Yintoni iAkinesia?

Umxholo

• Iakinesia engekazalwa
• I-Akinesia kunye nedyskinesia: Uyintoni umahluko?
• Iimpawu
• Unyango
• Amayeza
• Izikhuthazi ezinokufakwa
• Ngaphaya kwekhawunta
• Olunye unyango kunye nonyango lwasekhaya
• Oonobangela kunye nemingcipheko
• Imbonakalo

Akinesia

I-Akinesia ligama lokulahleka kwamandla okuhambisa izihlunu zakho ngokuzithandela. Ihlala ichazwa njengeempawu zesifo sikaParkinson's (PD). Ingabonakala njengophawu lwezinye iimeko, nazo.

Olunye lweempawu ezixhaphakileyo zeakinesia “yingqele.” Oku kuthetha ukuba indawo enye okanye ezingaphezulu zomzimba wakho azisakwazi ukuhamba ngenxa yesimo se-neurological, njengePD. Ezi meko zibangela iiseli zemithambo-luvo (ii-neurons) kumaziko okuhamba kwengqondo yakho ukuba buthathaka kwaye afe. Emva koko ii-neurons azisakwazi ukuthumela imiqondiso kwimithambo-luvo nakwimisipha. Oku kunokubangela ukuba uphulukane namandla akho okulawula izihlunu zakho. Oku kunokubandakanya izihlunu ebusweni bakho, izandla, imilenze, okanye ezinye izihlunu ozisebenzisa yonke imihla.

I-Akinesia kunye neemeko ezininzi ezibangela ukuba ziqhubeke. Uninzi lweemeko ziqhubeka kwaye azinyangeki, kodwa ayizizo zonke. I-hypothyroidism ebukhali inokubangela ukubuyela kwimeko yesiqhelo kwi-akinetic syndrome. Iziyobisi ezibangelwa yi-parkinsonism zinokubuyiselwa umva.

Unyango kunye namayeza okucothisa ukuqhubela phambili kwe-akinesia kunye neemeko ze-neurological ezinje ngePD ziyafumaneka. Banokukunceda ukunciphisa umda kwiakinesia onayo kubomi bakho bemihla ngemihla.

Iakinesia engekazalwa

I-Akinesia inokwenzeka kwimveku esibelekweni. Le meko ibizwa ngokuba yi-fetal akinesia. Kule meko, iimveku azishukumi njengoko kufanelekile. Le meko inokwenzeka nezinye iimpawu. Imiphunga engekazalwa engekakhuli kakuhle okanye umntwana angazalwa enobuso obungaqhelekanga. Ezi mpawu ziyaziwa njengokulandelelana komntwana oksia deformation (FADS). Oku kunokuba neziphumo ezivela kwimfuza yabo.

I-Akinesia kunye nedyskinesia: Uyintoni umahluko?

I-Akinesia yahlukile kwi-dyskinesia. I-Dyskinesia inokwenzeka kunye neemeko apho izihlunu zakho ziyagungqa okanye zihambe ngokungathandekiyo. Kwi-akinesia, awukwazi ukuhambisa izihlunu zakho ukuba zihambe (ngamanye amaxesha ngokupheleleyo). Kodwa izihlunu azilahli ubuchule bazo. Yinkqubo ye-extrapyramidal okanye amaziko okuhamba aneziphene.

Kwi-dyskinesia, izihlunu zakho zinokuhamba ngokungalindelekanga okanye rhoqo ngaphandle kokuma. Njenge-akinesia, iDyskinesia inokwenzeka nakwimeko ezinje ngePD.

Iimpawu

Olona phawu lubonakalayo lwe-akinesia “kukubandiswa ngumkhenkce.” Oku kunokukwenza uzive uqinile kwiqela elinye okanye ngaphezulu kwezihlunu. Ingenza ubuso bakho bubukeke ngathi bufriziwe kubuso obunye. Inokukwenza ukuba uhambe kunye nentshukumo eqinileyo engummangaliso eyaziwa ngokuba "kukugodola."

