Uvavanyo lwe-CCP Antibody

Umxholo

• Luthini uvavanyo lweCCP?
• Isetyenziselwa ntoni?
• Kutheni ndifuna uvavanyo lwe-CCP antibody?
• Kwenzeka ntoni ngexesha lovavanyo lomzimba omzimba lweCCP?
• Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?
• Ngaba bukhona ubungozi kuvavanyo?
• Zithetha ntoni iziphumo?
• Ngaba ikhona enye into endifuna ukuyazi malunga novavanyo lomzimba lweCCP?
• Izalathiso

Luthini uvavanyo lweCCP?

Olu vavanyo lujonga i-CCP (cyclic citrullinated peptide) antibodies egazini. Iintsholongwane zeCCP, ezibizwa ngokuba ngama-anti-CCP antibodies, ziluhlobo lomzimba olubizwa ngokuba zii-autoantibodies. Ama-antibodies kunye nee-autoantibodies ziiproteni ezenziwe ngamajoni omzimba. Iintsholongwane zikukhusela kwizifo ngokulwa nezinto zangaphandle ezinjengeentsholongwane kunye neentsholongwane. Ii-autoantibodies zinokubangela isifo ngokuhlasela iiseli zomzimba ezisempilweni ngempazamo.

Iintsholongwane zeCCP zijolise kwizicubu ezisempilweni kumalungu. Ukuba ngaba ii-antibodies zeCCP zifunyenwe egazini lakho, inokuba luphawu lwe-rheumatoid arthritis. I-rheumatoid arthritis sisifo esiqhubela phambili, esizenzekelayo esenza iintlungu, ukudumba, kunye nokuqina kwamalungu. Iintsholongwane zeCCP zifumaneka ngaphezu kweepesenti ezingama-75 zabantu abane-rheumatoid arthritis. Phantse azange zifunyanwe kubantu abangenaso isifo.

Amanye amagama: i-cyclic citrullinated peptide antibody, i-peptide antibody engavumelekanga

Isetyenziselwa ntoni?

Uvavanyo lwe-CCP antibody lusetyenziselwa ukunceda ukufumanisa isifo samathambo. Ihlala isenziwa kunye okanye emva kovavanyo lwe-rheumatoid factor (RF). Iimpawu zerheumatoid lolunye uhlobo lwe-autoantibody. Iimvavanyo ze-RF zisetyenziselwa ukuba luvavanyo oluphambili lokunceda ukufumanisa isifo samathambo. Kodwa izinto ze-RF zinokufumaneka kubantu abanezinye izifo ezizimeleyo kunye nakwabanye abantu abaphilileyo. Izifundo ezininzi zibonise ukuba ii-antibodies zeCCP zibonelela ngokuchanekileyo ngokuchaneka kwesifo samathambo xa kuthelekiswa novavanyo lweRF.

Kutheni ndifuna uvavanyo lwe-CCP antibody?

Unokulufuna olu vavanyo ukuba uneempawu zesifo samathambo. Oku kubandakanya:

• Intlungu edibeneyo
• Ukuqina ngokudibeneyo, ngakumbi kusasa
• Ukudumba ngokudibeneyo
• Ukudinwa
• Umkhuhlane ophantsi

Unokulufuna olu vavanyo ukuba ezinye iimvavanyo azinakuqinisekisa okanye zithintele ukuxilongwa kwesifo samathambo.

Kwenzeka ntoni ngexesha lovavanyo lomzimba omzimba lweCCP?

Ingcali yokhathalelo lwempilo iyakuthatha isampulu yegazi kumthambo engalweni yakho, isebenzisa inaliti encinci. Emva kokuba inaliti ifakiwe, inani elincinci legazi liya kuqokelelwa kwityhubhu yovavanyo okanye igutyana. Unokuziva uluma kancinci xa inaliti ingena okanye iphuma. Oku kuhlala kuthatha imizuzu engaphantsi kwesihlanu.

Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?

Qiniseka ukuba uxelela umboneleli wakho wezempilo malunga nawo onke amayeza, iivithamini, kunye nezongezo zokutya ozithathayo. Kuya kufuneka uyeke ukuthatha izinto ezithile iiyure ezisi-8 ngaphambi kovavanyo lwakho.

Ngaba bukhona ubungozi kuvavanyo?

Mncinci kakhulu umngcipheko wokuvavanywa kwegazi. Unokuba nentlungu encinci okanye ukrakra kwindawo apho inaliti yafakwa khona, kodwa uninzi lweempawu zihamba ngokukhawuleza.

Zithetha ntoni iziphumo?

Ukuba iziphumo zomzimba wakho ze-CCP bezikho, oko kuthetha ukuba ezi ntsholongwane zifunyenwe egazini lakho. Iziphumo ezingalunganga zithetha ukuba akukho zintsholongwane zeCCP zifunyenweyo. Intsingiselo yezi ziphumo inokuxhomekeka kwiziphumo zovavanyo lwe-rheumatoid factor (RF) kunye novavanyo lomzimba.

Ukuba unempawu zesifo samathambo, kwaye iziphumo zakho zibonisa:

• Iintsholongwane ze-CCP ezifanelekileyo kunye ne-RF elungileyo, kusenokwenzeka ukuba kuthetha ukuba unesifo samathambo.
• Amajoni omzimba aqinisekileyo e-CCP kunye ne-RF engathandekiyo, oko kunokuthetha ukuba ukwinqanaba lokuqala lesifo samathambo okanye uza kuyiphuhlisa kwixa elizayo.
• Iintsholongwane ze-CCP ezingezizo kunye ne-RF engathandekiyo, oko kuthetha ukuba akunakufane ube nesifo samathambo. Umboneleli wakho unokufuna ukwenza iimvavanyo ezingaphezulu ukunceda ukufumanisa ukuba yintoni ebangela iimpawu zakho.

Funda ngakumbi malunga novavanyo lwelabhoratri, uluhlu lweereferensi, kunye neziphumo zokuqonda.

Ngaba ikhona enye into endifuna ukuyazi malunga novavanyo lomzimba lweCCP?

I-rheumatoid arthritis kunokuba nzima ukuyichonga, ngakumbi kumanqanaba ayo okuqala. Umboneleli wakho unoku-odola uvavanyo olunye okanye nangaphezulu ukongeza kwi-CCP antibody kunye ne-RF. Oku kubandakanya ii-ray-ray zamalungu akho kunye novavanyo lwegazi olulandelayo:

• Izinga le-sedimentation ye-Erythrocyte (ESR)
• Uhlalutyo lwamanzi eSynovial
• Iprotheyini esebenzayo yeC
• Intshatsheli yomzimba

Olu vavanyo lwegazi lunokubonisa iimpawu zokudumba. Ukuvuvukala luhlobo lokuphendula kwamajoni omzimba. Ingaba luphawu lwe-rheumatoid arthritis.

Izalathiso

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Ulwazi olukule ndawo akufuneki lusetyenziswe endaweni yonyango okanye iingcebiso. Nxibelelana nomboneleli wezempilo ukuba unemibuzo malunga nempilo yakho.