I-Decitabine kunye neCedazuridine

Umxholo

• Ngaphambi kokuba uthathe i-decitabine kunye ne-cedazuridine,
• I-Decitabine kunye ne-cedazuridine zinokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

Indibaniselwano ye-decitabine kunye ne-cedazuridine isetyenziselwa ukunyanga iintlobo ezithile ze-myelodysplastic syndrome (iimeko apho umongo wethambo uvelisa iiseli zegazi ezingalunganga kwaye zingavelisi iiseli zegazi ezaneleyo), kubandakanya i-myelomonocytic leukemia (CMML) yabantu abadala. I-Decitabine ikudidi lwamayeza abizwa ngokuba ziiarhente zehypomethylation. Isebenza ngokunceda umongo wethambo uvelise iiseli eziqhelekileyo zegazi kunye nokubulala iiseli ezingaqhelekanga kumongo wethambo. I-Cedazuridine ikwiklasi yamayeza abizwa ngokuba yi-cytidine deaminase inhibitors. Kuyanceda ukonyusa inani le-decitabine emzimbeni ukuze amayeza abe nefuthe elikhulu.

Ukudityaniswa kwe-decitabine kunye ne-cedazuridine kuza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa isisu esingenalutho kwiintsuku ezi-5 zokuqala kumjikelo weentsuku ezingama-28. Musa ukutya ukutya iiyure ezi-2 ngaphambili kunye neeyure ezi-2 emva kwedosi nganye. Inkqubo yomjikelo weentsuku ezingama-28 inokuphindwa njengoko kucetyiswa ngugqirha ngokusekwe ekuphenduleni komzimba wakho kweli yeza. Unyango kufuneka unikezwe ubuncinci imijikelezo emi-4 kodwa inokuqhubeka ukuba ugqirha wakho uthatha isigqibo sokuba uyakuxhamla kunyango olongezelelweyo.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze.

Ukuba uyagabha emva kokuthatha i-decitabine kunye ne-cedazuridine, musa ukuthatha elinye idosi. Qhubeka neshedyuli yakho yesiqhelo.

Ugqirha wakho uya kukunika amayeza okuthintela isicaphucaphu nokugabha ngaphambi kokuba ufumane idosi nganye ye-decitabine kunye ne-cedazuridine.

Ugqirha wakho anganciphisa umthamo wakho okanye ayeke unyango lwakho okwethutyana okanye ngokusisigxina ukuba uneziphumo ebezingalindelekanga ezithile. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho nge-decitabine kunye ne-cedazuridine.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-decitabine kunye ne-cedazuridine,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-decitabine, i-cedazuridine, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-decitabine kunye ne-cedazuridine. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe unesifo sezintso okanye sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa, okanye ukuba ucwangcisa ukuba notata umntwana. Ukuba ungumfazi, kuya kufuneka uthathe uvavanyo lokukhulelwa ngaphambi kokuba uqale unyango kwaye usebenzise ulawulo lokuzalwa ukukhusela ukukhulelwa ngexesha lonyango lwakho kunye neenyanga ezi-6 ubuncinci emva kwethamo lakho lokugqibela. Ukuba uyindoda, wena neqabane lakho labasetyhini kufuneka nisebenzise ulawulo lokuzalwa olusebenzayo ngelixa uthatha i-decitabine kunye ne-cedazuridine kunye neenyanga ezi-3 emva kwedosi yokugqibela. Ukuba wena okanye iqabane lakho ukhulelwa ngelixa uthatha la mayeza, biza ugqirha wakho. I-Decitabine kunye ne-cedazuridine inokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa. Musa ukuncancisa ngelixa uthatha i-decitabine kunye ne-cedazuridine kunye neeveki ezi-2 emva kwedosi yakho yokugqibela.
• Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuzala emadodeni. Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-decitabine kunye ne-cedazuridine.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-decitabine kunye ne-cedazuridine.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba bekungaphantsi kweeyure ezili-12 okoko ubucwangciselwe ukuthatha idosi, thatha idosi ephosiweyo kwisisu esingenanto ngokukhawuleza nje ukuba uyikhumbule. Ukuba sele ngaphezulu kweeyure ezili-12, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yokugcwalisa idosi ezi-5 zemihla ngemihla kumjikelo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Decitabine kunye ne-cedazuridine zinokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukudinwa kakhulu
• ulusu oluthuthu
• ukuqhina
• urhudo
• isicaphucaphu
• ukugabha
• isisu esibuhlungu
• ukuhla ukusinda
• Ukuphelelwa ngumdla wokutya
• intlungu edibeneyo okanye yemisipha
• isiyezi
• iwa phantsi
• intloko ebuhlungu
• ubunzima bokulala okanye ukulala
• izilonda ezibuhlungu emlonyeni, okanye ngolwimi okanye kwimilebe
• ukudumba kwezandla, iinyawo, amaqatha, imilenze esezantsi, okanye isisu
• ukurhawuzelela, ukuba ndindisholo, kunye nentlungu ezandleni nasezinyaweni

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• umkhuhlane, ukugodola, ukukhohlela, iintlungu emzimbeni, okanye ezinye iimpawu zosulelo
• ukopha okungaqhelekanga okanye ukugruzuka, ukopha empumlweni, okanye iintsini ezophayo
• ngokukhawuleza okanye ukubetha kwentliziyo
• ukuqhawukelwa ngumphefumlo
• irhashalala

I-Decitabine kunye ne-cedazuridine zinokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ngaphambi nangexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwi-decitabine nakwi-cedazuridine.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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