Umbhali: Randy Alexander
Umhla Wokudalwa: 26 Utshazimpuzi 2021
Hlaziya Umhla: 24 Isilimela 2024
Anonim
Impendulo edibeneyo (ipratropium / albuterol) - Enye
Impendulo edibeneyo (ipratropium / albuterol) - Enye

Umxholo

Yintoni iMpendulo edibeneyo?

Impendulo edibeneyo ligama lonyango elinegama lophawu. Isetyenziselwa ukunyanga isifo esinganyangekiyo semiphunga (COPD) kubantu abadala. I-COPD liqela lezifo zemiphunga ezibandakanya i-bronchitis engapheliyo kunye ne-emphysema.

Impendulo edibeneyo yi-bronchodilator. Olu luhlobo lonyango olunceda ukuvula iivesi zokuphefumla kwimiphunga yakho, kwaye uyaphefumlela.

Phambi kokuba ugqirha wakho amisele i-Combivent Respimat, kuya kufuneka ukuba sele usebenzisa i-bronchodilator kwifom ye-aerosol. Kwakhona, kufuneka ube ne-bronchospasms (ukuqina kwemisipha kwindlela yakho yomoya) kwaye ufuna i-bronchodilator yesibini.

Impendulo edibeneyo inamachiza amabini. Eyokuqala yi-ipratropium, eyinxalenye yodidi lweziyobisi ezibizwa ngokuba yi-anticholinergics. (Udidi lweziyobisi liqela lamayeza asebenza ngendlela efanayo.) Iyeza lesibini yialbuterol, eyinxalenye yodidi lweziyobisi ekuthiwa yi-beta2-adrenergic agonists.

Impendulo edibeneyo iza njenge-inhaler. Igama lesixhobo se-inhaler yi-Respimat.


Ukusebenza ngempumelelo

Kwisifundo seklinikhi, isiPhenduli esiHlangeneyo sisebenze ngcono kune-ipratropium yodwa (esinye sezithako ezikwiMpendulo edibeneyo). Abantu abathathe i-Combivent Respimat banokuvuthela umoya ngamandla ngaphezulu komzuzwana (owaziwa njenge-FEV1) xa kuthelekiswa nabantu abathathe ipratropium.

I-FEV1 eqhelekileyo yomntu oneCOPD imalunga ne-1.8 yeelitha. Ukonyuka kwe-FEV1 kubonisa ukuhamba komoya okungcono kwimiphunga yakho. Kolu phononongo, abantu babenokuphucuka kwi-FEV1 yabo kwiiyure ezine zokuthatha ichiza elinye. Kodwa i-FEV1 yabantu abathathe i-Combivent Respimat iphucule i-milliliters ezingama-47 ngaphezulu kunabantu abathathe ipratropium bodwa.

Impendulo edibeneyo yohlobo

Impendulo edibeneyo ifumaneka kuphela njengeyeza elinegama lophawu. Okwangoku ayifumaneki ngendlela eqhelekileyo.

Impendulo yokudibanisa inezinto ezimbini ezisebenzayo zeziyobisi: ipratropium kunye nealbuterol.

Ipratropium kunye nealbuterol ziyafumaneka njengechiza elenziwa lafana nelo lisetyenziselwa ukunyanga iCOPD. Nangona kunjalo, ichiza elenziwe lafana nalawo aveliswe ngumenzi likwimo eyahlukileyo kuneCompivent Respimat, eza njenge-inhaler. Ichiza elenza lafana nalawo aveliswe ngumenzi liza njengesisombululo (ingxubevange engamanzi) esetyenziswe kwisixhobo ekuthiwa yi-nebulizer. I-nebulizer ijika iyeza libe yinkungu oyifaka ngaphakathi kwimaski okanye kumlomo.


Amachiza enziwe afana nalawo enziwa ngumenzi nawo eza ngamandla ahlukileyo kuneCompivent Respimat, equlathe i-20 mcg ye-ipratropium kunye ne-100 mcg ye-albuterol. Amachiza enziwe afana nalawo aveliswe ngumenzi ane-0.5 mg ye-ipratropium kunye ne-2.5 mg ye-albuterol.

Umthamo wokuPhendula ngokudibeneyo

Idosi yempendulo edibeneyo ugqirha wakho aya kuyixhomekeka ekubeni sisifo esinganyangekiyo sesifo semiphunga (COPD).

Olu lwazi lulandelayo luchaza iidosi eziqhelekileyo ezisetyenziswayo okanye ezicetyiswayo. Nangona kunjalo, qiniseka ukuthatha idosi ekumisela ugqirha wakho. Ugqirha wakho uya kumisela eyona idosi ilungele iimfuno zakho.

Iifom zamachiza kunye namandla

Impendulo edibeneyo iza iziqwenga ezibini:

  • isixhobo se-inhaler
  • iCartridge equlathe iyeza (ipratropium kunye nealbuterol)

Ngaphambi kokuba usebenzise isixhobo esiDibeneyo sokuPhendula okokuqala, kuya kufuneka ubeke iCartridge kwi-inhaler. (Jonga icandelo elithi "Uyisebenzisa kanjani iMpendulo edibeneyo" apha ngezantsi.)

Inhalation nganye (ukukhukhumeza) kweyeza liqukethe i-20 mcg ye-ipratropium kunye ne-100 mcg ye-albuterol. Kukho ukukhukhumeza okuyi-120 kwikhatriji nganye.


Isisombululo seCOPD

Umthamo oqhelekileyo weCOPD kukukhuphela omnye, amaxesha amane ngemini. Elona thamo liphezulu kukukhupha omnye, amaxesha amathandathu ngosuku.

Kuthekani ukuba ndiphose idosi?

Ukuba uphoswa ithamo leMpendulo edibeneyo, linda de kube lixesha ledosi yakho elandelayo ehleliweyo. Emva koko qhubeka uthatha iyeza njengesiqhelo.

Ukukunceda uqiniseke ukuba awuphosi idosi, zama ukuseta isikhumbuzi kwifowuni yakho. Ixesha leyeza linokuba luncedo, nalo.

Ngaba kuya kufuneka ndisebenzise eli chiza ixesha elide?

Impendulo edibeneyo yenzelwe ukuba isetyenziswe njengonyango lwexesha elide. Ukuba wena nogqirha ugqibe ukuba ichiza likhuselekile kwaye liyasebenza kuwe, uya kulithatha ixesha elide.

Iziphumo ezihlangeneyo zokuphendula

Ukuphendula ngokudibeneyo kunokubangela iziphumo ebezingalindelekanga ezinobulali okanye ezinobuzaza. Olu luhlu lulandelayo luqulathe ezinye zeziphumo ebezingalindelekanga ezinokubakho ngelixa kuthathwa umphendulwano wokudibana. Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga ezinokubakho.

Ngolwazi oluthe kratya malunga neziphumo ebezingalindelekanga zokudibana, thetha nogqirha wakho okanye usokhemesti. Banokukunika iingcebiso malunga nendlela yokujongana nayo nayiphi na imiphumela emibi enokuthi ikhathaze.

Iziphumo eziqhelekileyo ezichaphazelekayo

Iziphumo eziqhelekileyo ezichaphazelekayo zempendulo edibeneyo zingabandakanya:

  • ukukhohlela
  • ukuphefumla kancinci okanye unengxaki yokuphefumla
  • intloko ebuhlungu
  • Usulelo olunokuchaphazela ukuphefumla kwakho okunje nge-bronchitis okanye umkhuhlane

Uninzi lweziphumo ebezingalindelekanga zinokuhamba zingaphelanga iintsuku okanye iiveki ezimbalwa. Ukuba zinzima kakhulu okanye azihambi, thetha nogqirha wakho okanye usokhemesti.

