Ioyile ye-CBD yeMigraine: Ngaba iyasebenza?

Umxholo

• Uthini uphando nge-CBD
• Isifundo nge-CBD kunye ne-THC
• Olunye uphando lwe-cannabis
• Izifundo malunga nentsangu yezonyango
• Funda ku-nabilone
• Isebenza njani i-CBD
• Uyisebenzisa kanjani i-CBD
• Iziphumo ezinobungozi kunye neengozi
• Ngaba i-CBD iya kukuphakamisa?
• Ukuba semthethweni
• Thetha nogqirha wakho
• I-3 ye-Yoga inokuthi ikhuphe iMigraines

Ushwankathelo

Uhlaselo lwe-Migraine ludlula ngaphaya koxinzelelo oluqhelekileyo- okanye iintlungu ezinxulumene nonyango. Ukuhlaselwa kweMigraine kuhlala naphi na ukusuka kwiiyure ezi-4 ukuya kwezingama-72. Nokuba ezona zinto zixhaphakileyo, ezinje ngokuhamba okanye ukujikeleza ingxolo kunye nokukhanya, zinokuzandisa iimpawu zakho.

Ngelixa amayeza eentlungu anokunceda okwethutyana ukunciphisa iimpawu zokuhlaselwa yimigraine, unokukhathazeka ngemiphumo yazo. Kulapho i-cannabidiol (i-CBD) inokungena khona.

I-CBD yenye yezinto ezininzi ezisebenzayo ezifumaneka kwisityalo se-cannabis. Ikhulile ekuthandeni njengendlela yokunyanga ngokwendalo iimeko ezithile zonyango.

Qhubeka ufunda ukuze ufumane:

• uthini uphando lwangoku malunga nokusebenzisa i-CBD kwimigraine
• Ingaba isebenza kanjani
• iziphumo ebezingalindelekanga ezinokubakho kunye nokunye

Uthini uphando nge-CBD

Uphando ngokusetyenziswa kwe-CBD kwimigraine lilinganiselwe. Izifundo ezikhoyo zijonga iziphumo ezidibeneyo ze-CBD kunye ne-tetrahydrocannabinol (THC), i-cannabinoid eyahlukileyo. Okwangoku akukho zifundo zipapashiweyo zivavanya iziphumo ze-CBD njengesithako esinye kwimigraine.

Olu phando lilinganiselweyo lubangelwa, ngokuyinxenye, kwimigaqo kwi-CBD kunye nezithintelo ezisemthethweni zokumisela i-cannabis. Okwangoku, ezinye izifundo zelebhu zicebise ukuba ioyile ye-CBD inokunceda zonke iintlobo zentlungu engapheliyo kunye neentlungu, kubandakanya ne-migraine.

Isifundo nge-CBD kunye ne-THC

Kwi-2017, kwi-3rd Congress ye-European Academy ye-Neurology (i-EAN), iqela labaphandi labonisa iziphumo zophando lwabo kwii-cannabinoids kunye nothintelo lwe-migraine.

Kwinqanaba I lokufunda kwabo, abantu be-48 abane-migraine engapheliyo bafumana indibaniselwano yeekhompawundi ezimbini. Ikhompawundi inezinye iipesenti ezili-19 ze-THC, ngelixa enye yayiqulathe iipesenti ezili-9 ze-CBD kwaye akukho-THC. Iikhompawundi zazilawulwa ngomlomo.

Iidosi ezingaphantsi kwe-100 milligrams (mg) khange zibe nasiphumo. Xa iidosi zonyuswe zaya kwi-200 mg, iintlungu eziqatha zancitshiswa ngama-55 eepesenti.

Isigaba II sesifundo sijonge abantu abane-migraine engapheliyo okanye iintloko zentloko. Abantu abangama-79 abane-migraine engapheliyo bafumana idosi yemihla ngemihla ye-200 mg ye-THC-CBD yokudibanisa ukusuka kwisigaba I okanye i-25 mg ye-amitriptyline, i-tricyclic antidepressant.

Abantu abangama-48 abaneentloko ezisebenzisanayo bafumana idosi yemihla ngemihla ye-200 mg ye-THC-CBD indibaniselwano ukusuka kwisigaba I okanye i-480 mg ye-verapamil, i-calcium channel blocker.

Ixesha lokunyanga lahlala iinyanga ezintathu, kwaye ukulandelelwa kwenzeka kwiiveki ezine emva kokuba unyango luphelile.

