Ngaba i-Aspirin inokunceda ekunciphiseni iintlungu zakho ze-Migraine?

Umxholo

• Luthini uphando?
• I-aspirin isebenza njani ekunciphiseni i-migraine?
• Yintoni ekufuneka uyazi malunga nomthamo
• Ngaba i-aspirin ikulungele?
• Ngaba zikhona iziphumo ebezingalindelekanga?
• Iziphumo eziqhelekileyo
• Iziphumo ebezingalindelekanga ezimandundu
• Ukusebenzisana kweziyobisi
• Yintoni enye enokunceda ukukhulula iimpawu ze-migraine?
• Indlela yokuphila kunye nokhetho lwendalo
• Umgca wezantsi

I-Migraine ibangela iintlungu ezinamandla, ezinokubakho ezinokuhlala ukusuka kwiiyure ezimbalwa ukuya kwiintsuku ezininzi. Olu hlaselo lunokuhamba nezinye iimpawu, ezinjengokugabha kunye nokugabha, okanye ukonyusa uvakalelo ekukhanyeni nakwisandi.

I-Aspirin yaziwa njenge-NSAID esetyenziselwa ukunyanga iintlungu ezinqabileyo kunye nokudumba. Iqulethe into esebenzayo acetylsalicylic acid (ASA).

Kule nqaku, siza kujonga ngokuthe ngqo ubungqina beklinikhi malunga nokusetyenziswa kwe-aspirin njengonyango lwe-migraine, umyinge ocetyiswayo, kunye nemiphumo emibi.

Luthini uphando?

Uninzi lophando olukhoyo lubonisa ukuba idosi ephezulu ye-aspirin iyasebenza ekunciphiseni iintlungu kunye nokudumba okunxulunyaniswa ne-migraine.

Ukuphononongwa koncwadi ngo-2013 kuvavanye izifundo ezikumgangatho ophezulu ezili-13 kunye nabathathi-nxaxheba abangama-4,222. Abaphandi baxela ukuba i-1,000-milligram (mg) yedosi ye-aspirin ethathwe ngomlomo yayinakho uku:

• ukubonelela ngoncedo kwi-migraine ngaphakathi kweeyure ezingama-2 ngeepesenti ezingama-52 zabasebenzisi beasprini, xa kuthelekiswa neepesenti ezingama-32 ezithathe i-placebo
• ukunciphisa iintlungu zentloko ukusuka kumodareyitha okanye kubukrakra kungabikho zintlungu kwaphela kwi-1 kwabane abantu abathathe le dose ye-aspirin, xa kuthelekiswa no-1 kwabali-10 abathathe indawo ye-placebo
• ukunciphisa isicaphucaphu ngokukuko xa kudityaniswa ne-anti-nausea drug metoclopramide (Reglan) kunokuba ne-aspirin kuphela

Abaphandi bolu phononongo loncwadi baphinda baxela ukuba i-aspirin iyasebenza njengedosi ephantsi yes sumatriptan, ichiza eliqhelekileyo le-migraine ebukhali, kodwa ayisebenzi njenge-sumatriptan yedosi ephezulu.

Uphononongo loncwadi lwango-2020 luxele iziphumo ezifanayo. Emva kokuhlalutya izilingo ezili-13 ezingenamsebenzi, ababhali bagqiba kwelokuba idosi ephezulu ye-aspirin lunyango olukhuselekileyo nolusebenzayo kwimigraine.

Ababhali baphinde baxela ukuba idosi ephantsi, yemihla ngemihla yeasprini inokuba yindlela efanelekileyo yokuthintela i-migraine engapheliyo. Oku, ewe, kuxhomekeke kwimeko yakho kwaye kuya kufuneka uthethe nogqirha wakho ngaphambi kokuba uqalise naliphi na iyeza lemihla ngemihla.

Oku kufunyenwe kwaxhaswa luphononongo loncwadi lwe-2017 lwezifundo ezisibhozo ezikumgangatho ophezulu. Ababhali baqukumbele ukuba idosi yemihla ngemihla ye-aspirin inokunciphisa ubukhulu bexesha lokuhlaselwa kwemigraine.

Isishwankathelo, ngophando lweklinikhi, iasprini ibonakala isebenza kuzo zombini:

• ukunciphisa intlungu ye-migraine (idosi ephezulu, njengoko kufuneka)
• ukunciphisa i-migraine frequency (ephantsi, idosi yemihla ngemihla)

Ngaphambi kokuba uqale ukuthatha i-aspirin njengenyathelo lokuthintela, qhubeka ufunda ukuze ufumanise ukuba isebenza njani kwaye kutheni oogqirha abaninzi bengayincomi.