Iziphumo ebezingalindelekanga ezimandundu

Iziphumo ebezingalindelekanga ezimandundu ezivela kwiMpendulo edibeneyo aziqhelekanga, kodwa zinokwenzeka. Shayela ugqirha wakho ngokukhawuleza ukuba unemiphumo emibi. Tsalela umnxeba ku-911 ukuba iimpawu zakho ziziva zisongela ubomi okanye ukuba ucinga ukuba unempilo kaxakeka.

Iziphumo ebezingalindelekanga ezimandundu kunye neempawu zazo zinokubandakanya oku kulandelayo:

  • I-bronchospasm ephikisayo (ukuvutha okanye ubunzima bokuphefumla obuba mandundu)
  • Iingxaki zamehlo. Iimpawu zingabandakanya:
    • i-glaucoma (ukwanda koxinzelelo ngaphakathi kwiso)
    • iintlungu zamehlo
    • iihalos (ukubona izangqa eziqaqambileyo ezijikeleze izibane)
    • ukungaboni kakuhle
    • isiyezi
  • Ingxaki yokuchama okanye iintlungu xa uchama
  • Iingxaki zentliziyo. Iimpawu zingabandakanya:
    • ukukhawuleza kwentliziyo
    • iintlungu zesifuba
  • Hypokalemia (amanqanaba asezantsi e-potassium). Iimpawu zingabandakanya:
    • ukudinwa (ukunqongophala kwamandla)
    • ubuthathaka
    • izihlunu zemithambo
    • ukuqhina
    • Ukubetha kwentliziyo (imvakalelo yokutsiba okanye ukubetha kwentliziyo)

Iinkcukacha zesiphumo

Unokuzibuza ukuba zenzeka kangaphi ezinye iziphumo ebezingalindelekanga ngeli chiza. Nazi ezinye iinkcukacha kwezinye zeziphumo ebezingalindelekanga ezinokubangelwa leli chiza.

Ukuphendula ngokuchaseneyo

Njengoninzi lweziyobisi, abanye abantu banokuba neempendulo ezingafunekiyo emva kokuthatha i-Combivent Respimat. Iimpawu zokuphendula kancinci kunokubandakanya:

  • irhashalala
  • ukucheba
  • ukucoca (ukufudumala nokubomvu kwesikhumba sakho)

Impendulo eyingozi kakhulu inqabile kodwa inokwenzeka. Iimpawu zokungaziphathi kakuhle kunokubandakanya:

  • ukudumba phantsi kolusu lwakho, ikakhulu kwiinkophe zakho, imilebe, izandla, okanye iinyawo
  • ukudumba kolwimi lwakho, umlomo, okanye umqala
  • ingxaki yokuphefumla

Ayaziwa ukuba bangaphi abantu abaye bahlaselwa emva kokuthatha i-Combivent Respimat.

Ukuba uneempendulo ezigwenxa kwi-Combivent Respimat, tsalela ugqirha kwangoko. Tsalela umnxeba ku-911 ukuba iimpawu zakho ziziva zisongela ubomi okanye ukuba ucinga ukuba unempilo kaxakeka.

Umkhuhlane

Ukuthatha impendulo ngokudibeneyo kunokubangela ukuba ufumane umkhuhlane. Isifundo seklinikhi sijonge abantu abanesifo esinganyangekiyo semiphunga (COPD) abathathe i-Combivent Respimat okanye i-ipratropium (isithako kwi-Combivent Respimat). Kolu phando, iipesenti ezi-3 zabantu abathathe i-Combivent Respimat babenengqele. Ipesenti ezintathu zabantu abathathe ipratropium nabo babenengqele.

Ingqele inokuthi ibe mandundu ngakumbi kwiimpawu zeCOPD, ezinje ngokuphefumla, ukuvutha kunye nokukhohlela. Kungenxa yokuba umkhuhlane unokuchaphazela imiphunga yakho. Unokuzama ukuthintela ukubanda ngezi ngcebiso:

  • Hlamba izandla zakho rhoqo.
  • Nciphisa unxibelelwano naye nabani na ogulayo.
  • Kulumkele ukwabelana ngezinto ezizezakho, ezifana nokusela iiglasi kunye neebrashi zamazinyo, kunye nabanye abantu.
  • Ukucoca izibambo zeminyango kunye nokutshintsha ukukhanya.

Ukuba uhlakulela ukubanda ngelixa uthatha i-Combivent Respimat, thetha nogqirha wakho okanye usokhemesti. Banokukucebisa ngendlela yokulawula iimpawu zakho ezibandayo kunye neCOPD.

Iingxaki zamehlo

Ukuthatha impendulo edibeneyo kunokubangela iingxaki ngamehlo akho, njengeglaucoma entsha okanye eyandayo. I-Glaucoma kukunyuka koxinzelelo ngaphakathi kwamehlo okunokubangela ukonakala kwamehlo. Ayaziwa ukuba bangaphi abantu abaye banengxaki yamehlo emva kokuthatha i-Combivent Respimat.

Kuyenzeka ukuba ufefe isiPhenduli esiHlangeneyo emehlweni akho ngengozi xa uphefumla ichiza. Ukuba oku kuyenzeka, unokuba nentlungu yamehlo okanye umbono ophazamisayo. Ke xa usebenzisa i-Combivent Respimat, zama ukunqanda ukutshiza iyeza emehlweni akho.

Ukuba uthatha i-Combivent Respimat kwaye ubona iihalos (izangqa eziqaqambileyo ezijikeleze izibane), uye wabona umbono, okanye uqaphele ezinye iingxaki zamehlo, xelela ugqirha wakho. Ugqirha wakho angayeka ukudibanisa okanye akutshintshele kwelinye iyeza. Kuxhomekeka kwiimpawu zakho, banokuyinyanga ingxaki yamehlo akho.

Ezinye iindlela zokuPhendula ngokudibeneyo

Amanye amachiza akhoyo anokunyanga isifo esinganyangekiyo semiphunga (COPD). Abanye banokukulungela ngcono kunabanye. Ukuba unomdla ekufumaneni enye indlela yokuPhendula ngokudibeneyo, thetha nogqirha wakho. Banokukuxelela ngamanye amayeza anokukusebenzela.

Phawula: Amanye amachiza adweliswe apha asetyenziswa ngaphandle kwelebheli ukunyanga le miqathango. Ukusetyenziswa kwelebula engekho xa kusebenze iyeza elamkelweyo ukunyanga imeko enye lisetyenziselwa ukunyanga imeko eyahlukileyo.

Ezinye iindlela zeCOPD

Imizekelo yezinye iziyobisi ezisetyenziselwa ukunyanga i-COPD ibandakanya:

  • i-bronchodilators emfutshane, efana nelevoalbuterol (Xopenex)
  • I-bronchodilators esebenza ixesha elide, njenge salmeterol (Serevent)
  • ii-corticosteroids, ezinje ngefluticasone (Flovent)
  • I-bronchodilators ezimbini ezisebenza ixesha elide (ngokudibeneyo), ezinje nge tiotropium / olodaterol (Stiolto)
  • i-corticosteroid kunye ne-bronchodilator esebenza ixesha elide (ngokudibeneyo), njenge-budesonide / formoterol (Symbicort)
  • i-phosphodiesterase-4 inhibitors, enjenge roflumilast (Daliresp)
  • i-methylxanthines, efana ne-theophylline
  • i-steroids, njenge-prednisone (iDeltasone, iRayos)

Esinye isifo esinokwenza kube nzima ukuphefumla sisifuba, esibangela ukudumba kwiindlela zakho zomoya. Ngenxa yokuba zombini i-COPD kunye ne-asthma zingakhokelela kwiingxaki zokuphefumla, amanye amayeza e-asthma angasetyenziselwa ngaphandle kwelebula ukunyanga iimpawu zeCOPD. Umzekelo wamayeza anokusetyenziswa ngaphandle kwelebheli ye-COPD yindibaniselwano ye-mometasone / formoterol (Dulera).

