Umhlaza webele

Umxholo

• Isishwankathelo
• Yintoni umhlaza webele?
• Zithini iintlobo zomhlaza wamabele?
• Yintoni ebangela umhlaza webele?
• Ngubani osemngciphekweni womhlaza webele?
• Zithini iimpawu zomhlaza wamabele?
• Ufunyanwa njani umhlaza wamabele?
• Luthini unyango lomhlaza wamabele?
• Ngaba unokuthintelwa umhlaza wamabele?

Isishwankathelo

Yintoni umhlaza webele?

Umhlaza webele ngumhlaza oqala kwinyama yamabele. Kwenzeka xa iiseli ebeleni ziguquka kwaye zikhula ngaphandle kolawulo. Iiseli zihlala zenza ithumba.

Ngamanye amaxesha umhlaza awusasazeki. Oku kubizwa ngokuba "in situ." Ukuba umhlaza usasazeka ngaphandle kwebele, umhlaza ubizwa ngokuba yi "invasive." Inokuthi isasazeka kwizicubu ezikufuphi kunye ne-lymph node. Okanye umhlaza usenokudityaniswa (usasazeke kwamanye amalungu omzimba) ngenkqubo ye-lymph okanye igazi.

Umhlaza wamabele luhlobo lwesibini oluqhelekileyo lomhlaza kwabasetyhini eUnited States. Ngokuqhelekileyo, inokuchaphazela namadoda.

Zithini iintlobo zomhlaza wamabele?

Kukho iintlobo ezahlukeneyo zomhlaza wamabele. Iindidi zisekwe kwiiseli zebele ezijika zibe ngumhlaza. Iindidi zibandakanya

• I-carcinoma yendlela yokuziphatha, oqala kwiiseli zemibhobho. Olu lolona hlobo luqhelekileyo.
• Lobular carcinoma, eqala kwii-lobules. Kuhlala kufumaneka kumabini omabini kunezinye iintlobo zomhlaza wamabele.
• Umhlaza webele odumbisayo, apho iiseli zomhlaza zivimba izitya ze-lymph kulusu lwebele. Isifuba sifudumala, sibomvu, kwaye sidumbile. Olu luhlobo olunqabileyo.
• Isifo sePaget sesifuba, Ngumhlaza obandakanya ulusu lwengono. Ihlala ichaphazela ulusu olumnyama mnyama lujikeleze ingono. Kwakhona kunqabile.

Yintoni ebangela umhlaza webele?

Umhlaza wamabele wenzeka xa kukho utshintsho kwizinto zemvelo (i-DNA). Rhoqo, oyena nobangela wezi nguquko zemfuza awaziwa.

Kodwa ngamanye amaxesha olu tshintsho lwemfuza luthatyathwa njengelifa, oko kuthetha ukuba uzalwa nawo. Umhlaza webele obangelwa lutshintsho lwemfuza olubizwa ngokuba lilifa.

Kukho utshintsho oluthile lwemfuza olunokuphakamisa umngcipheko womhlaza wamabele, kubandakanya utshintsho olubizwa ngokuba yi-BRCA1 kunye ne-BRCA2. Olu tshintsho lubuye luphakamise umngcipheko we-ovari kunye neminye imihlaza.

Ngaphandle kwemfuza, indlela ophila ngayo kunye nokusingqongileyo kunokuchaphazela umngcipheko womhlaza wamabele.

Ngubani osemngciphekweni womhlaza webele?

Izinto eziphakamisa umngcipheko womhlaza wamabele zibandakanya

• Ukwaluphala
• Imbali yomhlaza webele okanye isifo sesifuba (esingaxolisiyo) sesifuba
• Umngcipheko owuzuze njengelifa lomhlaza webele, kubandakanya ukuba ne-BRCA1 kunye ne-BRCA2
• Izicubu zamabele ezixineneyo
• Imbali yokuzala ekhokelela ekuvezweni ngakumbi kwihomoni ye-estrogen, kubandakanya
  • Ukuba sexesheni esemncinci
  • Ukuba semdala xa uqala ukubeleka okanye ungazange wazala
  • Ukuqala ukuya exesheni kamva
• Ukuthatha unyango lwehomoni kwiimpawu zokuyeka ukuya exesheni
• Unyango ngemitha esifubeni okanye esifubeni
• Ukutyeba kakhulu
• Ukusela utywala

Zithini iimpawu zomhlaza wamabele?

Iimpawu kunye neempawu zomhlaza wamabele zibandakanya

• Isigaqa esitsha okanye ukuqina ngaphakathi okanye kufutshane nebele okanye ekhwapheni
• Utshintsho kubukhulu okanye imilo yebele
• Ukuntywila okanye ukuntywila kulusu lwesifuba. Ingakhangeleka ngathi lulusu lweorenji.
• Ingono yajika yangena ebeleni
• Ukukhutshwa kwengono ngaphandle kobisi lwebele. Ukukhutshwa kuya kwenzeka ngesiquphe, kube ligazi, okanye kwenzeke kwisifuba esinye kuphela.
• Isikhumba esibomvu, esibomvu, okanye esidumbileyo kwindawo yengono okanye ebeleni
• Ubuhlungu nakweyiphi na indawo yebele

Ufunyanwa njani umhlaza wamabele?

