Uvavanyo lweCeruloplasmin

Umxholo

• Yintoni uvavanyo lweCeruloplasmin?
• Isetyenziselwa ntoni?
• Kutheni ndifuna uvavanyo lweCeruloplasmin?
• Kwenzeka ntoni ngexesha lovavanyo lweceruloplasmin?
• Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?
• Ngaba bukhona ubungozi kuvavanyo?
• Zithetha ntoni iziphumo?
• Ngaba ikhona enye into endifuna ukuyazi malunga novavanyo lweceruloplasmin?
• Izalathiso

Yintoni uvavanyo lweCeruloplasmin?

Olu vavanyo lilinganisa inani le-ceruloplasmin egazini lakho. I-Ceruloplasmin yiprotein eyenziwe kwisibindi. Igcina kwaye ithwale ubhedu ukusuka esibindini iye egazini kunye nakumalungu omzimba wakho ayifunayo.

I-Copper yiminerali efumaneka kukutya okuninzi, kubandakanya amandongomane, itshokholethi, amakhowa, iqokobhe kunye nesibindi. Kubalulekile kwimisebenzi emininzi yomzimba, kubandakanya ukwakha amathambo omeleleyo, ukuvelisa amandla, kunye nokwenza i-melanin (into enika ulusu umbala wayo). Kodwa ukuba unobhedu oluninzi okanye oluncinci egazini lakho, inokuba luphawu lwengxaki enkulu yezempilo.

Amanye amagama: CP, ceruloplasmin uvavanyo lwegazi, ceruloplasmin, serum

Isetyenziselwa ntoni?

Uvavanyo lwe-ceruloplasmin luhlala lusetyenziswa, kunye novavanyo lobhedu, ukunceda ukufumanisa isifo seWilson. Isifo sikaWilson sisifo esingaqhelekanga semfuza esithintela umzimba ekususeni ubhedu obuninzi. Inokubangela ukwakheka okuyingozi kobhedu esibindini, kwingqondo nakwamanye amalungu.

Ingasetyenziselwa ukuxilonga iingxaki ezibangela ukungabikho kobhedu (ubuncinci obuncinci). Oku kubandakanya:

• Ukungondleki, imeko apho ungafumani zondlo zaneleyo ekudleni kwakho
• I-Malabsorption, imeko eyenza ukuba kubenzima emzimbeni wakho ukufunxa kwaye usebenzise izakhamzimba ozityayo
• Isifo seMenkes, isifo esinqabileyo, esinganyangekiyo semfuza

Ukongeza, uvavanyo ngamanye amaxesha lusetyenziselwa ukufumanisa isifo sesibindi.

Kutheni ndifuna uvavanyo lweCeruloplasmin?

Umboneleli wakho wezempilo unokuyalela uvavanyo lwe-ceruloplasmin ukuba uneempawu zesifo sikaWilson. Oku kubandakanya:

• Ukunqongophala kwegazi
• IJaundice (tyheli kolusu namehlo)
• Isicaphucaphu
• Intlungu zesisu
• Ingxaki yokuginya kunye / okanye ukuthetha
• Iinyikima
• Unengxaki yokuhamba
• Utshintsho kwindlela yokuziphatha

Unokulufuna olu vavanyo ukuba unembali yosapho yesifo seWilson, nokuba awunampawu. Iimpawu zihlala zivela phakathi kweminyaka emi-5 ukuya kwengama-35, kodwa zinokubonisa kwangoko okanye kamva ebomini.

Unako ukufumana olu vavanyo ukuba unempawu zokusilela kobhedu (ubhedu oluncinci kakhulu). Oku kubandakanya:

• Ulusu oluthuthu
• Amanqanaba asezantsi ngokungaqhelekanga iiseli ezimhlophe zegazi
• I-Osteoporosis, imeko ebangela ukuba buthathaka kwamathambo kwaye ibenze bathambekele ekuqhekekeni
• Ukudinwa
• Ukulinganisa izandla neenyawo

Umntwana wakho unokufuna olu vavanyo ukuba uneempawu zesifo seMenkes. Iimpawu zihlala zibonisa ebusaneni kwaye zibandakanya:

• Iinwele ezi brittle, sparse, kunye / okanye ezixineneyo
• Ubunzima bokutya
• Ukusilela ukukhula
• Ukulibaziseka kophuhliso
• Ukungabikho kwethoni yezihlunu
• Ukuxhuzula

Uninzi lwabantwana abanesi sifo bafa kwiminyaka embalwa yokuqala yobomi, kodwa unyango lwakwangoko lunokunceda abanye abantwana baphile ixesha elide.