Impendulo edibeneyo ngokuchasene neSymbicort

Usenokuzibuza ukuba iphendula njani ngokudibeneyo xa ithelekiswa namanye amayeza amiselweyo ukuze asetyenziswe ngokufanayo. Apha sijonga indlela i-Combivent Respimat kunye ne-Symbicort ezifanayo kunye ezahlukeneyo.

Sebenzisa

Ulawulo lwezoKutya kunye noLawulo lweziyobisi (i-FDA) luvumile zombini i-Combivent Respimat kunye ne-Symbicort ukunyanga isifo esinganyangekiyo semiphunga (COPD) kubantu abadala. I-COPD liqela lezifo zemiphunga ezibandakanya i-bronchitis engapheliyo kunye ne-emphysema.

Phambi kokuba ugqirha wakho anike i-Combivent Respimat, kuya kufuneka usebenzise i-bronchodilator kwifom ye-aerosol. Olu luhlobo lonyango olunceda ukuvula iivesi zokuphefumla kwimiphunga yakho, kwaye uyaphefumlela. Kwakhona, kusafuneka ube ne-bronchospasms (ukuqina kwemisipha kwindlela yakho yomoya) kwaye ufuna i-bronchodilator yesibini.

I-Symbicort ikwavunyiwe ukunyanga isifuba kubantu abadala nakubantwana abaneminyaka emi-6 nangaphezulu.

Akukho mpendulo idibeneyo okanye iSymbicort yenzelwe ukuba isetyenziswe njengeyeza lokuhlangula i-COPD yokuphefumla ngokukhawuleza.

Iifom zeziyobisi kunye nolawulo

Impendulo edibeneyo ineziyobisi ipratropium kunye nealbuterol. Symbicort iqulethe iziyobisi i-budesonide kunye ne-formoterol.

Zombini iimpendulo eziHlanganisiweyo kunye neSymbicort ziza kubini:

  • isixhobo se-inhaler
  • iCartridge (Combivent Respimat) okanye ibhokisi (Symbicort) equlathe iyeza

Inhalation nganye (inkuku) ye-Combivent Respimat iqulethe i-20 mcg ye-ipratropium kunye ne-100 mcg ye-albuterol. Kukho ukukhukhumeza okuyi-120 kwikhatriji nganye.

Ukukhuhla ngakunye kweSymbicort kuqulethe i-160 mcg ye-budesonide kunye ne-4.5 mcg ye-formoterol ukunyanga i-COPD. Kukho ama-60 okanye i-120 akhukhumezayo kwibhokisi nganye.

Ukuphendula ngokudibeneyo, idosi eqhelekileyo ye-COPD kukukhuphela omnye, amaxesha amane ngemini. Elona thamo liphezulu kukukhupha omnye, amaxesha amathandathu ngosuku.

Kwi-Symbicort, idosi eqhelekileyo ye-COPD kukukhukhumala kabini, amaxesha amabini ngosuku.

Iziphumo kunye neengozi

Impendulo edibeneyo kunye neSymbicort zombini zineziyobisi kwiklasi efanayo yamayeza. Ke ngoko, omabini la mayeza anokubangela iziphumo ezifanayo. Apha ngezantsi kunemizekelo yeziphumo ebezingalindelekanga.

Iziphumo eziqhelekileyo ezichaphazelekayo

Olu luhlu lunemizekelo yeziphumo ebezingalindelekanga eziqhelekileyo ezinokuthi zenzeke ngokudibana kwempendulo, kunye neSymbicort, okanye zombini iziyobisi (xa zithathwa ngokwahlukeneyo).

  • Ngaba inokwenzeka ngokudibana kwempendulo:
    • ukukhohlela
  • Inokwenzeka ngeSymbicort:
    • iintlungu esiswini sakho, emqolo, okanye emqaleni
  • Inokwenzeka kunye neempendulo ezidibeneyo kunye ne-Symbicort:
    • ukuphefumla kancinci okanye unengxaki yokuphefumla
    • intloko ebuhlungu
    • Usulelo olunokuchaphazela ukuphefumla kwakho okunje nge-bronchitis okanye umkhuhlane

Iziphumo ebezingalindelekanga ezimandundu

Olu luhlu lunemizekelo yeziphumo ebezingalindelekanga ezinokuthi zenzeke ngokudibana kwempendulo, kunye neSymbicort, okanye zombini iziyobisi (xa zithathwa ngokwahlukeneyo).

  • Ngaba inokwenzeka ngokudibana kwempendulo:
    • ingxaki yokuchama okanye intlungu xa uchama
    • i-hypokalemia (amanqanaba asezantsi e-potassium)
  • Inokwenzeka ngeSymbicort:
    • umngcipheko ophezulu wosulelo, njengosulelo olusemlonyeni wakho olubangelwa ngundo okanye intsholongwane
    • iingxaki ze-adrenal gland, kubandakanya amanqanaba asezantsi e-cortisol
    • i-osteoporosis okanye ubuncinci bamaminerali amathambo
    • ukukhula okucothayo ebantwaneni
    • amanqanaba e-potassium asezantsi
    • amanqanaba aphezulu eswekile yegazi
  • Inokwenzeka kunye neempendulo eziHlanganisiweyo kunye ne-Symbicort:
    • i-bronchospasm ephikisayo (ukuvutha okanye ingxaki yokuphefumla eya isiba mandundu)
    • negazi lakho
    • iingxaki zentliziyo, ezinje ngesantya sentliziyo esikhawulezayo okanye iintlungu esifubeni
    • iingxaki zamehlo, njengokuqaqamba kweglaucoma

Ukusebenza ngempumelelo

Impendulo edibeneyo kunye ne-Symbicort banezinto ezahlukileyo ezisetyenzisiweyo ezisetyenziswa yi-FDA, kodwa zombini zisetyenziselwa ukunyanga i-COPD.

La machiza awakhange athelekiswe ngokuthe ngqo kwizifundo zeklinikhi, kodwa izifundo zifumene zombini i-Combivent Respimat kunye ne-Symbicort ukuba isebenze ekunyangeni i-COPD.

Iindleko

Impendulo edibeneyo kunye ne Symbicort zombini zineziyobisi ezinamagama. Okwangoku azikho iintlobo zohlobo oluthile lwamayeza.

Nangona kunjalo, i-FDA ivume i-ipratropium kunye ne-albuterol (izinto ezisebenzayo kwi-Combivent Respimat) njengechiza elenziwe lafana nelo lisetyenziselwa ukunyanga i-COPD. Eli chiza liza ngendlela eyahlukileyo kuneMpendulo edibeneyo. Ichiza elenza lafana nalawo aveliswe ngumenzi liza njengesisombululo (ingxubevange engamanzi) esetyenziswe kwisixhobo ekuthiwa yi-nebulizer. Le nebulizer ijika iyeza libe yinkungu oyifaka ngaphakathi kwimaski okanye kumlomo.

Ngokwengqikelelo yeGoodRx.com, iSymbicort ixabisa ngaphantsi kweMpendulo yokuHlanganisa. Amachiza enziwe afana nalawo aveliswe ngumenzi yi-ipratropium kunye ne-albuterol iya kuba ngexabiso eliphantsi kuneCompivent Respimat okanye iSymbicort. Elona xabiso uza kulihlawula kula machiza lixhomekeke kwisicwangciso sakho seinshurensi, indawo okuyo, nakwikhemesti oyisebenzisayo.

Impendulo edibeneyo vs. Impendulo yeSpiriva

Usenokuzibuza ukuba ipendulo edibeneyo ithelekiswa njani na namanye amayeza amiselweyo ukuze asetyenziswe ngokufanayo. Apha sijonga indlela i-Combivent Respimat kunye ne-Spiriva Respimat ziyafana kwaye zahlukile.

