isetyenziselwa ukunyanga i-arrhythmia (ukubetha kwentliziyo ngokungaqhelekanga) kunye nokugcina ukubetha kwentliziyo okuqhelekileyo. Ipropafenone ikudidi lwamayeza abizwa ngokuba yi-antiarrhythmics. Isebenza ngokusebenza kwimisipha yentliziyo ukuphucula isingqi sentliziyo.


Ipropafenone iza njengecwecwe kunye nokukhululwa okwandisiweyo (ixesha elide) njengepilisi oza kuyithatha ngomlomo. Ithebhulethi ihlala ithathwa kathathu ngemini, kube kanye kwiiyure ezisibhozo. I-capsule ekhutshiweyo ihlala ithathwa kabini ngemini, kube kanye kwiiyure ezili-12, kunye okanye ngaphandle kokutya. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha ipropafenone ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya zonke iifomsile; musa ukutyumza okanye ukuvula iifomsile okanye ukwahlula iziqulatho zephilisi kwiqondo elingaphezulu kwesinye.

Ungaqala ukuthatha ipropafenone esibhedlele ukuze ugqirha wakho akujongisise ngononophelo njengoko umzimba wakho uqhela amayeza. Ugqirha wakho unokukuqala ngedosi esezantsi yepropafenone kwaye ngokuthe ngcembe wandise idosi yakho, hayi rhoqo rhoqo kube kanye kwiintsuku ezintlanu.

Ipropafenone inokulawula ukubetha kwentliziyo yakho ngokungaqhelekanga, kodwa ayizukuyinyanga. Qhubeka nokuthatha ipropafenone nokuba uziva uphilile. Sukuyeka ukuthatha ipropafenone ngaphandle kokuthetha nogqirha wakho. Ukubetha kwentliziyo yakho kunokuba yinto engaqhelekanga ukuba uyeka ngequbuliso ukuthatha ipropafenone.


Eli yeza akufuneki limiselwe ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe ipropafenone,

  • xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana nepropafenone, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi zeepropafenone okanye iipilisi ezandisiweyo zokukhululwa. Buza ugqirha wakho okanye usokhemesti uluhlu lwezithako.
  • xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-anticoagulants ('i-blood thinner') efana ne-warfarin (Coumadin); ii-antibiotics ezithile ezifana ne-azithromycin (Zithromax), i-clarithromycin (i-Biaxin, kwi-Prevpac), kunye ne-erythromycin (E.E.S., ezinye); i-antihistamines; ii-beta-blockers ezinjenge-atenolol (Tenormin), i-carteolol (iCartrol), i-labetalol (i-Normodyne, i-Trandate), i-metoprolol (i-Lopressor), i-nadolol (i-Corgard), i-propranolol (Inderal), i-sotalol (i-Betapace) kunye ne-timolol (i-Blocadren); ezinye izinto ezichasayo ezifana ne-desipramine (Norpramin) kunye ne-imipramine (Tofranil); i-cimetidine (iTagamet); i-cisapride (Propulsid) (ayifumaneki e-U.S.); idigoxin (Lanoxin); haloperidol (iHaldol); ketoconazole (Nizoral); lidocaine; amayeza okubetha kwentliziyo ngokungaqhelekanga afana ne-amiodarone (Cordarone, Pacerone), bepredil (ayifumaneki e-U.S), dofetilide (Tikosyn), disopyramide (Norpace), ibutilide (Corvert), procainamide, kunye nequinidine (Quinaglute, abanye). amayeza okugula ngengqondo kunye nesicaphucaphu; uluhlu lwezinto (Alli, Xenical); i-ritonavir (i-Norvir); i-rifampin (iRifadin, iRimactane); i-saquinavir (i-Invirase); i-serotonin reuptake inhibitors (i-SSRIs) ekhethiweyo efana ne-fluoxetine (Prozac, Sarafem, kwi-Symbyax), i-paroxetine (Paxil, Pexeva) kunye ne-sertraline (Zoloft); kunye ne-venlafaxine (Effexor).
  • xelela ugqirha wakho ukuba unorhudo olugqithisileyo, ukubila, ukugabha, ukuphelelwa ngumdla wokutya, okanye ukuncipha kwenxano kwaye ukuba ukhe wabetha intliziyo kancinci; uxinzelelo lwegazi oluphantsi; amanqanaba asezantsi okanye aphezulu esodiyam, i-potassium, i-chloride, okanye i-bicarbonate egazini lakho; ukumelwa yintliziyo; Isifuba okanye nayiphi na imeko ebangela ukuba umoya wakho ube mxinwa. Ugqirha wakho unokukuxelela ukuba ungathathi ipropafenone.
  • ukongeza kwezi meko zidweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO, xelela ugqirha wakho ukuba ukhe wanayo okanye ukhe wanayo pacemaker; i-myasthenia gravis (ukuphazamiseka kwenkqubo yemithambo-luvo ebangela ubuthathaka bemisipha), okanye isifo sesibindi okanye sezintso,
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa uthatha ipropafenone, tsalela umnxeba ugqirha wakho.
  • ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha ipropafenone.
  • Kuya kufuneka uyazi ukuba eli yeza linokukwenza wozele okanye ube nesiyezi. Sukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela ekuchaphazela ngayo.
  • xelela ugqirha wakho ukuba usebenzisa iimveliso zecuba. Ukutshaya icuba kunokunciphisa ukusebenza kweli yeza.

Thetha nogqirha wakho malunga nokutya ukutya kunye neetyuwa ezithatha indawo ene potassium.


Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yamagilebhisi ngelixa uthatha eli yeza.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi yakho elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

Ipropafenone inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • isiyezi
  • umlomo owomileyo
  • intloko ebuhlungu
  • isicaphucaphu
  • ukugabha
  • urhudo
  • ukuqhina
  • Ukuphelelwa ngumdla wokutya
  • incasa engaqhelekanga emlonyeni
  • irhasi
  • ukudinwa
  • ixhala
  • ukungaboni kakuhle
  • ukushukuma okungalawulekiyo kwilungu lomzimba
  • ubunzima bokulala okanye ukulala
  • ubunzima ngokulungelelanisa

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

  • ubunzima bokuphefumla
  • ukuvutha
  • iintlungu zesifuba
  • entsha okanye eqhubeka ukubetha kwentliziyo engaqhelekanga
  • ukucotha, ukukhawuleza, okanye ukubetha kwentliziyo
  • ukudumba kwezandla, iinyawo, amaqatha okanye imilenze esezantsi
  • ngequbuliso, ukuzuza ubunzima okungachazwanga
  • isiqaqa
  • irhashalala
  • umkhuhlane ongachazwanga, ukugodola, ubuthathaka, okanye umqala obuhlungu

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

  • ukudinwa
  • ukubetha kwentliziyo kancinci okanye okungaqhelekanga
  • ukuxhuzula

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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  • Rythmol® SR
Ukuhlaziywa kokugqibela-01/15/2018

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