Umdibaniso we-THC-CBD unciphise ukuhlaselwa kwe-migraine ngama-40.4 epesenti, ngelixa i-amitriptyline ikhokelele ekunciphiseni iipesenti ezingama-40.1 kuhlaselo lwe-migraine. Indibaniselwano ye-THC-CBD ikwanciphisile ubunzima beentlungu ngeepesenti ezingama-43.5.

Abathathi-nxaxheba abaneentloko ezisebenzisanayo babone ukwehla kancinci kubukhali kunye nokuhamba rhoqo kweentloko zabo.

Nangona kunjalo, abanye babone ukuba iintlungu zabo ziyehla ngeepesenti ezingama-43.5. Oku kwehla kobunzima beentlungu kwajongwa kuphela kubathathi-nxaxheba ababenokuthi bahlaselwe yimigraine eqala ebuntwaneni.

Abaphandi bagqiba kwelokuba ii-cannabinoids zazisebenza kuphela ngokuchasene neentloko zeentloko ezomeleleyo ukuba umntu ebehlaselwe yimigraine njengomntwana.

Olunye uphando lwe-cannabis

Uphando ngezinye iintlobo ze-cannabis lunokunika ithemba elongezelelweyo kulabo abafuna ukukhululeka kwintlungu ye-migraine.

Izifundo malunga nentsangu yezonyango

Ngo-2016, i-Pharmacotherapy yashicilela isifundo malunga nokusetyenziswa kwentsangu yonyango kwimigraine. Abaphandi bafumanisa ukuba kubantu abangama-48 abaphononongiweyo, iipesenti ezingama-39.7 zichaze ukuhlaselwa kwe-migraine okumbalwa.

Ukozela yayisesona sikhalazo sikhulu, ngelixa abanye babenzima ekufumaneni idosi elungileyo. Abantu abasebenzisa intsangu enokutyiwa, ngokuchaseneyo nokuyifaka ngaphakathi okanye ukusebenzisa ezinye iifom, bafumana iziphumo ebezingalindelekanga.

Isifundo se-2018 sijonge abantu abangama-2,032 abane-migraine, intloko ebuhlungu, isifo samathambo, okanye iintlungu ezingapheliyo njengophawu lokuqala okanye ukugula. Uninzi lwabathathi-nxaxheba lukwazile ukutshintsha amayeza amiselweyo-ngesiqhelo ii-opioids okanye ii-opiates- nge-cannabis.

Onke amaqela amancinci akhetha iintlobo ze-hybridi ze-cannabis. Abantu abakwi-migraine kunye neentloko zentloko bakhetha i-OG Shark, uhlobo lwe-hybrid olunamanqanaba aphezulu e-THC kunye namanqanaba asezantsi e-CBD.

Funda ku-nabilone

Isifundo se-2012 sase-Italiya sivavanye iziphumo ze-nabilone, uhlobo lwento ye-THC, kwizifo zentloko. Abantu abangamashumi amabini anesithandathu abanamava okusebenzisa kakhulu iintloko baqala ngokuthatha idosi yomlomo nokuba yeyiphi .50 mg ngosuku lwe-nabilone okanye i-400 mg ngosuku lwe-ibuprofen.

Emva kokuthatha iyeza elinye iiveki ezisibhozo, abathathi-nxaxheba bahamba ngaphandle kweyeza iveki enye. Emva koko batshintshela kwelinye iyeza kwiiveki ezisibhozo zokugqibela.

Omabini la machiza abonakalise ukuba ayasebenza. Nangona kunjalo, ekupheleni kwesifundo, abathathi-nxaxheba baxele ukuphucuka okungakumbi kunye nomgangatho wobomi obungcono xa bethatha i-nabilone.

Sebenzisa i-nabilone kukhokelele kwintlungu engathethekiyo kunye nokuhla kweziyobisi. Akukho nasinye isiyobisi esinefuthe elibonakalayo kuhlaselo lwe-migraine, abathi abaphandi babanga ixesha elifutshane lofundo.

Isebenza njani i-CBD

I-CBD isebenza ngokudibana ne-receptors yomzimba ye-cannabinoid (CB1 kunye ne-CB2). Nangona iindlela zingaqondakali ngokupheleleyo, ii-receptors zinokuchaphazela amajoni omzimba.