Sebenzisa

Ulawulo lwezoKutya kunye noLawulo lweziyobisi (i-FDA) luvumile zombini i-Combivent Respimat kunye ne-Spiriva Respimat ukunyanga isifo esinganyangekiyo semiphunga (COPD) kubantu abadala. I-COPD liqela lezifo zemiphunga ezibandakanya i-bronchitis engapheliyo kunye ne-emphysema.

Phambi kokuba ugqirha wakho anike i-Combivent Respimat, kuya kufuneka usebenzise i-bronchodilator kwifom ye-aerosol. Olu luhlobo lonyango olunceda ukuvula iivesi zokuphefumla kwimiphunga yakho, kwaye uyaphefumlela. Kwakhona, kusafuneka ube ne-bronchospasms (ukuqina kwemisipha kwindlela yakho yomoya) kwaye ufuna i-bronchodilator yesibini.

I-Spiriva Respimatis ikwavunyiwe ukunyanga isifuba kubantu abadala nakubantwana abaneminyaka emi-6 nangaphezulu.

Akukho mpendulo idibeneyo okanye iSpiriva Respimat yenzelwe ukuba isetyenziswe njengeyeza lokuhlangula i-COPD yokuphefumla kwangoko.

Iifom zeziyobisi kunye nolawulo

Iphendula ngokudibeneyo ineziyobisi ipratropium kunye nealbuterol. I-Spiriva Respimat iqulethe i-tiotropium yeziyobisi.

Zombini iimpendulo ezidibeneyo kunye neSpiriva Respimat ziza iziqwenga ezibini:

  • isixhobo se-inhaler
  • iCartridge equlethe iyeza

Inhalation nganye (inkuku) ye-Combivent Respimat iqulethe i-20 mcg ye-ipratropium kunye ne-100 mcg ye-albuterol. Kukho ukukhukhumeza okuyi-120 kwikhatriji nganye.

Ukukhuhla ngakunye kweSpiriva Respimat iqulethe i-2.5 mcg ye-tiotropium yokunyanga i-COPD. Iikhatriji ziza ngokukhukhumala ezingama-60 kuzo.

Ukuphendula ngokudibeneyo, idosi eqhelekileyo ye-COPD kukukhuphela omnye, amaxesha amane ngemini. Elona thamo liphezulu kukukhupha omnye, amaxesha amathandathu ngosuku.

I-Spiriva Respimat, idosi eqhelekileyo ye-COPD kukukhukhumeza kabini, kanye ngemini.

Iziphumo kunye neengozi

Impendulo edibeneyo kunye neSpiriva Respimat zombini ziqulethe amayeza kwiklasi efanayo yeziyobisi. Ke ngoko, omabini la mayeza anokubangela iziphumo ezifanayo.Apha ngezantsi kunemizekelo yeziphumo ebezingalindelekanga.

Iziphumo eziqhelekileyo ezichaphazelekayo

Olu luhlu lunemizekelo yeziphumo ebezingalindelekanga eziqhelekileyo ezinokuthi zenzeke ngokudibana kwempendulo, ngeSpiriva, okanye zombini iziyobisi (xa zithathwa ngokwahlukeneyo).

  • Ngaba inokwenzeka ngokudibana kwempendulo:
    • zimbalwa iziphumo ebezingalindelekanga eziqhelekileyo
  • Inokwenzeka ngeSpiriva Respimat:
    • umlomo owomileyo
  • Ngaba zinokwenzeka zombini ngokudibeneyo kwempendulo kunye neSpiriva Respimat:
    • ukukhohlela
    • ukuphefumla kancinci okanye unengxaki yokuphefumla
    • intloko ebuhlungu
    • Usulelo olunokuchaphazela ukuphefumla kwakho, isifo esifana nesikaqaqamba okanye umkhuhlane

Iziphumo ebezingalindelekanga ezimandundu

Olu luhlu lunemizekelo yeziphumo ebezingalindelekanga ezinokuthi zenzeke ngokudibana kwempendulo, ngeSpiriva, okanye zombini iziyobisi (xa zithathwa ngokwahlukeneyo).

  • Ngaba inokwenzeka ngokudibana kwempendulo:
    • iingxaki zentliziyo, ezinje ngesantya sentliziyo esikhawulezayo okanye iintlungu esifubeni
    • i-hypokalemia (amanqanaba asezantsi e-potassium)
  • Inokwenzeka ngeSpiriva Respimat:
    • zimbalwa iziphumo ebezingalindelekanga ezimandundu
  • Ngaba zinokwenzeka zombini ngokudibeneyo kwempendulo kunye neSpiriva Respimat:
    • i-bronchospasm ephikisayo (ukuvutha okanye ingxaki yokuphefumla eya isiba mandundu)
    • negazi lakho
    • iingxaki zamehlo, njenge-glaucoma entsha okanye eyandayo
    • ingxaki yokuchama okanye intlungu xa uchama

Ukusebenza ngempumelelo

I-Respimat edibeneyo kunye ne-Spiriva Respimat zinokusetyenziswa okwahlukileyo okuvunyiweyo yi-FDA, kodwa la machiza mabini asetyenziselwa ukunyanga i-COPD.

La machiza awathelekiswanga ngokuthe ngqo kwizifundo zeklinikhi, kodwa izifundo zifumene zombini i-Combivent Respimat kunye ne-Spiriva Respimat ukuba isebenze kunyango lwe-COPD.

Iindleko

Impendulo edibeneyo kunye neSpiriva Respimat zombini zineziyobisi ezinamagama. Okwangoku azikho iintlobo zohlobo oluthile lwamayeza.

Nangona kunjalo, i-FDA ivume i-ipratropium kunye ne-albuterol (izinto ezisebenzayo kwi-Combivent Respimat) njengechiza elenziwe lafana nelo lisetyenziselwa ukunyanga i-COPD. Eli chiza liza ngendlela eyahlukileyo kuneMpendulo edibeneyo. Ichiza elenza lafana nalawo aveliswe ngumenzi liza njengesisombululo (ingxubevange engamanzi) esetyenziswe kwisixhobo ekuthiwa yi-nebulizer. Le nebulizer ijika iyeza libe yinkungu oyifaka ngaphakathi kwimaski okanye kumlomo.

Ngokwengqikelelo yeGoodRx.com, i-Combivent Respimat kunye ne-Spiriva ngokubanzi zibiza malunga nokufanayo. Amachiza enziwe afana nalawo aveliswe ngumenzi i-ipratropium kunye ne-albuterol aya kuhlala engabizi kakhulu kune-Combivent Respimat okanye i-Spiriva. Elona xabiso uza kulihlawula kula machiza lixhomekeke kwisicwangciso sakho seinshurensi, indawo okuyo, nakwikhemesti oyisebenzisayo.

Ukusetyenziswa kweempendulo ngokudibeneyo

Ulawulo lwezoKutya kunye noLawulo lweziyobisi (i-FDA) livuma amayeza amiselweyo anje nge-Combivent Respimat ukunyanga iimeko ezithile. Impendulo edibeneyo inokusetyenziselwa ngaphandle kwelebheli yezinye iimeko. Ukusetyenziswa kwelebula engekho xa kusebenze iyeza elamkelweyo ukunyanga imeko enye lisetyenziselwa ukunyanga imeko eyahlukileyo.

Impendulo edibeneyo yesifo esinganyangekiyo semiphunga

I-FDA ivume i-Combivent Respimat ukunyanga isifo esinganyangekiyo semiphunga (COPD) kubantu abadala. I-COPD liqela lezifo zemiphunga ezibandakanya i-bronchitis engapheliyo kunye ne-emphysema.