Umboneleli wakho wezempilo unokusebenzisa izixhobo ezininzi ukufumanisa umhlaza webele kwaye ufumanise ukuba loluphi uhlobo onalo:

• Uvavanyo lomzimba, kubandakanya kuvavanyo lwebele lweklinikhi (i-CBE). Oku kubandakanya ukukhangelwa kwawo nawaphi na amaqhuma okanye nantoni na ebonakala ingaqhelekanga ngamabele nasebusweni.
• Imbali yezonyango
• Ukujonga iimvavanyo, ezinje nge-mammogram, i-ultrasound, okanye iMRI
• Isifuba sebele
• Uvavanyo lwe-chemistry yegazi, olinganisa izinto ezahlukeneyo egazini, kubandakanya ii-electrolyte, amafutha, iiproteni, iswekile (iswekile), kunye nee-enzymes. Ezinye zeemvavanyo ezithile ze-chemistry yegazi zibandakanya iphaneli esisiseko ye-metabolic (BMP), iphaneli ebanzi ye-metabolic (CMP), kunye nephaneli ye-electrolyte.

Ukuba ezi mvavanyo zibonisa ukuba unomdlavuza webele, uya kuba neemvavanyo ezifunda iiseli zomhlaza. Olu vavanyo lunceda umboneleli wakho ukuba athathe isigqibo sokuba loluphi unyango olulungele wena. Iimvavanyo zinokubandakanya

• Uvavanyo lwe-Genetic lotshintsho kwimfuzo olufana ne-BRCA kunye ne-TP53
• Uvavanyo lwe-HER2. I-HER2 yiprotein echaphazelekayo ekukhuleni kweseli. Ingaphandle kwazo zonke iiseli zamabele. Ukuba iiseli zomhlaza wamabele zakho zine-HER2 engaphezulu kwesiqhelo, zinokukhula ngokukhawuleza kwaye zisasazeke kwamanye amalungu omzimba.
• Uvavanyo lwe-estrogen kunye neprogesterone receptor. Olu vavanyo lilinganisa inani le-estrogen kunye neprogesterone (iihormone) receptors kwizicubu zomhlaza. Ukuba kukho ii-receptors ezingaphezulu kwesiqhelo, umhlaza ubizwa ngokuba yi-estrogen kunye / okanye i-progesterone receptor eyakhayo. Olu hlobo lomhlaza webele lunokukhula ngokukhawuleza.

Elinye inyathelo kukubonisa umhlaza. Ukubeka esiteji kubandakanya ukwenza iimvavanyo zokufumanisa ukuba umhlaza usasazekile esifubeni okanye kwamanye amalungu omzimba. Uvavanyo lunokubandakanya ezinye iimvavanyo zokucinga zokuqonda kunye ne-sentinel lymph node biopsy. Le biopsy yenziwa ukubona ukuba umhlaza usasazekile kwii-lymph node.

Luthini unyango lomhlaza wamabele?

Unyango lomhlaza webele lubandakanya

• Utyando olunje
  • Imastectomy, esusa lonke ibele
  • I-lumpectomy yokususa umhlaza kunye nezicubu eziqhelekileyo ezijikelezileyo, kodwa hayi ibele ngokwalo
• Unyango ngemitha
• Unyango ngamayeza
• Unyango lwehormone, ethintela iiseli zomhlaza ekufumaneni iihomoni eziyimfuneko ukuba zikhule
• Unyango ekujoliswe kulo, olusebenzisa iziyobisi okanye ezinye izinto ezihlasela iiseli ezithile zomhlaza ngokungonzakalisi kangako kwiiseli eziqhelekileyo
• Unyango lwe-Immunotherapy

Ngaba unokuthintelwa umhlaza wamabele?

Unokwazi ukunceda ukukhusela umhlaza wamabele ngokwenza utshintsho olusempilweni olufana ne

• Ukuhlala kubunzima obunempilo
• Ukusikela umda ekusebenziseni utywala
• Ukufumana umthambo ngokwaneleyo
• Ukunciphisa ukubonakaliswa kwakho kwi-estrogen nge
  • Ukuncancisa iintsana zakho ukuba unako
  • Ukunciphisa umda kunyango lwehomoni

Ukuba usemngciphekweni omkhulu, umboneleli wakho wezempilo angakucebisa ukuba uthathe amayeza athile ukunciphisa umngcipheko. Abanye abantu basetyhini abasemngciphekweni omkhulu banokugqiba ekubeni bafumane imastectomy (yamabele abo asempilweni) ukuthintela umhlaza wamabele.

Kwakhona kubalulekile ukufumana iimammograms eziqhelekileyo. Banokwazi ukufumanisa umhlaza wamabele kwinqanaba lokuqala, xa kulula ukunyanga.

NIH: IZiko leSizwe loMhlaza

• Umhlaza webele kwi-33: Umgcini weTelemundo Umgcini uAdamari López Ukhokela ngokuhleka
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• UCheryll Plunkett akaze ayeke Ukulwa
• Uvavanyo lweklinikhi lunika isigulana somhlaza wamabele ithuba lesibini
• Ukuchongwa xa ukhulelwe: Ibali loMama Omncinci loMhlaza wamabele
• Ukuphucula iziphumo zabafazi base-Afrika baseMelika abanomhlaza wamabele
• I-NIH yoPhando lweCancer Breast Roundup
• Iinyani ezikhawulezayo kuMhlaza weMastast Breast