Umzekelo, i-CBD inokuthi. Ikhompawundi i-anandamide inxulunyaniswa nolawulo lwentlungu. Ukugcina amanqanaba aphezulu e-anandamide egazini lakho kunokunciphisa iimvakalelo zakho zentlungu.

I-CBD ikwacingelwa ukuba iyakuthintela ukudumba emzimbeni, okunokunceda ukunciphisa iintlungu kunye nezinye iimpendulo zomzimba.

Uphando olungakumbi luyafuneka ukuqonda ngakumbi ukuba i-CBD inokuwuchaphazela njani umzimba.

Uyisebenzisa kanjani i-CBD

Nangona abenzi bomthetho eUnited States kungoku nje bexoxa ngokufaneleka kwentsangu kunye neemveliso ezinxulumene noko, ukusetyenziswa kwesityalo njengamayeza asikokufumanisa kutsha.

Ngokwe-cannabis, sele isetyenziswe kwamanye amayeza ngaphezulu kweminyaka engama-3 000. Ezinye zezi zinto zibandakanya ulawulo lwe:

• intlungu
• iimpawu ze-neurological
• ukudumba

Ioyile ye-CBD inokuba:

• umphunga
• ukungenisa
• ifakwe kumxholo

I-CBD yomlomo ayinakufane ibangele iziphumo ebezingalindelekanga kune-vaping, ke abanye babaqalayo banokufuna ukuqala apho. Unga:

• beka iithontsi ezimbalwa zeoli phantsi kolwimi lwakho
• thatha iicapsule ze-CBD
• yitya okanye usele inyango efakwe yi-CBD

I-oyile ye-Vaping ye-CBD inokuba luncedo ukuba ufumana i-migraine eqatha ekhaya kwaye akufuneki ushiye uye kwenye indawo.

Ichaza ukuba inkqubo yokuphefumla ihambisa iikhompawundi kwigazi lakho ngokukhawuleza ngakumbi kunezinye iindlela.

Okwangoku, azikho izikhokelo ezisemthethweni zedosi efanelekileyo yokuhlaselwa migraine. Sebenza nogqirha wakho ukumisela idosi efanelekileyo.

Ukuba umtsha kwioyile ye-CBD, kuya kufuneka uqale ngeyona dosi incinci kunokwenzeka. Ungayisebenza kancinci kancinci indlela yakho ukuya kuthi ga kwidosi epheleleyo ecetyiswayo. Oku kuyakuvumela umzimba wakho ukuba uqhelane neoyile kunye nokunciphisa umngcipheko weziphumo ebezingalindelekanga.

Iziphumo ezinobungozi kunye neengozi

Ngokubanzi, izifundo zibonisa ukuba iziphumo ebezingalindelekanga ze-CBD kunye neoyile ye-CBD zincinci. Esi sesinye sezizathu eziphambili zokuba kutheni abantu bekhetha ukuphuma kwikhawuntari (i-OTC) okanye amayeza amayeza eentlungu.

Ewe kunjalo, ukudinwa, ukozela, kunye nesisu esibuhlungu kunokwenzeka, kunye notshintsho kumdla wokutya kunye nobunzima. Ityhefu yesibindi ikwabonakalisiwe kwiimpuku eziye zanyanzeliswa ngeedosi ezinkulu kakhulu ze-CBD ezityebileyo ze-cannabis.

Umngcipheko weziphumo ebezingalindelekanga unokuxhomekeka kwindlela oyisebenzisa ngayo ioyile ye-CBD. Umzekelo, ukuphuma kunokubangela ukuphazamiseka kwemiphunga. Oku kungakhokelela ku:

• ukukhwehlela okungapheliyo
• ukuvutha
• ubunzima bokuphefumla

Ukuba une-asthma okanye olunye uhlobo lwesifo semiphunga, ugqirha wakho unokucebisa ngokuchasene neoyile ye-CBD.

Ukuba awuqinisekanga malunga neziphumo ebezingalindelekanga ezinokubakho okanye indlela umzimba wakho onokuzisingatha ngayo, thetha nogqirha wakho.

Ukuba uthatha namanye amayeza okanye izongezo zokutya, khumbula ukudibana kweziyobisi. I-CBD inokusebenzisana neziyobisi ezahlukeneyo, kubandakanya:

• iyeza lokubulala iintsholongwane
• iziyobisi
• abacoci gazi

Lumka ngakumbi ukuba uthatha iyeza okanye isongezelelo esidibana ne-grapefruit. I-CBD kunye ne-grapefruit zombini ziyasebenzisana nee-enzyme- ezinje ngecytochromes P450 (CYPs) -izinto ezibalulekileyo kwimetabolism yeziyobisi.