I-bronchitis engapheliyo ibangela ukuba iityhubhu zomoya kwimiphunga yakho zincinci, zidumbile, kwaye ziqokelele i-mucus. Oku kwenza kube nzima ukuba umoya udlule kwimiphunga yakho.

I-Emphysema itshabalalisa iingxowa zomoya kwimiphunga yakho ngokuhamba kwexesha. Xa kunemingxunya yomoya embalwa, kuba nzima ukuphefumla.

Zombini i-bronchitis enganyangekiyo kunye ne-emphysema zikhokelela kwingxaki yokuphefumla, kwaye kuyinto eqhelekileyo ukuba zombini ezi meko.

Phambi kokuba ugqirha wakho anike i-Combivent Respimat, kuya kufuneka usebenzise i-bronchodilator kwifom ye-aerosol. Olu luhlobo lonyango olunceda ukuvula iivesi zokuphefumla kwimiphunga yakho, kwaye uyaphefumlela. Kwakhona, kusafuneka ube ne-bronchospasms (ukuqina kwemisipha kwindlela yakho yomoya) kwaye ufuna i-bronchodilator yesibini.

Ukusebenza ngempumelelo

Kwisifundo seklinikhi, isiPhenduli esiHlangeneyo sisebenze ngcono kune-ipratropium yodwa (esinye sezithako ezikwiMpendulo edibeneyo). Abantu abathathe i-Combivent Respimat banokuvuthela umoya ngamandla ngaphezulu komzuzwana (owaziwa njenge-FEV1) xa kuthelekiswa nabantu abathathe ipratropium.

I-FEV1 eqhelekileyo yomntu oneCOPD imalunga ne-1.8 yeelitha. Ukonyuka kwe-FEV1 kubonisa ukuhamba komoya okungcono kwimiphunga yakho. Kolu phononongo, abantu babenokuphucuka kwi-FEV1 yabo kwiiyure ezine zokuthatha ichiza elinye. Kodwa i-FEV1 yabantu abathathe i-Combivent Respimat yaphucula i-47 milliliters ngaphezulu kwe-FEV1 yabantu abathathe ipratropium yodwa.

Ukusetyenziswa kwelebheli engaphandle kwempendulo edibeneyo

Ukongeza kusetyenziso oludweliswe apha ngasentla, isiPhenduli esiHlangeneyo sinokusetyenziselwa ngaphandle kwelebheli yolunye usetyenziso. Ukusetyenziswa kweziyobisi ezingekho kwilebula kuxa iziyobisi ezivunyiweyo zisetyenziselwa ukusetyenziswa kwesinye zisetyenziselwa enye eyahlukileyo engavunyelwanga.

Impendulo edibeneyo yesifuba

I-FDA ayivumanga i-Combivent Respimat yokunyanga ukuhlaselwa sisifo sombefu. Nangona kunjalo, ugqirha wakho unokuyalela ukuba ichiza lingabikho kwileyibhile ukuba ezinye iindlela zonyango ezivunyiweyo azikusebenzeli. Isifuba semiphunga yimeko yemiphunga apho iindlela zakho zomoya ziqinisa, zidumbe, kwaye zigcwalise i-mucus. Oku kukhokelela ekuphefumlweni kwaye kwenza kube nzima ukuphefumla.

Ukusetyenziswa ngokudibeneyo kwempendulo kunye nezinye iziyobisi

Impendulo edibeneyo isetyenziswa kunye nezinye izifo ezingapheliyo zesifo semiphunga (COPD) ukunyanga iCOPD. Ukuba amayeza akho e-COPD anganciphisi iimpawu zakho, ugqirha wakho unokumisela i-Combivent Respimat njengechiza elongezelelweyo.

Imizekelo yamayeza e-bronchodilator anokusetyenziswa kunye neempendulo ezihlangeneyo zibandakanya:

  • i-bronchodilators emfutshane, efana nelevoalbuterol (Xopenex)
  • I-bronchodilators esebenza ixesha elide, njenge salmeterol (Serevent)

La mayeza anokuba nezithako ezifanayo nezo zikwiMpendulo edibeneyo. Ukuthatha ezi zinto ngokudibanisa impendulo kunokwenza ukuba iziphumo ebezingalindelekanga zibe mbi kakhulu. (Nceda ubone icandelo leempendulo zempendulo ngokudibeneyo ukuze ufumane iinkcukacha ezingaphezulu.) Ugqirha wakho unokujonga iimpembelelo zakho okanye akutshintshele kwelinye iyeza xa kufuneka njalo.

Uyisebenzisa njani iMpendulo edibeneyo

Kuya kufuneka uthathe i-Combivent Respimat ngokomyalelo kagqirha wakho okanye ngemiyalelo yezempilo.

Impendulo edibeneyo iza iziqwenga ezibini:

  • isixhobo se-inhaler
  • iCartridge equlethe iyeza

Uya kuthatha i-Respimat edibeneyo ngokuyihogela. Ukufunda ukuba ungayilungisa njani inhaler yakho kwaye uyisebenzise yonke imihla, bukela ezi vidiyo kwiwebhusayithi yeCompivent Respimat. Unokulandela imiyalelo yenyathelo ngenyathelo kunye neefoto ezivela kule webhusayithi.

Nini ukuthatha

Umthamo oqhelekileyo kukuphefumla okukodwa, amaxesha amane ngemini. Elona thamo liphezulu kukudonsa ngaphakathi, izihlandlo ezithandathu ngemini. Idosi yempendulo edibeneyo kufuneka ihlale ubuncinci iiyure ezine ukuya kwezintlanu. Ukuthintela ukuvuka ebusuku uthathe idosi, beka iidosi zakho emini xa uvukile.

Ukukunceda uqiniseke ukuba awuphosi idosi, beka isikhumbuzi kwifowuni yakho. Unokufumana ixesha lokunyanga.

Iindleko zokudibana kwempendulo

Njengawo onke amayeza, iindleko zempendulo edibeneyo zinokwahluka.

Ixabiso langempela oza kulihlawula lixhomekeke kwisicwangciso sakho seinshurensi, indawo okuyo, kunye nekhemesti oyisebenzisayo.

Uncedo lwezezimali kunye neinshurensi

Ukuba ufuna inkxaso yemali ukuhlawulela i-Combivent Respimat, okanye ukuba ufuna uncedo lokuqonda i-inshurensi yakho, uncedo luyafumaneka.

I-Boehringer Ingelheim Pharmaceuticals, Inc, umvelisi we-Combivent Respimat, unikezela ngekhadi lokulondoloza elinokunceda ukunciphisa iindleko zonyango lwakho. Ngolwazi oluthe kratya kunye nokufumanisa ukuba uyilungele na inkxaso, tsalela umnxeba ku-800-867-1052 okanye undwendwele iwebhusayithi yenkqubo.

Impendulo edibeneyo kunye notywala

Ngeli xesha, utywala abaziwa ukuba buhlangana neCompivent Respimat. Nangona kunjalo, ukusela utywala rhoqo kungakhokelela kwisifo esinganyangekiyo semiphunga (COPD). Xa usela kakhulu, imiphunga yakho iba nexesha elinzima lokugcina umoya wakho ucacile.

Ukuba unemibuzo malunga nokusela utywala kunye nokuthatha i-Combivent Respimat, thetha nogqirha wakho.

Ukudibana kwempendulo edibeneyo

Impendulo edibeneyo inokusebenzisana namanye amayeza. Inokuphinda inxibelelane nezinye izongezo kunye nokutya okuthile.

Unxibelelwano olwahlukileyo kunokubangela iziphumo ezahlukeneyo. Umzekelo, unxibelelwano oluthile lunokuphazamisa ukusebenza kakuhle kwesiyobisi. Olunye unxibelelwano lunokunyusa inani leziphumo ebezingalindelekanga okanye lubenze banzima ngakumbi.

