Ukuchaphazeleka kweHepatitis C engapheliyo: Ukuqonda ukhetho lwakho kunyango

Umxholo

• Unyango lwe-hepatitis C ebukhali
• Unyango lwe-hepatitis C engapheliyo
• Ukufakelwa kwesibindi
• Thetha nogqirha wakho

IHepatitis C sisifo esichaphazela isibindi. Ukuhlala ne-hepatitis C ixesha elide kungonakalisa isibindi sakho ukuya kuthi ga apho kungasebenzi kakuhle. Unyango lwakwangoko lunokunceda ukukhusela isibindi sakho kunye nokugcina umgangatho wobomi bakho.

Oogqirha bahlula i-hepatitis C ibe ziindidi ezimbini ngokusekwe kwimeko leyo:

• Acute hepatitis C linqanaba lokuqala xa ubunesifo sokudumba kwesibindi kangangesithuba esingaphantsi kweenyanga ezintandathu.
• I-hepatitis C engapheliyo luhlobo lwexesha elide, okuthetha ukuba unemeko kangangeenyanga ezintandathu. Ukuya kuthi ga kubantu abane-hepatitis C ekugqibeleni baya kuphuhlisa uhlobo lwesifo esinganyangekiyo.

Ugqirha wakho uza kuncoma unyango olusekwe kuhlobo lwe-hepatitis C onayo. Ukuqonda ukhetho lwakho lonyango kuya kukunceda wenze izigqibo unolwazi.

Unyango lwe-hepatitis C ebukhali

Ukuba une-hepatitis C ebukhali, akuyomfuneko ukuba uyinyange ngoko nangoko. Kubantu abanesi sifo, siya kuzicacisa sodwa ngaphandle konyango.

Uya kudinga ukubekwa esweni, nangona kunjalo. Ugqirha wakho uya kukunika uvavanyo lwegazi lwe-HCV RNA rhoqo kwiiveki ezine ukuya kwezisibhozo malunga neenyanga ezintandathu. Olu vavanyo lubonisa ukuba intsholongwane ye-hepatitis C (HCV) ingakanani kwigazi lakho.

Ngeli xesha, usenokudlulisela intsholongwane kwabanye ngokudibana kwegazi negazi. Gwema ukwabelana okanye ukusebenzisa kwakhona iinaliti. Umzekelo, oku kubandakanya xa kusenziwa umvambo okanye ukugqojozwa kwindawo engalawulwa, okanye ukujova iziyobisi. Ngexesha lokwabelana ngesondo, sebenzisa ikhondom okanye enye indlela yothintelo lolawulo lokuzalwa ukunqanda ukudlulisela intsholongwane kwabanye.

Ukuba intsholongwane iyasuswa ngeenyanga ezintandathu, awuyi kufuna ukunyangwa. Kodwa kubalulekile ukuthatha amanyathelo okuthintela ukosuleleka yintsholongwane kwakhona kwixa elizayo.

Unyango lwe-hepatitis C engapheliyo

Uvavanyo lwegazi oluqinisekileyo lwe-HCV RNA emva kweenyanga ezintandathu kuthetha ukuba unesifo se-hepatitis C esinganyangekiyo. Uya kudinga unyango ukunqanda intsholongwane ekonakaliseni isibindi sakho.

Olona nyango luphambili lusebenzisa amayeza antiviral ukuyicoca intsholongwane egazini lakho. Amachiza amatsha antiviral anokuphilisa ngaphezu kwabantu abane-hepatitis C. engapheliyo.

Ugqirha wakho uya kukhetha iyeza lokulwa intsholongwane okanye indibaniselwano yamachiza ngokusekwe kwinani lomonakalo wesibindi onayo, loluphi unyango obukhe wanalo kwixa elidlulileyo, kwaye loluphi uhlobo lwe-hepatitis C onalo. Kukho ii-genotypes ezintandathu. Uhlobo ngalunye luphendula kumayeza athile.