I-aspirin isebenza njani ekunciphiseni i-migraine?

Ngelixa singayazi eyona ndlela isebenzayo ekusebenzeni kwe-aspirin kunyango lwe-migraine, ezi zinto zilandelayo zinokunceda:

• Ukuhlaziya. I-Aspirin iyasebenza ekuthomalaliseni iintlungu ezibonisa ukumodareyitha kunye nokudumba. Isebenza ngokuthintela ukuveliswa kweprostaglandin, iikhemikhali ezinje ngehomoni ezidlala indima kwintlungu.
• Ulwaphulo-mthetho. Iprostaglandins ikwan negalelo kukudumba. Ngokuthintela ukuveliswa kweprostaglandin, iasprini ikwajolisa ekuvukeleni, into ebangela ukuhlaselwa yimigraine.

Yintoni ekufuneka uyazi malunga nomthamo

Ugqirha wakho uyakuthathela ingqalelo izinto ezininzi ukumisela ukuba yeyiphi idosi yeasprini ekhuselekileyo ukuba ungayithatha. Ukuba ugqirha wakho ubona ukuba i-aspirin ikhuselekile kuwe, idosi ekucetyiswa ngayo iya kuxhomekeka kubukhali, ubude, kunye nokuhamba rhoqo kweempawu zakho ze-migraine.

Uphando lwamva nje lubonisa la madosi alandelayo emigraine:

• I-900 ukuya kwi-1,300 mg ekuqaleni kohlaselo lwe-migraine
• I-81 ukuya kwi-325 mg ngosuku yokuhlaselwa kwakhona kwe-migraine

Kuya kufuneka uthethe nogqirha wakho malunga nokusetyenziswa kwe-aspirin yokuthintela uhlaselo lwe-migraine. Umbutho weNtloko yeNtloko waseMelika ucebisa ukuba unyango lokuthintela lubekwe kwilingo leenyanga ezi-2 ukuya kwezi-3 ukunqanda ukusetyenziswa gwenxa.

Ukuthatha i-aspirin ngokutya kunokunceda ukunciphisa umngcipheko weziphumo ebezingalindelekanga zesisu.

Ngaba i-aspirin ikulungele?

I-Aspirin ayilunganga kuye wonke umntu. Abantwana abangaphantsi kweminyaka eli-16 akufuneki bathathe iiasprini. I-Aspirin inokuwonyusa umngcipheko womntwana wokufumana isifo sikaReye, isifo esinqabileyo kodwa esibi esibangela ukonakala kwesibindi nengqondo.

I-Aspirin ibeka umngcipheko owongezelelekileyo kubantu abanayo okanye ebebekade benayo:

• ukwaliwa zii-NSAID
• iingxaki zokuvala igazi
• igawuthi
• amaxesha anzima okuya exesheni
• Isibindi okanye isifo sezintso
• izilonda zesisu okanye ukopha emathunjini
• ukopha ngaphakathi kwengqondo okanye elinye ilungu

Yazisa ugqirha wakho ukuba ukhulelwe. I-Aspirin inokusetyenziswa kwiimeko ezizodwa ngexesha lokukhulelwa njengokuphazamiseka kwengqondo. Akukhuthazwa ngaphandle kokuba kukho imeko yonyango engqinelanayo.

Ngaba zikhona iziphumo ebezingalindelekanga?

Njengoninzi lweziyobisi, iasprini iza nomngcipheko weziphumo ebezingalindelekanga ezinokubakho. Oku kunokuba kubumnene okanye kube kubi ngakumbi. Ingakanani i-aspirin oyithathayo kwaye uyithatha kangaphi inokwandisa umngcipheko weziphumo ebezingalindelekanga.

Kubalulekile ukuba uthethe nogqirha wakho malunga nomthamo wakho weasprini ukunciphisa umngcipheko weziphumo ebezingalindelekanga ezinokubakho. Kubalulekile ukuba ungayithathi i-aspirin yonke imihla ngaphandle kokuqala uthethe nogqirha wakho.