Impendulo edibeneyo kunye namanye amayeza

Apha ngezantsi luluhlu lwamayeza anokuthi asebenzisane neMpendulo edibeneyo. Olu luhlu alunazo zonke iziyobisi ezinokuthi zinxibelelane ne-Combivent Respimat.

Ngaphambi kokuba uthathe i-Combivent Respimat, thetha nogqirha wakho kunye nosokhemesti. Baxelele ngawo onke amayeza kagqirha, ekhawuntareni, kunye nezinye iziyobisi ozithathayo. Baxelele malunga nazo naziphi na iivithamini, amayeza esintu kunye nezixhasi ozisebenzisayo. Ukwabelana ngolu lwazi kunokukunceda uphephe unxibelelwano olunokubakho.

Ukuba unemibuzo malunga nokunxibelelana kweziyobisi okunokuchaphazela, buza ugqirha wakho okanye usokhemesti.

Impendulo edibeneyo kunye nezinye i-anticholinergics kunye / okanye i-beta-adrenergic agonists

Ukuthatha impendulo ngokudibeneyo kunye nezinye i-anticholinergics kunye / okanye i-beta2-adrenergic agonists inokwenza iziphumo zakho zecala zibe nzima kakhulu. (Nceda ujonge icandelo leempendulo "eziHlangeneyo zeMpendulo" ukuze ufumane ezinye iinkcukacha.)

Imizekelo yezinye i-anticholinergics kunye ne-beta2-adrenergic agonists ibandakanya:

  • i-anticholinergics, enje nge diphenhydramine (Benadryl), tiotropium (Spiriva)
  • i-beta2-adrenergic agonists, enje ngealbuterol (Ventolin)

Ngaphambi kokuba uthathe i-Combivent Respimat, xelela ugqirha wakho ukuba uthatha na la machiza. Banokubeka iliso ngexesha lonyango oluhlangeneyo lweempendulo okanye bakutshintshele kwelinye iyeza.

Impendulo edibeneyo kunye noxinzelelo oluthile lwegazi

Ukuthatha impendulo ngokudibeneyo kunye noxinzelelo oluphezulu lweyeza kunokunciphisa amanqanaba e-potassium emzimbeni wakho okanye kuthintele i-Combivent Respimat ekusebenzeni ngokufanelekileyo.

Imizekelo yoxinzelelo lwegazi olunokuthi lunxibelelane ne-Combivent Respimat lubandakanya:

  • i-diuretics, efana nehydrochlorothiazide, furosemide (Lasix)
  • ii-beta-blockers, ezinje nge-metoprolol (Lopressor), atenolol (Tenormin), propranolol (Inderal)

Ngaphambi kokuba uthathe i-Combivent Respimat, xelela ugqirha wakho ukuba uthatha na la machiza. Banokukutshintshela uxinzelelo lwegazi olwahlukileyo okanye amayeza e-COPD, okanye babeke esweni amanqanaba akho e-potassium.

Impendulo edibeneyo kunye namayeza athile okulwa uxinzelelo

Ukuthatha impendulo ngokudibeneyo kunye namayeza athile oxinzelelo kunokwenza ukuba iziphumo ebezingalindelekanga zibe mbi ngakumbi. (Nceda ujonge icandelo leempendulo "eziHlangeneyo zeMpendulo" ukuze ufumane ezinye iinkcukacha.)

Imizekelo ye-antidepressants enokuthi inxibelelane ne-Combivent Respimat ibandakanya:

  • i-tricyclic antidepressants, enje nge-amitriptyline, nortriptyline (Pamelor)
  • i-monoamine oxidase inhibitors (i-MAOIs), efana ne-phenelzine (Nardil), selegiline (Emsam)

Ngaphambi kokuba uthathe i-Combivent Respimat, xelela ugqirha wakho ukuba uthatha na la machiza. Banokukutshintshela kwi-anti-depressant eyahlukileyo ubuncinci iiveki ezimbini ngaphambi kokuba uqale uthathe i-Combivent Respimat. Ugqirha wakho unokuthatha iyeza elahlukileyo leCOPD.

Impendulo edibeneyo kunye nemifuno kunye nezongezelelo

Akukho naziphi na iiherbs okanye izongezo ezaziwayo zokunxibelelana neCompivent Respimat. Nangona kunjalo, kuya kufuneka ujonge nogqirha wakho okanye usokhemesti ngaphambi kokusebenzisa nayiphi na imifuno okanye izongezo ngelixa uthatha i-Combivent Respimat.

Ukudityaniswa kwempendulo ngokudibeneyo

Sebenzisa ngaphezulu komthamo ocetyiswayo we-Combivent Respimat kunokukhokelela kwiziphumo ebezingalindelekanga ezibi.

Iimpawu libanda

Iimpawu zokudlula ngaphezulu zinokubandakanya:

  • iintlungu zesifuba
  • ukukhawuleza kwentliziyo
  • igazi elonyukayo
  • iinguqulelo ezinamandla zeziphumo ebezingalindelekanga eziqhelekileyo (Nceda ujonge icandelo leziphumo ezihlangeneyo zeMpendulo) ukuze ufumane ezinye iinkcukacha.)

Kufuneka wenze ntoni xa uthe wagqithisa?

Ukuba ucinga ukuba uthathe kakhulu eli chiza, tsalela ugqirha wakho. Ungabiza uMbutho waseMelika wamaZiko oLawulo lweTyhefu ku-800-222-1222 okanye usebenzise isixhobo esikwi-Intanethi. Kodwa ukuba iimpawu zakho zinzima, tsalela umnxeba ku-911 okanye uye kwigumbi likaxakeka elikufutshane ngoko nangoko.

Isebenza njani iMpendulo edibeneyo

Isifo esinganyangekiyo semiphunga (COPD) liqela lezifo zemiphunga ezibandakanya i-bronchitis kunye ne-emphysema.

I-bronchitis engapheliyo ibangela ukuba iityhubhu zomoya kwimiphunga yakho zincinci, zidumbile, kwaye ziqokelele i-mucus. Oku kwenza kube nzima ukuba umoya udlule kwimiphunga yakho.

I-Emphysema itshabalalisa iingxowa zomoya kwimiphunga yakho ngokuhamba kwexesha. Xa kunemingxunya yomoya embalwa, kuba nzima ukuphefumla.

Zombini i-bronchitis enganyangekiyo kunye ne-emphysema zikhokelela kwingxaki yokuphefumla, kwaye kuyinto eqhelekileyo ukuba zombini ezi meko.

Amachiza asebenzayo kwi-Combivent Respimat, ipratropium kunye ne-albuterol, asebenza ngeendlela ezahlukeneyo. Zombini iziyobisi ziyayekelela izihlunu kwiindlela zakho zomoya. Ipratropium ikudidi lweziyobisi ekuthiwa yi-anticholinergics. (Udidi lweziyobisi liqela lamayeza asebenza ngendlela efanayo.) Amachiza akweli klasi anceda ukuthintela izihlunu ezisemiphungeni yakho ziqiniswe.

I-Albuterol ikudidi lweziyobisi ezibizwa ngokuba zi-beta2-agonists (SABAs) ezimfutshane. Amachiza akweli klasi anceda ukukhulula izihlunu kwimiphunga yakho. I-Albuterol ikwanceda ukukhupha i-mucus kwindlela yakho yomoya. Ezi ntshukumo zinceda uvule iindlela zakho zomoya ukwenza ukuphefumla kube lula.

Kuthatha ixesha elingakanani ukusebenza?

Emva kokuba uthathe idosi yempendulo edibeneyo, ichiza kufuneka liqale ukusebenza malunga nemizuzu eli-15. Nje ukuba ichiza liqale ukusebenza, ungaqala uqaphele ukuba kulula ukuphefumla.