Amachiza antiviral avunyelwe yi-FDA ukunyanga i-hepatitis C engapheliyo ibandakanya:

• I-daclatasvir / sofosbuvir (iDaklinza) -i-genotypes 1 kunye ne-3
• I-elbasvir / grazoprevir (iZepatier) -i-genotypes 1 kunye ne-4
• glecaprevir / pibrentasvir (Mavyret) - genotypes 1, 2, 5, 6
• I-ledipasvir / sofosburir (Harvoni) -i-genotypes 1, 4, 5, 6
• ombitasvir / paritaprevir / ritonavir (Technivie) -uhlobo lwe-4
• ombitasvir / paritaprevir / ritonavir kunye nedasabuvir (Viekira Pak) - genotypes 1a, 1b
• simeprevir (Olysio) - uhlobo 1
• isofosbuvir / velpatasvir (Epclusa) -izonke ii-genotypes
• Sofosbuvir (Sovaldi) -izo zonke ii-genotypes
• Sofosbuvir / velpatasvir / voxilaprevir (Vosevi) -izonke ii-genotypes

I-Peginterferon alfa-2a (Pegasys), i-peginterferon alfa-2b (Pegintron), kunye ne-ribavirin (iCopegus, iRebetol, iRibasphere) ebezisetyenziswa njengonyango oluqhelekileyo lwe-hepatitis C. enganyangekiyo. Nangona kunjalo, bathathe ixesha elide ukusebenza kwaye bahlala ukunyanga intsholongwane. Baye babangela iziphumo ebezingalindelekanga ezinje ngomkhuhlane, ukugodola, ukulahleka kwesidlo kunye nomqala obuhlungu.

Namhlanje, i-peginterferon alfa kunye ne-ribavirin zisetyenziswa ngokufuthi kuba amachiza amatsha antiviral ayasebenza ngakumbi kwaye abangela iziphumo ebezingalindelekanga ezimbalwa. Kodwa ukuhlanganiswa kwe-peginterferon alfa, i-ribavirin, kunye ne-sofosbuvir kusekho unyango oluqhelekileyo kubantu abane-hepatitis C ye-genotypes 1 no-4.

Uya kuthatha amayeza e-hepatitis iiveki ezi-8 ukuya kwezi-12. Ngexesha lonyango, ugqirha wakho uya kukunika uvavanyo lwegazi ngamaxesha athile ukulinganisa ubungakanani bentsholongwane ye-hepatitis C eseleyo kwigazi lakho.

Injongo kukuba kungabikho mkhondo wentsholongwane egazini lakho ubuncinci kwiiveki ezili-12 emva kokugqiba unyango. Oku kubizwa ngokuba yimpendulo eqhubekayo ye-virologic, okanye i-SVR. Oko kuthetha ukuba unyango lwakho lube yimpumelelo.

Ukuba unyango lokuqala uzama alusebenzi, ugqirha wakho unokukunika ichiza elahlukileyo elinokuba neziphumo ezingcono.

Ukufakelwa kwesibindi

I-Hepatitis C yonakalisa kwaye ibangele isibindi. Ukuba uhlala nesi sifo iminyaka emininzi, isibindi sakho sinokonakaliswa ukuya kuthi ga apho singasebenziyo. Ngelo xesha, ugqirha wakho unokucebisa ukufakelwa kwesibindi.

Ukufakelwa kwesibindi kususa isibindi sakho esidala kwaye kukufaka endaweni entsha, esempilweni. Rhoqo isibindi sivela kumnikeli oswelekileyo, kodwa ukufakelwa kwabanikeli ngokuphila nako kunokwenzeka.

Ukufumana isibindi esitsha kuya kukunceda uzive ungcono, kodwa ayizukuyinyanga i-hepatitis C yakho. Ukusebenzela ukunyanga intsholongwane kunye nokufezekisa i-SVR, kusafuneka uthathe iyeza le-antiviral elihambelana nesifo sakho se-genotype.

Thetha nogqirha wakho

Namhlanje, unyango olutsha lwe-antiviral luyanceda ukunyanga abantu abaninzi abane-hepatitis C kunakwiminyaka edlulileyo. Ukuba une-hepatitis C okanye unokuba semngciphekweni, qiniseka ukubona ugqirha wakho. Banokukuvavanyela intsholongwane kwaye babone ukuba loluphi uhlobo lwehepatitis C onokuba unayo. Ukuba ufuna unyango, ugqirha unokukunceda wenze isicwangciso sonyango sokulawula i-hepatitis C kunye nokusebenza kunyango.