I-Blinatumomab: ye-lymphoblastic leukemia

Umxholo

• Ixabiso
• Yenzelwe ntoni
• Kusetyenziswa kwanjani
• Iziphumo ebezingalindelekanga ezinokwenzeka
• Ngubani ongafanele asebenzise

I-Blinatumomab sisiyobisi esingena ngenaliti esisebenza njenge-antibody, esibophelela kwiimbumba zeseli zomhlaza kunye nokuzivumela ukuba zichongwe ngokulula ngamajoni omzimba. Ke, iiseli zokhuselo zinethuba elilula lokuphelisa iiseli zomhlaza, ngakumbi kwimeko ye-leukemia ebukhali ye-lymphoblastic.

Eli yeza linokwaziwa njengorhwebo njengeBlincyto kwaye kufuneka lisetyenziswe kuphela esibhedlele kunyango lomhlaza, phantsi kolwalathiso lwe-oncologist.

Ixabiso

Eli yeza alinakuthengwa kwiikhemesti eziqhelekileyo, zisetyenziswa kuphela kunyango lomhlaza esibhedlele okanye kumaziko awodwa, njenge-INCA, umzekelo.

Yenzelwe ntoni

I-Blinatumomab ibonakalisiwe kunyango lwe-B-cell ye-lymphoblastic leukemia, i-chromosome engalunganga ye-Philadelphia, ekubuyeni kwakhona okanye kwi-refractory.

Kusetyenziswa kwanjani

Umthamo we-blinatumomab oza kwenziwa kufuneka uhlale ukhokelwa yi-oncologist, njengoko iyahluka ngokweempawu zomntu kunye nenqanaba lesifo.

Unyango lwenziwa ngemijikelo emi-2 yeeveki ezi-4 inye, yahlulwe ngeeveki ezi-2, kwaye kuya kufuneka ulaliswe esibhedlele ngeentsuku ezili-9 zokuqala zomjikelo wokuqala kunye neentsuku ezi-2 zomjikelo wesibini.

Iziphumo ebezingalindelekanga ezinokwenzeka

Iziphumo ebezingalindelekanga eziqhelekileyo zokusebenzisa eliyeza zibandakanya ianemia, ukudinwa kakhulu, uxinzelelo lwegazi, ukuphuthelwa, intloko ebuhlungu, ukungcangcazela, isiyezi, ukukhohlela, isicaphucaphu, ukugabha, ukuqhina, iintlungu esiswini, iintlungu umqolo, umkhuhlane, iintlungu emalungwini, ukugodola kunye utshintsho kuvavanyo lwegazi.

Ngubani ongafanele asebenzise

I-Blinatumomab iyaphikiswa kwabasetyhini abancancisayo kunye nabantu abanezinto ezingezizo kwiyeza ngalinye kwifomula. Ukongeza, kwimeko yabasetyhini abakhulelweyo, kufuneka isetyenziswe kuphela phantsi kokhokelo lwengcali yokubelekisa.