Olu phawu lwenzeka ngenxa yemeko ebizwa ngokuba yi-supranuclear palsy (PSP) eqhubeka ichaphazela ukuhamba kunye nokulinganisela kwangoko kunePD. Ezinye iimpawu ezinokubonakala kunye neakinesia ukuba unePD zibandakanya:

• ukungcangcazela kwezihlunu (ukungcangcazela) ezandleni naseminwe yakho, ngakumbi xa uphumle okanye uphazamisekile
• ukuthambisa kwelizwi okanye intetho ecothayo
• ukungakwazi ukuma nkqo okanye ukugcina ukuma okuthile
• ukuhamba kancinci kwaye kuthatha ixesha elide ukugqiba imisebenzi yomzimba (bradykinesia)

Iimpawu zePSP ezinokubonakala kunye neakinesia (ngakumbi ebusweni) zibandakanya:

• ukungaboni okanye ukungaboni kakuhle
• ukungakwazi ukuhambisa amehlo ngokukhawuleza okukhulu
• ukungakwazi ukujonga phezulu nasezantsi ngokulula
• ukungakwazi ukugcina unxibelelwano ngamehlo ixesha elide
• unengxaki yokuginya
• ukuba neempawu zoxinzelelo, kubandakanya ukutshintsha kwemozulu

Unyango

Amayeza

Olunye lonyango oluqhelekileyo lwe-akinesia njengesiphumo se-PD ngumxube we-levodopa, i-arhente yenkqubo ye-neva, kunye ne-carbidopa. I-Carbidopa inceda ukugcina iziphumo ebezingalindelekanga ze-levodopa, njenge-nausea, ekubeni nzima kakhulu.

I-Akinesia kwi-PD inokwenzeka ngenxa yokunqongophala kwe-dopamine. Ingqondo yakho ivelisa i-dopamine kwaye iyigqithisele emzimbeni wakho zii-neurons. I-Levodopa inceda ukunyanga i-akinesia kunye nezinye iimpawu ze-PD kuba ingqondo yakho iyiguqula ibe yi-dopamine. Inokuhanjiswa emzimbeni wakho ukunceda ekuqiniseni ukuqina kwemisipha ye-akinesia kunye neetics kunye neenyikima zezinye iimpawu zePD.

I-Levodopa kunye ne-carbidopa inokusebenzisana namanye amayeza kwaye ineziphumo ebezingalindelekanga ezibi. Thetha nogqirha wakho malunga nokuba olu nyango lunokukuchaphazela njani ngaphambi kokuba uqale ukuthatha la mayeza.

I-MAO-B inhibitors zikwanceda ukuyeka i-dopamine ekubeni ihlazeke ngokwendalo zii-enzymes zomzimba wakho. Oku kukonyusa inani le-dopamine ekhoyo yokulwa i-akinesia kunye nokucothisa inkqubela phambili ye-PD.

Amayeza aqhele ukusebenza kunyango lwe-akinesia oluvela kwi-PSP. Ukuxinezeleka kunokunceda ukukhulula i-akinesia kunye neempawu zokudakumba ezinokubangelwa yi-PSP. Inaliti ye-botulinum inokunceda ekujonganeni neempawu ezinje ngokuvala ngokunganyanzelekanga kwejwabu leso (i-blepharospasm).

Izikhuthazi ezinokufakwa

Ukuba amayeza asemgangathweni anxibe ngokukhawuleza okanye akanasiphumo sinqwenelekayo kwi-akinesia, oogqirha banokuxoxa ngokubakho kokufakelwa kwee-electrode kukhuthaza amaziko okuhamba. Olu nyango lunceda kwiimpawu kwiimeko eziphambili ngakumbi. Oku kubizwa ngokuba kukukhuthaza okunzulu kwengqondo. Yindlela esetyenziswa ngakumbi nangakumbi kwi-PD.