Kwenzeka ntoni ngexesha lovavanyo lweceruloplasmin?

Ingcali yokhathalelo lwempilo iyakuthatha isampulu yegazi kumthambo engalweni yakho, isebenzisa inaliti encinci. Emva kokuba inaliti ifakiwe, inani elincinci legazi liya kuqokelelwa kwityhubhu yovavanyo okanye igutyana. Unokuziva uluma kancinci xa inaliti ingena okanye iphuma. Oku kuhlala kuthatha imizuzu engaphantsi kwesihlanu.

Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?

Awudingi naluphi na ulungiselelo olukhethekileyo lovavanyo lwe-ceruloplasmin.

Ngaba bukhona ubungozi kuvavanyo?

Mncinci kakhulu umngcipheko wokuvavanywa kwegazi. Unokuba nentlungu encinci okanye ukrakra kwindawo apho inaliti yafakwa khona, kodwa uninzi lweempawu zihamba ngokukhawuleza.

Zithetha ntoni iziphumo?

Inqanaba elingaphantsi kweqhelekileyo le-ceruloplasmin linokuthetha ukuba umzimba wakho awukwazi ukusebenzisa okanye ukuphelisa ubhedu ngokufanelekileyo. Inokuba luphawu loku:

• Isifo sikaWilson
• Isifo seMenkes
• Isifo sesibindi
• Ukungondleki
• Malabsorption
• Isifo sezintso

Ukuba amanqanaba akho e-ceruloplasmin ayephezulu kunesiqhelo, kunokuba luphawu loku:

• Usulelo olubi
• Isifo sentliziyo
• Irheumatoid Arthritis
• Ileukemia
• IHodgkin lymphoma

Kodwa amanqanaba aphezulu e-ceruloplasmin anokubakho ngenxa yeemeko ezingadingi nyango. Oku kubandakanya ukukhulelwa kunye nokusetyenziswa kweepilisi zolawulo lokuzalwa.

Ukuba unemibuzo malunga neziphumo zakho, thetha nomboneleli wakho wezempilo.

Funda ngakumbi malunga novavanyo lwelabhoratri, uluhlu lweereferensi, kunye neziphumo zokuqonda.

Ngaba ikhona enye into endifuna ukuyazi malunga novavanyo lweceruloplasmin?

Iimvavanyo zeCeruloplasmin zihlala zenziwa kunye nolunye uvavanyo. Oku kubandakanya uvavanyo lobhedu egazini kunye / okanye kumchamo nakwiimvavanyo zomsebenzi wesibindi.

Izalathiso

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2. Iklinikhi yaseCleveland [kwi-Intanethi]. Cleveland (OH): Iiklinikhi yaseCleveland; c2019. Isifo sikaWilson: Ubume [icatshulwe ngo-2019 ngoJulayi 18]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://my.clevelandclinic.org/health/diseases/5957-wilson-disease
3. UHinkle J, uCheever K. Brunner kunye neSuddarth's Handbook yeLebhu kunye noVavanyo lokuChonga. 2nd Ed, Kindle. IPhiladelphia: Impilo yeWolters Kluwer, uLippincott Williams kunye noWilkins; Ngowama-2014. Iceruloplasmin; iphe. 146.
4. IKaler SG, Holmes CS, Goldstein DS, Tang J, Godwin SC, Donsante A, Liew CJ, Sato S, Patronas N. Neonatal diagnostic kunye nonyango lwezifo zeMenkes. N Engl J Med [Intanethi]. 2008 Feb 7 [icatshulwe ngo-2019 ngoJulayi 18]; 358 (6): 605–14. Ifumaneka kwi: https://www.ncbi.nlm.nih.gov/pubmed/18256395
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10. I-NIH yeLayibrari yeSizwe yoNyango yezeMpilo: Isalathiso seKhaya leMfuza [kwi-Intanethi]. I-Bethesda (MD): Isebe lezeMpilo laseMelika kunye neeNkonzo zoLuntu; Isifo seMenkes; 2019 Jul 16 [icatshulwe ngo-2019 ngoJulayi 18]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://ghr.nlm.nih.gov/condition/menkes-syndrome#ingcaciso
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Ulwazi olukule ndawo akufuneki lusetyenziswe endaweni yonyango okanye iingcebiso. Nxibelelana nomboneleli wezempilo ukuba unemibuzo malunga nempilo yakho.