Iziphumo eziqhelekileyo

• isisu esimoshakele
• ukuqunjelwa
• isicaphucaphu
• ukopha nokugruzuka ngokulula

Iziphumo ebezingalindelekanga ezimandundu

• isisu esophayo
• ukusilela kwezintso
• ukulimala kwesibindi
• Isifo esibuhlungu
• anaphylaxis, impendulo eyingozi

Ukusebenzisana kweziyobisi

I-Aspirin inokusebenzisana namanye amachiza owathathayo. Kubalulekile ukuba ungayithathi i-aspirin kunye:

• abanye abancinci begazi, njenge-warfarin (Coumadin)
• defibrotide
• dichlorphenamide
• isitofu sokugonya somkhuhlane
• ketorolac (iToradol)

Qiniseka ukuba unika ugqirha wakho uluhlu olupheleleyo lwamayeza amiselweyo kunye nalawo anganyanzelekanga, izongezo zemifuno, kunye neevithamini ozithathayo ukunqanda ukuhlangana okunokwenzeka.

Yintoni enye enokunceda ukukhulula iimpawu ze-migraine?

I-Aspirin yenye yamayeza amaninzi anokunceda ekunciphiseni i-migraine.

Ugqirha wakho uya kuqwalasela izinto ezahlukeneyo-ezinje ngokuba i-migraine inyuka ngokukhawuleza kangakanani kwaye nokuba unazo na ezinye iimpawu-xa usenza isigqibo sokuba ngamayeza afanelekileyo na kuwe.

Amayeza aqhele ukumiselwa kuhlaselo olubi lwe-migraine abandakanya:

• ezinye ii-NSAID, ezinje nge-ibuprofen (Advil, Motrin) okanye naproxen (Aleve, Naprosyn)
• ii-triptan, ezinje nge sumatriptan, zolmitriptan, okanye naratriptan
• I-ergot alkaloids, ezinje nge-dihydroergotamine mesylate okanye i-ergotamine
• Izigantshi
• imisele

Ukuba une-avareji yeentsuku ezine okanye ngaphezulu zokuhlaselwa kwe-migraine ngenyanga, ugqirha wakho unokuyalela amachiza ukunciphisa amaxesha abo.

Amanye amayeza aqhele ukumiselwa ukunceda ukuthintela i-migraine ibandakanya:

• iziyobisi
• ii-anticonvulsants
• amayeza oxinzelelo lwegazi oluphezulu, njenge-ACE inhibitors, i-beta-blockers, okanye i-calcium-block blockers
• I-CGRP inhibitors, iyeza elitsha le-migraine elithintela ukudumba kunye nentlungu
• ityhefu ye-botulinum (Botox)

Indlela yokuphila kunye nokhetho lwendalo

Izinto zokuphila zinokudlala indima kulawulo lwe-migraine. Uxinzelelo, ngakumbi, luhlobo oluqhelekileyo lwe-migraine. Unokwazi ukunciphisa iimpawu ze-migraine ngokusebenzisa iindlela zokulawula uxinzelelo olusempilweni, ezinje:

• iyoga
• ukucamngca
• umthambo wokuphefumla
• ukuphumla kwezihlunu

Ukulala ngokwaneleyo, ukutya ukutya okusempilweni, nokwenza imithambo rhoqo kunokunceda.

Unyango oludibeneyo lwe-migraine abanye abantu abalufumanayo luluncedo lubandakanya:

• biofeedback
• ukutshiza
• izongezo zemifuno

Nangona kunjalo, uphando oluthe kratya luyafuneka ukumisela ukuba ezi zonyango ziyasebenza ekuncedeni ukunciphisa iimpawu ze-migraine.

Umgca wezantsi

I-Triptans, i-ergotamines, i-gepants, i-ditans kunye ne-NSAIDS yonyango lokuqala lokuhlaselwa ngamandla kwe-migraine. Zonke zinobungqina beklinikhi ekusetyenzisweni kwazo.

I-Aspirin yaziwa kakhulu kwi-counter-the-counter NSAID edla ngokusetyenziselwa ukunyanga iintlungu ezinobunzima ukuya kwezingamkelekanga kunye nokudumba.

Uphando luye lwabonisa ukuba xa kuthathwa amanani aphezulu, i-aspirin inokusebenza ekunciphiseni ubuhlungu obukhulu be-migraine. Kuthathwe kwiidosi ezisezantsi rhoqo, i-aspirin inokunceda ukunciphisa i-migraine frequency, kodwa ubude bexesha kufuneka kuxoxwe nogqirha wakho.

Njengoninzi lwamayeza, i-aspirin inokuba neziphumo ebezingalindelekanga kwaye inokungakhuseleki kuwo wonke umntu. Thetha nomboneleli wakho wezempilo ukufumanisa ukuba ngaba iasprini ikhuselekile kuwe njengeyeza lemigraine.