Impendulo edibeneyo kunye nokukhulelwa

Akukho datha yaneleyo yokwazi ukuba kukhuselekile na ukuthatha i-Combivent Respimat ngexa ukhulelwe. Nangona kunjalo, isithako kwi-Combivent Respimat esibizwa ngokuba yi-albuterol sibonisiwe senzakalisa abantwana kwizifundo zezilwanyana. Gcina ukhumbula ukuba izifundo zezilwanyana azihlali ziqikelela ukuba kuya kwenzeka ntoni ebantwini.

Ukuba ukhulelwe okanye uceba ukukhulelwa, thetha nogqirha wakho. Banokukuxelela malunga nezibonelelo kunye nomngcipheko wokusebenzisa eli yeza ngelixa ukhulelwe.

Impendulo edibeneyo kunye nolawulo lokuzalwa

Ayaziwa ukuba i-Combivent Respimat ikhuselekile ukuthatha ngexesha lokukhulelwa. Ukuba wena okanye iqabane lakho owabelana nalo ngesondo unokukhulelwa, thetha nogqirha wakho malunga neemfuno zakho zolawulo lokuzalwa ngelixa usebenzisa iCompivent Respimat.

Impendulo edibeneyo kunye nokuncancisa

Akukho datha yaneleyo yokwazi ukuba kukhuselekile ukusebenzisa i-Combivent Respimat ngelixa uncancisa.

Impendulo yokudibanisa inesithako esibizwa ngokuba yi-ipratropium, kunye nenxalenye ye-ipratropium idlula kubisi lwebele. Kodwa akwaziwa ukuba oku kubachaphazela njani abantwana abancancisayo.

Esinye isithako se-Combivent Respimat esibizwa ngokuba yi-albuterol sibonisiwe ukuba senzakalise iintsana kwizifundo zezilwanyana. Nangona kunjalo, izifundo zezilwanyana azihlali ziqikelela ukuba kuya kwenzeka ntoni ebantwini.

Ukuba uncelisa okanye uceba ukuncelisa, thetha nogqirha wakho. Banokukuxelela malunga nezibonelelo kunye nomngcipheko wokusebenzisa eli yeza ngelixa uncancisa.

Imibuzo eqhelekileyo malunga neempendulo eziHlanganisiweyo

Nazi iimpendulo kwimibuzo ebuzwa rhoqo malunga neMpendulo edibeneyo.

Ngaba ndisafuna ukusebenzisa i-inhaler yam yokuhlangula yesiqhelo kunye neMpendulo edibeneyo?

Unga. Inhaler yokuhlangula sisixhobo osisebenzisa kuphela xa unengxaki yokuphefumla kwaye ufuna ukukhululeka kwangoko. Ukudibana kwempendulo, kwelinye icala, sisiyobisi osithathayo rhoqo ukukunceda uqhubeke uphefumle kakuhle. Kodwa kunokubakho amaxesha apho uneengxaki zokuphefumla, ngenxa yoko usenokufuna inhaler yokuhlangula.

Thetha nogqirha wakho malunga nokuba usebenzisa kangaphi inhaler yakho yokuhlangula. Ukuba uyisebenzisa rhoqo, isicwangciso sakho sonyango seCOPD sinokulungiswa.

Ngaba impendulo edibeneyo ingcono kunonyango lwe-albuterol yodwa?

Kusenokwenzeka, ngokophando lweklinikhi lwabantu abanesifo esinganyangekiyo semiphunga (COPD). Abantu bathathe indibaniselwano ye-ipratropium kunye ne-albuterol (iziyobisi ezisebenzayo kwi-Combivent Respimat), i-ipratropium yodwa, okanye i-albuterol iyodwa.

Uphononongo lufumanise ukuba indibaniselwano ye-ipratropium kunye ne-albuterol igcina i-airways ivulekile ixesha elide kunokuba i-albuterol yenze yodwa. Abantu abathathe indibaniselwano yamachiza bavule iindlela zomoya iiyure ezine ukuya kwezintlanu. Oku kuthelekiswa neeyure ezintathu zabantu abathathe ialbuterolol nje.

Phawula: Kolu phononongo, abantu abathathe indibaniselwano ye-ipratropium kunye ne-albuterol basebenzise isixhobo sokuphefumla esahlukileyo kunesixhobo esiHlangeneyo seMpendulo.

Ukuba unemibuzo malunga nealbuterol okanye olunye unyango lweCOPD, thetha nogqirha wakho.

Ngaba zikhona izitofu zokugonya endinokuzifumana ukunciphisa umngcipheko weCOPD?

Ewe. Amaziko oLawulo lweNtsholongwane kunye noThintelo (CDC) acebisa ukuba abantu abaneCOPD bafumana umkhuhlane, inyumoniya, kunye nogonyo lweTdap. Ukufumana ezi zitofu kunokunceda ukunciphisa umngcipheko we-COPD flare-ups.

Kungenxa yokuba usulelo lwemiphunga olufana nomkhuhlane, inyumoniya, kunye nokukhohlela kungenza iCOPD ibe mandundu. Kwaye ukuba neCOPD kunokubangela umkhuhlane, inyumoniya, kunye nokukhohlela.

Unokufuna ezinye izitofu zokugonya, ngokunjalo, cela ugqirha wakho ukuba unolwazi kuzo zonke iifoto zakho.

Yahlula njani iAdviveat Respimat kwiDuoNeb?

I-Respimat edibeneyo kunye ne-DuoNeb bobabini bavunywa yi-Food and Drug Administration (FDA) ukunyanga i-COPD. Nangona kunjalo, iDuoNeb ayisasebenzi kwimarike. I-DuoNeb ngoku iza ngohlobo oluqhelekileyo njenge-ipratropium / albuterol.

Zombini iimpendulo ezidibeneyo kunye ne-ipratropium / albuterol zine-ipratropium kunye ne-albuterol, kodwa amayeza eza ngeendlela ezahlukeneyo. Impendulo edibeneyo iza njengesixhobo esibizwa ngokuba yi-inhaler. Uphefumla iyeza njengesixinzelelo sokutshiza (ierosol) ngokusebenzisa inhaler. Ipratropium / albuterol iza njengesisombululo (umxube wolwelo) esetyenziswe kwisixhobo esibizwa ngokuba yi-nebulizer. Esi sixhobo siguqula iyeza libe yinkungu oyifaka ngaphakathi kwimaski okanye kumlomo.

Ukuba unemibuzo malunga neCompivent Respimat, ipratropium / albuterol, okanye ezinye iindlela zonyango lweCOPD, thetha nogqirha wakho.

Amanyathelo okhuseleko ngokudibeneyo

Ngaphambi kokuba uthathe i-Combivent Respimat, thetha nogqirha wakho malunga nembali yakho yezempilo. Impendulo edibeneyo ayinakulunga kuwe ukuba uneemeko ezithile zonyango okanye ezinye izinto ezichaphazela impilo yakho. Oku kubandakanya:

  • Ukunyanga komzimba. Ukuba uxabana neCombivent Respimat, nasiphi na isithako sayo, okanye i-atropine yeziyobisi, akufuneki uthathe i-Combivent Respimat. (I-Atropine sisiyobisi esifana nekhemikhali esinye sezithako ezikwi-Combivent Respimat.) Ukuba awuqinisekanga ukuba ngaba awunalo naliphi na kula machiza, thetha nogqirha wakho. Banokuncoma unyango olwahlukileyo xa kufuneka njalo.
  • Iimeko ezithile zentliziyo. Ukuphendula ngokudibeneyo kunokubangela iingxaki zentliziyo ukuba uneemeko ezithile zentliziyo. Oku kubandakanya i-arrhythmia, uxinzelelo lwegazi oluphezulu, okanye ukungonelanga kwe-coronary (ukunciphisa ukuhamba kwegazi ukuya entliziyweni). Iyeza linokubangela utshintsho kuxinzelelo lwegazi, ukubetha kwentliziyo, kunye nesingqisho sentliziyo. Ukuba unesifo sentliziyo, buza ugqirha wakho ukuba ngaba i-Combivent Respimat ikulungele na.
  • I-glaucoma emxinwa. Ukuphendula ngokudibeneyo kunokunyusa uxinzelelo emehlweni, oko kunokukhokelela kukutsha okanye ukuhla kweglaucoma emxinwa. Ukuba unayo le fomu ye-glaucoma, ugqirha wakho uya kukujonga ngexesha lonyango lwakho lwe-Combivent Respimat.
  • Iingxaki ezithile zomchamo. Impendulo edibeneyo inokubangela ukugcinwa komchamo, imeko apho isinyi sakho singabinanto ngokupheleleyo. Ukuba uneengxaki ezithile zomchamo ezinje ngeprostate eyandisiweyo okanye isithintelo sentamo yesinyi, buza ugqirha wakho ukuba ngaba Impendulo edibeneyo ilungile na kuwe.
  • Iingxaki zokubanjwa. I-Albuterol, elinye lamachiza kwi-Combivent Respimat, linokuzenza mandundu iingxaki zokuthimba. Ukuba unengxaki yokuthimba, buza ugqirha wakho ukuba ngaba i-Combivent Respimat ikulungele na.
  • Hyperthyroidism. I-Albuterol, elinye lamachiza kwi-Combivent Respimat, linokuba mandundu i-hyperthyroidism (amanqanaba aphezulu e-thyroid). Ukuba unehyperthyroidism, buza ugqirha wakho ukuba ngaba Impendulo edibeneyo ilungile na kuwe.
  • Seswekile. IAlbuterol, elinye lamachiza kwiCompivent Respimat, linokusenza mandundu isifo seswekile. Ukuba unesifo seswekile, buza ugqirha wakho ukuba ngaba Impendulo edibeneyo ilungile na kuwe.
  • Ukukhulelwa kunye nokuncancisa. Ayaziwa ukuba i-Combivent Respimat iyingozi ngexesha lokukhulelwa kunye nokuncancisa. Ngolwazi oluthe kratya, nceda ubone icandelo le- "Combivent Respimat kunye nokukhulelwa" kunye ne "Combivent Respimat kunye nokuncancisa" apha ngasentla.

Phawula: Ngolwazi oluthe kratya malunga neziphumo ezibi ezinokubakho zeempendulo eziHlanganisiweyo, jonga icandelo le- "Iziphumo ezihlangeneyo zokuPhendula" kwicandelo elingasentla.

Ukuphela kokuphendula ngokudibeneyo, ukugcinwa kunye nokulahlwa

Xa ufumana Impendulo edibeneyo kwikhemesti, usokhemesti uya kongeza umhla wokuphelelwa kwileyibhile esebhotileni. Lo mhla uqhelekile ukuba ube ngunyaka omnye ukusukela kumhla wokuhambisa kwabo amayeza.

Umhla wokuphelelwa unceda ekuqinisekiseni ukusebenza kwamayeza ngeli xesha. Isimo sangoku soLawulo lwezoKutya kunye noLawulo lweziyobisi (i-FDA) kukuphepha ukusebenzisa amayeza aphelelwe lixesha. Ukuba awusebenzisanga iyeza elidlulileyo kumhla wokuphelelwa kwalo, thetha nosokhemesti wakho malunga nokuba unganako na ukuyisebenzisa.

Nje ukuba ufake ikhatriji yamayeza kwi-inhaler, ulahle nayiphi na iMpendulo yokuDibanisa esele ihleli emva kweenyanga ezintathu. Oku kusebenza nokuba ngaba awuthathanga naliphi na ichiza.

Ukugcina

Ukuhlala ixesha elingakanani iyeza lihlala lilungile kunokuxhomekeka kwizinto ezininzi, kubandakanya ukuba uligcina phi kwaye phi na iyeza.

Kuya kufuneka ugcine Impendulo edibeneyo kubushushu begumbi. Musa ukuyiqandisa iyeza.

Ukulahla

Ukuba akusafuneki uthathe i-Combivent Respimat kwaye unamayeza ashiyekileyo, kubalulekile ukuba uyilahle ngokukhuselekileyo. Oku kunceda ukuthintela abanye, kubandakanya abantwana kunye nezilwanyana zasekhaya, ekubeni bathathe iyeza ngengozi. Kuyanceda ukugcina ichiza lingonzakalisi okusingqongileyo.

Iwebhusayithi ye-FDA ibonelela ngeengcebiso ezininzi eziluncedo ngokulahla amayeza. Unokucela ikhemesti yakho ukuba ikwazi ukuba ulahla njani na amayeza akho.

Iinkcukacha zobungcali kwiPhendula ngokudibeneyo

Olu lwazi lulandelayo lubonelelwe ngoochwephesha kunye nabanye abaqeqeshi bezempilo.

Iimpawu

Impendulo edibeneyo ibonakalisiwe njengonyango olongezelelekileyo lwesifo esinganyangekiyo semiphunga (i-COPD) xa isigulana singenayo impendulo eyaneleyo (i-bronchospasms eqhubekayo) kwi-bronchodilator yabo yangoku.

Indlela yokusebenza

Impendulo yokudibanisa ibronchodilator equlathe ipratropium bromide (anticholinergic) kunye nealbuterol sulfate (beta2-adrenergic agonist). Xa zidityanisiwe, zibonelela ngokuqina kwempumlo ngokwandisa i-bronchi kunye nezihlunu eziphumlayo kunokuba zisetyenziswe zodwa.

I-Pharmacokinetics kunye ne-metabolism

Isiqingatha sobomi se-ipratropium bromide emva kokuphefumla okanye ukulawulwa kwe-intravenous malunga neeyure ezimbini. Ubomi besiqingatha seAlbuterol sulphate ziiyure ezimbini ukuya kwezintandathu emva kokuphefumla kunye neeyure ezingama-3.9 emva kolawulo lwe-IV.

Ukungqinelana

Ukuphendula ngokudibeneyo kuyaphikiswa kwizigulana eziye zafumana iimpendulo ze-hypersensitivity to:

  • ipratropium, albuterol, okanye nasiphi na isithako esikwiMpendulo edibeneyo
  • i-atropine okanye nantoni na evela kwi-atropine

Ukugcina

Impendulo edibeneyo kufuneka igcinwe kwi-77 ° F (25 ° C), kodwa i-59 ° F ukuya kwi-86 ° F (15 ° C ukuya kwi-30 ° C) yamkelekile. Musa ukubanda.

Iphepha elichazayo ukuba awusenanto oyifunayo: Iindaba zezoNyango namhlanje zenze zonke iinzame zokuqinisekisa ukuba zonke iinkcukacha zichanekile, zibanzi kwaye zihlaziyiwe. Nangona kunjalo, eli nqaku akufuneki lisetyenziswe endaweni yolwazi kunye nobuchule bengcali yezempilo enelayisensi. Kuya kufuneka usoloko uqhagamshelana nogqirha wakho okanye nolunye uqeqesho kwezonyango ngaphambi kokuba uthathe nawaphi na amayeza. Ulwazi lweziyobisi oluqulethwe apha luyakwazi ukutshintsha kwaye alujoliswanga ekusetyenzisweni konke okunokwenzeka, imikhombandlela, izilumkiso, izilumkiso, ukuhlangana kweziyobisi, ukungahambelani komzimba, okanye iziphumo ezibi. Ukungabikho kwezilumkiso okanye olunye ulwazi ngesiyobisi esinikiweyo akubonisi ukuba indibaniselwano yeziyobisi ikhuselekile, iyasebenza, okanye ifanelekile kuzo zonke izigulana okanye konke ukusetyenziswa okuthile.

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