Kukho izibonelelo kunye nokusikelwa umda. Thetha nogqirha wakho ukuze ubone ukuba bangacebisa olu nyango kuwe.

Ngaphaya kwekhawunta

I-Akinesia inokubangela iintlungu kunye nokuqina, kwaye ukuthatha amayeza e-PD okanye ye-PSP kunokubangela iintlungu kunye nokuphazamiseka. Ukuthomalalisa ukuphelisa iintlungu, njengeziyobisi ezichasayo (ii-NSAID) ezinje nge-ibuprofen kunye ne-acetaminophen kunokunceda ukunciphisa ezinye zeentlungu ezibangelwa yi-PD, i-PSP, okanye amayeza ahambelana nazo.

Olunye unyango kunye nonyango lwasekhaya

Ukufumana umthambo rhoqo kunokukunceda ukunciphisa iintlungu kunye nokuphazamiseka okunokwenzeka nge-akinesia kunye nezinye iimeko zomsebenzi weemoto ezinokubangelwa yi-PD okanye i-PSP. Thetha nogqirha wakho okanye ugqirha ngokwasemzimbeni malunga nokwenza isicwangciso sokuzilolonga esicocekileyo nesikhuselekileyo kuwe ngokuxhomekeke kwiimpawu zakho kunye nokuqhubela phambili kwe-akinesia. Ukuqinisekisa ukuba awuzisebenzisi kakhulu okanye uwa ngexesha lokuzilolonga kubalulekile. Ukwenza i-yoga okanye i-tai chi, enceda ukolula izihlunu zakho, kunokunceda ukucothisa ukuqhubela phambili kwe-akinesia. Ukuzivocavoca kubonisiwe ukulibazisa ukwehla kokusebenza kwi-PD.

Ukuthatha i-coenzyme Q10 kwiinyanga ezininzi kunokukunceda ukuba ukwinqanaba lokuqala lePD okanye iPSP. Ukutya ukutya okuninzi lwefayibha kunye nokusela amanzi amaninzi (ubuncinci ii-ounces ezingama-64 ngosuku) kunokunceda ukugcina iimpawu zakho zincinci.

Unyango olukunceda ukhulule izihlunu zakho, ezinje ngokulambisa kunye nokwenza i-acupuncture, nazo zinokuzikhulula iimpawu zePD kunye nePSP. Ukucamngca okanye ukwenza imisebenzi ekwenza uphumle, njengokumamela umculo okanye ukupeyinta, kunokunceda ukucothisa iziphumo ze-akinesia kunye nokukunceda ugcine ukulawula izihlunu zakho.

Oonobangela kunye nemingcipheko

I-Akinesia ebangelwa yi-PD kunye ne-PSP ayisoloko inesizathu esibonakalayo kuba ezi meko zinokubangelwa kukudityaniswa kwemfuza yakho kunye nokusingqongileyo. Kucingelwa ukuba iziqwengana zethishu kwingqondo yakho ebizwa ngokuba yimizimba yeLeyy inokuba negalelo kwiPD. Iprotein kula mzimba weLeyy, abizwa ngokuba yi-alpha-synuclein, nawo angadlala indima ekwenzeni iPD.

Imbonakalo

I-Akinesia kunye neemeko ezininzi ezibangela ukuba ingekabikho unyango. Kodwa amayeza amaninzi, unyango, kunye notshintsho kwindlela yokuphila zinokukunceda uhlale ukhuthele kwaye ukwazi ukwenza imisebenzi yemihla ngemihla.

Uphando olutsha malunga nePD, i-PSP, kunye nezinye iimeko ezinxulumene noko ziyavela minyaka le, ngakumbi kwimizimba yeLeyy kunye nezinye izinto zebhayiloji ezinokubangela le meko. Olu phando lunokuzisa oogqirha kunye nososayensi kufutshane nokuqonda indlela yokunyanga nokunyanga i-akinesia kunye noonobangela bayo.