Ngaba i-CBD iya kukuphakamisa?

Iioyile ze-CBD zenziwe nge-cannabis, kodwa azisoloko ziqulathe i-THC. I-THC yi-cannabinoid eyenza ukuba abasebenzisi bazive "bephezulu" okanye "bexulutywa ngamatye" xa betshaya i-cannabis.

Zimbini iintlobo zeentlobo ze-CBD ezikhoyo kwintengiso:

• ephezulu
• sisityebi

Uhlobo lwe-CBD olulawulayo alunanto kwi-THC, ngelixa ubunzima be-CBD buqulethe ii-cannabinoids.

I-CBD ngaphandle kwe-THC ayinazipropathi zengqondo.Nokuba ukhetha imveliso edibeneyo, i-CBD ihlala ichasene nefuthe le-THC, ngokweProjekthi ye-CBD engenzi nzuzo. Esi sesinye sezizathu zokuba ukhethe ioyile ye-CBD ngaphezulu kwentsangu yonyango.

Ngaba i-CBD isemthethweni? Iimveliso ze-CBD ezenziwe ngentsangu azikho semthethweni kwinqanaba lomanyano, kodwa zisemthethweni phantsi kwemithetho ethile karhulumente. Iimveliso ze-CBD ezenziwe ngeHemp (ezingaphantsi kweepesenti ze-0,3 ze-THC) zisemthethweni kwinqanaba lomdibaniso, kodwa azikho semthethweni phantsi kweminye imithetho yelizwe. Jonga imithetho yelizwe lakho kunye nayo nayiphi na indawo ohamba kuyo. Gcina ukhumbula ukuba iimveliso ze-CBD ezingabhaliswanga azivunyelwanga yi-FDA, kwaye zinokubhalwa ngokungachanekanga.

Ukuba semthethweni

Ngenxa yezinto zengqondo zentsangu yendabuko, i-cannabis ihlala ikhutshiwe kwezinye iindawo zase-United States.

Nangona kunjalo, inani elikhulayo lamazwe livotele ukuvuma i-cannabis yokusetyenziswa kwezonyango kuphela. Abanye babhalise i-cannabis ngokusemthethweni nasetyenziselwa amayeza kunye nokuzonwabisa.

Ukuba uhlala kwimeko apho intsangu isemthethweni kunyango nakwezokuzonwabisa, kufuneka ube nokufikelela kwioyile ye-CBD, nayo.

Nangona kunjalo, ukuba ilizwe lakho lisemthethweni i-cannabis yokusebenzisa amayeza kuphela, kuya kufuneka ufake isicelo semakhadi yentsangu kugqirha wakho ngaphambi kokuthenga iimveliso ze-CBD. Eli phepha-mvume liyafuneka ekusetyenzisweni kwazo zonke iintlobo zentsangu, kubandakanya ne-CBD.

Kwamanye amazwe, zonke iintlobo zentsangu azikho semthethweni. Ngokudibeneyo, i-cannabis isahlelwa njengeziyobisi eziyingozi nezingekho mthethweni.

Kubalulekile ukuba uqaphele imithetho ekwilizwe lakho nakwamanye amazwe onokuthi uwatyelele. Ukuba iimveliso ezinxulumene ne-cannabis azikho mthethweni-okanye ukuba zifuna ilayisensi yezonyango ongenayo-unokufumana isohlwayo sokubamba.

Thetha nogqirha wakho

Uphando oluthe kratya luyafuneka ngaphambi kokuba ioyile ye-CBD ibe yindlela yokonyango yesiqhelo ye-migraine, kodwa kufanelekile ukuba uthethe nogqirha wakho ukuba unomdla. Banokukucebisa ngedosi efanelekileyo kunye nazo naziphi na iimfuno zomthetho.

Ukuba uthatha isigqibo sokuzama ioyile ye-CBD, yiphathe ngokungathi unokwenza nolunye unyango kunyango lwe-migraine. Kungathatha ixesha elithile ukuba usebenze, kwaye kuya kufuneka uhlengahlengise idosi yakho ukuze ilungele iimfuno zakho.

I-3 ye-Yoga inokuthi ikhuphe iMigraines